Ebola, SARS, Hendra, AIDS, and countless other deadly viruses all have one thing in common: the bugs that transmit these diseases all originate in wild animals and pass to humans by a process called spillover. In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?
Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are.
The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people.
Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. It will change both our view of nature and our sense of where we belong in it.
Microbiology is a fascinating field that explores life down to the tiniest level. Did you know that your body contains more bacteria cells than human cells? It's true. Microbes are essential to our everyday lives, from the food we eat to the very internal systems that keep us alive. These microbes include bacteria, algae, fungi, viruses, and nematodes. Without microbes, life on Earth would not survive. It's amazing to think that all life is so dependent on these microscopic creatures, but their impact on our future is even more astonishing. Microbes are the tools that allow us to engineer hardier crops, create better medicines, and fuel our technology in sustainable ways. Microbes may just help us save the world.
Microbiology For Dummies is your guide to understanding the fundamentals of this enormously-encompassing field. Whether your career plans include microbiology or another science or health specialty, you need to understand life at the cellular level before you can understand anything on the macro scale.Explore the difference between prokaryotic and eukaryotic cells Understand the basics of cell function and metabolism Discover the differences between pathogenic and symbiotic relationships Study the mechanisms that keep different organisms active and alive
You need to know how cells work, how they get nutrients, and how they die. You need to know the effects different microbes have on different systems, and how certain microbes are integral to ecosystem health. Microbes are literally the foundation of all life, and they are everywhere. Microbiology For Dummies will help you understand them, appreciate them, and use them.
Updates reflect current changes to the fourth edition of ECGs Made Easy.UPDATED content and illustrations reflect changes to ECGs Made Easy, 5th Edition.
Provides a full understanding of the ECG in the diagnosis and management of abnormal cardiac rhythms.
Emphasises the role of the full 12 lead ECG with realistic reproduction of recordings.
The unique page size allows presentation of all 12-lead ECGs across a single page for clarity.Restructured into two clear sections, the first ‘The Basics’ explains the ECG in the simplest possible terms.
The new second section, ‘Making the most of the ECG’, has separate chapters on the ECG patterns that might be seen in healthy subjects and in patients presenting with chest pain, breathlessness, palpitations or syncope.
Whether it is asthma, food or pollen allergies, type-1 diabetes, lupus, multiple sclerosis, or Crohn’s disease, everyone knows someone who suffers from an allergic or autoimmune disorder. And if it appears that the prevalence of these maladies has increased recently, that’s because it has—to levels never before seen in human history. These days no fewer than one in five—and likely more—Americans suffers from one of these ailments. We seem newly, and bafflingly, vulnerable to immune system malfunction. Why? Science writer Moises Velasquez-Manoff explains the latest thinking about this problem and explores the remarkable new treatments in the works.
In the past 150 years, improved sanitation, water treatment, and the advent of vaccines and antibiotics have saved countless lives, nearly eradicating diseases that had plagued humanity for millennia. But now, a growing body of evidence suggests that the very steps we took to combat infections also eliminated organisms that kept our bodies in balance. The idea that we have systematically cleaned ourselves to illness challenges deeply entrenched notions about the value of societal hygiene and the harmful nature of microbes. Yet scientists investigating the rampant immune dysfunction in the developed world have inevitably arrived at this conclusion. To address this global “epidemic of absence,” they must restore the human ecosystem.
This groundbreaking book explores the promising but controversial “worm therapy”—deliberate infection with parasitic worms—in development to treat autoimmune disease. It explains why farmers’ children so rarely get hay fever, why allergy is less prevalent in former Eastern Bloc countries, and how one cancer-causing bacterium may be good for us. It probes the link between autism and a dysfunctional immune system. It investigates the newly apparent fetal origins of allergic disease—that a mother’s inflammatory response imprints on her unborn child, tipping the scales toward allergy. In the future, preventive treatment—something as simple as a probiotic—will necessarily begin before birth.
