The e-QoL app is an ICONA Foundation project consisting of a series of questionnaires (PROs) for collecting data on the living and health conditions of people with HIV included in the ICONA cohort study. A Patient Reported Outcome (PRO) is defined as any indication reported directly by the patient without the involvement of the doctor or any other professional figure. The measurement of PROs has also been shown in numerous studies to be of significant utility, reflecting patients' experiences of living with the chronic condition of HIV. For this reason the proposed questionnaires, collected with the support of this app are fundamental for an appropriate analysis by the scientific community of the aspects they investigate.