From the Trade Paperback edition.
-Drug therapy for behavioral and anxiety disorders
-Clinical practice guidelines for treating psychological disorders
-Depression and the action of antidepressant drugs
-The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders
-Drug therapy for children, adolescents and the elderly
-"New generation" antipsychotic agents
Authoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action is an indispensable source of information for anyone interested in drug use, abuse, and education.
Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs:
Drugs acting on inflammation
Drugs acting on respiratory system
Drugs acting on digestive system
Drugs acting on blood and blood-forming organs
Drugs acting on endocrine system
Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents
Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic
Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject
Covers the syllabi of majority of Indian universities
• Examines 414 psychoactive plants and related substances
• Explores how using psychoactive plants in a culturally sanctioned context can produce important insights into the nature of reality
• Contains 797 color photographs and 645 black-and-white illustrations
In the traditions of every culture, plants have been highly valued for their nourishing, healing, and transformative properties. The most powerful plants--those known to transport the human mind into other dimensions of consciousness--have traditionally been regarded as sacred. In The Encyclopedia of Psychoactive Plants Christian R䴳ch details the botany, history, distribution, cultivation, and preparation and dosage of more than 400 psychoactive plants. He discusses their ritual and medicinal usage, cultural artifacts made from these plants, and works of art that either represent or have been inspired by them. The author begins with 168 of the most well-known psychoactives--such as cannabis, datura, and papaver--then presents 133 lesser known substances as well as additional plants known as “legal highs,” plants known only from mythological contexts and literature, and plant products that include substances such as ayahuasca, incense, and soma. The text is lavishly illustrated with 797 color photographs--many of which are from the author’s extensive fieldwork around the world--showing the people, ceremonies, and art related to the ritual use of the world’s sacred psychoactives.
This is a detailed and practical guide to botulinum neurotoxin therapy (BoNT) and the wide range of applications for neurological and pain disorders. A unique reference source for new injectors and experienced clinicians alike, this indispensable manual provides information on dose, dilution, and indications for all four FDA-approved toxins in one handy text.
Following a brief review of relevant pharmacology, the book provides product information and comparative distinctions between the four FDA-approved toxins (BotoxÆ, MyoblocÆ, XeominÆ, and DysportÆ), along with indications and doses for FDA-approved conditions, guidance techniques, and common and emerging clinical applications. The heart of the book is an injection manual, organized anatomically and by condition and covering all applications for medical treatment. For each condition or site, information is provided on typical muscle pattern or muscle groups involved, dosing guidelines and dilution for the applicable toxins, number of injection sites, and potential risks and benefits. Targeting techniques are organized in table format for quick retrieval. Anatomic illustrations and cross-sections are provided to orient injectors and help identify optimal insertion points. An appendix with useful clinical rating scales is also included.Key Features:Presents state-of-the-art information about current indications for all four FDA-approved botulinum neurotoxinsCompares and contrasts the four toxins along with common and emerging clinical applicationsProvides dosing guidelines for various indications and injection sites for each muscleIncludes anatomic drawings and cross-sections to illustrate muscle relationships and insertion pointsServes as a practical, portable, how-to guide for new and experienced clinicians
This fully revised and updated eighth edition provides essential information on new medications and treatment options and includes the latest research on side effects, contraindications, and efficacy of all major medications prescribed for mental health disorders. The book also features an important new chapter on the effects of withdrawing from psychopharmacological medications.
This handbook makes it simple to: get the facts about drug interactions and side effects; find out how medications affect adults, children, and adolescents differently; learn how different cultures view medical treatment, vital information for anyone who treats clients from a variety of backgrounds; and discontinue medication safely when needed.
This essential guide to psychopharmacology has been adopted as a textbook at universities nationwide and is an important resource for every therapist’s library.
Illegal Drugs is the first comprehensive reference to offer timely, pertinent information on every drug currently prohibited by law in the United States. It includes their histories, chemical properties and effects, medical uses and recreational abuses, and associated health problems, as well as addiction and treatment information.
Additional survey chapters discuss general and historical information on illegal drug use, the effect of drugs on the brain, the war on drugs, drugs in the workplace, the economy and culture of illegal drugs, and information on thirty-three psychoactive drugs that are legal in the United States, from caffeine, alcohol and tobacco to betel nuts and kava kava.
