The authors are careful to present new information such that it links it to existing content, ever mindful that students assimilate new information only in the proper context. The enriched assessment content in WileyPLUS Learning Space offers students the opportunity to gauge their conceptual understanding and receive immediate feedback to address misconceptions.
A Clear, Flexible Approach to Chemistry for the Modern Classroom
Active learning, an increased focus on clinical examples, updates based on current teaching and research findings, and digital innovations designed to engage and personalize readers’ experience make Fundamentals of General, Organic, and Biological Chemistry simply the best choice for readers with a future in allied health. With the Eighth Edition, the authors make learning chemistry a more active experience through features designed to get readers doing chemistry. Every chapter features Hands on Chemistry sections that deepen readers’ understanding of chemistry by having them perform elementary experiments with everyday household items. Group Problemsat the end of every chapter are designed for in-class use and motivate readers to carefully think about higher-level problems, such as how concepts fit together and how to apply these concepts in a clinical application. All of the chapter openers, including many of the Chemistry in Action boxes and end-of-chapter problems, have been rewritten for a stronger clinical focus that provides more relevance to allied health majors.
All content has been updated for the modern classroom with special attention to the biochemistry chapters, making the Eighth Edition of Fundamentals of General, Organic and Biological Chemistry the best choice for future allied health readers. This edition is fully integrated with MasteringChemistry to provide an interactive and engaging experience. Media resources include narrated Video Tutor Solutions for every book chapter that present how to work the most challenging problems and feature additional feedback and instruction from contributor Sara Madsen. NEW in MasteringChemistry is the Chemistry Primer, a diagnostic and remediation tool that provides pre-built assignments designed to get readers up to speed on Chemistry and Math skills at the beginning of the course so they come to class prepared to delve more deeply into topics.
Also available as a Pearson eText or packaged with Mastering Chemistry
Pearson eText is a simple-to-use, mobile-optimized, personalized reading experience that can be adopted on its own as the main course material. It lets students highlight, take notes, and review key vocabulary all in one place, even when offline. Seamlessly integrated videos and other rich media engage students and give them access to the help they need, when they need it. Educators can easily share their own notes with students so they see the connection between their eText and what they learn in class – motivating them to keep reading, and keep learning.
Mastering Chemistry is the leading online homework, tutorial, and assessment system, designed to improve results by engaging students before, during, and after class with powerful content. Instructors ensure students arrive ready to learn by assigning educationally effective content before class, and they encourage critical thinking and retention with in-class resources such as Learning Catalytics™. Students can further master concepts after class through traditional and adaptive homework assignments that provide hints and answer-specific feedback. The Mastering gradebook records scores for all automatically graded assignments in one place, while diagnostic tools give instructors access to rich data to assess student understanding and misconceptions.
Note: You are purchasing a standalone book; Pearson eText and Mastering Chemistry do not come packaged with this content. Students, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information.
If your instructor has assigned Pearson eText as your main course material, search for:
• 0135213746 / 9780135213742 Pearson eText Fundamentals of General, Organic, and Biological Chemistry, 8/e -- Access Card
• 0135213754 / 9780135213759 Pearson eText Fundamentals of General, Organic, and Biological Chemistry, 8/e -- Instant Access
If you would like to purchase both the physical text and Mastering Chemistry, search for:
0134033094 / 9780134033099 Fundamentals of General, Organic, and Biological Chemistry Plus MasteringChemistry with eText -- Access Card Package
Package consists of:0134143337 / 9780134143330 MasteringChemistry with Pearson eText -- ValuePack Access Card -- for Fundamentals of General, Organic, and Biological Chemistry 0134015185 / 9780134015187 Fundamentals of General, Organic, and Biological Chemistry
The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function.
This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.
Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids.