An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
An Epidemic of Absence considers the critical immune stimuli we inadvertently lost as we modernized, and the modern ills we may be able to correct by restoring them. At stake is nothing less than our health, and that of our loved ones. Researchers, meanwhile, have the good fortune of living through a paradigm shift, one of those occasional moments in the progress of science when a radically new way of thinking emerges, shakes things up, and suggests new avenues of treatment. You’ll discover that you’re not you at all, but a bustling collection of organisms, an ecosystem whose preservation and integrity require the utmost attention and care.
The easily referenced outline format allows health practitioners of all levels to understand and apply basic concepts to patient care--perfect for cardiothoracic and general surgery residents, physician assistants, nurse practitioners, cardiologists, medical students, and critical care nurses involved in the care of both routine and complex cardiac surgery patients.
This comprehensive guide features:Detailed presentation addressing all aspects of perioperative care for adult cardiac surgery patients Outline format allowing quick access to information Chronological approach to patient care starting with diagnostic tests then covering preoperative, intraoperative, and postoperative care issues Additional chapters discuss bleeding, the respiratory, cardiac, and renal subsystems as well as aspects of care specific to recovery on the postoperative floor Updated references, information on new drug indications and new evidence to support various treatment/management options.
Practical and accessible, this new edition of Manual of Perioperative Care in Adult Cardiac Surgery is the essential reference guide to cardiac surgical patient care.
Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"— an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes—which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones—each custom-designed for maximum health benefits.
In this groundbreaking book, Dr. Kilmer S. McCully explains what is really behind the epidemic of heart disease. For many years, clogged arteries have been inaccurately viewed as the cause, rather than a symptom, of heart disease. Now, McCully shows you how to cut your risk of heart disease by controlling the real culprit, homocysteine. Considered one of the most significant medical breakthroughs in recent years, McCully's findings have been validated by numerous large-scale studies. The Heart Revolution:
Challenges the long-held assumption that lowering cholesterol is the key to preventing heart disease
Explains how eating vitamin B-rich food can control homocysteine levels
Lays out a plan with menus for putting more B vitamins in our diet
Discusses how food processing and additives compromise our health
Explains how costly cholesterol-lowering medicines can actually harm our health
Eat Your Way to a Healthy Heart
Pork Chops with Potatoes and Onions, Veal with Wine and Mushrooms, Guacamole, Omelettes. This is not your typical diet program. Dr. McCully offers real food choices with fresh ingredients available just about everywhere. The focus is on delicious foods that will leave you satisfied. The purpose is to make sure you're getting enough of the vitamins needed to prevent heart disease—B6, B12, and folic acid, as well as essential, phytochemicals, fat-soluble vitamins, minerals, antioxidants, and essential oils. It's easy to follow this plan as it relies on foods you want to eat with little preparation time and tons of variety.
A companion Website will include the fully searchable text, an image bank, an interactive question bank, and an EKG image with explanation test bank.
Fortunately for you, there's Schaum's Outlines. More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test your skills.
This Schaum's Outline gives you:Practice problems with full explanations that reinforce knowledge Coverage of the most up-to-date developments in your course field In-depth review of practices and applications
Fully compatible with your classroom text, Schaum's highlights all the important facts you need to know. Use Schaum's to shorten your study time-and get your best test scores!
Schaum's Outlines-Problem Solved.
In The Fever, the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we've invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria's jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.
From the Trade Paperback edition.
In this text, the user will learn the basic anatomy of an EKG waveform as it relates to the cardiac rhythm cycle. It provides step-by-step instruction from the initial to the final wave with simple, easy to read and understand rhythm strip examples.
Included are charts, tables, templates and other references to assist the user in the quick and accurate interpretation of EKG's.
Heart disease kills more people than any other medical condition,
and no one is more aware of this than renowned cardiologist Dr. Chauncey
Crandall. In addition to having performed over 40,000 heart procedures during
his career, Dr. Crandall has experienced this deadly disease on the most
personal level — as a patient.
At the age of 48, and with no major risk factors, he found himself
in the ER with a blockage of his main coronary artery. After emergency
intervention, he recovered from heart disease using the same course of
treatment he recommends to his thousands of patients, making him living proof
of his program’s success.
