Ebola, SARS, Hendra, AIDS, and countless other deadly viruses all have one thing in common: the bugs that transmit these diseases all originate in wild animals and pass to humans by a process called spillover. In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?
If you’re bloated and looking for relief, you’ve come to the right place. In her medical practice The Digestive Center for Women, Dr. Robynne Chutkan has helped thousands of women get back into their skinny jeans, and she can do the same for you. Understanding what’s behind your suffering is the key to deflating for good. The Bloat Cure helps you identify the root cause of your bloat, whether it’s the artificial sweeteners in your sports drink, the cough medicine you’re taking, an undetected thyroid problem, or one of the other 101 common causes.
Once you pinpoint your condition, Dr. Chutkan offers a clear plan of action to stop whatever’s triggering it, rehabilitate your system, and get your GI tract running like a well-oiled machine. Get ready for immediate relief -- and start feeling like yourself again!
From the Hardcover edition.
Why do my jeans fit only in the morning? Why am I always guzzling Pepto-Bismol before a big meeting? Could my PMS cramps mean something serious?
Here, finally, are the answers to these questions, and hundreds more, about the nagging stomach problems that plague so many women. In this reassuring guide, Dr. Jacqueline L. Wolf, a leading expert in the field of gastrointestinal health, explains the causes and cures for women's most common digestive ailments (including bloating, constipation, diarrhea, acid reflux, IBS) and more serious, life-altering conditions like Crohn's disease and endometriosis. This candid book deals with sensitive issues in a down-to-earth way and eradicates once and for all the secrecy and shame surrounding these urgent problems.
This is my story about how gastroparesis has entered my life and how I managed to accomplish my goals while dealing with symptom management on a daily basis. From doctors who told me it was all in my head to doctors who took the chance and gave me a new lease on life. My story includes how I found treatment, the surgeries I endured and my quality of life throughout.
My hope is that through reading this, you will understand more about gastroparesis and what can be done to achieve the best symptom management possible for you or someone you know.
Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are.
The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people.
Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. It will change both our view of nature and our sense of where we belong in it.
Microbiology is a fascinating field that explores life down to the tiniest level. Did you know that your body contains more bacteria cells than human cells? It's true. Microbes are essential to our everyday lives, from the food we eat to the very internal systems that keep us alive. These microbes include bacteria, algae, fungi, viruses, and nematodes. Without microbes, life on Earth would not survive. It's amazing to think that all life is so dependent on these microscopic creatures, but their impact on our future is even more astonishing. Microbes are the tools that allow us to engineer hardier crops, create better medicines, and fuel our technology in sustainable ways. Microbes may just help us save the world.
Microbiology For Dummies is your guide to understanding the fundamentals of this enormously-encompassing field. Whether your career plans include microbiology or another science or health specialty, you need to understand life at the cellular level before you can understand anything on the macro scale.Explore the difference between prokaryotic and eukaryotic cells Understand the basics of cell function and metabolism Discover the differences between pathogenic and symbiotic relationships Study the mechanisms that keep different organisms active and alive
You need to know how cells work, how they get nutrients, and how they die. You need to know the effects different microbes have on different systems, and how certain microbes are integral to ecosystem health. Microbes are literally the foundation of all life, and they are everywhere. Microbiology For Dummies will help you understand them, appreciate them, and use them.
If you are interested in learning everything there is to know about Leaky Gut Syndrome, than this is going to be the most important information you'll ever read...
Just imagine being able to improve your digestion in just 7 days (or less) without becoming frustrated or wasting your time.
And you could do this from the comfort of your own home, wouldn't that be great?
Yes you could have a healthier gut. It truly is possible, but you just need to know how.
That's what "Leaky Gut Syndrome STOP!" can help you do - Plus you can....
Detoxify Your Body And Improve Your Overall Health In Just 7 Days
Here's what you'll discover in Leaky Gut Syndrome STOP!:
- How leaky gut syndrome affects your body and overall health...
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- 3 proven steps to diagnosing leaky gut syndrome...
- 2 simple keys (that are right in front of your eyes) to rebalancing your digestive system...
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- 6 time tested and proven strategies to improving your leaky gut syndrome with herbs...
