The million copy international bestseller, critically acclaimed and translated into over 25 languages. This 30th anniversary edition includes a new introduction from the author as well as the original prefaces and foreword, and extracts from early reviews. As relevant and influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology community, generating much debate and stimulating whole new areas of research.

“The bard of biological weapons captures
the drama of the front lines.”
-Richard Danzig, former secretary of the navy


The first major bioterror event in the United States-the anthrax attacks in October 2001-was a clarion call for scientists who work with “hot” agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.

Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.

Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.

Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.

From New York Times bestselling author Sam Kean comes incredible stories of science, history, language, and music, as told by our own DNA.

In The Disappearing Spoon, bestselling author Sam Kean unlocked the mysteries of the periodic table. In THE VIOLINIST'S THUMB, he explores the wonders of the magical building block of life: DNA.

There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists.

Kean's vibrant storytelling once again makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

"Dr. Gundry has crafted a wise program with a powerful track record.”
–Mehmet Oz, M.D.

Does losing weight and staying healthy feel like a battle? Well, it’s really a war. Your enemies are your own genes, backed by millions of years of evolution, and the only way to win is to outsmart them. Renowned surgeon and founder of Gundry MD, Dr. Steven Gundry’s revolutionary book shares the health secrets other doctors won’t tell you:

• Why plants are “good” for you because they’re “bad” for you, and meat is “bad” because it’s “good” for you
• Why plateauing on this diet is actually a sign that you’re on the right track
• Why artificial sweeteners have the same effects as sugar on your health and your waistline
• Why taking antacids, statins, and drugs for high blood pressure and arthritis masks health issues instead of addressing them

Along with the meal planner, 70 delicious recipes, and inspirational stories, Dr. Gundry’s easy-to-memorize tips will keep you healthy and on course.

The million copy international bestseller, critically acclaimed and translated into over 25 languages. As influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology community, generating much debate and stimulating whole new areas of research. Forty years later, its insights remain as relevant today as on the day it was published. This 40th anniversary edition includes a new epilogue from the author discussing the continuing relevance of these ideas in evolutionary biology today, as well as the original prefaces and foreword, and extracts from early reviews. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

Since Dr. Brizendine wrote The Female Brain ten years ago, the response has been overwhelming. This New York Times bestseller has been translated into more than thirty languages, has sold nearly a million copies between editions, and has most recently inspired a romantic comedy starring Whitney Cummings and Sofia Vergara. And its profound scientific understanding of the nature and experience of the female brain continues to guide women as they pass through life stages, to help men better understand the girls and women in their lives, and to illuminate the delicate emotional machinery of a love relationship.



Every brain begins as a female brain. It only becomes male eight weeks after conception, when excess testosterone shrinks the communications center, reduces the hearing cortex, and makes the part of the brain that processes sex twice as large.

Louann Brizendine, M.D. is a pioneering neuropsychiatrist who brings together the latest findings to show how the unique structure of the female brain determines how women think, what they value, how they communicate, and whom they’ll love. Brizendine reveals the neurological explanations behind why

• A woman remembers fights that a man insists never happened

• A teen girl is so obsessed with her looks and talking on the phone

• Thoughts about sex enter a woman’s brain once every couple of days but enter a man’s brain about once every minute

• A woman knows what people are feeling, while a man can’t spot an emotion unless somebody cries or threatens bodily harm

• A woman over 50 is more likely to initiate divorce than a man

Women will come away from this book knowing that they have a lean, mean communicating machine. Men will develop a serious case of brain envy.

The genome's been mapped.
But what does it mean?

Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life.

Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

The million copy international bestseller, critically acclaimed and translated into over 25 languages. As influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology community, generating much debate and stimulating whole new areas of research. Forty years later, its insights remain as relevant today as on the day it was published. This 40th anniversary edition includes a new epilogue from the author discussing the continuing relevance of these ideas in evolutionary biology today, as well as the original prefaces and foreword, and extracts from early reviews. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

By the best selling author of The Selfish Gene 'This entertaining and thought-provoking book is an excellent illustration of why the study of evolution is in such an exciting ferment these days.' Science 'The Extended Phenotype is a sequel to The Selfish Gene . . . he writes so clearly it could be understood by anyone prepared to make the effort' John Maynard Smith, London Review of Books 'Dawkins is quite incapable of being boring this characteristically brilliant and stimulating book is original and provocative throughout, and immensely enjoyable.' G. A. Parker, Heredity 'The extended phenotype is certainly a big idea and it is pressed hard in dramatic language.' Sydney Brenner, Nature 'Richard Dawkins, our most radical Darwinian thinker, is also our best science writer.' Douglas Adams 'Dawkins is a superb communicator. His books are some of the best books ever written on science.' Megan Tressider, Guardian 'Dawkins is a genius of science popularization.' Mark Ridley, The Times

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story
 

Fewer ideas have been more toxic or harmful than the idea of the biological reality of race, and with it the idea that humans of different races are biologically different from one another. For this understandable reason, the idea has been banished from polite academic conversation. Arguing that race is more than just a social construct can get a scholar run out of town, or at least off campus, on a rail. Human evolution, the consensus view insists, ended in prehistory.

Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years—to be lactose tolerant, for example, and to survive at high altitudes. Race is not a bright-line distinction; by definition it means that the more human populations are kept apart, the more they evolve their own distinct traits under the selective pressure known as Darwinian evolution. For many thousands of years, most human populations stayed where they were and grew distinct, not just in outward appearance but in deeper senses as well.

Wade, the longtime journalist covering genetic advances for The New York Times, draws widely on the work of scientists who have made crucial breakthroughs in establishing the reality of recent human evolution. The most provocative claims in this book involve the genetic basis of human social habits. What we might call middle-class social traits—thrift, docility, nonviolence—have been slowly but surely inculcated genetically within agrarian societies, Wade argues. These “values” obviously had a strong cultural component, but Wade points to evidence that agrarian societies evolved away from hunter-gatherer societies in some crucial respects. Also controversial are his findings regarding the genetic basis of traits we associate with intelligence, such as literacy and numeracy, in certain ethnic populations, including the Chinese and Ashkenazi Jews.

Wade believes deeply in the fundamental equality of all human peoples. He also believes that science is best served by pursuing the truth without fear, and if his mission to arrive at a coherent summa of what the new genetic science does and does not tell us about race and human history leads straight into a minefield, then so be it. This will not be the last word on the subject, but it will begin a powerful and overdue conversation.

From the Trade Paperback edition.

Virus of the Mind is the first popular book devoted to the science of memetics, a controversial new field that transcends psychology, biology, anthropology, and cognitive science. Memetics is the science of memes, the invisible but very real DNA of human society. In Virus of the Mind, Richard Brodie carefully builds on the work of scientists Richard Dawkins, Douglas Hofstadter, Daniel Dennett, and others who have become fascinated with memes and their potential impact on our lives. But Richard goes beyond science and dives into the meat of the issue: is the emergence of this new science going to have an impact on our lives like the emergence of atomic physics did in the Cold War? He would say the impact will be at least as great. While atomic bombs affect everybody's life, viruses of the mind touch lives in a more personal and more pernicious way. Mind viruses have already infected governments, educational systems, and inner cities, leading to some of the most pervasive and troublesome problems of society today: youth gangs, the welfare cycle, the deterioration of the public schools, and ever'growing government bureaucracy. Viruses of the mind are not a future worry: they are here with us now and are evolving to become better and better at their job of infecting us. The recent explosion of mass media and the information superhighway has made the earth a prime breeding ground for viruses of the mind. Will there be a mental plague? Will only some of us survive with our free will intact? Richard Brodie weaves together science, ethics, and current events as he raises these and other very disturbing questions about memes.

Written by two of the country's top genealogists, this authoritative book is the first to explain how new and groundbreaking genetic testing can help you research your ancestry.

According to American Demographics, 113 million Americans have begun to trace their roots, making genealogy the second most popular hobby in the country (after gardening). Enthusiasts clamor for new information from dozens of subscription-based websites, email newsletters, and magazines devoted to the subject. For these eager roots-seekers looking to take their searches to the next level, DNA testing is the answer.

After a brief introduction to genealogy and genetics fundamentals, the authors explain the types of available testing, what kind of information the tests can provide, how to interpret the results, and how the tests work (it doesn't involve digging up your dead relatives). It's in expensive, easy to do, and the results are accurate: It's as simple as swabbing the inside of your cheek and popping a sample in the mail.

There are several types of genealogical scenarios you can pursue, such as:Family lore has it that a branch of our family emigrated to Argentina and now I've found some people there with our name. Can testing tell us whether we're from the same family?My mother was adopted and doesn't know her ethnicity. Are there any tests available to help her learn about her heritage?I just discovered someone else with my highly unusual surname. How can we find out if we have a common ancestor?

The authors reveal exactly what is--and what is not--possible with genetic testing. They include case studies of both famous historial mysteries and examples of ordinary folks whose exploration of genetic genealogy has enabled them to trace their roots.

"Dazzling...A feast. Absorbing and elegantly written, it tells of theorigins of life on earth, describes its variety and charaacter, and culminates in a discussion of human nature and teh complex traces ofhumankind's evolutionary past...It is an amazing story masterfully told."
FINANCIAL TIMES (LONDON)
World renowned scientist Carl Sagan and acclaimed author Ann Druyan have written a ROOTS for the human species, a lucid and riveting account of how humans got to be the way we are. It shows with humor and drama that many of our key traits--self-awareness, technology, family ties, submission to authority, hatred for those a little different from ourselves, reason, and ethics--are rooted in the deep past, and illuminated by our kinship with other animals. Astonishing in its scope, brilliant in its insights, and an absolutely compelling read, SHADOWS OF FORGOTTEN ANCESTORS is a triumph of popular science.


From the Trade Paperback edition.

Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same.

Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it.

The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences," leads the reader through unexplored jungles and uncharted aspects of mind to the heart of knowledge.In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.

“We are the primary drivers of change. We will directly and indirectly determine what lives, what dies, where, and when. We are in a different phase of evolution; the future of life is now in our hands.”