In his new book, The Simple
Heart Cure: The 90-Day Program to Stop and Reverse Heart Disease, you’ll
find this top doc’s groundbreaking, three-pronged approach to prevent and
reverse heart disease — an approach honed by his study of cultures free of
heart disease, and his decades of experience helping thousands of patients
achieve a healthier heart at any age.
So if you’re recovering from a heart attack or concerned with
preventive maintenance, you’ll find the help you need in The Simple Heart Cure, including
great, heart-healthy menus, and a 90-day, week-by-week plan to help you start
taking action immediately.
are just a few of the potentially life-saving gems you’ll discover in The
Simple Heart Cure: The 90-Day Program to Stop and Reverse Heart Disease:
How to slash your risk of a deadly heart
attack by 61%... Proven ways to banish your “bad” cholesterol… 8 easy steps to head off high blood pressure… How you can safeguard against lethal stroke…
Simple strategies to unclog your arteries — without
surgery… What your belly says about your heart health… Must-have heart tests for every person over
50… Easy solutions to steer clear of statin drugs… Special advice for women, diabetics, the
very stressed, and much more…
“By following the advice in Dr.
Chauncey Crandall’s new book The Simple Heart Cure, you can
surmount the biggest challenge of all and win your battle against heart
— Scott Carpenter, Astronaut, NASA’s Mercury
When it comes to your heart health, The Simple Heart Cure
could be the most important book you’ll ever read!
This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike.
New to this edition:
*Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves
*Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems
Stem Cell Research For Dummies offers a balanced, plain-English look at this politically charged topic, cutting away the hype and presenting the facts clearly for you, free from debate. It explains what stem cells are and what they do, the legalities of harvesting them and using them in research, the latest research findings from the U.S. and abroad, and the prospects for medical stem cell therapies in the short and long term.Explains the differences between adult stem cells and embryonic/umbilical cord stem cells Provides both sides of the political debate and the pros and cons of each side's opinions Includes medical success stories using stem cell therapy and its promise for the future
Comprehensive and unbiased, Stem Cell Research For Dummies is the only guide you need to understand this volatile issue.
Includes New and Updated Material
Now in its second edition, this work is the culmination of research and discussions with technical experts, as well as USP and FDA representatives on various topics of interest to the pharmaceutical microbiologist and those responsible for the microbial quality of products, materials, equipment, and manufacturing facilities. New in this edition is an entire chapter dedicated to the topic of biofilms and their impact on pharmaceutical and biopharmaceutical operations. The subject of rapid methods in microbiology has been expanded and includes a discussion on the validation of alternative microbiological methods and a case study on microbial identification in support of a product contamination investigation.
Substantially updated and revised, this book assists readers in understanding the fundamental issues associated with pharmaceutical microbiology and provides them with tools to create effective microbial contamination control and microbial testing programs for the areas under their responsibility.
Chapter objectives preview the main points in each chapter.
Stop and Review sections at the end of the chapters help you remember the most important information.
ACLS Pearls boxes offer key points and useful tips for clinical practice.
Keeping it Simple boxes provide essential information in a clear and concise manner.
Ten case studies present real-life clinical situations, allowing you to make decisions based on information in the Preparatory section.
Consistent format of case studies includes Objective, Skills to Master, Rhythms to Master, Medications to Master, Related Text Chapters, Essential Actions, and Unacceptable Actions.
A heart rate ruler is included to help you interpret ECGs.
4 x 6 pocket-size quick-reference card contains key ACLS algorithms for field use.100 new and updated photos and illustrations show key ACLS procedures and equipment. Pharmacological interventions are integrated into the chapters for a more cohesive learning experience. New streamlined approach reduces the number of pages and simplifies the information you need to know.
Experience with clinical cases is key to mastering the art and science of medicine and ultimately to providing patients with competent clinical care. Case Files: Cardiology provides 30 real-life cases that illustrate essential concepts in cardiac care. Each case includes an easy-to-understand discussion correlated to key concepts, definitions of key terms, clinical pearls, and board-style review questions to reinforce your learning. With Case Files, you'll learn instead of memorize.Learn from 30 high-yield cases, each with board-style questions Master key concepts with clinical pearls Sharpen your clinical problem-solving and patient care skills
The new fourth edition has been thoroughly revised and updated to reflect the many advances in science and technology, including the five accepted sequential stages of micropropagation. Ten new plants have been added. This in turn has greatly expanded the already extensive bibliography. Among the new topics that have been introduced or expanded on are embryo culture for breeding, somaclonal variation, anther culture, somatic embryogenesis, cryopreservation, and genetic engineering. More ornamental plant examples are given and many new illustrations provided, including a chronology of discoveries in micropropagation.
