Sex organ

Male Accessory Sex Organs: Structure and Function in Mammals investigates the salient features of subcellular structure and function of some sex hormone-dependent organs as well as the molecular hormonal mechanisms that regulate them. It describes the embryology, anatomy, and histology of the male sex accessory glands, along with hormonal regulation of fine structure, effects of nutrition on male accessory organs, and uptake and retention of androgens in these organs.
Organized into three sections comprised of 19 chapters, this book begins with an overview of the ultrastructural organization, nutritional requirements, and chief functional properties of the main sex accessory glands in males. It then discusses the molecular mechanisms of hormone action, immunological aspects and systematic abnormalities of some of these male accessory sex organs, pituitary secretion of gonadotropins, fine structural aspects of cytodifferentiation, and biochemical and functional properties related to sperm metabolism and fertility. Other chapters focus on zinc in male sex accessory organs, the role of lysosomal enzymes, the effects of androgens on DNA and RNA synthesis in sex accessory tissue, and the experimental carcinogenesis of the prostate. The book includes in vivo and in vitro studies on prostatic carcinoma and concludes with a chapter on functional and structural changes in male accessory sex organs during aging.
This book is invaluable to biomedical scientists, pathologists, and researchers interested in the biology and pathology of male accessory sex organs.
E. GRUNDMANN, and W. VAHLENSIECK In recent years tumors of the male genital system have acquired a new scientific importance in many respects: First, epidemiologic studies have revealed a striking increase of prostate carcinoma in northwestern Europe and in the USA; it is now counted among the most frequent malig nant tumors in males. Geographic and ethnic distributions suggest that this tumor, too, may be triggered by exogenous factors of a still unknown nature. Histologic classification of malignant tumors of the prostate and testes has attained a certain finality, and the clinical relevance of the stages is recognized. Diagnosis by histology is now supplemented by aspiration biopsy cytology which offers a ready and reliable diagnostic potential. Its safety even surpasses that of punch biopsy histology and supports the qualification of cytology as a screening method. In the Federal Republic of Germany prostate carcinoma was recently included in the cancer prophylaxis program of the social insurance sys tem: Every man over 45 is entitled to one prophylactic free examination per year. Although the number of patients profiting from this opportu nity is still rather small, the number of patients is steadily growing who, as a result of this prophylactic examination, received medical treatment at an early stage of the disease and with a relatively better prognosis1 . Topical problems of social medicine are discussed in this context, as well as plans and developments of the social health service and of the supporting organizations, the federal societies for cancer campaign.
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