Why are rates of conditions like autism, asthma, obesity, and allergies exploding at an unprecedented pace? Why are humans living longer, getting smarter, and having far fewer kids? How might your lifestyle affect your unborn children and grandchildren? How will gene-editing technologies like CRISPR steer the course of human evolution? If Darwin were alive today, how would he explain this new world? Could our progeny eventually become a different species—or several?

In Evolving Ourselves, futurist Juan Enriquez and scientist Steve Gullans conduct a sweeping tour of how humans are changing the course of evolution—sometimes intentionally, sometimes not. For example:

   •  Globally, rates of obesity in humans nearly doubled between 1980 and 2014. What’s more, there’s evidence that other species, from pasture-fed horses to lab animals to house cats, are also getting fatter.
   •  As reported by U.S. government agencies, the rate of autism rose by 131 percent from 2001 to 2010, an increase that cannot be attributed simply to increases in diagnosis rates.
   •  Three hundred years ago, almost no one with a serious nut allergy lived long enough to reproduce. Today, despite an environment in which food allergies have increased by 50 percent in just over a decade, 17 million Americans who suffer from food allergies survive, thrive, and pass their genes and behaviors on to the next generation.
   •  In the pre-Twinkie era, early humans had quite healthy mouths. As we began cooking, bathing, and using antibiotics, the bacteria in our bodies changed dramatically and became far less diverse. Today the consequences are evident not only in our teeth but throughout our bodies and minds. 

Though these harbingers of change are deeply unsettling, the authors argue that we are also in an epoch of tremendous opportunity. New advances in biotechnology help us mitigate the cruel forces of natural selection, from saving prematurely born babies to gene therapies for sickle cell anemia and other conditions. As technology like CRISPR enables us to take control of our genes, we will be able to alter our own species and many others—a good thing, given that our eventual survival will require space travel and colonization, enabled by a fundamental redesign of our bodies.

Future humans could become great caretakers of the planet, as well as a more diverse, more resilient, gentler, and more intelligent species—but only if we make the right choices now.

Intelligent, provocative, and optimistic, Evolving Ourselves is the ultimate guide to the next phase of life on Earth.

From the Hardcover edition.

In 1962, Maurice Wilkins, Francis Crick, and James Watson received the Nobel Prize, but it was Rosalind Franklin's data and photographs of DNA that led to their discovery.

Brenda Maddox tells a powerful story of a remarkably single-minded, forthright, and tempestuous young woman who, at the age of fifteen, decided she was going to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.

Human genetics has blossomed from an obscure branch of biological science and occasional explanation for exceedingly rare disorders to a field all of its own that affects everyone. Human Genetics: The Basics introduces the key questions and issues in this emerging field, including:

The common ancestry of all humanity

The role of genes in sickness and health

Debates over the use of genetic technology

Written in an engaging, narrative manner, this concise introduction is an ideal starting point for anyone who wants to know more about genes, DNA, and the genetic ties that bind us all.

A groundbreaking book about how your personality type determines who you love

Why do you fall in love with one person rather than another? In this fascinating and informative book, Helen Fisher, one of the world's leading experts on romantic love, unlocks the hidden code of desire and attachment. Each of us, it turns out, primarily expresses one of four broad personality types—Explorer, Builder, Director, or Negotiator—and each of these types is governed by different chemical systems in the brain. Driven by this biology, we are attracted to partners who both mirror and complement our own personality type.

Until now the search for love has been blind, but Fisher pulls back the curtain and reveals how we unconsciously go about finding the right match. Drawing on her unique study of 40,000 men and women, she explores each personality type in detail and shows you how to identify your own type. Then she explains why some types match up well, whereas others are problematic. (Note to Explorers: be prepared for a wild ride when you hitch your star to a fellow Explorer!) Ultimately, Fisher's investigation into the complex nature of romance and attachment leads to astonishing new insights into the essence of dating, love, and marriage.

Based on entirely new research—including a detailed questionnaire completed by seven million people in thirty-three countries—Why Him? Why Her? will change your understanding of why you love him (or her) and help you use nature's chemistry to find and keep your life partner.

Bill Gates recently told Wired that if he were a teenager today, he would be hacking biology. "If you want to change the world in some big way," he says, "that's where you should start-biological molecules."

The most disruptive force on the planet resides in DNA. Biotech companies and academic researchers are just beginning to unlock the potential of piecing together life from scratch. Champions of synthetic biology believe that turning genetic code into Lego-like blocks to build never-before-seen organisms could solve the thorniest challenges in medicine, energy, and environmental protection. But as the hackers who cracked open the potential of the personal computer and the Internet proved, the most revolutionary discoveries often emerge from out-of-the-way places, forged by brilliant outsiders with few resources besides boundless energy and great ideas.

In Biopunk, Marcus Wohlsen chronicles a growing community of DIY scientists working outside the walls of corporations and universities who are committed to democratizing DNA the way the Internet did information. The "biohacking" movement, now in its early, heady days, aims to unleash an outbreak of genetically modified innovation by making the tools and techniques of biotechnology accessible to everyone. Borrowing their idealism from the worlds of open-source software, artisinal food, Internet startups, and the Peace Corps, biopunks are devoted advocates for open-sourcing the basic code of life. They believe in the power of individuals with access to DNA to solve the world's biggest problems.

