A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging.
Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach.
In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
The information you need to care for your athletes on and off the field. The Sports Medicine Field Manual is a downloadable resource, developed in partnership with the American Academy of Orthopaedic Surgeons (AAOS), the National Athletic Trainers’ Association (NATA), the American Medical Society for Sports Medicine (AMSSM), and the American Orthopaedic Society for Sports Medicine (AOSSM). Each section was written by a collaborative team of experts, including orthopaedic surgeons, athletic trainers and primary care physicians with experience in caring for athletes at all levels.
The Sports Medicine Field Manual is a reference for on-site evaluation and management of athletic injuries and conditions, as well as education beyond the point of care.
Based on current peer-reviewed evidence and standards of practice, it offers safe, accurate and proven information on more than 50 topics, including:
• Preparticipation evaluation
• On-site preparation, including staff and equipment needs
• Initial assessment and physical examination
• Evaluation and logistics
• Diagnostic testing and treatment
• Risk management and medical considerations
• Return to play
• Injuries by anatomical area or specific condition
Simple to search, plus bulleted text for quick reading, visuals to help promote understanding, and text and graphics which enlarge for easy reading.
Be ready for anything – with practical and reliable medical information to best manage the injuries and health issues of your athletes where and when you need it. Download the Sports Medicine Field Manual today.
Osteologists, archaeologists, anatomists, forensic scientists and paleontologists will all find practical information on accurately identifying, recovering, and analyzing and reporting on human skeletal remains and on making correct deductions from those remains.From the world renowned and bestselling team of osteologist Tim D. White, Michael T. Black and photographer Pieter A. FolkensIncludes hundreds of exceptional photographs in exquisite detail showing the maximum amount of anatomical informationFeatures updated and expanded coverage including forensic damage to bone and updated case study examplesPresents life sized images of skeletal parts for ease of study and reference
Effectively implement the newest techniques detailed in new and updated chapters on a variety of sports-specific and other acquired injuries, and chronic disorders.
Keep up with the latest advances in arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management
See conditions and treatments as they appear in practice thanks to detailed, full-color design, illustrations, and photographs.
Access the full contents online with streaming video of surgical and rehabilitation techniques, downloadable patient handouts, links to Pub Med, and regular updates at www.expertconsult.com.
Get a fresh perspective from seven new section editors, as well as an even more geographically diverse set of contributors.
Taking an application-oriented approach, the authors illustrate how material characteristics, tribological behavior, and loading impact the degradation of contacts, formation of intermetallics, and overall reliability and performance. Coverage is divided broadly into three sections, with the first focused on mechanics, tribology, materials, current and heat transfer, and basic reliability issues of electrical contacts. The next section explores applications, such as power connections, electronic connections, and sliding contacts, while the final section presents the diagnostic and monitoring techniques used to investigate and measure phenomena occurring at electrical contact interfaces. Numerous references to current literature reflect the fact that this book is the most comprehensive survey in the field.
Explore an impressive collection of data, theory, and practical applications in Electrical Contacts: Fundamentals, Applications, and Technology, a critical tool for anyone investigating or designing electrical equipment with improved performance and reliability in mind.
About the authors . . .
D. M. PIRRO is the Equipment Builder and OEM Manager, ExxonMobil Corporation, Fairfax, Virginia. The author or contributing editor of several scholarly articles on synthetic lubes, environmental awareness applications, grease technology, lubricant interchangeability, and oil analysis, Mr. Pirro is a Certified Lubrication Specialist and a member of the Society of Tribologists and Lubrication Engineers and the Association of Manufacturing Technology. He received the B.S. degree (1978) in mechanical engineering and the B.A. degree (1978) in business administration from Rutgers University, New Brunswick, New Jersey.
A. A. WESSOL is a part-time Lubrication Consultant for the ExxonMobil Corporation in Manassas, Virginia. Mr. Wessol retired from the Mobil Corporation after 24 years in various advanced technical positions. The author or coauthor of numerous professional papers on the environmental aspects of lubrication, plant engineering, hydraulics, and pneumatics, he received the B.S. degree (1972) in mathematics, physics, and chemistry from the University of Pittsburgh, Pennsylvania.