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Now, in this accessible, comprehensive guide, one of the country’s leading
gastroenterologists, Dr. Cynthia Yoshida, provides the answers every woman needs, starting with a tour of the female GI system and the profound role sex hormones play. Brought to you by the American Gastroenterological Association, the book features the newest breakthrough medical treatments, plus advice on diet and gentle natural therapies that really work. No More Digestive Problems includes:
• Handling the effects of PMS, pregnancy, and menopause
• The surprising influence of weight on digestion—with vital information
on eating disorders
• Combating common ills from bloating, belching, and heartburn
to the runs and constipation
• Meeting the challenges of reflux (GERD), food intolerances, irritable bowel
syndrome (IBS), and inflammatory bowel disease (IBD)
• The crucial facts about women and colon cancer—and how to reduce your risk
Filled with revealing patient anecdotes, self-help tips, information on standard tests, and important questions you may want to ask your physician, here is an invaluable—and potentially lifesaving—resource for women of all ages.
From the Trade Paperback edition.
The Complete Low-FODMAP Diet (cowritten by Sue Shepherd) introduced this revolutionary treatment, which is rapidly becoming the first-line recommendation by doctors and dietitians worldwide. FODMAP is an acronym that stands for a group of difficult-to-digest carbohydrates found in foods such as wheat, milk, beans, soy, and some fruits, vegetables, nuts, and sweeteners. More than three quarters of adults with IBS who reduce their intake of these foods gain relief.
Now, this follow-up cookbook brings you 150 simple, delicious, and brand-new recipes that are full of flavor but low in FODMAPs. The mix includes:breakfasts to start the day off right (Blueberry Pancakes; Banana-Chocolate Chip Muffins)starters and sides for every occasion (Spring Rolls; Chicken, Bacon, and Pesto Mini Pizzas; Stuffed Roasted Bell Peppers)soups and salads full of flavor (Vietnamese Beef Noodle Salad; Creamy Seafood Soup)entrées that make you feel good (Chicken and Vegetable Curry; Speedy Spaghetti Bolognese; Beef Satay Stir-Fry with Peanut Sauce)desserts that satisfy (Flourless Chocolate Cake; Almond Cookies; Baked Blueberry Cheesecakes).The low-FODMAP diet puts an end to suffering in silence, fearing the possible consequences of every meal, or confining yourself to a handful of bland, “safe” foods. The only thing missing from this comprehensive collection is the FODMAPs—and you’d never know it!
Make optimal use of genetic testing to assess your patients’ risk of metabolic liver disease and to personalize treatment regimens for chronic hepatitis C.Offer your liver transplantation patients the best prognosis and follow-up with the latest information on outcomes and the management of complications.
Use blood test panels and noninvasive imaging techniques to evaluate the degree of liver fibrosis.
Make informed treatment decisions with the latest clinical trial results for portal hypertension, autoimmune liver diseases, acute liver failure, and hepatic infections.
Search the complete text online, download all the images, and test your knowledge with 200 board-style review questions at www.expertconsult.com.
Completely updated, this comprehensive medical resource offers a practical, problem-based approach to the subject of clinical gastroenterology.
Containing specialist content from Australian and international contributors, Clinical Gastroenterology, 3rd Edition focuses on both common and uncommon gastroenterological problems as they present in clinical practice.
Building on the previous two editions, Clinical Gastroenterology features decision trees to assist clinicians in assessing patients and the treating digestive disorders.
This latest edition also includes clear medical illustrations suitable for patient education, along with summary tables highlighting key points to guide General Practitioners, gastroenterology specialist trainees and medical students
New to this edition
• each chapter commences with a case study and contains key point summaries at the end
• new chapters on inflammatory bowel disease; obesity and anti-obesity surgery; principles of anaesthesia for endoscopy and preparing patients for endoscopy; complications of endoscopy; liver transplant and end-stage liver disease
• expanded sections on pancreatic masses and cysts, and radiological evaluation including the place of cross-sectional imaging
• gastroenterological case studies and key point summaries in each chapter
• new chapters on gastroenterological and hepatological medical conditions, including inflammatory bowel disease, obesity and anti-obesity surgery, principles of anaesthesia for endoscopy and preparing patients for endoscopy, complications of endoscopy, liver transplant and end-stage liver disease
• an expanded section on pancreatic cysts and masses
• an expanded section on radiological evaluation including the place of cross-sectional imaging
Whether it is asthma, food or pollen allergies, type-1 diabetes, lupus, multiple sclerosis, or Crohn’s disease, everyone knows someone who suffers from an allergic or autoimmune disorder. And if it appears that the prevalence of these maladies has increased recently, that’s because it has—to levels never before seen in human history. These days no fewer than one in five—and likely more—Americans suffers from one of these ailments. We seem newly, and bafflingly, vulnerable to immune system malfunction. Why? Science writer Moises Velasquez-Manoff explains the latest thinking about this problem and explores the remarkable new treatments in the works.
