It has become clear that the current pharmacological nomenclature of psychotropic medications does not reflect our contemporary knowledge, nor does it inform properly the clinician of neuroscience-based prescriptions. Very often we prescribe “antidepressants” for “anxiety” disorders or “second-generation antipsychotics” to depressed patients.
This practice is confusing.
• Five international organizations ECNP, ACNP, AsCNP, CINP & IUPHAR decided five years ago to establish a taskforce and gave it the mission to embed our current neuroscience advances in the nomenclature.
• The scope is to include all the medications with CNS indications and to harness this new nomenclature to help clinicians when they are trying to figure out what would be the next rational “neuropsychopharmacological step”.
• In this second edition 22 new medications were added so NbN includes now 130 medications.
This proposed nomenclature aims to reflect the current pharmacological knowledge base and cannot necessarily represent the ultimate scientific truth.
The taskforce that assembled could have taken the stand that our current knowledge base is not enough to define the primary target or the correct mechanisms of action. But as a taskforce, we feel that it’s better to present a cutting-edge scientific interpretation than to wait for the definitive conclusion. We need to treat our patients now, and we cannot postpone treatment until all the facts are known.

Therefore this nomenclature is based on:
1. The need to treat now.
2. Updated neuroscience insights.
3. The judgment of the members of the taskforce.
Along these lines, we have come up with the following proposal:
The Nomenclature:
Pharmacology and Mode of Action – reflects the current knowledge and understanding about the targeted neurotransmitter/ molecule/system being modified and the mode/mechanism of action.
We also added 4 additional dimensions
4 Additional Dimensions:
Approved Indications – based on the recommendations of major regulatory bodies (e.g. FDA, EMA, etc.)
Efficacy and Side Effects – Driven from positive single, large, RCT and/or “heavy solid weight” clinical data. Only prevalent or life-threatening side effects were included
Practical Note – Summarizes the clinical knowledge that has been "filtered" through the taskforce's "sieve"
Neurobiology – This dimension is focused on the biology. It is divided into preclinical and clinical sections, with the emphasis on the latter
For those who would like to know more abo derived from empirical data.ut the pharmacology, there is a direct link to the relevant site of IUPHAR – our collaborator in this endeavour.

As this is on-going process, we recognize that the product is imperfect. Based on your feedback (and taking into account the feedback of other colleges) new reports and findings, appropriate updates (e.g. later editions) will be undertaken.

To je postalo jasno, da sedanja farmakološko nomenklatura psihotropnih zdravil ne odraža našo sodobno znanje, niti ne pravilno obvesti klinika receptov, ki temelji na nevroznanosti. Zelo pogosto se predpiše "antidepresivi" za "anksioznih" motenj ali "druge generacije antipsihotiki" do depresivnih bolnikov.
Ta praksa je zmedeno.
• Pet mednarodne organizacije ECNP, ACNP, AsCNP, komisarja islandske drţavne in IUPHAR odločila pred petimi leti, da vzpostavi delovno skupino in ji je dal nalogo, da bi vgradili naše sedanje nevrologije napredek v nomenklaturi.
• Obseg je vključiti vsa zdravila z označbami centralnega živčnega sistema in izkoristiti to novo nomenklaturo za pomoč zdravnikom, ko so poskušali ugotoviti, kaj bo naslednji racionalno "Nevropsihofarmakološki korak".
• V drugi izdaji smo dodali 22 novih zdravil tako NBN ima zdaj 130 zdravil.
Namen predlagane nomenklatura, da odražajo trenutno farmakološko bazo znanja in ne predstavljajo nujno končni znanstveno resnico.
Delovna skupina, ki sestavljeni bi v stojalo, da je naša trenutna baza znanja, ni dovolj, da določite primarni cilj ali pravilne mehanizme delovanja. Ampak kot delovne skupine, menimo, da je bolje, da predstaviti vrhunske znanstvene razlage je, kot počakati na dokončen sklep. Moramo za zdravljenje naših bolnikov zdaj, in ne moremo preložiti obravnavo, dokler niso znani vsa dejstva.
 
Zato je ta nomenklatura, ki temelji na:
1. Potreba po zdaj zdravljenje.
2. Posodobljene Neuroscience vpogled.
3. Sodba članov delovne skupine.
V skladu s tem smo prišli do naslednjega predloga:
Nomenklatura:
Farmakologija in način delovanja - odraža trenutno znanje in razumevanje o ciljni živčnega prenašalca / molekule / sistema, ki se spremenjene in načina / mehanizma delovanja.
 Dodali smo še 4 dodatne razsežnosti
4 Dodatna Dimenzije:
Odobreno Indikacije - ki temelji na priporočilih glavnih regulatornih organov (npr FDA, EMA, itd)
Učinkovitost in neželeni učinki - Driven iz pozitivnega samega, veliki, RCT in / ali "težka trdne mase" kliničnih podatkov. so bili vključeni le prevladujoče ali življenjsko nevarne neželene učinke
Praktično Opomba - Povzema klinično znanje, ki je bilo "filtrirana" skozi delovne skupine je "sito"
Nevrobiologija - Ta dimenzija se osredotoča na biologiji. Razdeljen je na predkliničnih in kliničnih oddelkov, s poudarkom na slednji
Za tiste, ki bi radi izvedeli več abo izhaja iz empiričnih data.ut farmakologijo, obstaja neposredna povezava na ustreznem mestu IUPHAR - našega sodelavca v teh prizadevanjih.
 
Kot je to v teku postopek, se zavedamo, da je izdelek nepopolno. Glede na vaše povratne informacije (in ob upoštevanju povratnih informacij drugih šol) nova poročila in ugotovitve, potrebne posodobitve (npr kasnejše izdaje) bodo izvedene.