A masterful synchronization of history and cutting-edge science shines new light on humanity's darkest diagnosis.
In the wake of the Cancer Genome Atlas project's failure to provide a legible roadmap to a cure for cancer, science writer Travis Christofferson illuminates a promising blend of old and new perspectives on the disease. Tripping over the Truth follows the story of cancer’s proposed metabolic origin from the vaunted halls of the German scientific golden age to modern laboratories around the world. The reader is taken on a journey through time and science that results in an unlikely connecting of the dots with profound therapeutic implications.
Transporting us on a rich narrative of humanity’s struggle to understand the cellular events that conspire to form malignancy, Tripping over the Truth reads like a detective novel, full of twists and cover-ups, blind-alleys and striking moments of discovery by men and women with uncommon vision, grit, and fortitude. Ultimately, Christofferson arrives at a conclusion that challenges everything we thought we knew about the disease, suggesting the reason for the failed war against cancer stems from a flawed paradigm that categorizes cancer as an exclusively genetic disease.
For anyone affected by this terrifying disease and the physicians who struggle to treat it, this book provides a fresh and hopeful perspective. It explores the new and exciting non-toxic therapies born from the emerging metabolic theory of cancer. These therapies may one day prove to be a turning point in the struggle against our ancient enemy. We are shown how the metabolic theory redraws the battle map, directing researchers to approach cancer treatment from a different angle, framing it more like a gentle rehabilitation rather than all-out combat. In a sharp departure from the current “targeted” revolution occurring in cancer pharmaceuticals, the metabolic therapies highlighted have one striking feature that sets them apart—the potential to treat all types of cancer because they exploit the one weakness that is common to every cancer cell: dysfunctional metabolism.
With contributions from Thomas Seyfried, PhD, author of Cancer as a Metabolic Disease; Miriam Kalamian, EdM, MS, CNS, author of Keto for Cancer; and Beth Zupec Kania, consultant nutritionist of The Charlie Foundation.
3rd edition changes:
The field of oncology massage is maturing into a discipline with a deeper and deeper body of knowledge. The 3rd edition of Medicine Hands reflects this maturation. Every chapter contains updated information and insights into massaging people affected by cancer. New chapters have been added to cover each stage of the cancer experience: treatment, recovery, survivorship, side effects from the disease, and end of life. These new chapters and organizational structure will make it easier for the reader to find the information needed to plan the massage session for a given client. As well, a new chapter has been added that focuses on the Pressure/Site/Positioning framework. This is the clinical framework around which the massage session is planned.
The scientific research on the effects of massage for people with cancer is updated to 2013. New in the 3rd edition is material devoted to massaging young adult survivors, the person with breast reconstruction, cording, and late effects as well as thoughts for therapists and clients who are considering the use of massage as part of a detoxification process.
All of the features most enjoyed by past readers have been retained—the inspirational sidebar quotes, client and therapist anecdotes, info boxes, and therapists questions and answers. To augment the learning process, written exercises have been added for student therapists and all of those who want to participate in their own learning. As well, sample session write-ups have been included to show the reader the variety of touch modalities that can be used to for people living with cancer.
Finally, the 3rd edition will be full color with new color photographs.
Cancer is not randomly distributed in the United States. Its incidence varies by race, ethnicity, socioeconomic status, and other geographic and demographic factors. This volume, co-published with the American Cancer Society, is the first to examine the biological, racial, and socioeconomic factors that influence cancer incidence and survival. In addition, it presents 15 previously unpublished, evidence-based interventions to reduce and eliminate cancer disparities.
The book explains the nature, scope, and causes of cancer disparities across different populations and then presents unique programs proven to reduce such inequalities in the areas of cancer prevention, screening and early detection, treatment, and survivorship. They represent a variety of cancers, populations, and communities across the U.S. Descriptions of each intervention include tests of effectiveness and are written in sufficient detail for readers to replicate them within their own communities.Key Features:
Offers an in-depth look at the latest research behind cancer disparitiesWritten by highly respected and published cancer researchersIncludes 15 never-before published, evidence-based interventions that readers can replicateDiscusses breast, colorectal, cervical, and other pernicious cancersIncludes interventions for African-American, Hispanic, Native American, and other populations
Rancour has an honest, humane, funny, and poetic style. She sweeps you along with her compassion, her wit, and her unerring ability to see into the truth of the matter. This book is for anyone who has an interest in what goes on in the patient rooms, hallways, stairwells, and elevators of a cancer hospital. You wont be able to put it down.