Eve Herold's Beyond Human examines the medical technologies taking shape at the nexus of computing, microelectronics, engineering, nanotechnology, cellular and gene therapies, and robotics. These technologies will dramatically transform our lives and allow us to live for hundreds of years. Yet, with these blessings come complicated practical and ethical issues, some of which we can predict, but many we cannot.
Beyond Human taps the minds of doctors, scientists, and engineers engaged in developing a host of new technologies while telling the stories of some of the patients courageously testing the radical new treatments about to come into the market.
Beyond Human asks the difficult questions of the scientists and bioethicists who seek to ensure that as our bodies and brains become ever more artificial, we hold onto our humanity. In this new world, will everyone have access to technological miracles, or will we end up living in a world of radical disparities? How will society accommodate life spans that extend into hundreds of years? Will we and our descendants be able to bring about the dream of a future liberated by technology, or will we end up merely serving the machines and devices that keep us healthy, smart, young, and alive?
Filling the void, Biotechnology Operations: Principles and Practices reflects this integrative philosophy, serving as a practical guide for students, professionals, or anyone else with interests in the biotech industry. Although many books emphasize specific technical aspects of biotech, this is perhaps the first to integrate essential concepts of product development and scientific and management skills with the seven functional areas of biotechnology:
Biomanufacturing Clinical trials Nonclinical studies Project management Quality assurance Quality control Regulatory affairs
A practical roadmap to optimizing biotechnology operations, this reference illustrates how to use specific product planning, design, and project management processes to seamlessly merge plans and efforts in the key functional areas. Applying lessons learned throughout the nascent history of biotech, author Michael Roy highlights developmental principles that could bring future products to market more safely and efficiently. Drawing from his experiences working in industry and teaching a graduate course at the University of Wisconsin, this hotly anticipated book clarifies basic methodologies and practices to help reduce risks and resolve problems as future technological discoveries are developed into tangible products.
This second book offers a unique quiz that will help you to classify your injury into one of four types. In this way, you will learn how to cure your pain, not someone else’s. Then the advice flows thick and fast. You will learn clever techniques that will help you to use your spine more efficiently, and discover how to think, eat, relax, and sleep away your pain. You’ll also find useful information on exercises, x-rays, medication and muscles, plus some tips on how to choose a spinal health practitioner. Of course, all of the advice will be tailored to your specific problem.
Because the cure uses well-proven techniques, your relief won’t just last a few days or weeks. You will feel better forever.
This atlas will serve as a valuable resource to orthopedic surgeons, neurosurgeons, and surgical trainees as well as physician assistants, surgical nurses, and all those involved in the operative care of patients undergoing spine surgery.
This book gives a comprehensive description of polymeric nanocomposites, both as bulk materials and as thin surface coatings, and their behavior and potential use in tribological applications. It provides the preparation techniques, friction and wear mechanisms, properties of polymeric nanocomposites, characterization, evaluation and selection methodology. It also provides various examples of application of polymeric nanocomposites.
* Provides a complete reference from the preparation to the selection of polymeric nanocomposites
* Explains the theory through examples of real-world applications
* More than 20 international tribology experts contribute to their area of expertise
Written by experts from around the world, the handbook covers all major classes of hydraulic fluids in detail, delving into chemistry, design, fluid maintenance and selection, and other key concepts. It also offers a rigorous overview of hydraulic fluid technology and evaluates the ecological benefits of water and its use as an important alternative technology. This complete overview discusses pumps and motors, valves, and reservoir design, as well as fluid properties and associated topics. These include air entrainment, modulus, lubrication and wear assessment by bench and pump testing, biodegradability, and fire resistance. Contributors also present particularly important material on biodegradable fluids and the use of water as a hydraulic fluid.
