From a renowned historian comes a groundbreaking narrative of humanity’s creation and evolution—a #1 international bestseller—that explores the ways in which biology and history have defined us and enhanced our understanding of what it means to be “human.”
One hundred thousand years ago, at least six different species of humans inhabited Earth. Yet today there is only one—homo sapiens. What happened to the others? And what may happen to us?
Most books about the history of humanity pursue either a historical or a biological approach, but Dr. Yuval Noah Harari breaks the mold with this highly original book that begins about 70,000 years ago with the appearance of modern cognition. From examining the role evolving humans have played in the global ecosystem to charting the rise of empires, Sapiens integrates history and science to reconsider accepted narratives, connect past developments with contemporary concerns, and examine specific events within the context of larger ideas.
Dr. Harari also compels us to look ahead, because over the last few decades humans have begun to bend laws of natural selection that have governed life for the past four billion years. We are acquiring the ability to design not only the world around us, but also ourselves. Where is this leading us, and what do we want to become?
Featuring 27 photographs, 6 maps, and 25 illustrations/diagrams, this provocative and insightful work is sure to spark debate and is essential reading for aficionados of Jared Diamond, James Gleick, Matt Ridley, Robert Wright, and Sharon Moalem.
We live in a world of great and increasing complexity, where even the most expert professionals struggle to master the tasks they face. Longer training, ever more advanced technologies—neither seems to prevent grievous errors. But in a hopeful turn, acclaimed surgeon and writer Atul Gawande finds a remedy in the humblest and simplest of techniques: the checklist. First introduced decades ago by the U.S. Air Force, checklists have enabled pilots to fly aircraft of mind-boggling sophistication. Now innovative checklists are being adopted in hospitals around the world, helping doctors and nurses respond to everything from flu epidemics to avalanches. Even in the immensely complex world of surgery, a simple ninety-second variant has cut the rate of fatalities by more than a third.
In riveting stories, Gawande takes us from Austria, where an emergency checklist saved a drowning victim who had spent half an hour underwater, to Michigan, where a cleanliness checklist in intensive care units virtually eliminated a type of deadly hospital infection. He explains how checklists actually work to prompt striking and immediate improvements. And he follows the checklist revolution into fields well beyond medicine, from disaster response to investment banking, skyscraper construction, and businesses of all kinds.
An intellectual adventure in which lives are lost and saved and one simple idea makes a tremendous difference, The Checklist Manifesto is essential reading for anyone working to get things right.
When three-month-old Lia Lee Arrived at the county hospital emergency room in Merced, California, a chain of events was set in motion from which neither she nor her parents nor her doctors would ever recover. Lia's parents, Foua and Nao Kao, were part of a large Hmong community in Merced, refugees from the CIA-run "Quiet War" in Laos. The Hmong, traditionally a close-knit and fiercely people, have been less amenable to assimilation than most immigrants, adhering steadfastly to the rituals and beliefs of their ancestors. Lia's pediatricians, Neil Ernst and his wife, Peggy Philip, cleaved just as strongly to another tradition: that of Western medicine. When Lia Lee Entered the American medical system, diagnosed as an epileptic, her story became a tragic case history of cultural miscommunication.
Parents and doctors both wanted the best for Lia, but their ideas about the causes of her illness and its treatment could hardly have been more different. The Hmong see illness aand healing as spiritual matters linked to virtually everything in the universe, while medical community marks a division between body and soul, and concerns itself almost exclusively with the former. Lia's doctors ascribed her seizures to the misfiring of her cerebral neurons; her parents called her illness, qaug dab peg--the spirit catches you and you fall down--and ascribed it to the wandering of her soul. The doctors prescribed anticonvulsants; her parents preferred animal sacrifices.
Nurses is the compelling story of the year in the life of four nurses, and the drama, unsung heroism, and unique sisterhood of nursing—one of the world’s most important professions (nurses save lives every day), and one of the world’s most dangerous, filled with violence, trauma, and PTSD.
In following four nurses, Alexandra Robbins creates sympathetic characters while diving deep into their world of controlled chaos. It’s a world of hazing—“nurses eat their young.” Sex—not exactly like on TV, but surprising just the same. Drug abuse—disproportionately a problem among the best and the brightest, and a constant temptation. And bullying—by peers, by patients, by hospital bureaucrats, and especially by doctors, an epidemic described as lurking in the “shadowy, dark corners of our profession.”
The result is a page-turning, shocking look at our health-care system.
It's also a book about the destructive power of secrets--both family and government. Her father's hidden liquor bottles, the strange cancers in children in the neighborhood, the truth about what was made at Rocky Flats (cleaning supplies, her mother guessed)--best not to inquire too deeply into any of it.
But as Iversen grew older, she began to ask questions. She learned about the infamous 1969 Mother's Day fire, in which a few scraps of plutonium spontaneously ignited and--despite the desperate efforts of firefighters--came perilously close to a "criticality," the deadly blue flash that signals a nuclear chain reaction. Intense heat and radiation almost melted the roof, which nearly resulted in an explosion that would have had devastating consequences for the entire Denver metro area. Yet the only mention of the fire was on page 28 of the Rocky Mountain News, underneath a photo of the Pet of the Week. In her early thirties, Iversen even worked at Rocky Flats for a time, typing up memos in which accidents were always called "incidents."