You'll meet a new breed of hackers who aren't afraid to get their hands wet, from entrepreneurs who aim to bring DNA-based medical tools to the poorest of the poor to a curious tinkerer who believes a tub of yogurt and a jellyfish gene could protect the world's food supply. These biohackers include:

-A duo who started a cancer drug company in their kitchen
-A team who built an open-source DNA copy machine
-A woman who developed a genetic test in her apartment for a deadly disease that had stricken her family

Along with the potential of citizen science to bring about disruptive change, Wohlsen explores the risks of DIY bioterrorism, the possibility of genetic engineering experiments gone awry, and whether the ability to design life from scratch on a laptop might come sooner than we think.

Author Dawson Church applies the insights of the new field of Epigenetics (epi=above, i.e. control above the level of the gene) to healing. Citing hundreds of scientific studies, he shows how beliefs and emotions can trigger the expression of DNA strands. He focuses on a class of genes called Immediate Early Genes or IEGs. These genes turn on within a few seconds of a stimulus. They can be triggered by thoughts or emotions ("I loved that unexpected gift of roses Bill gave me" or "I'm so mad about what Uncle John said at the Christmas party"). Many IEGs are regulatory genes turn on other genes that affect specific aspects of our immune system, such as the production of white blood cells that destroy attacking bacteria and viruses. Epigenetics thus influences our health every day.He coins the new term "Epigenetic Medicine" to describe healing techniques with epigenetic effects. He also summarizes the science behind the infant fields of Energy Psychology and Energy Medicine, both of which offer promising epigenetic medical therapies.

“Venter instills awe for biology as it is, and as it might become in our hands.” —Publishers Weekly

On May 20, 2010, headlines around the world announced one of the most extraordinary accomplishments in modern science: the creation of the world’s first synthetic lifeform. In Life at the Speed of Light, scientist J. Craig Venter, best known for sequencing the human genome, shares the dramatic account of how he led a team of researchers in this pioneering effort in synthetic genomics—and how that work will have a profound impact on our existence in the years to come. This is a fascinating and authoritative study that provides readers an opportunity to ponder afresh the age-old question “What is life?” at the dawn of a new era of biological engineering.

An “invaluable [and] highly readable” account of the quest to map our DNA, the blueprint for life—and what it means for our future ( The Philadelphia Inquirer).

Genome tells the story of the most ambitious scientific adventure of our time. By gradually isolating and identifying all the genes in the human body—the blueprint for life—scientists are closing in on the ability to effectively treat and prevent nearly every disease that strikes man, from muscular dystrophy, diabetes, and cancer to heart ailments, alcoholism, and even mental illness.
 
Such discoveries will change the course of human life. At the same time, they raise profound ethical questions that have tremendous implications: Can insurance companies demand genetic tests to determine who poses a health risk? Should parents be able to choose their baby’s sex or eye color? Will employers screen out potential employees who are genetically susceptible to occupational health problems?
 
An exciting true tale of discovery that is revolutionizing our world, Genome helps us understand our future.

A timely and gripping history of the controversial eugenics movement in America–and the scientists, social reformers and progressives who supported it.In Better for All the World, Harry Bruinius charts the little known history of eugenics in America–a movement that began in the early twentieth century and resulted in the forced sterilization of more than 65,000 people. Bruinius tells the stories of Emma and Carrie Buck, two women trapped in poverty who became the test case in the 1927 supreme court decision allowing forced sterilization for those deemed unfit to procreate. From the reformers who turned local charities into government-run welfare systems promoting social and moral purity, to the influence the American policies had on Nazi Germany’s development of “racial hygiene,” Bruinius masterfully exposes the players and legislation behind one of America’s darkest secrets.


From the Trade Paperback edition.

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?

Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.

Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

Nicholas Wade’s articles are a major reason why the science section has become the most popular, nationwide, in the New York Times. In his groundbreaking Before the Dawn, Wade reveals humanity’s origins as never before—a journey made possible only recently by genetic science, whose incredible findings have answered such questions as: What was the first human language like? How large were the first societies, and how warlike were they? When did our ancestors first leave Africa, and by what route did they leave? By eloquently solving these and numerous other mysteries, Wade offers nothing less than a uniquely complete retelling of a story that began 500 centuries ago.

The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Imagine that we had some way to look directly at the molecules in a living organism. An x-ray microscope would do the trick, or since we’re dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.

The Higgs Boson: Searching for the God Particle by the Editors of Scientific American

Updated 2017 Edition! For the fifth anniversary of one of the biggest discoveries in physics, we’ve updated this eBook to include our continuing analysis of the discovery, of the questions it answers and those it raises. As the old adage goes, where there’s smoke, there’s fire. Where there is effect, there must be cause. The planet Neptune was found in 1846 because the mathematics of Newton's laws, when applied to the orbit of Uranus, said some massive body had to be there. Astronomers eventually found it, using the best telescopes available to peer into the sky. This same logic is applied to the search for the Higgs boson. One consequence of the prevailing theory of physics, called the Standard Model, is that there has to be some field that gives particles their particular masses. With that there has to be a corresponding particle, made by creating waves in the field, and this is the Higgs boson, the so-called God particle. This eBook chronicles the search – and demonstrates the power of a good theory. Based on the Standard Model, physicists believed something had to be there, but it wasn't until the Large Hadron Collider was built that anyone could see evidence of the Higgs – and finally in July 2012, they did. A Higgs-like particle was found near the energies scientists expected to find it. Now, armed with better evidence and better questions, the scientific process continues. This eBook gathers the best reporting and analysis from Scientific American to explain that process – the theories, the search, the ongoing questions. In essence, everything you need to know to separate Higgs from hype.