As the foremost resource on the design, selection, and testing of hydraulic systems and fluids used in engineering applications, this book contains new illustrations, data tables, and practical examples, all updated with essential information on the latest methods. To streamline presentation, relevant content from the first edition has been integrated into this new version, where appropriate. The result is a reference that helps readers develop an unparalleled understanding of the total hydraulic system, including essential hardware, fluid properties, and hydraulic lubricants.
The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression.
The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.
The Clinical Engineering Handbook meets a long felt need for a comprehensive book on all aspects of clinical engineering that is a suitable reference in hospitals, classrooms, workshops, and governmental and non-governmental organization. The Handbook’s thirteen sections address the following areas: Clinical Engineering; Models of Clinical Engineering Practice; Technology Management; Safety Education and Training; Design, Manufacture, and Evaluation and Control of Medical Devices; Utilization and Service of Medical Devices; Information Technology; and Professionalism and Ethics. The Clinical Engineering Handbook provides the reader with prospects for the future of clinical engineering as well as guidelines and standards for best practice around the world. From telemedicine and IT issues, to sanitation and disaster planning, it brings together all the important aspects of clinical engineering.Clinical Engineers are the safety and quality faciltators in all medical facilitiesThe most definitive, comprehensive, and up-to-date book available on the subject of clinical engineeringOver 170 contributions by leaders in the field of clinical engineering
The truth is that if you’ve never felt any kind of shoulder pain whatsoever, the chances are good that as you grow older, you will. Our bodies tend to lose muscle and bone mass as we age, and we become more susceptible to the aches and pains that may result.
But neither the weakness nor the pain is inevitable. The shoulder can be fixed, and the pain can go away. First, there’s a fix that cures the weakness and ends the pain. But there are also things you can do to prevent injury or strain in the first place, so that you never have to lose the strength, stability, and range of motion of the shoulder at all. Fix My Shoulder explores the anatomy and function of the shoulder, methods of preventing pain and injury, and treatments for healing that anyone can implement for better shoulder health and function.
Avoiding the hype of popular science and the pessimism of most social science, Nikolas Rose analyzes contemporary molecular biopolitics, examining developments in genomics, neuroscience, pharmacology, and psychopharmacology and the ways they have affected racial politics, crime control, and psychiatry. Rose analyzes the transformation of biomedicine from the practice of healing to the government of life; the new emphasis on treating disease susceptibilities rather than disease; the shift in our understanding of the patient; the emergence of new forms of medical activism; the rise of biocapital; and the mutations in biopower. He concludes that these developments have profound consequences for who we think we are, and who we want to be.
This edition includes new and updated information on aspiration of the joints, fracture reduction, traumatic lacerations, and multiple trauma.
Maintains the popular at-a-glance table format that makes finding essential information quick and convenient.
Contains useful clinical information on disorders, trauma, history, physical exam, radiology, surgical approaches, and minor procedures in every chapter.
Lists key information on bones, joints, muscles, and nerves in tables correlate to each Netter image.
Highlights key material in different colors—pearls in green and warnings in red—for easy reference. Features both plain film and advanced radiographic (CT and MRI) images, along with cross-sectional anatomic plates for an even more thorough visual representation of the material.
This "updated" second edition includes test-yourself images and notes. All other content is the same as the 2010 2nd edition.
This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention.
The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.
Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors.A comprehensive overview of switchable and responsive materials and surfacesIncludes in depth analysis of thermo-responsive polymers, photonic sensitive materials and peptide-based surfacesDetailed exploration of biological interactions of responsive and switchable surfaces, covering stimuli-sensitive polymers for drug delivery, surfaces with proteins/cells and application of polymers in medical devices
This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike.Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valvesOffers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systemsFull-color presentation throughout
Second Edition is Fully Revised and Updated
The second edition is revamped with the latest research and containing over 90 images of exercises demonstrated by professional trainers.