And as this memoir unfolds, it reveals itself as a brilliant work of investigative journalism--a detailed and shocking account of the government's sustained attempt to conceal the effects of the toxic and radioactive waste released by Rocky Flats, and of local residents' vain attempts to seek justice in court. Here, too, are vivid portraits of former Rocky Flats workers--from the healthy, who regard their work at the plant with pride and patriotism, to the ill or dying, who battle for compensation for cancers they got on the job.
Based on extensive interviews, FBI and EPA documents, and class-action testimony, this taut, beautifully written book promises to have a very long half-life.
Named on Amazon's Best Books of the Year 2015--Michael Botticelli, U.S. Drug Czar (Politico) Favorite Book of the Year--Angus Deaton, Nobel Prize Economics (Bloomberg/WSJ) Best Books of 2015--Matt Bevin, Governor of Kentucky (WSJ) Books of the Year--Slate.com's 10 Best Books of 2015--Entertainment Weekly's 10 Best Books of 2015 --Buzzfeed's 19 Best Nonfiction Books of 2015--The Daily Beast's Best Big Idea Books of 2015--Seattle Times' Best Books of 2015--Boston Globe's Best Books of 2015--St. Louis Post-Dispatch's Best Books of 2015--The Guardian's The Best Book We Read All Year--Audible's Best Books of 2015--Texas Observer's Five Books We Loved in 2015--Chicago Public Library's Best Nonfiction Books of 2015
From a small town in Mexico to the boardrooms of Big Pharma, an explosive and shocking account of addiction and black tar heroin in the heartland of America.
In 1929, in the blue-collar city of Portsmouth, Ohio, a company built a swimming pool the size of a football field; named Dreamland, it became the vital center of the community. Now, addiction has devastated Portsmouth, as it has hundreds of small rural towns and suburbs across America--addiction like no other the country has ever faced. How that happened is the riveting story of Dreamland.
With a great reporter's narrative skill and the storytelling ability of a novelist, acclaimed journalist Sam Quinones weaves together two classic tales of capitalism run amok whose unintentional collision has been catastrophic. The unfettered prescribing of pain medications during the 1990s reached its peak in Purdue Pharma's campaign to market OxyContin, its new, expensive--extremely addictive--miracle painkiller. Meanwhile, a massive influx of black tar heroin--cheap, potent, and originating from one small county on Mexico's west coast, independent of any drug cartel--assaulted small town and mid-sized cities across the country, driven by a brilliant, almost unbeatable marketing and distribution system. Together these phenomena continue to lay waste to communities from Tennessee to Oregon, Indiana to New Mexico.
Introducing a memorable cast of characters--pharma pioneers, young Mexican entrepreneurs, narcotics investigators, survivors, and parents--Quinones shows how these tales fit together. Dreamland is a revelatory account of the corrosive threat facing America and its heartland.
PEN/Oakland Award Winner
BCALA Nonfiction Award Winner
Gustavus Meyers Award Winner
From the era of slavery to the present day, the first full history of black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment.
Medical Apartheid is the first and only comprehensive history of medical experimentation on African Americans. Starting with the earliest encounters between black Americans and Western medical researchers and the racist pseudoscience that resulted, it details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge—a tradition that continues today within some black populations. It reveals how blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of blacks, and the view that they were biologically inferior, oversexed, and unfit for adult responsibilities. Shocking new details about the government’s notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions.
The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused black Americans to view researchers—and indeed the whole medical establishment—with such deep distrust. No one concerned with issues of public health and racial justice can afford not to read Medical Apartheid, a masterful book that will stir up both controversy and long-needed debate.
From the Trade Paperback edition.
Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years.
The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist.
From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease.
Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
HarperPerennial Classics brings great works of literature to life in digital format, upholding the highest standards in ebook production and celebrating reading in all its forms. Look for more titles in the HarperPerennial Classics collection to build your digital library.
Winner of the National Book Critics Circle Award for Nonfiction
Winner of the 2014 J. Anthony Lukas Book Prize, the PEN/John Kenneth Galbraith Award, the Los Angeles Times Book Prize, the Ridenhour Book Prize, the 2014 American Medical Writers Association Medical Book Award (Public/Healthcare Consumers), a 2014 Science in Society Journalism Award, and the SIBA 2014 Book Award for Nonfiction
An ALA Notable Book, finalist for the NYPL 2014 Helen Bernstein Award, shortlisted for the PEN/E.O. Wilson Award and the ALA Andrew Carnegie Medal
An NPR “Great Reads” Book, a Chicago Tribune Best Book, a Seattle Times Best Book, a Time Magazine Best Book, Entertainment Weekly’s #1 Nonfiction Book, a Christian Science Monitor Best Book, and a Kansas City Star Best Book
Pulitzer Prize winner Sheri Fink’s landmark investigation of patient deaths at a New Orleans hospital ravaged by Hurricane Katrina – and her suspenseful portrayal of the quest for truth and justice.