This book serves as a reference for engineers, scientists, and students concerned with the use of materials in applications where reliability and resistance to corrosion are important. It updates the coverage of its predecessor, including coverage of: corrosion rates of steel in major river systems and atmospheric corrosion rates, the corrosion behavior of materials such as weathering steels and newer stainless alloys, and the corrosion behavior and engineering approaches to corrosion control for nonmetallic materials.

New chapters include: high-temperature oxidation of metals and alloys, nanomaterials, and dental materials, anodic protection. Also featured are chapters dealing with standards for corrosion testing, microbiological corrosion, and electrochemical noise.

You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony.

Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.

In this riveting, shocking, and beautifully written book, biologist Alanna Collen draws on the latest scientific research to show how our personal colony of microbes influences our weight, our immune system, our mental health, and even our choice of partner. She argues that so many of our modern diseases—obesity, autism, mental illness, digestive disorders, allergies, autoimmunity afflictions, and even cancer—have their root in our failure to cherish our most fundamental and enduring relationship: that with our personal colony of microbes.

Many of the questions about modern diseases left unanswered by the Human Genome Project are illuminated by this new science. And the good news is that unlike our human cells, we can change our microbes for the better. Collen's book is a revelatory and indispensable guide. It is science writing at its most relevant: life—and your body—will never seem the same again.

Now that DNA testing for genealogical purposes has existed for nearly a decade and a half—and been refined and improved during that time—it has established its value among family history researchers. It is now becoming accepted as another tool in the kit of well-rounded genealogists. This book covers this fast-growing application of genetics, empowering genealogists to apply this information to further their research. It will also enable general readers to understand how genetic information can be applied to verify or refute documentary research—and to break down frustrating walls that block the discovery of ancestors.

The book describes the three major categories of DNA testing for family history research: Y-chromosome tests for investigating paternal (surname) lines, mitochondrial tests for investigating maternal (umbilical) lines, and autosomal tests for exploring close relationships. Expert genealogist David Dowell provides guidance on deciding which test to take and identifying which members of your family should be tested to answer your most important genealogical questions. Readers will also learn how to interpret the results of tests and methods for further analysis to get additional value from them.

“Bold and provocative… Regenesis tells of recent advances that may soon yield endless supplies of renewable energy, increased longevity and the return of long-extinct species.”—New Scientist

In Regenesis, Harvard biologist George Church and science writer Ed Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

For 65 million years dinosaurs ruled the Earth--until a deadly asteroid forced their extinction. But what accounts for the incredible longevity of dinosaurs? A renowned scientist now provides a startling explanation that is rewriting the history of the Age of Dinosaurs. Dinosaurs were pretty amazing creatures--real-life monsters that have the power to fascinate us. And their fiery Hollywood ending only serves to make the story that much more dramatic. But fossil evidence demonstrates that dinosaurs survived several mass extinctions, and were seemingly unaffected by catastrophes that decimated most other life on Earth. What could explain their uncanny ability to endure through the ages? Biologist and earth scientist Peter Ward now accounts for the remarkable indestructibility of dinosaurs by connecting their unusual respiration system with their ability to adapt to Earth's changing environment--a system that was ultimately bequeathed to their descendants, birds. By tracing the evolutionary path back through time and carefully connecting the dots from birds to dinosaurs, Ward describes the unique form of breathing shared by these two distant relatives and demonstrates how this simple but remarkable characteristic provides the elusive explanation to a question that has thus far stumped scientists. Nothing short of revolutionary in its bold presentation of an astonishing theory, Out of Thin Air is a story of science at the edge of discovery. Ward is an outstanding guide to the process of scientific detection. Audacious and innovative in his thinking, meticulous and thoroughly detailed in his research, only a scientist of his caliber is capable of telling this surprising story.

News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.

Nuclear Energy is one of the most popular texts ever published on basic nuclear physics, systems, and applications of nuclear energy. This newest edition continues the tradition of offering a holistic treatment of everything the undergraduate engineering student needs to know in a clear and accessible way. The book presents a comprehensive overview of radioactivity, radiation protection, nuclear reactors, waste disposal, and nuclear medicine.

The seventh edition is restructured into three parts: Basic Concepts, Nuclear Power (including new chapters on nuclear power plants and introduction to reactor theory), and Radiation and Its Uses. Part Two in particular has been updated with current developments, including a new section on Reactor Safety and Security (with a discussion of the Fukushima Diiachi accident); updated information on naval and space propulsion; and revised and updated information on radioactive waste storage, transportation, and disposal. Part Three features new content on biological effects of radiation, radiation standards, and radiation detection.