In the past 150 years, improved sanitation, water treatment, and the advent of vaccines and antibiotics have saved countless lives, nearly eradicating diseases that had plagued humanity for millennia. But now, a growing body of evidence suggests that the very steps we took to combat infections also eliminated organisms that kept our bodies in balance. The idea that we have systematically cleaned ourselves to illness challenges deeply entrenched notions about the value of societal hygiene and the harmful nature of microbes. Yet scientists investigating the rampant immune dysfunction in the developed world have inevitably arrived at this conclusion. To address this global “epidemic of absence,” they must restore the human ecosystem.
This groundbreaking book explores the promising but controversial “worm therapy”—deliberate infection with parasitic worms—in development to treat autoimmune disease. It explains why farmers’ children so rarely get hay fever, why allergy is less prevalent in former Eastern Bloc countries, and how one cancer-causing bacterium may be good for us. It probes the link between autism and a dysfunctional immune system. It investigates the newly apparent fetal origins of allergic disease—that a mother’s inflammatory response imprints on her unborn child, tipping the scales toward allergy. In the future, preventive treatment—something as simple as a probiotic—will necessarily begin before birth.
An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
An Epidemic of Absence considers the critical immune stimuli we inadvertently lost as we modernized, and the modern ills we may be able to correct by restoring them. At stake is nothing less than our health, and that of our loved ones. Researchers, meanwhile, have the good fortune of living through a paradigm shift, one of those occasional moments in the progress of science when a radically new way of thinking emerges, shakes things up, and suggests new avenues of treatment. You’ll discover that you’re not you at all, but a bustling collection of organisms, an ecosystem whose preservation and integrity require the utmost attention and care.
Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"— an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes—which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones—each custom-designed for maximum health benefits.
Characterize abdominal masses and adenopathywith the aid of diffusion-weighted MR imaging.
See how gastrointestinal conditions presentwith more than 2,500 multi-modality, high-quality digital images that mirror the findings you're likely to encounter in practice. Make optimal use of the latest abdominal and gastrointestinal imaging techniques with new chapters on diffusion weighted MRI, perfusion MDCT and MRI, CT colonography, CT enterography and MR enterography—sophisticated cross-sectional imaging techniques that have dramatically improved the utility of CT and MR for detecting a host of pathologic conditions in the gastrointestinal tract.
Expert guidanceis right at your fingertips. Now optimized for use on mobile devices, this edition is perfect as an on-the-go resource for all abdominal imaging needs.
Effectively apply MR and CT perfusion, diffusion weighted imaging, PET/CT and PET/MRin evaluating tumor response to therapy.
This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike.
New to this edition:
*Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves
*Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems
Over the past twenty years, thousands of physicians have come to depend on Yamada’s Textbook of Gastroenterology. Its encyclopaedic discussion of the basic science underlying gastrointestinal and liver diseases as well as the many diagnostic and therapeutic modalities available to the patients who suffer from them was—and still is—beyond compare. This new textbook, Principles of Clinical Gastroenterology, is designed to inform practitioners on the features of the major clinical disorders in gastroenterology and hepatology from the point of view of the clinician observing signs and symptoms of a patient under care and management.
It is a practical guide to diagnosis and decision making in clinical practice and provides a rich source of information on diseases of the gastrointestinal tract and liver. Covering the full range of examinations in gastroenterology and hepatology, with extremely timely chapters on patients with dyspepsia, eating disorders, jaundice, hepatitis, cirrhosis, and on screening, Principles of Clinical Gastroenterology gives you easy access to approaches that a clinician might take to common symptoms and signs presented by patients with such disorders. The chapters include the epidemiology, history, signs and symptoms, diagnosis, treatment, and prognosis of the most commonly encountered disorders in gastroenterology and hepatology.