In the tradition of the best investigative journalism, physician and reporter Sheri Fink reconstructs 5 days at Memorial Medical Center and draws the reader into the lives of those who struggled mightily to survive and to maintain life amid chaos.
After Katrina struck and the floodwaters rose, the power failed, and the heat climbed, exhausted caregivers chose to designate certain patients last for rescue. Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths.
Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.
In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.
Early studies of the human brain used a simple method: wait for misfortune to strike -- strokes, seizures, infectious diseases, horrendous accidents -- and see how victims coped. In many cases their survival was miraculous, if puzzling. Observers were amazed by the transformations that took place when different parts of the brain were destroyed, altering victims' personalities. Parents suddenly couldn't recognize their own children. Pillars of the community became pathological liars. Some people couldn't speak but could still sing.
In The Tale of the Dueling Neurosurgeons, Sam Kean travels through time with stories of neurological curiosities: phantom limbs, Siamese twin brains, viruses that eat patients' memories, blind people who see through their tongues. He weaves these narratives together with prose that makes the pages fly by, to create a story of discovery that reaches back to the 1500s and the high-profile jousting accident that inspired this book's title.* With the lucid, masterful explanations and razor-sharp wit his fans have come to expect, Kean explores the brain's secret passageways and recounts the forgotten tales of the ordinary people whose struggles, resilience, and deep humanity made neuroscience possible.
*"The Tale of the Dueling Neurosurgeons" refers to the case of French king Henri II, who in 1559 was lanced through the skull during a joust, resulting in one of the most significant cases in neuroscience history. For hundreds of years scientists have gained important lessons from traumatic accidents and illnesses, and such misfortunes still represent their greatest resource for discovery.
Every review of One Doctor noted its beautiful writing and compelling story, the riveting tension and suspense. “Remarkable with heart-pounding pace and drama” (Publishers Weekly); “a gripping, moving memoir” (Abraham Verghese); “a terrific read” (The Boston Globe); “an astonishingly moving and incredibly personal account of a modern doctor” (The Lancet).
In compelling first-person prose, Dr. Brendan Reilly takes readers to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests. Filled with fascinating characters in New York City and rural New England—people with dark secrets, mysterious illnesses, impossible dreams, and limitless courage—One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians.
The riveting true story of a small town ravaged by industrial pollution, Toms River melds hard-hitting investigative reporting, a fascinating scientific detective story, and an unforgettable cast of characters into a sweeping narrative in the tradition of A Civil Action, The Emperor of All Maladies, and The Immortal Life of Henrietta Lacks.
One of New Jersey’s seemingly innumerable quiet seaside towns, Toms River became the unlikely setting for a decades-long drama that culminated in 2001 with one of the largest legal settlements in the annals of toxic dumping. A town that would rather have been known for its Little League World Series champions ended up making history for an entirely different reason: a notorious cluster of childhood cancers scientifically linked to local air and water pollution. For years, large chemical companies had been using Toms River as their private dumping ground, burying tens of thousands of leaky drums in open pits and discharging billions of gallons of acid-laced wastewater into the town’s namesake river.
In an astonishing feat of investigative reporting, prize-winning journalist Dan Fagin recounts the sixty-year saga of rampant pollution and inadequate oversight that made Toms River a cautionary example for fast-growing industrial towns from South Jersey to South China. He tells the stories of the pioneering scientists and physicians who first identified pollutants as a cause of cancer, and brings to life the everyday heroes in Toms River who struggled for justice: a young boy whose cherubic smile belied the fast-growing tumors that had decimated his body from birth; a nurse who fought to bring the alarming incidence of childhood cancers to the attention of authorities who didn’t want to listen; and a mother whose love for her stricken child transformed her into a tenacious advocate for change.
A gripping human drama rooted in a centuries-old scientific quest, Toms River is a tale of dumpers at midnight and deceptions in broad daylight, of corporate avarice and government neglect, and of a few brave individuals who refused to keep silent until the truth was exposed.
NAMED ONE OF THE BEST BOOKS OF THE YEAR BY NPR AND KIRKUS REVIEWS
“A thrilling journey full of twists and turns, Toms River is essential reading for our times. Dan Fagin handles topics of great complexity with the dexterity of a scholar, the honesty of a journalist, and the dramatic skill of a novelist.”—Siddhartha Mukherjee, M.D., author of the Pulitzer Prize–winning The Emperor of All Maladies
“A complex tale of powerful industry, local politics, water rights, epidemiology, public health and cancer in a gripping, page-turning environmental thriller.”—NPR
“Unstoppable reading.”—The Philadelphia Inquirer
“Meticulously researched and compellingly recounted . . . It’s every bit as important—and as well-written—as A Civil Action and The Immortal Life of Henrietta Lacks.”—The Star-Ledger
“Fascinating . . . a gripping environmental thriller.”—Kirkus Reviews (starred review)
“An honest, thoroughly researched, intelligently written book.”—Slate
“[A] hard-hitting account . . . a triumph.”—Nature
“Absorbing and thoughtful.”—USA Today
From the Hardcover edition.