Coverage of energy economics integrated into appropriate chaptersMore worked examples and end of chapter exercisesUpdated final chapter on nuclear explosions for current geopolitical developments

The definitive resource for electroplating, now completely up to date

With advances in information-age technologies, the field of electroplating has seen dramatic growth in the decade since the previous edition of Modern Electroplating was published. This expanded new edition addresses these developments, providing a comprehensive, one-stop reference to the latest methods and applications of electroplating of metals, alloys, semiconductors, and conductive polymers.

With special emphasis on electroplating and electrochemical plating in nanotechnologies, data storage, and medical applications, the Fifth Edition boasts vast amounts of new and revised material, unmatched in breadth and depth by any other book on the subject. It includes:

Easily accessible, self-contained contributions by over thirty experts

Five completely new chapters and hundreds of additional pages

A cutting-edge look at applications in nanoelectronics

Coverage of the formation of nanoclusters and quantum dots using scanning tunneling microscopy (STM)

An important discussion of the physical properties of metal thin films

Chapters devoted to methods, tools, control, and environmental issues

And much more

A must-have for anyone in electroplating, including technicians, platers, plating researchers, and metal finishers, Modern Electroplating, Fifth Edition is also an excellent reference for electrical engineers and researchers in the automotive, data storage, and medical industries.

Learn classical thermodynamics alongside statistical mechanics with this fresh approach to the subjects. Molecular and macroscopic principles are explained in an integrated, side-by-side manner to give students a deep, intuitive understanding of thermodynamics and equip them to tackle future research topics that focus on the nanoscale. Entropy is introduced from the get-go, providing a clear explanation of how the classical laws connect to the molecular principles, and closing the gap between the atomic world and thermodynamics. Notation is streamlined throughout, with a focus on general concepts and simple models, for building basic physical intuition and gaining confidence in problem analysis and model development. Well over 400 guided end-of-chapter problems are included, addressing conceptual, fundamental, and applied skill sets. Numerous worked examples are also provided together with handy shaded boxes to emphasize key concepts, making this the complete teaching package for students in chemical engineering and the chemical sciences.

Vegan, low fat, low carb, slow carb: Every diet seems to promise a one-size-fits-all solution to health. But they ignore the diversity of human genes and how they interact with what we eat.
In Food, Genes, and Culture, renowned ethnobotanist Gary Nabhan shows why the perfect diet for one person could be disastrous for another. If your ancestors were herders in Northern Europe, milk might well provide you with important nutrients, whereas if you're Native American, you have a higher likelihood of lactose intolerance. If your roots lie in the Greek islands, the acclaimed Mediterranean diet might save your heart; if not, all that olive oil could just give you stomach cramps.
Nabhan traces food traditions around the world, from Bali to Mexico, uncovering the links between ancestry and individual responses to food. The implications go well beyond personal taste. Today's widespread mismatch between diet and genes is leading to serious health conditions, including a dramatic growth over the last 50 years in auto-immune and inflammatory diseases.
Readers will not only learn why diabetes is running rampant among indigenous peoples and heart disease has risen among those of northern European descent, but may find the path to their own perfect diet.

The authors of the New York Times bestseller Super Brain present a bold new understanding of our genes and how simple changes in lifestyle can boost genetic activity. The leap into "radical well-being" is a promise waiting to be fulfilled.  
    
 "You are not simply the sum total of the genes you were born with," writes Deepak Chopra and Rudy Tanzi. "You are the user and controller of your genes, the author of your biological story. No prospect in self-care is more exciting."
 
Learning how to shape your gene activity is at the heart of this exciting and eagerly-anticipated book from the bestselling duo behind Super Brain, which became a nationwide hit on public television.  

For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago.  The impact on prevention, immunity, diet, aging, and chronic disorders is unparalleled.

Chemistry for grades 9 to 12 is designed to aid in the review and practice of chemistry topics. Chemistry covers topics such as metrics and measurements, matter, atomic structure, bonds, compounds, chemical equations, molarity, and acids and bases. The book includes realistic diagrams and engaging activities to support practice in all areas of chemistry. The 100+ Series science books span grades 5 to 12. The activities in each book reinforce essential science skill practice in the areas of life science, physical science, and earth science. The books include engaging, grade-appropriate activities and clear thumbnail answer keys. Each book has 128 pages and 100 pages (or more) of reproducible content to help students review and reinforce essential skills in individual science topics. The series will be aligned to current science standards.

Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject. The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

Decisive biotechnological interventions in the lottery of human life--to enhance our bodies and brains and perhaps irreversibly change our genetic makeup--have been widely rejected as unethical and undesirable, and have often met with extreme hostility. But in Enhancing Evolution, leading bioethicist John Harris dismantles objections to genetic engineering, stem-cell research, designer babies, and cloning to make a forthright, sweeping, and rigorous ethical case for using biotechnology to improve human life.