One of the most important books written on the effects of LSD on the human psyche.
• Its authoritative research has great relevance to the current debate on drug legalization.
• Prolific authors Robert Masters and Jean Houston are pioneer figures in the field of transpersonal psychology and founders of the Human Potentials Movement.
The Varieties of Psychedelic Experience was published in 1966, just as the first legal restrictions on the use of psychedelic substances were being enacted. Unfortunately, the authors' pioneering work on the effects of LSD on the human psyche, which was viewed by its participants as possibly heralding a revolution in the study of the mind, was among the casualties of this interdiction. As a result, the promising results to which their studies attested were never fully explored. Nevertheless, their 15 years of research represents a sober and authoritative appraisal of what remains one of the most controversial developments in the study of the human psyche. Avoiding the wild excesses taken by both sides on this issue, this book is unique for the light it sheds on the possibilities and the limitations of psychedelic drugs, as well as on the techniques for working with them. With drug legalization an increasingly important issue, The Varieties of Psychedelic Experience provides a welcome and much needed contrast to the current hysteria that surrounds this topic.
Recent scandals involving diabetes drugs, Vioxx, and many other medications reveal the serious and undisclosed risks of some of the most commonly used prescription drugs in this country. In Before You Take That Pill, Dr. J. Douglas Bremner, a researcher and clinician at Emory University whose study on Accutane and depression made headlines, offers an inside look at the pharmaceutical industry, as well as a scientifically backed assessment of the risks of more than three hundred prescribed medications, vitamins, and supplements.
While many drugs are essential to the health of consumers, as Dr. Bremner explains, for many people, the benefits may not outweigh the potential side effects. This book contains warnings that are not on the drug labels. It also exposes tricks of the trade that demonstrate how the profit-making interests of "big pharma" may not always be in line with the safety of the public - from the corruption that exists in the drug approval process to the tactics drug companies use to encourage doctors to prescribe their products. Most important, Before You Take That Pill empowers readers by giving them sound information on specific medications so they can understand and weigh the potential risk themselves. Backed by the latest studies, as well as insight from a doctor who is in the trenches, this book should be on the shelf of every drug consumer.
'If we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again' David Cameron, Prime Minister
Resistance to our current range of antibiotics is the new inconvenient truth. If we don't act now, we risk the health of our parents, our children and our grandchildren.
Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food.
No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily.
This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall.
Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College.
Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics.
Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.
Psychiatrists have settled for treating symptoms rather than causes, embracing the apparent medical rigor of DSM diagnoses and prescription in place of learning the more challenging craft of therapeutic counseling, gaining only limited understanding of their patients’ lives. Talk therapy takes time, whereas the fifteen-minute "med check" allows for more patients and more insurance company reimbursement. Yet DSM diagnoses, he shows, are premised on a good deal less science than we would think.
Writing from an insider’s perspective, with refreshing forthrightness about his own daily struggles as a practitioner, Dr. Carlat shares a wealth of stories from his own practice and those of others that demonstrate the glaring shortcomings of the standard fifteen-minute patient visit. He also reveals the dangers of rampant diagnoses of bipolar disorder, ADHD, and other "popular" psychiatric disorders, and exposes the risks of the cocktails of medications so many patients are put on. Especially disturbing are the terrible consequences of overprescription of drugs to children of ever younger ages. Taking us on a tour of the world of pharmaceutical marketing, he also reveals the inner workings of collusion between psychiatrists and drug companies.
Concluding with a road map for exactly how the profession should be reformed, Unhinged is vital reading for all those in treatment or considering it, as well as a stirring call to action for the large community of psychiatrists themselves. As physicians and drug companies continue to work together in disquieting and harmful ways, and as diagnoses—and misdiagnoses—of mental disorders skyrocket, it’s essential that Dr. Carlat’s bold call for reform is heeded.
The American Diabetes Association Guide to Insulin & Type 2 Diabetes addresses common fears about insulin therapy and what is involved with beginning to use insulin. Additional chapters discuss fine-tuning of insulin self-management, gadgets to make life easier, and troubleshooting steps to overcome any problems readers may have.
Split into two sections, the first provides an alphabetised directory of the most common and effective natural plant supplements, with beautifully illustrated pictures of the plants in their natural form. The second section provides guidance on testing, individualised treatment, and self-usage of pharma-standard supplements, based on real-life experiments and human observations.