Through an objective examination of marijuana and alcohol, and the laws and social practices that steer people toward the latter, the authors pose a simple yet rarely considered question: Why do we punish adults who make the rational, safer choice to use marijuana instead of alcohol? For those unfamiliar with marijuana, Marijuana Is Safer provides an introduction to the cannabis plant and its effects on the user, and debunks some of the government's most frequently cited marijuana myths.
More importantly, for the millions of Americans who want to advance the cause of marijuana policy reform--or simply want to defend their own personal, safer choice--this book provides the talking points and detailed information needed to make persuasive arguments to friends, family, coworkers, elected officials and, of course, future voters.
Suffering a career-ending, potentially crippling injury to her back and right leg, a young dancer named Elaine Petrone tried everyone from orthopedists to yogis to turn her pain and prognosis around. Nothing worked--until she healed herself through a unique program of therapy and exercise based around the use of two small, squishy balls. From there she turned her passion into a mission that is helping the thousands of people who visit her classes conquer pain, stress, and injury.
Now, for relief for sufferers everywhere, comes The Miracle Ball Method. The work itself is simple. Take a sore back: By resting your aching back on grapefruit-sized balls and letting your body sink into them, you're unworking the muscles that hurt. Pain and tension drain out of the body. Petrone shows how proper breathing (which she demonstrates) works in conjunction with a range of unexercises that call for placing the balls under the back, head, knees, hip, elbow--wherever there's pain--and then resting, rolling, or rotating on them. She points out that relief can come in surprising ways: Lower back pain may be helped by placing the ball under your neck, or a bad knee might be helped by hip work. It's a revolutionary program of relief, from head to toe.
Imagine undergoing an operation without anesthesia performed by a surgeon who refuses to sterilize his tools—or even wash his hands. This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.
Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.
Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum.
Award-winning writer Cristin O’Keefe Aptowicz vividly chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals. (Foremost among them: Charles D. Meigs, an influential obstetrician who loathed Mütter’s "overly" modern medical opinions.) In the narrative spirit of The Devil in the White City, Dr. Mütter’s Marvels interweaves an eye-opening portrait of nineteenth-century medicine with the riveting biography of a man once described as the "P. T. Barnum of the surgery room."
A National Book Critics Circle Award Finalist
A New York Times Book Review Top 10 Book of the Year
A Facebook "Year of Books" Selection
One of the Best Books of the Year
* National Book Critics Circle Award finalist * The New York Times Book Review (Top 10) * Entertainment Weekly (Top 10) * New York Magazine (Top 10)* Chicago Tribune (Top 10) * Publishers Weekly (Top 10) * Time Out New York (Top 10) * Los Angeles Times * Kirkus * Booklist * NPR's Science Friday * Newsday * Slate * Refinery 29 * And many more...
Why do we fear vaccines? A provocative examination by Eula Biss, the author of Notes from No Man's Land, winner of the National Book Critics Circle Award
Upon becoming a new mother, Eula Biss addresses a chronic condition of fear-fear of the government, the medical establishment, and what is in your child's air, food, mattress, medicine, and vaccines. She finds that you cannot immunize your child, or yourself, from the world.
In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond. On Immunity is a moving account of how we are all interconnected-our bodies and our fates.
In 1974, Paul Monette met Roger Horwitz, the man with whom he would share more than a decade of his life. In 1986, Roger died of complications from AIDS. Borrowed Time traces this love story from start to tragic finish. At a time when the medical community was just beginning to understand this mysterious and virulent disease, Monette and others like him were coming to terms with unfathomable loss. This personal account of the early days of the AIDS crisis tells the story of love in the face of death.
A finalist for the National Book Critics Circle Award, Borrowed Time was one of the first memoirs to deal candidly with AIDS and is as moving and relevant now as it was more than twenty-five years ago. Written with fierce honesty and heartwarming tenderness, this book is part love story, part testimony, and part requiem.
This ebook features an illustrated biography of Paul Monette including rare images and never-before-seen documents from the Paul Monette papers of the UCLA Library Special Collections.
Emmy-award winning broadcast journalist and leading Alzheimer’s advocate Meryl Comer’s Slow Dancing With a Stranger is a profoundly personal, unflinching account of her husband’s battle with Alzheimer’s disease that serves as a much-needed wake-up call to better understand and address a progressive and deadly affliction.
When Meryl Comer’s husband Harvey Gralnick was diagnosed with early onset Alzheimer’s disease in 1996, she watched as the man who headed hematology and oncology research at the National Institutes of Health started to misplace important documents and forget clinical details that had once been cataloged encyclopedically in his mind. With harrowing honesty, she brings readers face to face with this devastating condition and its effects on its victims and those who care for them. Detailing the daily realities and overwhelming responsibilities of caregiving, Comer sheds intensive light on this national health crisis, using her personal experiences—the mistakes and the breakthroughs—to put a face to a misunderstood disease, while revealing the facts everyone needs to know.