Human enhancement, Harris argues, is a good thing--good morally, good for individuals, good as social policy, and good for a genetic heritage that needs serious improvement. Enhancing Evolution defends biotechnological interventions that could allow us to live longer, healthier, and even happier lives by, for example, providing us with immunity from cancer and HIV/AIDS. But the book advocates far more than therapies designed to free us from sickness and disability. Harris champions the possibility of influencing the very course of evolution to give us increased mental and physical powers--from reasoning, concentration, and memory to strength, stamina, and reaction speed. Indeed, he supports enhancing ourselves in almost any way we desire. And it's not only morally defensible to enhance ourselves, Harris says. In some cases, it's morally obligatory.

Whether one looks upon biotechnology with hope, fear, or a little of both, Enhancing Evolution makes a case for it that no one can ignore.

The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise.

So we've all heard of genes, but how do they actually work?

There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. Figuring out how it all works – how your genes build your body – is a major challenge for researchers around the world. And what they're discovering is that far from genes being a fixed, deterministic blueprint, things are much more random and wobbly than anyone expected.

Drawing on stories ranging from six toed cats and stickleback hips to Mickey Mouse mice and zombie genes – told by researchers working at the cutting edge of genetics – Kat Arney explores the mysteries in our genomes with clarity, flair and wit, creating a companion reader to the book of life itself.

Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

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Genetically modified organisms (GMOs) including plants and the foods made from them, are a hot topic of debate today, but soon related technology could go much further and literally change what it means to be human. Scientists are on the verge of being able to create people who are GMOs.

Should they do it? Could we become a healthier and ''better'' species or might eugenics go viral leading to a real, new world of genetic dystopia? GMO Sapiens tackles such questions by taking a fresh look at the cutting-edge biotech discoveries that have made genetically modified people possible.

Bioengineering, genomics, synthetic biology, and stem cells are changing sci-fi into reality before our eyes. This book will capture your imagination with its clear, approachable writing style. It will draw you into the fascinating discussion of the life-changing science of human genetic modification.

Contents:An Introduction to Playing GodThe Birth and Explosive Growth of GMOsHuman CloningBuild-a-Baby Better via GeneticsDIY Guide to Creating GMO SapiensEugenics and TranshumanismCultural Views on Human Genetic ModificationGMO Sapiens Today and Tomorrow
Readership: Undergraduate biology majors, graduate biology majors, non-experts interested in GMOs, biologists and teenagers interested in cloning and human genetic modification.
Key Features:Books on this hot new topic of creating GMO people are rare, tend to be out-of-date, or have narrow topic rangesThe goal of this book is to educate and entertain an educated lay audience about human genetic modificationKeywords:GMO;Genetically Modified Organism;GMO Sapien;Cloning;Genomics;Designer Babies;Mitochondrial Transfer;Stem Cells;Infertility

"What I find troubling, exciting but scary, is that I find myself agreeing with an undertone, I do not support human germline genetic modification but with all the new information and perspectives available to me I have found myself questioning my own views and will be watching any developments with a fascinated interest I would rather not admit to."

The NODE
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A New York Times bestseller

“A smart and important book.”—Gretchen Reynolds, author of The First 20 Minutes
 
Publications as varied as Wired, Men’s Fitness, and The New Yorker are abuzz over the New York Times bestseller Faster, Higher, Stronger. In it, veteran journalist Mark McClusky explains how today’s top athletes are turning to advanced technology and savvy science to improve their performance. Sports buffs and readers of David Epstein and Gretchen Reynolds will want to join McClusky as he goes behind the scenes everywhere from the Olympics to the NBA Finals, from the World Series to the Tour de France, and from high-tech labs to neighborhood gyms to show how athletes at every level can incorporate cutting-edge science into their own workouts.


From the Trade Paperback edition.

The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

Here in a single source is an up-to-date description of the technology associated with the Li-Ion battery industry. It will be useful as a text for researchers interested in energy conversion for the direct conversion of chemical energy into electrical energy.

The new edition of Instant Notes in Molecular Biology has been revised and updated to include information on micro RNAs, RNA inhibition, functional genomics, proteomics, imaging, stem cells and bioinformatics. Written in an accessible style, the book will be a highly useful tool for studying molecular biology.

It was the most radical human-breeding experiment in American history, and no one knew how it turned out. The Repository for Germinal Choice–nicknamed the Nobel Prize sperm bank–opened to notorious fanfare in 1980, and for two decades, women flocked to it from all over the country to choose a sperm donor from its roster of Nobel-laureate scientists, mathematical prodigies, successful businessmen, and star athletes. But the bank quietly closed its doors in 1999–its founder dead, its confidential records sealed, and the fate of its children and donors unknown. In early 2001, award-winning columnist David Plotz set out to solve the mystery of the Nobel Prize sperm bank.

Plotz wrote an article for Slate inviting readers to contact him–confidentially–if they knew anything about the bank. The next morning, he received an email response, then another, and another–each person desperate to talk about something they had kept hidden for years. Now, in The Genius Factory, Plotz unfolds the full and astonishing story of the Nobel Prize sperm bank and its founder’s radical scheme to change our world.

Believing America was facing genetic catastrophe, Robert Graham, an eccentric millionaire, decided he could reverse the decline by artificially inseminating women with the sperm of geniuses. In February 1980, Graham opened the Repository for Germinal Choice and stocked it with the seed of gifted scientists, inventors, and thinkers. Over the next nineteen years, Graham’s “genius factory” produced more than two hundred children.