The twenty-two chapters explore such topics as:Chemistry, absorption, transport, and metabolism of GSH and sulfur amino acids Antioxidant and detoxification properties of GSH and sulfur amino acids, highlighting the enzymatic systems involved in antioxidant defenses Biological activities of GSH and sulfur amino acids and their role in modulating cell processes Role of GSH and sulfur amino acid deficiency and alteration in the onset of diseases and in aging Protective effects exerted by GSH and sulfur amino acids when used as drugs, functional foods, and nutraceuticals in humans and animals
Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities, as well as the nutritional and therapeutic significance of dietary sulfur amino acids as shown in human and animal models.
With more than 2,000 scientific references, this book provides food scientists, nutritionists, biochemists, food technologists, chemists, molecular biologists, and public health professionals with a comprehensive and up-to-date examination of glutathione and sulfur amino acids in human health and disease.
Updated to reflect the advances of the 21st century, this book offers:An overview of the chemical principles underlying the processes of cross-linking and conjugation A thorough list of cross-linking reagents published in the literature since the first edition, covering monofunctional, homobifunctional, heterobifunctional, multifunctional, and zero-length cross-linkers Reviews of the use of these reagents in studying protein tertiary structures, geometric arrangements of subunits within complex proteins and nucleic acids, near-neighbor analysis, protein-to-protein or ligand–receptor interactions, and conformational changes of biomolecules Discusses the application of immunoconjugation for immunoassays, immunotoxins for targeted therapy, microarray technology for analysis of various biomolecules, and solid state chemistry for immobilizations
The book is focused on the molecular mechanisms of cellular processes in the context of human physiological situations such as fasting, feeding and physical exercise, in which metabolic regulation is highlighted. Furthermore the book uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges.
This book also:Elucidates the foundations of the molecular events of life
Uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges
Provides realistic representations of molecules throughout the book
Advance Praise for Integrative Human Biochemistry
“This textbook provides a modern and integrative perspective of human biochemistry and will be a faithful companion to health science students following curricula in which this discipline is addressed. This textbook will be a most useful tool for the teaching community.”
Director of the Institute for Research in Biomedicine, Barcelona, Spain
President-elect of the International Union of Biochemistry and Molecular Biology, IUBMB
The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
Are you baffled by biochemistry? If so here's the good news ? you don't have to stay that way! Biochemistry For Dummies shows you how to get a handle on biochemistry, apply the science, raise your grades, and prepare yourself to ace any standardized test.
This friendly, unintimidating guide presents an overview of the material covered in a typical college-level biochemistry course and makes the subject easy to understand and accessible to everyone. From cell ultrastructure and carbohydrates to amino acids, proteins, and supramolecular structure, you'll identify biochemical structures and reactions, and send your grades soaring.Newest biology, biochemistry, chemistry, and scientific discoveries Updated examples and explanations Incorporates the most current teaching techniques
From water biochemistry to protein synthesis, Biochemistry For Dummies gives you the vital information, clear explanations, and important insights you need to increase your understanding and improve your performance on any biochemistry test.
Plants are the source of important industrial raw material such as fat and starch but they are also the basis for the production of pharmaceutics. It is expected that in the future, gene technology will lead to the extensive use of plants as a means of producing sustainable raw material for industrial purposes. As such, the techniques and use of genetic engineering to improve crop plants and to provide sustainable raw materials for the chemical and pharmaceutical industries are described in this edition. The latest research findings have been included, and areas of future research are identified.Offers the latest research findings in a concise and understandable mannerPresents plant metabolism in the context of the structure and the function of plantsIncludes more than 300 two-color diagrams and metabolic schemesCovers the various commercial applications of plant biochemistryProvides extensive references to the recent scientific literature
From the coasts of Indonesia to the rainforests of Peru, venomous animals are everywhere—and often lurking out of sight. Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world.
Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out.
Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated.
Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.