Pragmatic and relentless, Meryl has dedicated herself to fighting Alzheimer’s and raising public awareness. “Nothing I do is really about me; it’s all about making sure no one ends up like me,” she writes. Deeply personal and illuminating, Slow Dancing With a Stranger offers insight and guidance for navigating Alzheimer’s challenges. It is also an urgent call to action for intensive research and a warning that we must prepare for the future, instead of being controlled by a disease and a healthcare system unable to fight it.
When a deadly diphtheria epidemic swept through Nome, Alaska, in 1925, the local doctor knew that without a fresh batch of antitoxin, his patients would die. The lifesaving serum was a thousand miles away, the port was icebound, and planes couldn't fly in blizzard conditions—only the dogs could make it. The heroic dash of dog teams across the Alaskan wilderness to Nome inspired the annual Iditarod Trail Sled Dog Race and immortalized Balto, the lead dog of the last team whose bronze statue still stands in New York City's Central Park. This is the greatest dog story, never fully told until now.
In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.
When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s “remedy” was either sloppy science or outright fraud.
But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.
Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.
The Invisible Cure is an account of Africa's AIDS epidemic from the inside--a revelatory dispatch from the intersection of village life, government intervention, and international aid. Helen Epstein left her job in the US in 1993 to move to Uganda, where she began work on a test vaccine for HIV. Once there, she met patients, doctors, politicians, and aid workers, and began exploring the problem of AIDS in Africa through the lenses of medicine, politics, economics, and sociology. Amid the catastrophic failure to reverse the epidemic, she discovered a village-based solution that could prove more effective than any network of government intervention and international aid, an intuitive response that calls into question many of the fundamental assumptions about the AIDS in Africa.
Written with conviction, knowledge, and insight, The Invisible Cure will change how we think about the worst health crisis of the past century--and indeed about every issue of global public health.
Tom Brokaw has led a fortunate life, with a strong marriage and family, many friends, and a brilliant journalism career culminating in his twenty-two years as anchor of the NBC Nightly News and as bestselling author. But in the summer of 2013, when back pain led him to the doctors at the Mayo Clinic, his run of good luck was interrupted. He received shocking news: He had multiple myeloma, a treatable but incurable blood cancer. Friends had always referred to Brokaw’s “lucky star,” but as he writes in this inspiring memoir, “Turns out that star has a dimmer switch.”
Brokaw takes us through all the seasons and stages of this surprising year, the emotions, discoveries, setbacks, and struggles—times of denial, acceptance, turning points, and courage. After his diagnosis, Brokaw began to keep a journal, approaching this new stage of his life in a familiar role: as a journalist, determined to learn as much as he could about his condition, to report the story, and help others facing similar battles. That journal became the basis of this wonderfully written memoir, the story of a man coming to terms with his own mortality, contemplating what means the most to him now, and reflecting on what has meant the most to him throughout his life.
Brokaw also pauses to look back on some of the important moments in his career: memories of Nelson Mandela, the Dalai Lama, the fall of the Berlin Wall, the morning of September 11, 2001, in New York City, and more. Through it all, Brokaw writes in the warm, intimate, natural voice of one of America’s most beloved journalists, giving us Brokaw on Brokaw, and bringing us with him as he navigates pain, procedures, drug regimens, and physical rehabilitation. Brokaw also writes about the importance of patients taking an active role in their own treatment, and of the vital role of caretakers and coordinated care.
Generous, informative, and deeply human, A Lucky Life Interrupted offers a message of understanding and empowerment, resolve and reality, hope for the future and gratitude for a well-lived life.
Praise for A Lucky Life Interrupted
“It’s impossible not to be inspired by Brokaw’s story, and his willingness to share it.”—Los Angeles Times
“A powerful memoir of battling cancer and facing mortality . . . Through the prism of his own illness, Brokaw looks at the larger picture of aging in America.”—Booklist (starred review)
“Moving, informative and deeply personal.”—The Daily Beast
“The former NBC News anchor has applied the fact-finding skills and straightforward candor that were his stock in trade during his reporting days to A Lucky Life Interrupted.”—USA Today
“Brokaw doesn’t paste a smiley face on his story. Again and again, the book returns to stories of loss but also of grace, luck and the beauty of having another swing at bat.”—The Washington Post
“Engaging . . . [with] the kind of insight that is typical of Mr. Brokaw’s approach to life and now to illness.”—The Wall Street Journal
“Powerful and courageous . . . [Brokaw] looks ahead to the future with hope.”—Bookreporter
A must-read for any cat lover, Cat Sense challenges our most basic assumptions about cats and promises to dramatically improve their lives—and ours.
It’s no secret that humans and apes share a host of traits, from the tribal communities we form to our irrepressible curiosity. We have a common ancestor, scientists tell us, so it’s natural that we act alike. But not all of these parallels are so appealing: the chimpanzee, for example, can be as vicious and manipulative as any human.
Yet there’s more to our shared primate heritage than just our violent streak. In Our Inner Ape, Frans de Waal, one of the world’s great primatologists and a renowned expert on social behavior in apes, presents the provocative idea that our noblest qualities—generosity, kindness, altruism—are as much a part of our nature as are our baser instincts. After all, we share them with another primate: the lesser-known bonobo. As genetically similar to man as the chimpanzee, the bonobo has a temperament and a lifestyle vastly different from those of its genetic cousin. Where chimps are aggressive, territorial, and hierarchical, bonobos are gentle, loving, and erotic (sex for bonobos is as much about pleasure and social bonding as it is about reproduction).