Through careful investigation of the existing market, specific criteria have been created to ensure only those supplements which have shown results are included. Additionally, as most supplements can be produced and used in countries where 'industrial' drug distribution is limited and costly, it gives people increased access to alternative medical treatment.
This project is currently the first of its kind, created to establish a new field of supplements defined by pharmaceutical standards. It is perfect for pharmacists, healthcare providers, and those interested in increasing their knowledge of new standards for natural remedies.
UPDATED ANNUALLY!Organized alphabetically by generic drug name Common uses, mechanisms of action, dosages (adult and pediatric), warnings/precautions, form supplied, and notes/common side effects Summaries of FDA "Black Box" precautions and contraindications Includes a listing of the medications organized by drug classification Covers natural and herbal agents Updated to reflect new drugs, removal of drugs taken off the market, new formulations, and changes in approved use of existing medications
Scientific information is presented in a clear, simple manner designed for students and general readers alike. In addition to the A-Z descriptions, Miller provides an explanation of general drug types, such as stimulants and hallucinogens, as well as the aspects of drug abuse, including tolerance and withdrawal. A list of print and electronic sources is also included for readers seeking further information.
Brain Candy is an authoritative, comprehensive, and above all, cutting-edge look at what you can take to rev up your brain—enhance memory, think faster, sharpen creativity, focus better. The only authors yet to tackle this subject who are experts in both brain function and drug action, Theodore Lidsky and Jay Schneider explain in plain English what the effects of these substances are on the body. For aging baby boomers—and for anyone else who wants a quicker wit—Brain Candy has all the answers.
The classic guide to all major prescription and nonprescription drugs, featuring revised, up to date FDA information and an A-Z list of illnesses for easy reference. Includes coverage of dosage and length of time before drug takes effect; side effects, special precautions; interactions with other food and drugs; standards for use by different age groups, and more.
The visual design of this manual aids the rapid retrieval of information and makes it possible to offer more information than the popular Sanford Guide, while focusing on the essentials and eliminating the extensive details covered in standard textbooks and online references. The Antibiotic Manual includes 188 of the most common agents used in internal medicine by drug name.
Manage any challenge in ocular toxicologywith extensive coverage of principles of therapy; ocular drug delivery; methods to evaluate drug-induced visual side effects; and the role of electrophysiology and psychophysics.
Benefit from the masterful guidance and global perspectiveof world authorities in the field who provide need-to-know information on all aspects of ocular toxicology—all in one concise reference.
Confer with the WHO classification systemto determine whether a particular side effect is certain, probable, or likely to occur.
Zero in on the key information you need to knowwith highly templated, concise chapters. Apply the latest knowledge and treatments for newly recognized Adverse Drug Reactions (ADR). Identify which ADR’s are clinically relevant and what to do about them.
Experience clinical scenarioswith vivid clarity through a wealth of new and updated clinical photographs that provide unmatched, visual diagnostic guidance.
Recognize and avoid drug-induced ocular side effectswith data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden).
Stay up to date and provide state-of-the-art carewith the latest information on approved medications.
-- Norman Rosenthal, M.D., author of St. John's Wort: The Herbal Way to Feeling Good
* Restore the vital vitamins, minerals, and hormones necessary to maintain good health.
* Optimize your body's metabolic system.
* Restore your ability to experience pleasure in life.
An estimated twenty-five million Americans take antidepressants to combat depression, but most continue to cope with a host of debilitating side effects that equal, and sometimes outweigh, the medication's obvious benefits. Many doctors consider side effects such as weight gain, lethargy, and sexual dysfunction to be necessary evils. Finally, there is a doctor who refuses to trade a patient's total well-being for the treatment of depression.
Clinical psychiatrist Robert J. Hedaya, M.D., has developed a comprehensive mind-body program to restore lost vitality and sex drive and control weight. A Washington Post bestseller in hardcover, his book offers a proven program of nutrition, exercise, stress reduction, and hormone supplementation that not only lessens the side effects of antidepressants but enhances their benefits as well. Now everyone can benefit from the prescription that has worked wonders for his own patients.
From the Trade Paperback edition.