In this groundbreaking book, Gary Null debunks the commonly accepted belief that drugs and chemotherapy are the only cures for cancer and explores the alternative treatments that most mainstream doctors will never discuss with their patients. Dr. Null asserts that there are foods and supplements that boost the body’s immune system and can actually prevent and reverse cancer. Did you know that eating lemons and melons can help balance your body’s pH, which will help prevent and treat cancer? You knew that fiber is important for a healthy diet, but did you know that it lowers the risk of breast, colorectal, uterine, and prostate cancers? Have you heard of maitake mushrooms, which kill cancer cells by enhancing the activity of T-helper cells? In addition to diet, Dr. Null discusses important supplements and herbs and cutting-edge therapies you may never have heard of. With twenty-five cancer-fighting recipes and testimonials from individuals who have found health through Dr. Null’s methods, this book could save your life.
When you or a loved one is faced with a cancer diagnosis, the need for accurate and trusted medical information becomes urgent. Naturopathic physician Lise N. Alschuler and medical journalist Karolyn A. Gazella present an overview of what cancer is, its causes and preventative strategies, an in-depth approach to integrative treatment options, descriptions of key body functions, and discussions of more than twenty specific cancers. The Definitive Guide to Cancer, now in its third edition, encourages you to take an integrative approach that embraces both alternative and conventional therapies across the spectrum of cancer prevention, treatment, and healing.
From the Trade Paperback edition.
The AJCC Cancer Staging Atlas, 2nd Edition, is an official publication of the American Joint Committee on Cancer, the recognized international leader in state-of-the-art information on cancer staging. This Atlas has been created as a companion to the updated 7th Edition of the AJCC Cancer Staging Manual, which continues to disseminate the importance of anatomical and pathological staging in the management of cancer. This state-of-the-art, invaluable 2nd Edition includes a CD containing PowerPoint slides of all illustrations, additional color, and a user-friendly, easy-to-read layout. The AJCC Cancer Staging Atlas, 2nd Edition will serve as an indispensable reference for clinicians, registrars, students, trainees, and patients.
Since the third edition (2003), there have been significant changes in treatment and resources. Working with Dr. Judd Moul, the Chairman of Urology at Duke and one of the world's top experts on prostate cancer, Marks provides the most up-to- date information on diagnosis, treatment, and common questions.
Chapters are organized by site-specific disease. Each chapter presents the must-know key points, including treatment options by stage, relevant technical considerations, and important items for follow-ups. This crucial material makes the book an ideal companion for the practicing physician during rounds and other clinical settings. The book's organized format also lends itself to quick review for the board or MOC exams, and it can serve as a handy reference during a case review at a tumor board.
Key Features:The outline format and wealth of succinct tables make this a great quick reference Each chapter concludes with a list of selected, summarized studies relevant to the disease 51 disease-based chapters make it easy to find particular sites without having to sift through dense, broad text Supplemental sections at the end of the book provide quick access to normal tissue tolerance constraints as well as recommendations for managing symptoms after radiation therapy
In telling these stories, Lippe and Le alternate chapters. Lippe writes about the early signs that something was wrong; Le continues with a description of pancreatic cancer, its symptoms, and its treatments. Lippe talks about his prognosis, contemplates the prospect of death, and describes how he began to cope; Le explains the importance, for both doctor and patient, of balancing hope and truth. Lippe speaks frankly about the toll the disease takes on his marriage and family; Le offers a general picture of what most patients can expect with their illness. The book concludes with Lippe and Le’s reflections on their partnership in treating cancer, lessons they have learned, and their thoughts about the positive things that sometimes emerge from illness.
Pancreatic Cancer offers clear explanations of what the disease is, describes what people with the disease will feel physically and mentally, and discusses current treatments and future directions of research. The authors hope that their honest yet hopeful perspective will help all people with cancer and those who care about them.
Over the past half century, deaths from heart disease, stroke, and so many other killers have fallen dramatically. But cancer continues to kill with abandon. In 2013, despite a four-decade “war” against the disease that has cost hundreds of billions of dollars, more than 1.6 million Americans will be diagnosed with cancer and nearly six hundred thousand will die from it.
A decade ago, Clifton Leaf, a celebrated journalist and a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public’s immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress—brilliant young scientists—are now abandoning the search for a cure. “Through flowing prose Leaf delivers, alongside facts and data, stories on personalities involved in research, the fascinating process of solving an unusual and highly deadly cancer in Africa, and the heartbreaking realities of cancer treatment in children today. Leaf’s extensively investigated treatise will resonate with researchers and patients frustrated by the bureaucratic woes he delineates. Public policy makers, grant reviewers, and pharmaceutical researchers alike must consider Leaf’s indictment and proposed solutions” (Publishers Weekly). The Truth in Small Doses is that rare tale that will both outrage readers and inspire conversation and change.