While the parallels between chimp brutality and human brutality are easy to see, de Waal suggests that the conciliatory bonobo is just as legitimate a model to study when we explore our primate heritage. He even connects humanity’s desire for fairness and its morality with primate behavior, offering a view of society that contrasts markedly with the caricature people have of Darwinian evolution. It’s plain that our finest qualities run deeper in our DNA than experts have previously thought.
Frans de Waal has spent the last two decades studying our closest primate relations, and his observations of each species in Our Inner Ape encompass the spectrum of human behavior. This is an audacious book, an engrossing discourse that proposes thought-provoking and sometimes shocking connections among chimps, bonobos, and those most paradoxical of apes, human beings.
In 1917, John R. Brinkley–America’s most brazen con man–introduced an outlandish surgical method for restoring fading male virility.
It was all nonsense, but thousands of eager customers quickly made “Dr.” Brinkley one of America’s richest men–and a national celebrity. The great quack buster Morris Fishbein vowed to put the country’ s “most daring and dangerous” charlatan out of business, yet each effort seemed only to spur Brinkley to new heights of ingenuity, and the worlds of advertising, broadcasting, and politics soon proved to be equally fertile grounds for his potent brand of flimflam.
Culminating in a decisive courtroom confrontation, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America ripe for the bamboozling.
From the Trade Paperback edition.
An inspiring, surprising, sometimes shocking, and ultimately deeply informative memoir of the high-stakes, high-pressured life of a female heart surgeon
Dr. Kathy Magliato is one of the few female heart surgeons practicing in the world today. She is also a member of an even more exclusive group—those surgeons specially trained to perform heart transplants. Heart Matters is the story of the making of a surgeon who is also a wife and mother. In this powerful and moving memoir, which inspired the NBC series Heart Beat, Dr. Magliato takes us into her highly demanding, physically intense, male-dominated world and shows us how she masterfully works to save patients' lives every day, while also maintaining balance at home. Heart Matters is also a wake-up call to all women about their number one killer - heart disease - and explains how to avoid becoming a victim.
Magliato offers a vivid behind-the-scenes view of what really goes on in an operating room and the real-life drama that occurs there. She shows the passion and commitment between patient and doctor, revealing that, at the end of a long day, it's our hearts that matter most.
Her work is both timeless and timely, and spans disciplines, continents, and millennia. It is underscored by an innate environmentalism and driven by Sussman’s relentless curiosity. She begins at “year zero,” and looks back from there, photographing the past in the present. These ancient individuals live on every continent and range from Greenlandic lichens that grow only one centimeter a century, to unique desert shrubs in Africa and South America, a predatory fungus in Oregon, Caribbean brain coral, to an 80,000-year-old colony of aspen in Utah. Sussman journeyed to Antarctica to photograph 5,500-year-old moss; Australia for stromatolites, primeval organisms tied to the oxygenation of the planet and the beginnings of life on Earth; and to Tasmania to capture a 43,600-year-old self-propagating shrub that’s the last individual of its kind. Her portraits reveal the living history of our planet—and what we stand to lose in the future. These ancient survivors have weathered millennia in some of the world’s most extreme environments, yet climate change and human encroachment have put many of them in danger. Two of her subjects have already met with untimely deaths by human hands.
Alongside the photographs, Sussman relays fascinating – and sometimes harrowing – tales of her global adventures tracking down her subjects and shares insights from the scientists who research them. The oldest living things in the world are a record and celebration of the past, a call to action in the present, and a barometer of our future.
As a science journalist, Harriet Brown has explored this collective longing and fixation from an objective perspective; as a mother, wife, and woman with "weight issues," she has struggled to understand it on a personal level. Now, in Body of Truth, Brown systematically unpacks what's been offered as "truth" about weight and health.
Starting with the four biggest lies, Brown shows how research has been manipulated; how the medical profession is complicit in keeping us in the dark; how big pharma and big, empty promises equal big, big dollars; how much of what we know (or think we know) about health and weight is wrong. And how all of those affect all of us every day, whether we know it or not.
The quest for health and wellness has never been more urgent, yet most of us continue to buy into fad diets and unattainable body ideals, unaware of the damage we're doing to ourselves. Through interviews, research, and her own experience, Brown not only gives us the real story on weight, health, and beauty, but also offers concrete suggestions for how each of us can sort through the lies and misconceptions and make peace with and for ourselves.
This moving biography details Melching's beginnings at the University of Dakar and follows her journey of 40 years in Africa, where she became a social entrepreneur and one of humanity's strongest voices for the rights of girls and women.
Inspirational and beautifully written, However Long the Night: Molly Melching's Journey to Help Millions of African Women and Girls Triumph is a passionate entreaty for all global citizens. This book is published in partnership with the Skoll Foundation, dedicated to accelerating innovations from organizations like Tostan that address the world's most pressing problems.