Discover how Africa’s traditional healers play a critical role in treating diseases such as HIV and AIDS. In developing countries with poor infrastructure, these healers are located in nearly every rural village setting as well as in the busy urban areas. While underappreciated, they may play a key role in solving the continent’s diverse health problems.
ò Therapeutic function
ò Chemical and common name
ò Structural Formula
ò Chemical Abstracts Registry no.
ò Trade name, manufacturer, country, and year introduced
ò Raw Materials
ò Manufacturing Process
In addition, references are also cited under each drug's entry to major pharmaceutical works where additional information can be obtained on synthesis and the pharmacology of the individual products.
Each diagnosis includes appropriate drug choices listed alphabetically by generic name and Trade name, FDA pregnancy category, drug availability in generic or over-the-counter forms, adult and pediatric dosing regimens, brand names, dosage forms, drug additives, and more. Thirty easy-to-use tables in the appendices include FDA pregnancy categories, U.S. Schedule of Controlled Substances, Childhood and Adult Immunization Schedules, Contraceptive Guidance, categories of Glucocorticosteroids, Anti-infectives by class, and more. An alphabetical cross-reference index of drugs by generic and brand name, with FDA pregnancy category and controlled drug schedule, facilitates quick identification of drugs by alternate names, and relative safety during pregnancy.
Facilitates speedy drug information retrieval for primary care providers in all settings
Organizes over 300 diagnoses alphabetically by alternate names for ease of use
Highlights clinically important information such as lab values to monitor, patient education points, and safety information
Includes Appendix of 30 tables for quick access to key drug classifications, FDA pregnancy categories, Schedule of Controlled Substances, Childhood and Adult Immunization Schedules, etc.
Provides generic/Trade name cross reference reference
the context of alcohol and drug misuse, and the nature and theories of addiction, including a historical overview and policy initiatives in contemporary society
an overview of the problems associated with psychoactive substances and their impact on groups such as black and minority ethnic people, young people, women, older people and the homeless
an understanding of the generic role responses to substance misuse in a variety of different settings and contexts, including primary care, community and hospitals
a framework for assessment, care planning, harm reduction approach, dealing with overdose, intoxication and withdrawals, psychological and pharmacological interventions
an accessible and skills-oriented approach to assist students and practitioners in dealing with drug and alcohol misuse.
Alcohol and Drug Misuse takes into account current policy initiatives and practice for substance use and misuse and includes a range of pedagogical features to enhance learning. It is essential reading for nursing and health students taking substance misuse modules, as well as related CPD courses for health care professionals.
In recent years, the media have inundated us with coverage of the horrors that befall methamphetamine users, and the fires, explosions, and toxic waste created by meth labs that threaten the well-being of innocent people. In Methamphetamine: Its History, Pharmacology, and Treatment, the first book in Hazelden's Library of Addictive Drugs series, Ralph Weisheit and William L. White examine the nature and extent of meth use in the United States, from meth's early reputation as a "wonder drug" to the current perception that it is a "scourge" of society.In separating fact from fiction, Weisheit and White provide context for understanding the meth problem by tracing its history and the varying patterns of use over time, then offer an in-depth look at:the latest scientific findings on the drug's effects on individualsthe myths and realities of the drug's impact on the mindthe national and international implications of methamphetamine productionthe drug's impact on rural communities, including a case study of two counties in the Midwestissues in addiction and treatment of meth.Thoroughly researched and highly readable, Methamphetamine offers a comprehensive understanding of medical, social, and political issues concerning this highly impactful drug.Written for professionals and serious lay readers by nationally recognized experts, the books in the Library of Addictive Drugs series feature in-depth, comprehensive, and up-to-date information on the most commonly abused mood-altering substances.
While the number of patients using medical marijuana increases every year, misconceptions about cannabis and whether it’s harmful or dangerous still exist. In Cannabis for Chronic Pain, Dr. Rav explains the potential of marijuana’s capacity for healing anyone afflicted with chronic pain. Medical marijuana is a safe, non-addictive alternative to dangerous opiate pain pills.
Along with sharing his own story of using medical marijuana to heal from a severe case of shingles, Dr. Rav guides you through the cannabis and holistic treatment for your specific chronic pain condition. If you are suffering from arthritis, back pain, migraines, fibromyalgia, menstrual cramps, IBS, Crohn’s Disease, anxiety, depression, or pain from cancer or its treatment, this may be the book for you.