An empathetic resource full of relatable patient stories, this book teaches patients and caregivers how to ask the right questions to get the best possible care--beginning at the moment of diagnosis. Drs. Jackson and Ryan explain how to work with a team of doctors and nurse practitioners to minimize symptoms and side effects while living as fully as possible in the face of cancer. They relay important information about understanding prognosis, and they translate what doctors mean when they describe tests, treatments, and medical procedures. Finally, they discuss hospice care and answer questions about continuing treatment and managing the final phase of life.
Based on new research and a groundbreaking program in which patients are treated with palliative care--along with the best cancer care--during the course of their illness, this honest and caring book provides the right advice to use at the right time throughout a journey with cancer. It allows a person with cancer to concentrate on living the best life possible, despite an uncertain future. Patients at every stage will find Living with Cancer a comprehensive, thoughtful, and accessible guide for navigating the illness and its treatment.
New information on developments in the molecular pathogenesis of this disease impacts how physicians approach and treat patients with CLL. The various predisposing factors for the disease are addressed along with current and future treatment modalities and recommended standards of care.
Key features include:introduction by Kanti Rai, MD who developed the Rai Classification and Staging system used in CLL diagnosis CLL in relationship to gene expression profiling and molecular abnormalities familial clustering and gene predisposition targeted therapy trials clinical patient management based upon stage and progression of disease
The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.
Since the first edition was published in 2006, Phillip M. Devlinís Brachytherapy has been acknowledged as the essential book on the practice. Inthis updated new edition, all chapters covering cancer sites have been significantly revised. Organized for specialists in several fields, Brachytherapy contains site-specific chapters that discuss how the evolving role of advanced image guidance has demonstrated greater efficacy and less toxicity. Clinical vignettes with images now accompany all site-specific chapters. The chapter on prostate brachytherapy has been expanded to include other indications in the genitourinary system, and there are two entirely new chaptersóone chronicling the history of brachytherapy and the other detailing the emergence of skin brachytherapy.
Dr. Devlin, a leading world authority on brachytherapy, has assembled other leaders in the field from world-renowned radiation oncology programs to enrichthis comprehensive text. From new data on medical outcomes to the costs and benefits of running a brachytherapy practice, Brachytherapy, Second Edition is the first and last word on what still is considered the most conformal radiotherapy technique in the field.
In the new edition:
Over 300 images accompany the chapter text and clinical vignettes
Essential tables and spreadsheets enhance the chapter on running a brachytherapy practice
Ten years of technological advancements are assimilated and reviewed in each site-specific chapter
Includes access to the fully-searchable downloadable ebook
From the Foreword:
ìAs education is essential to advance awareness of and proficiency in the full spectrum of brachytherapy applications, the appearance of the second edition of this highly regarded text is both a timely and most welcome event. The distinguished list of contributors to this work reads like a veritable ìWhoís Whoî of international brachytherapy expertise making this an indispensable resource for students and practitioners of this complex and challenging modality[Ö]A particularly welcome feature is the clinical vignettes at the close of every chapter that bring seemingly remote concepts to life in real world practical applications[Ö]With the second edition of Brachytherapy: Applications and Techniques, Dr. Devlin and colleagues give us a text that instills a profound appreciation for the critical value of this essential modality. This book makes it clear that brachytherapy not only works, it is an irreplaceable component of contemporary cancer care.î
--David Wazer, MD, FACRO, FACR, FASTRO, Professor and Chairman, Departments of Radiation Oncology, Alpert Medical School of Brown University, Providence, RI
Did you know ...Grapefruit can interact with over 100 drugs, but it may be useful for reducing blood pressure and for weight loss?ADHD over diagnosis is now recognized widely as a fact, and there are existing — and new ways — to avoid a misdiagnosis?Studies have been conducted demonstrating the utility of Omega 3 fatty acids, meditation, yoga, and melatonin for some important symptoms of ADHD, including executive functions?Vaccines have saved millions of lives in the last decade? But are they safe?Breast cancer rates are declining in the US, but have been steadily increasing in Japan?Doctors are getting better at predicting which chemotherapy will, and will not work, on certain cancers?There are vaccines against cancer?
This book reviews recent key, hard-won successes and findings from recent biomedical research. Written by one of the most ardent defenders of the public trust in science, it provides an accessible, detailed look at successes in translational biomedical and clinical research. The author provides an optimistic, forward-looking view for the possibility of change for the public good, cutting through the controversy and gets to very core of each topic. The public can be optimistic about the future of medicine, but only if they learn the facts of these advances, and learn what their doctors should be expected to know.