Volume 19 focusses on Purinergic receptors, also termed purinoceptors. These are plasma membrane proteins present in nearly all mammalian tissues. They participate in a number of cell functions that include proliferation and migration of neural stem cells, vascular reactivity, apoptosis and cytokine secretion and have been associated with learning and memory, feeding conduct, movement and sleep. They facilitate relaxation of smooth muscle of the gut in response to adenosine (P1 receptors) or ATP (P2 receptors).
The chapters in this volume are authored by experts in the field. They deal with aspects of structure and biological activity of selected receptor proteins. The first chapter in this volume reviews the current research on the Mechanism of channel gating and regulation of the activity of calcium-activated chloride channel ANO1. This is followed by a chapter dealing with Structure and function of the two-component cytotoxins of Staphylococcus aureus and a chapter on Membrane Fusion and Infection involving the Influenza virus Hemagglutinin. The fourth chapter reviews the impact of arrhythmogenic mutations through the structural determination of the L-type voltage-gated calcium channel. Then there is a chapter that discusses some open questions pertaining to histone post-translational modifications and nucleosome organization in transcriptional regulation. The next chapter deals with regulation of the extracellular SERPINA5 (protein C inhibitor) penetration through cellular membranes. This is followed by a chapter on coding of Class I and II aminoacyl-tRNA synthetases; a chapter on regulation of nephrin phosphorylation in diabetes and chronic kidney injury and a chapter on The Structure-Forming Juncture in oxidative protein folding and the events in the ER. Finally the last chapter deals with the polyspecificity of anti-lipid antibodies and its relevance to the development of autoimmunity. This volume is intended for research scientists, clinicians, physicians and graduate students in the fields of biochemistry, cell biology, molecular biology, immunology and genetics.
Chemical biology is a rapidly developing branch of chemistry, which sets out to understand the way biology works at the molecular level. Fundamental to chemical biology is a detailed understanding of the syntheses, structures and behaviours of biological macromolecules and macromolecular lipid assemblies that together represent the primary constituents of all cells and all organisms. The subject area of chemical biology bridges many different disciplines and is fast becoming an integral part of academic and commercial research.
This textbook is designed specifically as a key teaching resource for chemical biology that is intended to build on foundations lain down by introductory physical and organic chemistry courses. This book is an invaluable text for advanced undergraduates taking biological, bioorganic, organic and structural chemistry courses. It is also of interest to biochemists and molecular biologists, as well as professionals within the medical and pharmaceutical industry.
Key Features:A comprehensive introduction to this dynamic area of chemistry, which will equip chemists for the task of understanding and studying the underlying principles behind the functioning of biological macro molecules, macromolecular lipid assemblies and cells. Covers many basic concepts and ideas associated with the study of the interface between chemistry and biology. Includes pedagogical features such as: key examples, glossary of equations, further reading and links to websites. Clearly written and richly illustrated in full colour.
Biochemistry for Medical Professionalscontains pivotal advances in the biochemistry field and provides a resource for professionals across medicine, dentistry, pharmaceutical sciences and health professions who need a concise, topical biochemistry reference.
Relevant, well-illustrated coverage begins with the composition of the human body and then goes into the technical detail of the metabolism of the human body and biochemistry of internal organs before featuring a biotechnology study inclusive of numerous methods and applications.
The work is written at a consistently high level, with technical notes added to aid comprehension for complex topics.Illustrates disease involvement in metabolic mapsContains coverage of cutting-edge technology, including iPS, HPLC and HPLC-MS, and FACS methodProvides in-depth technical detail as well as conceptual frameworks of biochemistry and experimental design in the context of the human organismIncludes a biotechnology study, featuring application of basic biochemistry principles
Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six,contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology. It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information.