This textbook will be an invaluable resource whether you are a gastroenterologist, internist, surgeon, or other clinician who sees patients with gastrointestinal and liver disorders. It should be kept close at hand for frequent consultation.
Fortunately for you, there's Schaum's Outlines. More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test your skills.
This Schaum's Outline gives you:Practice problems with full explanations that reinforce knowledge Coverage of the most up-to-date developments in your course field In-depth review of practices and applications
Fully compatible with your classroom text, Schaum's highlights all the important facts you need to know. Use Schaum's to shorten your study time-and get your best test scores!
Schaum's Outlines-Problem Solved.
Not impossible when you consider there is something equivalent to the size of a village football pitch hiding inside our bellies – that’s the incredible magnitude of our digestive systems. They contain an extensive network of nerve cells, called neurons, which carry information to the brain and thus have a profound effect upon our intellectual, emotional and immune processes.
Dr Matveikova answers the obvious questions: “How?” and “Why can this be so?” by explaining, in straight forward layman’s language, that the digestive system contains more than one million neurones, identical to those in the brain and is responsible for producing 90% of the body’s hormone, serotonin, the all-important hormone which makes us feel happy and full of wellbeing. It follows, that if our stomachs are “out of sorts” we can feel irritable, in a bad mood, lacking in energy and those feelings will block our intellectual productivity, tend to disorientate us and completely change our thought patterns and physical processes.
In The Fever, the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we've invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria's jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.
The 1st edition was sold out within one year and a reprint became necessary. The 2nd edition has been updated, revised and extended to include some 900 pages.
- 477 top-quality coloured figures containing clinical and immunological findings, laparoscopic and and histologic features as well as imaging procedures
- all figures directly integrated in the respective text; this results in a new form of learning from "seeing" to "understanding"
- 306 tables in colour
- coloured highlighting of important principles and statements for better reading
- well-structured and systematic approaches support the content
- derived from clinical hepatology for practical use by specialists and in hospital
- detailed presentation of morphology and its integration in liver disease
- precise recommendations for therapy and summarized descriptions of special forms of treatment (inlcuding a separate chapter on "Therapy"
- about 7,000 references are listed in full; quotations of significant historical publications
- first authors of therapy procedures, methods, medical techniques and invasive measures are given as far as possible
- comprehensive subject index and register of abbreviations
From the Trade Paperback edition.
The new fourth edition has been thoroughly revised and updated to reflect the many advances in science and technology, including the five accepted sequential stages of micropropagation. Ten new plants have been added. This in turn has greatly expanded the already extensive bibliography. Among the new topics that have been introduced or expanded on are embryo culture for breeding, somaclonal variation, anther culture, somatic embryogenesis, cryopreservation, and genetic engineering. More ornamental plant examples are given and many new illustrations provided, including a chronology of discoveries in micropropagation.
Following Mardell Hill’s simple formula, anyone can reduce their digestive disorder or pain symptoms by identifying their unique path to self-recovery. While some may seek medical care, others may try an alternative route; still others try to self-medicate, and yet many still suffer even after various treatments. Today people want effective, safe, and natural solutions for digestive health and care. Here, then, is a practical, easy-to-use guide that walks readers through the various issues they may confront, how to prevent them, and how to get relief should symptoms crop up.
Hill responds to some of the most commonly asked questions about preventing, or stopping, abdominal pain and discomfort. In clear and simple language, she helps readers better understand how digestion works, from top to bottom, and explores the many different difficulties that can arise along this path. Offering sound and proven advice, she helps readers feel better and live better.
Includes New and Updated Material
Now in its second edition, this work is the culmination of research and discussions with technical experts, as well as USP and FDA representatives on various topics of interest to the pharmaceutical microbiologist and those responsible for the microbial quality of products, materials, equipment, and manufacturing facilities. New in this edition is an entire chapter dedicated to the topic of biofilms and their impact on pharmaceutical and biopharmaceutical operations. The subject of rapid methods in microbiology has been expanded and includes a discussion on the validation of alternative microbiological methods and a case study on microbial identification in support of a product contamination investigation.