Here, Dr. Mann, a nationally recognized hypertension specialist, identifies the drugs most likely to have side effects, and those that can be used in their place. He describes the shortcomings of some of the new drugs, while also introducing readers to some excellent old drugs that are woefully underused as a result of the publicity blitz surrounding the new, expensive ones. He emphasizes the importance of matching the medication and dosage to the individual who will be taking them, and presents the overlooked clues that can tell us who should be on which drug (even an excellent drug can be the wrong one if it is given to the wrong person or in the wrong dose). Hypertension and You is directed at the more than 50 million Americans (including a majority of people over the age of 60) who are taking blood pressure medication. Many patients suspect they might be on the wrong medication, but don’t know enough to be sure. This book shows how medications can be prescribed more wisely to achieve better results and gives patients the knowledge they need to capably discuss their medications with their health care providers.
Hypertension and You provides many ideas and approaches that will be new to readers, and also to many physicians, and which no other book offers. It’s the first book to make the case that something is terribly wrong with how doctors are prescribing drugs for this condition. It provides readers with better knowledge of the available medications, empowering them to work with their physician to get onto the medications that are right for them.
Review a full range of ECG images - from simple to complex - reflecting both common and rare conditions.
Get the most from your board or certification prep by pairing this review with its parent text, Cardiac Electrophysiology: From Cell to Bedside, for detailed explanations and an enhanced learning experience.
Unique Flip and See section at the end of the book allows you to see each rhythm side-by-side with a normal ECG rhythm, while a written walkthrough explains the important differences between the rhythms.
Excuse Me! features highlight frequently asked student questions with easy-to-understand answers. Conversational language and clear illustrations and cartoons make the information easy to remember and fun to learn.New and updated information across the entire book includes coverage of new pacemaker strips and now includes 12-lead interpretation and 12-lead axis identification.
New cartoons have been added to make key points memorable and entertaining.
Updated algorithms reflect the new 2010 ECC Guidelines.
Completely redesigned Cohn's Pocket Guide for ECG Interpretation, a plastic heart rate ruler, aids both students and practitioners in rhythm interpretation. Expanded appendix provides illustrations of ECG complexes as they relate to heart damage.
Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation?
Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences.
Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe.
Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.
– Winner, Stephen Hawking Medal for Science Communication
Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before.
In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility.
Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging.
Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell’s ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body’s trillions of cells.
But some of our cells don’t age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young.
The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade.
The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.
Access the fully searchable contents onlineat www.expertconsult.com, in addition to downloadable images and dynamic video clips.
Fully understand the rationale for treatment of specific arrhythmiaswith practical techniques that are grounded in the most recent basic science. Stay up to date with new chapters on molecular mechanisms of cardiac electrical activity, cardiac ion channels, ventricular tachycardia in nonischemic dilated cardiomyopathy, epicardial ventricular tachycardia, ventricular arrhythmias in hypertrophic cardiomyopathy, ventricular arrhythmias in inherited channelopathies, ventricular arrhythmias in congenital heart disease, atrial arrhythmias in congenital heart disease, and complications of catheter ablation of cardiac arrhythmias.
View videos of 27 key techniques online, including optical mapping of reentrant ventricular arrhythmias, 3-dimensional mapping of arrhythmias using different mapping and navigation modalities, and fluoroscopy images illustrating techniques for electrophysiologic catheter positioning, atrial septal puncture, and pericardial access.
Gain a new understanding of hot topicssuch as mechanisms of arrhythmias, electrophysiologic testing, mapping and navigation modalities, ablation energy sources, sinus node dysfunction, conduction disturbances, atrial tachyarrhythmias, preexcitation syndromes and all types of ventricular and supraventricular tachycardias.