Dr. Rav offers step by step instruction on the benefits and appropriate use of medical marijuana. And he dispels many of the misconceptions. Did you know that you don’t have to smoke or eat cannabis for it to be effective? There are now patches and drops. We are entering a new age of acceptance and perhaps most importantly, as Dr. Rav highlights, it is now possible to create a distinct cannabis prescription for different types of chronic pain. Find what works for you and finally get the relief you need.
Cannabis for Chronic Pain is the new, definitive guide for anyone who suffers from chronic pain.
After dealing with the general considerations of drug phenomena and quantum theory, this book goes on exploring the various molecular orbital calculation methods and the significance of molecular orbital indices. The subsequent chapters on the applications of molecular orbital theory are organized on the basis of physical chemical phenomena concluded from the studies described to be involved in the biological activity. These chapters also look into the correlations between indices reflecting covalent bond formation and biological activity. This text further examines the charge transfer mechanisms of several drug classes. The remaining chapters are devoted to the use of molecular orbital theory in several aspects of drug research, including molecular conformation, acid-base phenomena, hydrogen bonding, and dispersion forces.
This work is directed to the advanced undergraduate or graduate students in medicinal chemistry or pharmacology, as well as to the practicing scientists interested in acquiring some understanding of molecular orbital theory. Theoretical chemists seeking information on biological phenomena amenable to semiempirical molecular orbital study will find this book invaluable.
Each test method is reported together with (1) a data example from practice, (2) all steps to be taken using a scientific pocket calculator, and (3) the main results and their interpretation. Although several of the described methods can also be carried out with the help of statistical software, the latter procedure will be considerably slower.
Both part 1 and 2 of this title consist of a minimum of text and this will enhance the process of mastering the methods. Yet the authors recommend that for a better understanding of the test procedures the books be used together with the same authors' textbook "Statistics Applied to Clinical Studies" 5th edition edited 2012, by Springer Dordrecht Netherlands. More complex data files like data files with multiple treatment modalities or multiple predictor variables can not be analyzed with a pocket calculator. We recommend that the small books "SPSS for starters", Part 1 and 2 (Springer, Dordrecht, 2010, and 2012) from the same authors be used as a complementary help for the readers' benefit.
This massive update has numerous new drugs, diseases, vaccines, and syndromes. It also contains new tables, and changes to hundreds of existing drugs.
Written by a world-renown clinical pharmacologist, Dr. Thomas Hale, and Clinical Pharmacy Specialist Dr. Hilary Rowe, this drug reference provides the most comprehensive review of the data available regarding the transfer of various medications into human milk.
This new and expanded reference has data on 1,115 drugs, vaccines, and herbals, with many other drugs and substances included in the appendices.
New to this Edition:Many new drugs, vaccines, herbals, and chemicals.Major updates to existing drug monographs.New tables to compare and contrast the suitability of psychiatric medications.New table to compare and contrast pain medications.Updated table and new monograph on hormonal contraception.
If you work with breastfeeding mothers, this book is an essential tool to use in your practice.
The book has six sections:
Section Ideals with the physicochemical principles. Two new chapters: Complexations and ICH Guidelines for Stability Testing, have been added to make it more informative.
Section IIconveys the information regarding pharmaceutical unit operations and processes.
Section IIIdescribes the area of pharmaceutical practice. Extensive recent updates have been included in many chapters of this section. Two new chapters: Parenteral Formulations and New Drug Delivery Systems, have been added.
Section IVcontains radioactivity principles and applications.
Section Vdeals with microbiology and animal products.
Section VIcontains the formulation and packaging aspects of pharmaceuticals. Pilot Plant Manufacturing concepts are added as a new chapter, which may be beneficial to readers to understand the art of designing of a plant from the pilot plant model.
The authors of the volume are distinguished scientists who are leading experts in the field, and who have contributed important, original data to our understanding of the mechanisms of appetite control. They have quite different scientific backgrounds and, together, they represent all relevant disciplines. Thereby, the topics are presented from different points of view, not exclusively from that of pharmacology and neuroendocrinology. Thus, the volume addresses all scientists who are interested in the field of obesity research and the pathophysiology of appetite control.