It provides the basis for Dr. Lau's program: Part 1 highlights current medical knowledge on Scoliosis, Part 2 outlines an in-depth nutritional program, and Part 3 teaches corrective exercises.In this book you will: - Uncover the most recent research on the true causes of scoliosis - Discover how bracing and surgery treat merely the symptom not the root cause of scoliosis - Find out what latest treatment work, what doesn't and why - The most common symptoms scoliosis sufferers have - How a quick scoliosis assessment of a teenager can help with their quality of life in later years - Discover how lack of proper nutrition creates illness in our bodies and affects the normal growth of the spine In-depth understanding of how muscles and ligaments work on the common types of scoliosis - Customize an exercise routine unique to your scoliosis to suit even the busiest schedule - What are the most effective exercises for scoliosis and what should be avoided at all cost - Tips and tricks to modify your posture and body mechanics to decrease scolisosis back pain - The best sitting, standing and sleeping postures for scoliosis - Learn from others with scoliosis in inspirational stories and case studies
With painstaking research and years of practice, Dr. Lau separates fact from fiction. In this book, he busts popular myths, one by one, and explores what approach works, what alternatives a scoliosis patient has and how it is possible to create a comprehensive plan to achieve peak physical and spinal health.
Inspired by the extraordinary resilience of the Aboriginal groups of Australia and native African tribes that rarely suffer from scoliosis, Dr. Lau prescribes an easy-to-follow, clinically proven program that harks back to what our bodies were originally designed for and need to survive on. This book will set you on the path to total recovery by simply following the three-step process.
“Modern medicine, alone, has failed to effectively manage the condition of Scoliosis,” said Dr. Lau. “The treatment program I designed combines ancient wisdom with modern research and technology, culminating in the best overall results. Today, as a practicing chiropractor and nutritionist, I am more certain than ever that scoliosis, and other disorders, can be prevented and treated effectively.”Who is the Health in Your Hands Program for?
The book is easy to read for anyone even without medical knowledge to understand but is in-depth enough and fully referenced for fitness & rehabilitation professionals. Medical professional that have purchased the book include Chiropractors, Personal Trainers, Yoga instructors, Osteopaths, Medical Doctors and Occupational Therapist.Testimonials
"I strongly recommend Dr. Lau's natural program as an effective and better alternative to conventional bracing and surgery. I am very impressed with the results! I think that every spinal specialist will find the information contained in this book useful." - Dr. Alan Kwan, D.O. Medical Director "The results were beyond my expectation with my scoliosis corrected. Even better, I avoided surgery! - Lucy Koh
The companion Scoliosis Exercises for Prevention and Treatment DVD is used to guide patients in properly performing the exercises detailed in the book. With ScolioTrack, patients use their iPhones as a tool to measure the curves in their spines and monitor their own progress.
For more information visit: www.hiyh.info
Key Features:An easy-to-read, bullet-style format that provides readable but not overwhelming content Surgical Pearls that tap into the experiences of surgeons who have mastered that procedure Common Clinical Questions (with answers) at the end of each chapter that highlight topics frequently encountered in the operating room and on board exams Superb visual examples that illuminate the procedures described Helpful appendices that cover positioning, spinal orthoses, and scales and outcome measures A first-of-its-kind, this handbook is designed to be the go-to guide for those conducting and involved in surgical spine treatment.
Allogeneic HSCT is a medical procedure in which a patient receives blood-forming stem cells from a genetically similar but not identical donor. This procedure is commonly performed for people with diseases of the blood, bone marrow, or certain cancers, but it remains risky with many possible complications. As such, experimental practice is reserved for preclinical animal models including the mouse and dog.
These animal models have been essential in developing transplant protocols, including preclinical testing of conditioning regimens, treatment of GVHD, and understanding the pathology of GVHD as well as the immunological mechanisms of GVHD and GVL effect. However, recent research has revealed significant species differences between humans and animal models that must be considered when relating animal model studies to clinical allogeneic HSCT scenarios.Brings together perspectives leading laboratories and clinical research groups to highlight advances from bench to the bedsideGuides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic HSCT scenariosCategorizes the published advances in various aspects of immune biology of allegeneic HSCT to illustrate opportunities for clinical applications
Christine Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast, is regarded as one of the most brilliant new minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metabolic pathway engineering. With a wealth of cutting edge research and analysis, this work also serves as an invaluable resource for those seeking to add their own contributions. Organized by topic, this 3000 page reference is available as two volumes that can be purchased individually or as a set.