The easily referenced outline format allows health practitioners of all levels to understand and apply basic concepts to patient care—perfect for cardiothoracic and general surgery residents, physician assistants, nurse practitioners, cardiologists, medical students, and critical care nurses involved in the care of both routine and complex cardiac surgery patients.
This comprehensive guide features:
Detailed presentation addressing all aspects of perioperative care for adult cardiac surgery patients
Outline format allowing quick access to information
Chronological approach to patient care starting with diagnostic tests then covering preoperative, intraoperative, and postoperative care issues
Additional chapters discussing bleeding, the respiratory, cardiac, and renal subsystems in depth, and aspects of care specific to recovery on the postoperative floor
Completely updated references
Extensive illustrations, including NEW figures depicting operative techniques
14 helpful appendices covering order and flow sheets, protocols, commonly used drug dosages, and procedures
Practical and accessible, the Manual of Perioperative Care in Adult Cardiac Surgery is the essential reference guide to cardiac surgical patient care.
-- from the Introduction
If you are interested in a better way to treat heart failure, this book is for you. Dr. Michael McIvor – who has taught thousands of healthcare professionals how to effectively care for patients with chronic HF through CME symposia – takes a logical, step-by-step approach to setting up and operating the kind of program that reduces hospital admissions and improves patient care.
Establishing a Heart Failure Program: The Essential Guide answers the different questions posed by physicians, nurse practitioners, nurses, and hospital administrators, all of whom need to work as a team to achieve success. The three major sections of the book address:
Taking the first steps toward building your heart failure program - developing a business plan, choosing your model of care, and making accurate financial projections
Assembling the pieces of your program – managers, front line staff, and the physical facility
A companion website presents forms you can download and use in your own heart failure center. Drawing from experience, Dr. McIvor helps you avoid common problems by identifying potential problems and sharing advice that has proven effective to your colleagues. He gives you the essential tools – unavailable elsewhere – to set up and maintain a heart failure program that achieves superior clinical outcomes.
Apply dependable clinical advice from Marschall S. Runge, MD, PhD, Cam Patterson, MD and George Stouffer, MD and utilize diagnostic and therapeutic algorithms and clinical pathways developed by the many world-renowned chapter contributors.Utilize annotated references to the most important resources and evidence-based studies.
Benefit from expanded coverage of cardiovascular imaging including echocardiography, stress testing and nuclear imaging, and CT and MRI.
* Only available work to cover the entire whisky process from raw material to delivery to the market in such a comprehensive manner
* Includes a chapter on marketing and selling whisky
* Foreword written by Alan Rutherford, former Chairman and Managing Director of United Malt and Grain Distillers Ltd.
Several of the cases incorporate chest X-rays and coronary angiograms illustrating the appearances that are associated with various cardiac conditions.
All the cases are graded in difficulty and are cross-referenced to the new editions of ECG Made Easy and ECG in Practice for further information.
For this Fourth Edition over 30 new ECGs have been included, mainly to provide clearer examples, though the book deliberately retains some technically poor records to maintain a ’real-world’ perspective.
Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.
Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.
The book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field.Provides an understanding of the theoretical principles important for biological NMR spectroscopyDemonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experimentsAllows for the capability of designing effective experimental protocols for investigations of protein structures and dynamicsIncludes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods
In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction.
When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection.
This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.
Are you one of the eighty-two million Americans currently diagnosed with cardiovascular disease—or one of the millions more who think they are healthy but are at risk? Whether your goal is to get the best treatment or stay out of the cardiologist’s office, your heart's health depends upon accurate information and correct answers to key questions. In Heart 411, two renowned experts, heart surgeon Marc Gillinov and cardiologist Steven Nissen, tackle the questions their patients have raised over their decades of practice: Can the stress of my job really lead to a heart attack? How does exercise help my heart, and what is the right amount and type of exercise? What are the most important tests for my heart, and when do I need them? How do symptoms and treatments differ among men, women, and children?
Backed by decades of clinical experience and up-to-the-minute research, yet written in the accessible, down-to-earth tone of your trusted family doctor, Heart 411 cuts through the confusion to give you the knowledge and tools you need to live a long and heart-healthy life.