Substantially updated and revised, this book assists readers in understanding the fundamental issues associated with pharmaceutical microbiology and provides them with tools to create effective microbial contamination control and microbial testing programs for the areas under their responsibility.
Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.
Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.
The book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field.Provides an understanding of the theoretical principles important for biological NMR spectroscopyDemonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experimentsAllows for the capability of designing effective experimental protocols for investigations of protein structures and dynamicsIncludes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods
Get the essential gastroenterology information you needfrom one authoritative source with an outstanding global reputation for excellence.
Zero in on the key information you need to knowwith a consistent, full-color chapter design. Stay up to date with emerging and challenging topics: enteric microbiota and probiotics; fecal microbiota transplantation; Clostridium difficile colitis; and factitious gastrointestinal diseases.
Incorporate the latest findings and improvements in care for liver disease patients—from diagnosis and treatment through post-treatment strategies and management of complications.
Expert Consult eBook version included with purchase.This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Two patients—each known in medical history as the Berlin Patient—were cured of the HIV virus. The two patients’ disparate cures came twelve years apart, but Nathalia Holt, an award-winning scientist at the forefront of HIV research, connects the molecular dots of these cases for the first time.
Scientists are known to maintain a professional distance from those they study, but sometimes scientists are not just investigators, they are caregivers, too. Cured illustrates that even in the era of high-tech and big pharma, the way doctors and patients communicate remains a critical ingredient in the advance of this science. Holt offers a kind of hope that the thirty-four million people currently infected with HIV need and a story of ingenuity, dedication, and humanity that will inspire the rest of us.
* Only available work to cover the entire whisky process from raw material to delivery to the market in such a comprehensive manner
* Includes a chapter on marketing and selling whisky
* Foreword written by Alan Rutherford, former Chairman and Managing Director of United Malt and Grain Distillers Ltd.
The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.Contains the applications of pharmaceutical microbiology in sterile and non-sterile productsPresents the practical aspects of pharmaceutical microbiology testingProvides contamination control risks and remediation strategies, along with rapid microbiological methodsIncludes bioburden, endotoxin, and specific microbial risksHighlights relevant case studies and risk assessment scenarios
The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces this book presents a fresh, new approach to the teaching of immunology.
After an introduction to the basic structure of the immune system, the book looks at two important families of signalling molecules: cytokines and chemokines, before covering the workings of the mucosal immune system. It continues by examining immunity against the four major groups of pathogens - viruses, bacteria, fungi and parasites, and concludes by looking at disorders of the immune system, mucosal tumour immunology and the process of vaccination.A fresh, new approach to the subject focusing on mucosal and body surfaces. Describes the mucosal immune systems of the gastrointestinal, respiratory and urogenital tracts, as well as the skin. Details the important roles of cytokines and chemokines in an immune response. Separate chapters devoted to immunity against viruses, bacteria, fungi and parasites. Includes chapter summaries, boxes with topics of special interest and an extensive glossary. Clearly written and well- illustrated in full colour throughout.
Students across a range of disciplines, including biology, biochemistry, biomedicine, medicine and veterinary sciences, will find this book invaluable, both as an introduction to basic immunology and as a guide to mucosal immune defence mechanisms.
Unfortunately, this has not eradicated reflux disease. It has just changed its nature. While heartburn, ulceration and strictures have become rare, reflux-induced adenocarcinoma of the esophagus is becoming increasingly common. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world.
The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. GERD brings together a vast amount of disparate literature and presents the entire pathogenesis of reflux disease in one place. In addition to providing a new concept of how gastroesophageal reflux causes cellular changes in the esophagus, GERD also offers a complete solution to a problem that has confused physicians for over a century. Both clinical and pathological information about reflux disease and its treatment are presented. GERD is meant to be used as a comprehensive reference for gastroenterologists, esophageal surgeons, and pathologists alike.Outlines how gastroesophageal reflux causes cellular changes in the esophagusBrings together the pathogenesis of the disease in one source and applies it toward clinical treatmentTom DeMeester is THE leading international expert on reflux disease; Parakrama Chandrasoma is one of the leading pathologists in the areaBook contains approximately 350 illustrationsAncillary web site features color illustrations: www.chandrasoma.com