This book is a practical guide and reference to the latest technology, operations and opportunities presented by clinical simulation. It shows how to develop and make efficient use of resources, and provides hands-on information to those tasked with setting up and delivering simulation facilities for medical, clinical and related purposes, and the development and delivery of simulation-based education programsA step-by-step manual to developing successful simulation programsShows how to design, construct, outfit and run simulation facilities for clinical education and research.The Residency Review Committee of the US Accreditation Council on Graduate Medical Education has begun requiring residency programs to have simulation as an integral part of their training programs.
Master the nuances of each new technique through step-by-step instructions and beautiful, detailed line drawings, intraoperative photographs, and surgical videos.
See exactly how it’s done. Watch master surgeons perform Partial and Primary TKR, Revision TKR, Tumor Replacement, Fracture Treatment, and over 160 videos on the expertconsult.com.
Find information quickly and easily thanks to a consistent, highly templated, and abundantly illustrated chapter format and streamlined text with many references and chapters appearing online only.Access the fully searchable contents of the book online at www.expertconsult.com, including 40 online-only chapters, a downloadable image library, expanded video collection, quarterly updates, and a glossary of TKR designs with images and text from various device manufacturers.
Grasp and apply the latest knowledge with expanded coverage of cartilage repair and regeneration techniques, expanded ligament techniques in allograft and autografts, computer robotics in surgical prognostics, fitting and techniques in partial and total knee arthroplasty, and more.
Consult with the best. Renowned knee surgeon and orthopaedic sports medicine authority Dr. W. Norman Scott leads an internationally diverse team of accomplished specialists—many new to this edition—who provide dependable guidance and share innovative approaches to reconstructive surgical techniques and complications management.
This monograph reviews the role played by TFS in masking, pitch perception, speech perception, and spatial hearing, and concludes that cues derived from TFS play an important role in all of these. Evidence is reviewed suggesting that cochlear hearing loss reduces the ability to use TFS cues. Also, the ability to use TFS declines with increasing age even when the audiogram remains normal. This provides a new dimension to the changes in hearing associated with aging, a topic that is currently of great interest in view of the increasing proportion of older people in the population.
The study of the role of TFS in auditory processing has been a hot topic in recent years. While there have been many research papers on this topic in specialized journals, there has been no overall review that pulls together the different research findings and presents and interprets them within a coherent framework. This monograph fills this gap.Contents:Processing of Sound in the Auditory System and Neural Representation of Temporal Fine StructureThe Role of TFS in MaskingThe Role of TFS in Pitch PerceptionThe Role of TFS in Speech PerceptionThe Influence of Hearing Loss and Age on the Binaural Processing of TFSOverview, Conclusions and Practical Implications
Readership: Medical professionals, academics and clinicians in hearing, life science students and biomedical researchers.
Key Features:Sensitivity to temporal fine structure (TFS) in sound is currently a hot topic, but no other book focuses on this topicThe book provides a critical review and interpretation of data on sensitivity to TFS and how sensitivity is affected by hearing loss and ageThe author has published extensively in this areaKeywords:Hearing;Hearing Loss;Age;Temporal Fine Structure;Envelope;Hearing Impairment
· cerebrovascular and transcranial
· lower and upper limb arterial
· deep vein thrombosis
· deep and superficial venous reflux
· renal, hepatoportal, mesenteric and penile.
Making Sense of Vascular Ultrasound is designed to give users a hands-on, practical approach to the diagnosis of vascular disease. This pocket-sized handbook provides easy to read, concise, point-form text and includes high-resolution ultrasound images and informative line diagrams.
Each regional chapter covers
· clinical presentations
· differential diagnosis
· what the doctor needs to know
· normal findings and criteria for disease as seen by ultrasound
· comprehensive protocols
· ultrasound images to collect for reports
The book also provides an overview of the physical principles of ultrasound, the physiology of blood flow, vascular pathology, setting up a vascular ultrasound diagnostic service, and interventional vascular ultrasound procedures.