The first edition of Biostatistics: A Methodology for the HealthSciences has served professionals and students alike as a leadingresource for learning how to apply statistical methods to thebiomedical sciences. This substantially revised Second Editionbrings the book into the twenty-first century for today’saspiring and practicing medical scientist.
This versatile reference provides a wide-ranging look at basicand advanced biostatistical concepts and methods in a formatcalibrated to individual interests and levels of proficiency.Written with an eye toward the use of computer applications, thebook examines the design of medical studies, descriptivestatistics, and introductory ideas of probability theory andstatistical inference; explores more advanced statistical methods;and illustrates important current uses of biostatistics.
New to this edition are discussions ofLongitudinal data analysisRandomized clinical trialsBayesian statisticsGEEThe bootstrap method
Enhanced by a companion Web site providing data sets, selectedproblems and solutions, and examples from such current topics asHIV/AIDS, this is a thoroughly current, comprehensive introductionto the field.
"For a beginner [this book] is a treasure trove; for anexperienced person it can provide new ideas on how better to pursuethe subject of applied statistics."
—Journal of Quality Technology
Sensibly organized for quick reference, Statistical Rules ofThumb, Second Edition compiles simple rules that arewidely applicable, robust, and elegant, and each captures keystatistical concepts. This unique guide to the use of statisticsfor designing, conducting, and analyzing research studiesillustrates real-world statistical applications through examplesfrom fields such as public health and environmental studies. Alongwith an insightful discussion of the reasoning behind everytechnique, this easy-to-use handbook also conveys the variouspossibilities statisticians must think of when designing andconducting a study or analyzing its data.
Each chapter presents clearly defined rules related toinference, covariation, experimental design, consultation, and datarepresentation, and each rule is organized and discussed under fivesuccinct headings: introduction; statement and illustration of therule; the derivation of the rule; a concluding discussion; andexploration of the concept's extensions. The author also introducesnew rules of thumb for topics such as sample size for ratioanalysis, absolute and relative risk, ANCOVA cautions, anddichotomization of continuous variables. Additional features of theSecond Edition include:Additional rules on Bayesian topics
New chapters on observational studies and Evidence-BasedMedicine (EBM)
Additional emphasis on variation and causation
Updated material with new references, examples, and sources
A related Web site provides a rich learning environment andcontains additional rules, presentations by the author, and amessage board where readers can share their own strategies anddiscoveries. Statistical Rules of Thumb, SecondEdition is an ideal supplementary book for courses inexperimental design and survey research methods at theupper-undergraduate and graduate levels. It also serves as anindispensable reference for statisticians, researchers,consultants, and scientists who would like to develop anunderstanding of the statistical foundations of their researchefforts. A related website www.vanbelle.org provides additionalrules, author presentations and more.
Design and Analysis of Experiments in the Health Sciences provides a balanced presentation of design and analysis issues relating to data in the health sciences and emphasizes new research areas, the crucial topic of clinical trials, and state-of-the- art applications.
Advancing the idea that design drives analysis and analysis reveals the design, the book clearly explains how to apply design and analysis principles in animal, human, and laboratory experiments while illustrating topics with applications and examples from randomized clinical trials and the modern topic of microarrays. The authors outline the following five types of designs that form the basis of most experimental structures:Completely randomized designsRandomized block designsFactorial designsMultilevel experimentsRepeated measures designs
A related website features a wealth of data sets that are used throughout the book, allowing readers to work hands-on with the material. In addition, an extensive bibliography outlines additional resources for further study of the presented topics.
Requiring only a basic background in statistics, Design and Analysis of Experiments in the Health Sciences is an excellent book for introductory courses on experimental design and analysis at the graduate level. The book also serves as a valuable resource for researchers in medicine, dentistry, nursing, epidemiology, statistical genetics, and public health.