Most online databases that enlist properties of human genes only include information from hand full of resources. To create the Harmonizome mobile app, we assembled, extracted, and organized knowledge from over 60 online resources, including novel databases that we created. The Harmonizome serves this accumulated knowledge in an easy to access interface where users can enter their gene of interest to discover properties of genes. The knowledge spans many bioinformatics systems biology resources from expression in cells, tissues and diseases; regulation by transcription factors, chromatin marks and microRNAs; functional membership in protein complexes, pathways and ontologies; genomic associations with disease, and differential expression upon treatment of human cells with drugs; as well as structural and other genomic features.
The knowledge provided within this app is a subset of the Harmonizome project which can be accessed at:
This project is being actively developed by the Ma'ayan Lab from the Icahn School of Medicine at Mount Sinai in New York, which is part of the BD2K-LINCS Data Coordination and Integration Center (DCIC) supported by NIH grant U54HL127624; and the Knowledge Management Center for Illuminating the Druggable Genome (KMC-IDG) supported by NIH grant U54CA189201.