What happened to them? Were they the brilliant offspring that Graham expected? Did any of the “superman” fathers care about the unknown sons and daughters who bore their genes? What were the mothers like?

Crisscrossing the country and logging countless hours online, Plotz succeeded in tracking down previously unknown family members–teenage half-brothers who ended up following vastly different paths, mothers who had wondered for years about the identities of the donors they had selected on the basis of code names and brief character profiles, fathers who were proud or ashamed or simply curious about the children who had been created from their sperm samples.

The children of the “genius factory” are messengers from the future–a future that is bearing down on us fast. What will families be like when parents routinely “shop” for their kids’ genes? What will children be like when they’re programmed for greatness? In this stunning, eye-opening book, one of our finest young journalists previews America’s coming age of genetic expectations.


From the Hardcover edition.

Designed as a text for students and professionals pursuing careers in the fields of molecular biology, pharmacy and bioinformatics, the fourth edition continues to offer a fascinating and authoritative treatment of the entire spectrum of bioinformatics, covering a wide range of high-throughput technologies. In this edition, four new chapters are included and two chapters are updated. As a student-friendly text, it embodies several pedagogic features such as detailed examples, chapter-end problems, numerous tables, a large number of diagrams, flow charts, a comprehensive glossary and an up-to-date bibliography. This book should prove an invaluable asset to students and researchers in the fields of bioinformatics, biotechnology, computer-aided drug design, information technology, medical diagnostics, molecular biology and pharmaceutical industry. NEW TO THE FOURTH EDITION: • Includes four new chapters—Introduction to Biological Databases, Introduction to Phylogenetic, Methods of Phylogenic analysis and RNA Predict. • Updates chapters on Information Search and Data Retrieval and Alignment of Multiple Sequences. • Incorporates Problem Sets containing more than 250 problems and Multiple Choice Questions so that students can test their knowledge and understanding. Key Features • State-of-the-art technologies for gene identification, molecular modeling and monitoring of cellular processes • Data mining, analysis, classification, interpretation and efficient structure determination of genomes and proteomes • Importance of cell cycle for discovering new drug targets and their ligands • Computer-aided drug design and ADME-Tox property prediction Companion website www.phindia.com/rastogi provides useful resources for the teachers as well as for the students.

Published to mark the fiftieth anniversary of the Nobel Prize for Watson and Crick’s discovery of the structure of DNA, an annotated and illustrated edition of this classic book gives new insights into the personal relationships between James Watson, Frances Crick, Maurice Wilkins, and Rosalind Franklin, and the making of a scientific revolution.

The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism.  However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited.  This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention.  Support for this position is derived from critical assessment of current cancer theories.  Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.

"...you're talking about a yeti or bigfoot or sasquatch. Well now, you'll be amazed when I tell you that I'm sure they exist." —Jane Goodall on NPR

This is "The Big Book of Yetis." What the reader gets here is a world-class geneticist's search for evidence for the existence of Big Foot, yeti, or the abominable snowman.

Along the way, he visits sites of alleged sightings of these strange creatures, attends meetings of cryptozoologists, recounts the stories of famous monster-hunting expeditions, and runs possible yeti DNA through his highly regarded lab in Oxford. Sykes introduces us to the crackpots, visionaries, and adventurers who have been involved in research into this possible scientific dead-end over the past 100 years. Sykes is a serious scientist who knows how to tell a story, and this is a credible and engaging account.

Almost, but not quite human, the yeti and its counterparts from wild regions of the world, still exert a powerful atavistic influence on us. Is the yeti just a phantasm of our imagination or a survivor from our own savage ancestry? Or is it a real creature? This is the mystery that Bryan Sykes set out to unlock.

People have searched for the fountain of youth everywhere from Bimini to St. Augustine. But for a steadfast group of scientists, the secret to a long life lies elsewhere: in the lowly lab worm. By suppressing the function of just a few key genes, these scientists were able to lengthen worms’ lifespans up to tenfold, while also controlling the onset of many of the physical problems that beset old age. As the global population ages, the potential impact of this discovery on society is vast—as is the potential for profit.

With The Longevity Seekers, science writer Ted Anton takes readers inside this tale that began with worms and branched out to snare innovative minds from California to Crete, investments from big biotech, and endorsements from TV personalities like Oprah and Dr. Oz. Some of the research was remarkable, such as the discovery of an enzyme in humans that stops cells from aging. And some, like an oft-cited study touting the compound resveratrol, found in red wine—proved highly controversial, igniting a science war over truth, credit, and potential profit. As the pace of discovery accelerated, so too did powerful personal rivalries and public fascination, driven by the hope that a longer, healthier life was right around the corner. Anton has spent years interviewing and working with the scientists at the frontier of longevity science, and this book offers a behind-the-scenes look at the state-of-the-art research and the impact it might have on global public health, society, and even our friends and family.
With spectacular science and an unforgettable cast of characters, The Longevity Seekers has all the elements of a great story and sheds light on discoveriesthat could fundamentally reshape human life.