From the Trade Paperback edition.
An essential guide for daily clinical practice and a thorough review for the cardiothoracic boards, Johns Hopkins Textbook of Cardiothoracic Surgery is filled with authoritative guidance on surgical techniques and pre- and postoperative strategies for managing cardiothoracic disease. The content of this trusted classic reflects the rapidly changing field of cardiothoracic surgery. In addition to the basic curriculum required for certification, you will find coverage of advanced concepts, controversial issues, and new technologies.
Johns Hopkins Textbook of Cardiothoracic Surgery provides an in-depth look at the full-spectrum of disorders and their surgical and medical management options, including congenital, acquired, and neoplastic diseases. Supporting this detailed coverage is an easy-to-navigate design and step-by-step explanations of the most complex operations.
THE SECOND EDITION IS HIGHLIGHTED BY:NEW board review Q&A Ten NEW chapters including:
Surgical Therapies for Atrial Fibrillation, Management of Adults with Congenital Heart Disease, and Stem Cells for Cardiac Surgical Disease NEW full-color illustrations An increased number of decision-making flow charts that will prove valuable when preparing for cases and examinations Key Concepts that highlight epidemiology, pathophysiology, clinical features, diagnostic and treatment strategies, and outcomes for each topic
NOTE: This book was previously known as the Johns Hopkins Manual of Cardiothoracic Surgery but the second edition has been renamed to better reflect its scope and comprehensive nature.
Join them in The Manga Guide to Molecular Biology, and learn all about DNA, RNA, proteins, amino acids, and more. Along the way, you'll see chemical reactions first-hand and meet entertaining characters like Enzyme Man and Drinkzilla, who show how the liver metabolizes alcohol.
Together with Ami and Rin, you'll learn all about:
* The organelles and proteins inside cells, and how they support cellular functions
* The processes of transcription and translation, and your genes' role in synthesizing proteins
* The pieces that make up our genetic code, like nucleotides, codons, introns, and exons
* The processes of DNA replication, mitosis and cytokinesis
* Genetic technology like transduction and cloning, and the role of molecular biology in medicine
Whether you need a molecular biology refresher or you're just fascinated by the science of life, The Manga Guide to Molecular Biology will give you a uniquely fun and informative introduction.
Easily remedy weak areas in your knowledge by reviewing details for each question, plus cross references to Braunwald’s for more in-depth explanations.
Enhance your preparation for the boards by reviewing case studies in all sections of the text.Get a realistic simulation of the exam experience with interactive review questions at www.expertconsult.com.
Assess your mastery of the latest topics in cardiovascular medicine, including molecular cardiovascular imaging, intravascular ultrasound imaging, cardiovascular regeneration and tissue engineering, device therapy for advanced heart failure, atrial fibrillation management, structural heart disease, and Chagasic heart disease.
Maximize your comprehension with full-color images and illustrations throughout the text.
The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.Contains the applications of pharmaceutical microbiology in sterile and non-sterile productsPresents the practical aspects of pharmaceutical microbiology testingProvides contamination control risks and remediation strategies, along with rapid microbiological methodsIncludes bioburden, endotoxin, and specific microbial risksHighlights relevant case studies and risk assessment scenarios
In The South Beach Heart Program, Dr. Arthur Agatston's innovative approach to heart disease prevention will show you how to protect your heart and live a longer, healthier life. He not only explains how to assess your cardiac risks and avoid unneccessary surgery, but also teaches you how to make life-saving changes, including rethinking your eating and exercise habits, to beat the odds of suffering from cardiovascular disease.
Dr. Agatston explains:How you can have a negative stress test and still be at risk for a heart attackWhy your cholesterol level may not accurately indicate your risk for heart attackHow a simple noninvasive heart scan can reveal if you are a cardiac time bombWhy belly fat can be deadly--and what you can do about itWhat you need to know about life-saving state-of-the-art blood testing, heart imaging, medications, and moreHow to transform your lifestyle with satisfying heart-healthy eating and an exercise program that's easy to integrate into your daily routine
The South Beach Heart Program will change the way you treat your health, your heart, and your approach to living well.