It is a valuable tool for advanced graduate students and researchers who are interested in exploring lipid biology in more detail, and includes overviews of lipid biology in both prokaryotes and eukaryotes, while also providing fundamental background on the subsequent descriptions of fatty acid synthesis, desaturation and elongation, and the pathways that lead the synthesis of complex phospholipids, sphingolipids, and their structural variants. Also covered are sections on how bioactive lipids are involved in cell signaling with an emphasis on disease implications and pathological consequences.Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistryReferences from current literature will be included in each chapter to facilitate more in-depth studyKey concepts are supported by figures and models to improve reader understandingChapters provide historical perspective and current analysis of each topic
Part I includes subjects underpinning the book such as a primer on DNA, the broader discipline of nanoscience, and experimental tools used by the principals in the narrative. Part II examines the field of structural DNA nanotechnology, founded by biochemist/crystallographer Nadrian Seeman, that uses DNA as a construction material for nanoscale structures and devices, rather than as a genetic material. Part III looks at the work of physicists Noel Clark and Tommaso Bellini who found that short DNA (nanoDNA) forms liquid crystals that act as a structural gatekeeper, orchestrating a series of self-assembly processes using nanoDNA. This led to an explanation of the polymeric structure of DNA and of how life may have emerged from the prebiotic clutter.
A Doody's Core Title for 2017!
THE BEST REVIEW FOR THE USMLE!
The Thirtieth Edition of Harper’s Illustrated Biochemistry combines outstanding full-colorillustrations with authoritative integrated coverage of biochemical disease and clinical information. Using brevity and numerous medically relevant examples, Harper's presents a clear, succinct review of the fundamentals of biochemistry that every student must understand in order to succeed in medical school.
All fifty-eight chapters emphasize the medical relevance of biochemistryFull-color presentation includes more than 600 illustrations Each chapter includes a section on BiomedicalImportance and a summary of the topics covered Review questions follow each of the eleven sections Case studies in every chapter emphasize the clinical relevance to biochemistry NEW coverage of toxic naturally-occurring amino acids; extraterrestrial biomolecules; computer-aided drug design; the role of complement cascade in bacterial and viral infection; secreted mediators of cell-cell signaling between leukocytes; the role of mast cells, basophils, andeosinophils; and the hazard of antioxidants that down-regulate radical signaling for apoptosis and increase risk of cancer
Applauded by medical students for its current and engaging style, Harper's Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic.
Trying to understand the chemical processes of living organisms but having trouble metabolizing the complex concepts? Here's your lifeline! Biochemistry Demystified helps synthesize your understanding of this important topic.
You'll start with a review of basic chemical concepts and a look at cell structures and cell division. Next, you'll study carbohydrates, lipids, proteins, nucleic acids, nucleotides, and enzymes. Glycolysis, the citric acid cycle, oxidative phosphorylation, and the control of chemical processes round out the coverage. Hundreds of examples and illustrations make it easy to understand the material, and end-of-chapter questions and a final exam help reinforce learning.
This fast and easy guide offers:Numerous figures to illustrate key concepts Details on DNA and RNA Coverage of hormones and neurotransmitters A chapter on analytical techniques and bioinformatics A time-saving approach to performing better on an exam or at work
Simple enough for a beginner, but challenging enough for an advanced student, Biochemistry Demystified is your key to mastering this vital life sciences subject.
Providing a powerful visual overview of the entire spectrum of human biochemistry, the third edition of the popular Color Atlas of Biochemistry is an ideal reference and study aid. It utilizes the signature Flexibook format, consisting of double-page spreads with clear explanatory text on the left-hand page and exquisitely detailed full-color graphics on the right. These bite-sized learning capsules ensure that your review of any given topic is quick, efficient, and comprehensive, allowing you to target the exact information you need for classroom and exam success.
New features of this bestselling review book:Increased focus on pathobiochemical aspects and clinical correlations, especially useful for exam preparation in the clinical sciencesNew and expanded sections on the immune and digestive systems, motor proteins, transport processes, blood clotting and fibrinolysis, biochemistry of fatty tissue, metabolic integration, neurotransmitters and their receptors, signal transduction, and much more!Symbols for atoms, biomolecules, coenzymes, biochemical processes, and chemical reactions are color-coded to promote quick comprehension Computer graphics that provide simulated 3D representations of important molecules, making complex subject matter tangibleConvenient color thumb index that guides you quickly through the book
This superb didactic atlas has been used by medical and health science students worldwide since its first publication in German in 1994. It has since been translated into 9 languages and has been revised and updated regularly ever since. Its unrivalled illustrations, concise text, and focused presentation all combine to create an excellent, high-yield study guide.