Little more than one hundred years ago, maps of the world still boasted white space: places where no human had ever trod. Within a few short decades the most hostile of the world’s environments had all been conquered. Likewise, in the twentieth century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremis, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer. Doctors, scientists, and explorers all share a defining trait: they push on in the face of grim odds. Because of their extreme exploration we not only understand our physiology better; we have also made enormous strides in the science of healing.
Drawing on his own experience as an anesthesiologist, intensive care expert, and NASA adviser, Dr. Kevin Fong examines how cuttingedge medicine pushes the envelope of human survival by studying the human body’s response when tested by physical extremes. Extreme Medicine explores different limits of endurance and the lens each offers on one of the systems of the body. The challenges of Arctic exploration created opportunities for breakthroughs in open heart surgery; battlefield doctors pioneered techniques for skin grafts, heart surgery, and trauma care; underwater and outer space exploration have revolutionized our understanding of breathing, gravity, and much more. Avant-garde medicine is fundamentally changing our ideas about the nature of life and death.
Through astonishing accounts of extraordinary events and pioneering medicine, Fong illustrates the sheer audacity of medical practice at extreme limits, where human life is balanced on a knife’s edge. Extreme Medicine is a gripping debut about the science of healing, but also about exploration in its broadest sense—and about how, by probing the very limits of our biology, we may ultimately return with a better appreciation of how our bodies work, of what life is, and what it means to be human.
In The Fever, the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we've invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria's jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.
In Killer Fat, Natalie Boero examines how and why obesity emerged as a major public health concern and national obsession in recent years. Using primary sources and in-depth interviews, Boero enters the world of bariatric surgeries, Weight Watchers, and Overeaters Anonymous to show how common expectations of what bodies are supposed to look like help to determine what sorts of interventions and policies are considered urgent in containing this new kind of disease.
Boero argues that obesity, like the traditional epidemics of biological contagion and mass death, now incites panic, a doomsday scenario that must be confronted in a struggle for social stability. The “war” on obesity, she concludes, is a form of social control. Killer Fat ultimately offers an alternate framing of the nation’s obesity problem based on the insights of the “Health at Every Size” movement.
When Freud and Halsted began their experiments with cocaine in the 1880s, neither they, nor their colleagues, had any idea of the drug's potential to dominate and endanger their lives. An Anatomy of Addiction tells the tragic and heroic story of each man, accidentally struck down in his prime by an insidious malady: tragic because of the time, relationships, and health cocaine forced each to squander; heroic in the intense battle each man waged to overcome his affliction. Markel writes of the physical and emotional damage caused by the then-heralded wonder drug, and how each man ultimately changed the world in spite of it—or because of it. One became the father of psychoanalysis; the other, of modern surgery. Here is the full story, long overlooked, told in its rich historical context.
Medical doctor and economist Christopher Murray began the Global Burden of Disease studies to gain a truer understanding of how we live and how we die. While it is one of the largest scientific projects ever attempted—as breathtaking as the first moon landing or the Human Genome Project—the questions it answers are meaningful for every one of us: What are the world’s health problems? Who do they hurt? How much? Where? Why?
Murray argues that the ideal existence isn’t simply the longest but the one lived well and with the least illness. Until we can accurately measure how people live and die, we cannot understand what makes us sick or do much to improve it. Challenging the accepted wisdom of the WHO and the UN, the charismatic and controversial health maverick has made enemies—and some influential friends, including Bill Gates who gave Murray a $100 million grant.
In Epic Measures, journalist Jeremy N. Smith offers an intimate look at Murray and his groundbreaking work. From ranking countries’ healthcare systems (the U.S. is 37th) to unearthing the shocking reality that world governments are funding developing countries at only 30% of the potential maximum efficiency when it comes to health, Epic Measures introduces a visionary leader whose unwavering determination to improve global health standards has already changed the way the world addresses issues of health and wellness, sets policy, and distributes funding.
Michael J. Sandel's "Justice" course is one of the most popular and influential at Harvard. Up to a thousand students pack the campus theater to hear Sandel relate the big questions of political philosophy to the most vexing issues of the day, and this fall, public television will air a series based on the course. Justice offers readers the same exhilarating journey that captivates Harvard students. This book is a searching, lyrical exploration of the meaning of justice, one that invites readers of all political persuasions to consider familiar controversies in fresh and illuminating ways. Affirmative action, same-sex marriage, physician-assisted suicide, abortion, national service, patriotism and dissent, the moral limits of markets—Sandel dramatizes the challenge of thinking through these con?icts, and shows how a surer grasp of philosophy can help us make sense of politics, morality, and our own convictions as well. Justice is lively, thought-provoking, and wise—an essential new addition to the small shelf of books that speak convincingly to the hard questions of our civic life.
Effectively manage special patient populations with a focus on pediatric, geriatric, and adult patients.
Master the ins and outs of a wide range of diseases, from common to rare, through detailed discussions of each disease’s unique features.Stay at the forefront of your field with the most updated information on each coexisting condition’s definition; current pathophysiology; significant pre-, intra-, and postoperative factors of the disease process; anesthetic judgment; and management.