Highly referenced, and filled with interviews from experts and people directly involved in the research behind the new facts in each chapter, this book is a rich source of information on advances in biomedicine that you will want to share with your family & friends.Contents: PrefaceAbuses in MedicineOutrageous Acts of PseudoscienceWait ... Grapefruit is Bad for You?Hormone Receptor Status and Breast Cancer TreatmentFecal Microbiota TransplantationOverdiagnosis of ADHD: It's Their Mind, Not YoursVaccination Programs: Eradication of Infectious DiseasesChemosensitivity and Chemoresistance Assays in CancerA Very Special Kind of Brain Cancer SurgeryGenomics and Personalized MedicineRobot-Assisted SurgeryHallmarks and Principles of Translational Research SuccessFuture Medicine 1: Early Detection and Cures for Alzheimer's DiseaseFuture Medicine 2: Cancer VaccinesThe Future of Translational Research
Readership: Lay public, scientists, doctors, politicians, policy makers, public health workers, health care worker, investors.
Now she and her co-authors have brought together the answers to the questions that women face in chapters that cover everything from how to prepare for going to the hospital to when you come home Amy and her co-authors answer:
Why am I so tired all the time?
What about these drains?
Should I worry about Lymphedema?
Implants or flap procedure?
Although everyone's experience is slightly different depending upon one's individual choice: mastectomy alone or mastectomy with reconstruction; the majority of the information applies to all women who had a mastectomy.
Amy and her co-authors include chapters on key issues all women face including wound management, scar massage, dressing and bathing, emotional recovery, and more. And although mastectomy is frightening, the authors make clear that today's procedure is not what it used to be.
Now What'is the first resource to provide all the information that women need after mastectomy and breast reconstruction surgery so that they can focus on what matters most: healing and staying well.
The first main part of the book is subdivided into blood banking and transfusion medicine. Under blood banking, the chapters cover blood collection, donation process, component manufacturing, donor testing and storage; transfusion-medicine chapters examine the components for transfusion, pre-transfusion immunohematology testing, blood groups, blood products and their modifications, approaches to transfusion therapy in specific clinical settings, and transfusion reactions and complications. In addition, chapters that talk about apheresis, cellular therapy, and tissue banking in the hospital setting are included.
Hemostasis, the second main part of the book, is subdivided into three sections. The first section, clinical coagulation, includes chapters about neonatal thrombocytopenia, inherited platelet function disorders, immune thrombocytopenia, immune-mediated coagulopathies, congenital bleeding disorders, and acquired bleeding disorders. The second section relates to laboratory testing of coagulation, with chapters about laboratory assessments of platelet disorders, von Willebrand disease, coagulation factor disorders, fibrinogen and fibrinolysis, tests for hypercoagulable state and for activation of the coagulation system, and laboratory support for anticoagulation. The third section discusses coagulation factor products.
This book will be valuable for the education of trainees, practitioners, and future leaders in these fields.
A Doody's Core Title for 2017!
Featuring a superb compilation of chapters related to hematology and oncology derived from Harrison’s Principles of Internal Medicine, Nineteenth Edition (including content from the acclaimed Harrison’s DVD, now available here in print), this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find 57 chapters from more than 75 renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation.
• Each chapter contains relevant information on the genetics, cell biology, pathophysiology, and treatment of specific disease entities
• Chapters on hematopoiesis, cancer cell biology, and cancer prevention reflect the rapidly growing knowledge in these areas
• Integration of pathophysiology with clinical management
• High-yield board review questions make this text ideal for keeping current or preparing for the boards
• Valuable appendix of laboratory values of clinical importance
Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer.Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer.
Features a new full-color design throughout, as well as updated diagnostic algorithms.
Williams Manual of Hematology, Ninth Edition provides a quick-access summary of the epidemiology, etiology, pathogenesis, diagnostic criteria, differential diagnosis, and therapy of blood cell and coagulation protein disorders. The 93 chapters of the Manual are a distillation of the disease- and therapy-focused chapters from the Ninth Edition of Williams Hematology. The book has been carefully edited to deliver only the most clinical point-of-care facts, making differential diagnosis faster, easier, and more efficient.