Drawn from the perspectives of recent graduates fresh from their medical school and USMLE experience, Deja Review books focus specifically on what is essential for success on your course exams and the USMLE.
Everything you must know about Biochemistry to ace your exams:
Proteins; Metabolism; Nutrition; Molecular Biology; Genetics; Cell Biology and Physiology.
Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical care. Case Files: Biochemistry provides 53 true-to-life cases that illustrate essential concepts in this field. Each case includes an easy-tounderstand discussion correlated to essential basic science concepts, definitions of key terms, biochemistry pearls, and USMLE-style review questions. With Case Files, you'll learn instead of memorize.Learn from 53 high-yield cases, each with board-style questions and key-point pearls Master complex concepts through clear and concise discussions Practice with review questions to reinforce learning Polish your approach to clinical problem-solving Perfect for medical and dental students preparing for course exams and the Boards
Author, John Pelley, wins 2010 Alpha Omega Alpha Robert J. Glaser Distinguished Teacher Award
John Pelley PhD, an associate author of two popular medical review titles, Rapid Review Biochemistry, and Elsevier's Integrated Review Biochemistry has won the 2010 Alpha Omega Alpha (AOA) Robert J. Glaser Distinguished Teacher Award. The award was established by the AOA medical honor society in 1988 to recognize faculty members who have distinguished themselves in medical student education. He is nationally known for applying concept mapping, a learning technique that focuses on building patterns and relationships to concepts, to medical education.Review the most current information with completely updated chapters, images, and questions. Profit from the guidance of series editor, Dr. Edward Goljan, a well-known author of medical review books, who reviewed and edited every question. Take a timed or a practice test online with more than 350 USMLE-style questions and full rationales for why every possible answer is right or wrong. Access all the information you need to know quickly and easily with a user-friendly, two-color outline format that includes High-Yield Margin Notes. Study and take notes more easily with the new, larger page size. Practice with a new testing platform on USMLE Consult that gives you a realistic review experience and fully prepares you for the exam.
500 USMLE-style questions and answers!
Great for course review and the USMLE Step 1, PreTest asks the right questions so you’ll know the right answers. You’ll find 500 clinical-vignette style questions and answers along with complete explanations of correct and incorrect answers. The content has been reviewed by students who recently passed their exams, so you know you are studying the most relevant and up-to-date material possible. No other study guide targets what you really need to know in order to pass like PreTest!
300 FULL-COLOR ILLUSTRATIONS
Medical Biochemistry: The Big Picture is a unique biochemistry review that focuses on the medically applicable concepts and techniques that form the underpinnings of the diagnosis, prognosis, and treatment of medical conditions. Those preparing for the USMLE, residents, as well as clinicians who desire a better understanding of the biochemistry behind a particular pathology will find this book to be an essential reference. Featuring succinct, to-the-point text, more than 300 full-color illustrations, and a variety of learning aids, Medical Biochemistry: The Big Picture is designed to make complex concepts understandable in the shortest amount of time possible.
This full-color combination text and atlas features:Progressive chapters that allow you to build upon what you’ve learned in a logical, effective manner Chapter Overviews that orient you to the important concepts covered in that chapter Numerous tables and illustrations that clarify and encapsulate the text Sidebars covering a particular disease or treatment add clinical relevance to topic discussed Essay-type review questions at the end of each chapter allow you to assess your comprehension of the major topics USMLE-style review questions at the end of each section Three appendices, including examples of biochemically based diseases, a review of basic biochemical techniques, and a review of organic chemistry/biochemistry