Keep current with changing patient populations with a new chapter on managing morbidly obese patients.
Access the information you need quickly thanks to a disease-based organization.
Overcome the toughest challenges your with the latest guidelines and evidence integrated into each chapter.
In The Great Starvation Experiment, historian Todd Tucker tells the harrowing story of thirty-six young men who willingly and bravely faced down profound, consuming hunger. As conscientious objectors during World War II, these men were eager to help in the war effort but restricted from combat by their pacifist beliefs. So, instead, they volunteered to become guinea pigs in one of the most unusual experiments in medical history -- one that required a year of systematic starvation.
Dr. Ancel Keys was already famous for inventing the K ration when the War Department asked for his help with feeding the starving citizens of Europe and the Far East at the war's end. Fascists and Communists, it was feared, could gain a foothold in war-ravaged areas. "Starved people," Keys liked to say, "can't be taught Democracy." The government needed to know the best way to rehabilitate those people who had been severely underfed during the long war. To study rehabilitation, Keys first needed to create a pool of starving test subjects.
Gathered in a cutting-edge lab underneath the football stadium at the University of Minnesota, Dr. Keys' test subjects forsook most food and were monitored constantly so that Dr. Keys and his scientists could study the effects of starvation on otherwise healthy people. While the weight loss of the men followed a neat mathematical curve, the psychological deterioration was less predictable. Some men drank quarts and quarts of water to fill their empty stomachs. One man chewed as many as forty packs of gum a day. One man mutilated himself to escape the experiment. Ultimately only four of the men were expelled from the experiment for cheating -- a testament to the volunteers' determination and toughness.
To prevent atrocities of the kind committed by the Nazi doctors, international law now prevents this kind of experimentation on healthy people. But in this remarkable book, Todd Tucker captures a lost sliver of American history -- a time when cold scientific principles collided with living, breathing human beings. Tucker depicts the agony and endurance of a group of extraordinary men whose lives were altered not only for the year they participated in the experiment, but forever.
In her third enthralling book about the brain, Judith Horstman takes us on a lively tour of our most important sex and love organ and the whole smorgasbord of our many kinds of love-from the bonding of parent and child to the passion of erotic love, the affectionate love of companionship, the role of animals in our lives, and the love of God.
Drawing on the latest neuroscience, she explores why and how we are born to love-how we're hardwired to crave the companionship of others, and how very badly things can go without love. Among the findings: parental love makes our brain bigger, sex and orgasm make it healthier, social isolation makes it miserable-and although the craving for romantic love can be described as an addiction, friendship may actually be the most important loving relationship of your life.
Based on recent studies and articles culled from the prestigious Scientific American and Scientific American Mind magazines, The Scientific American Book of Love, Sex, and the Brain offers a fascinating look at how the brain controls our loving relationships, most intimate moments, and our deep and basic need for connection.
Each procedure includes indications, contraindications, preparation, technique, postprocedure management, and prevention and management of complications. Simple line drawings demonstrate relevant anatomy and procedures. Coverage also includes risk management, nursing management, and drugs and dosages. The outline format helps readers find information quickly, and the compact pocket size enables residents and practitioners to carry all the information they need with them.
In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out.
Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.
Anthropologist Emily Martin guides us into the fascinating and sometimes disturbing worlds of mental-health support groups, mood charts, psychiatric rounds, the pharmaceutical industry, and psychotropic drugs. Charting how these worlds intersect with the wider popular culture, she reveals how people living under the description of bipolar disorder are often denied the status of being fully human, even while contemporary America exhibits a powerful affinity for manic behavior. Mania, Martin shows, has come to be regarded as a distant frontier that invites exploration because it seems to offer fame and profits to pioneers, while depression is imagined as something that should be eliminated altogether with the help of drugs.
Bipolar Expeditions argues that mania and depression have a cultural life outside the confines of diagnosis, that the experiences of people living with bipolar disorder belong fully to the human condition, and that even the most so-called rational everyday practices are intertwined with irrational ones. Martin's own experience with bipolar disorder informs her analysis and lends a personal perspective to this complex story.
Some images inside the book are unavailable due to digital copyright restrictions.
The common ancestry of all humanity
The role of genes in sickness and health
Debates over the use of genetic technology
Written in an engaging, narrative manner, this concise introduction is an ideal starting point for anyone who wants to know more about genes, DNA, and the genetic ties that bind us all.
*Concise and portable for “on-the-spot” treatment advice
*Comprehensive overview of the initial evaluation and treatment
*Features the most frequently encountered problems in a specialty
*Includes laboratory and diagnostic tests, procedures, and commonly used medications
*Perfect for residents and students on the wards
Over 80 of the most common internal medicine problems. Thoroughly revised to reflect current practices and treatment options.
ABSITE-style question format familiarizes readers with the test’s presentation and content. This edition features twice the number of questions as in the previous edition, offering even more opportunities for self-paced review. Rationales for correct and incorrect responses help to identify the test-taker’s strengths and weaknesses. This book is ideal not only for those preparing for the ABSITE, but also for surgeons and residents studying for the general surgery qualifying exam and for all surgical residents seeking to review key topics during rotations.