Concise but comprehensive, this complete guide includes sections on:
• Initial Clinical Evaluation
• Disorders of Red Cells
• Disorders of Granulocytes
• Disorders of Monocytes and Macrophages
• Principles of Therapy for Neoplastic Hematological Disorders
• The Clonal Myeloid Disorders
• The Polyclonal Lymphoid Diseases
• The Clonal Lymphoid and Plasma Cell Diseases
• Disorders of Platelet and Hemostasis
• Disorders of Coagulation Proteins
• Thrombosis and Antithrombotic Therapy
• Transfusion and Hemapheresis
Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body.
Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.
The book includes all topics listed in the American Board of Internal Medicine (ABIM) blueprint as essential material for the Medical Oncology Certification Exam. The coverage spans all hematologic malignancies and solid tumors, beginning with the epidemiology, and followed by the etiology and risk factors of the disease, staging, signs and symptoms, diagnostic criteria, indications for treatment, prognostic factors, treatment recommendations, and special considerations. Later chapters review other major subspecialty areas found on the exam including cancer genetics and tumor biology, supportive and palliative care, bone marrow transplantation, and biostatistics. Each chapter includes key points summarized in digestible bullets for easy recall and self-assessment. And, now containing over 230 board style questions with answers and detailed rationales, Oncology Board Review, Second Edition is the go-to, quick review for any trainee preparing for initial certification and for oncologists preparing for recertification.New to this Edition:Includes over 230 board style questions and answers with rationalesNew chapter on Bone Marrow TransplantationThoroughly updated and revised chapters with all new treatment recommendations and FDA approvals for solid tumors and hematologic malignancies included.
The first edition described the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ß-subunit, 3 separate and independent molecules with totally sovereign physiological functions.
The second edition will include coverage of the many new discoveries that have been made in the last five years: hCG analogues may be the actual driving signal of all human cancers. The editor estimates that 40% of the out of date material will be excluded and replaced with 40% of the exciting new findings. The book will also have a much clearer pregnancy and cancer focus.It provides comprehensive information on hCG from basic science to clinical medicineThe second edition will include coverage of the many new discoveries that have been made in the last five yearsUpdated material with new findings in the field
Tomosynthesis produces quasi-three-dimensional images that can significantly enhance the visualization of important diagnostic features. This book highlights the flexibility of tomosynthesis systems for new clinical applications, and provides a detailed discussion of the tomosynthesis acquisition process and the impact of physical factors. It explores such topics as acquisition parameters, system components, modeling, image reconstruction algorithms, and system evaluation.Provides in-depth coverage of system design considerations, as well as image reconstruction strategies Describes the current state of clinical applications of tomosynthesis, including imaging of the breast and chest, as well as its use in radiotherapy Illustrates the merits of tomosynthesis imaging and its potential clinical applications in imaging of the breast and chest, as well as for radiation therapy
Divided into five sections, this text delves into the history and development of tomosynthesis. It introduces tomosynthesis imaging, discusses imaging system design considerations, and reviews image reconstruction algorithms that have been developed for tomosynthesis. It also describes system evaluation methodologies, emphasizes current clinical applications, and examines the future direction for tomosynthesis.
Over the course of the last decade, the treatment of breast cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of breast cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues, genetics, radiology, surgery, reconstruction, fertility radiation, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment. Breast Cancer: A Multidisciplinary Approach to Diagnosis and Management, written by a multidisciplinary team of authors representing a range of disciplines, is a valuable resource for physicians, fellows, nurses, physician assistants, physical therapists, and all health care providers involved in the treatment of breast cancer. Breast Cancer: A Multidisciplinary Approach to Diagnosis and Management summarizes the state-of-the-art issues related to the treatment of breast cancer and describes an approach for optimal multidisciplinary care for women who have been diagnosed with breast cancer or who are at higher risk to develop breast cancer.
About the Series
The Current Multidisciplinary Oncology series edited by Charles R. Thomas consolidates and integrates the varied aspects of multidisciplinary care for major topics in oncology, including breast, lung, prostrate, head and neck and more. The volumes in the Current Multidisciplinary Oncology series represent all related topic areas, including oncology, radiation oncology, pain, pathology, imaging, psychological support and the primary disease. In addition, each volume includes a chapter focusing on special populations and the disease's impact / difference on them, and discussion of future directions and quality of life issues. In addition each volume has a chapter written by a private practice oncologist
All Current Multidisciplinary Oncology title provide: Consolidation and integration of the varied aspects of multidisciplinary care for major topics in oncology Coverage of all related topic areas, including medical and surgical oncology, radiation oncology, pain, pathology, imaging, psychological support, and the primary disease A chapter focusing on special populations and the disease's impact / difference on them A chapter on community practice written by a private practice oncologist Discussion of quality-of-life issues