Drup is a pick up and play type game. You play as a glowing white orb where you defend yourself red enemy orbs. You use your tail to engulf them and stop incoming attacks. If a red enemy orb hits the larger white orb, which you are controlling, the game is over.
The more you play, the more Evolve Points you earn. You can use the Evolve Points to buy upgrades and change up the gameplay.