Emphasizing state-of-the-art pharmacological and therapeutic approaches in controlling pathophysiological processes in the airways, Pharmacology and Therapeutics of Airway Disease reviews normal and abnormal physiological, biochemical and molecular aspects of the respiratory tract.
Covering the basic mechanisms of inflammatory cell activation and pathophysiology in disease, therapeutic ways of controlling inflammation, reversing or preventing airflow obstruction, and symptomatic treatments of advanced disease.
With several important large scaled trials becoming available and our knowledge of COPD's determinants rapidly growing, it was essential to update Clinical Management of Chronic Obstructive Pulmonary Disease with a second edition that will enable physicians to stay informed, aid in the clinical diagnosis, and the proper treatment of COPD
Within this text expert analysis will examine:
What is neuroplasticity? Is it possible to change your brain? Norman Doidge’s inspiring guide to the new brain science explains all of this and more
An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable, and proving that it is, in fact, possible to change your brain. Psychoanalyst, Norman Doidge, M.D., traveled the country to meet both the brilliant scientists championing neuroplasticity, its healing powers, and the people whose lives they’ve transformed—people whose mental limitations, brain damage or brain trauma were seen as unalterable. We see a woman born with half a brain that rewired itself to work as a whole, blind people who learn to see, learning disorders cured, IQs raised, aging brains rejuvenated, stroke patients learning to speak, children with cerebral palsy learning to move with more grace, depression and anxiety disorders successfully treated, and lifelong character traits changed. Using these marvelous stories to probe mysteries of the body, emotion, love, sex, culture, and education, Dr. Doidge has written an immensely moving, inspiring book that will permanently alter the way we look at our brains, human nature, and human potential.
From the Trade Paperback edition.
By examining fossils and DNA, he shows us that our hands actually resemble fish fins, our heads are organized like long-extinct jawless fish, and major parts of our genomes look and function like those of worms and bacteria. Your Inner Fish makes us look at ourselves and our world in an illuminating new light. This is science writing at its finest—enlightening, accessible and told with irresistible enthusiasm.
"America's funniest science writer" (Washington Post) Mary Roach explores the science of keeping human beings intact, awake, sane, uninfected, and uninfested in the bizarre and extreme circumstances of war.
Grunt tackles the science behind some of a soldier's most challenging adversaries—panic, exhaustion, heat, noise—and introduces us to the scientists who seek to conquer them. Mary Roach dodges hostile fire with the U.S. Marine Corps Paintball Team as part of a study on hearing loss and survivability in combat. She visits the fashion design studio of U.S. Army Natick Labs and learns why a zipper is a problem for a sniper. She visits a repurposed movie studio where amputee actors help prepare Marine Corps medics for the shock and gore of combat wounds. At Camp Lemmonier, Djibouti, in east Africa, we learn how diarrhea can be a threat to national security. Roach samples caffeinated meat, sniffs an archival sample of a World War II stink bomb, and stays up all night with the crew tending the missiles on the nuclear submarine USS Tennessee. She answers questions not found in any other book on the military: Why is DARPA interested in ducks? How is a wedding gown like a bomb suit? Why are shrimp more dangerous to sailors than sharks? Take a tour of duty with Roach, and you’ll never see our nation’s defenders in the same way again.
Horowitz introduces the reader to dogs’ perceptual and cognitive abilities and then draws a picture of what it might be like to be a dog. What’s it like to be able to smell not just every bit of open food in the house but also to smell sadness in humans, or even the passage of time? How does a tiny dog manage to play successfully with a Great Dane? What is it like to hear the bodily vibrations of insects or the hum of a fluorescent light? Why must a person on a bicycle be chased? What’s it like to use your mouth as a hand? In short, what is it like for a dog to experience life from two feet off the ground, amidst the smells of the sidewalk, gazing at our ankles or knees?
Inside of a Dog explains these things and much more. The answers can be surprising—once we set aside our natural inclination to anthropomorphize dogs. Inside of a Dog also contains up-to-the-minute research—on dogs’ detection of disease, the secrets of their tails, and their skill at reading our attention—that Horowitz puts into useful context. Although not a formal training guide, Inside of a Dog has practical application for dog lovers interested in understanding why their dogs do what they do. With a light touch and the weight of science behind her, Alexandra Horowitz examines the animal we think we know best but may actually understand the least. This book is as close as you can get to knowing about dogs without being a dog yourself.
In his last book, Neil Shubin delved into the amazing connections between human anatomy—our hands, our jaws—and the structures in the fish that first took over land 375 million years ago. Now, with his trademark clarity and exuberance, he takes an even more expansive approach to the question of why we are the way we are. Starting once again with fossils, Shubin turns his gaze skyward. He shows how the entirety of the universe's 14-billion-year history can be seen in our bodies. From our very molecular composition (a result of stellar events at the origin of our solar system), he makes clear, through the working of our eyes, how the evolution of the cosmos has had profound effects on the development of human life on earth.
From the Hardcover edition.
Stay Young Forever (or Die Trying)
SPRING CHICKEN is a full-throttle, high-energy ride through the latest research, popular mythology, and ancient wisdom on mankind's oldest obsession: How can we live longer? And better? In his funny, self-deprecating voice, veteran reporter Bill Gifford takes readers on a fascinating journey through the science of aging, from the obvious signs like wrinkles and baldness right down into the innermost workings of cells. We visit cutting-edge labs where scientists are working to "hack" the aging process, like purging "senescent" cells from mice to reverse the effects of aging. He'll reveal why some people live past 100 without even trying, what has happened with resveratrol, the "red wine pill" that made headlines a few years ago, how your fat tissue is trying to kill you, and how it's possible to unlock longevity-promoting pathways that are programmed into our very genes. Gifford separates the wheat from the chaff as he exposes hoaxes and scams foisted upon an aging society, and arms readers with the best possible advice on what to do, what not to do, and what life-changing treatments may be right around the corner.
An intoxicating mixture of deep reporting, fascinating science, and prescriptive takeaway, SPRING CHICKEN will reveal the extraordinary breakthroughs that may yet bring us eternal youth, while exposing dangerous deceptions that prey on the innocent and ignorant.
The first section of the Atlas contains photographs of all views of the skull; the second is made up of photos of the disarticulated bones. The next section pictures muscle attachments, and the final two show radiological and anthropological landmarks. Bones, sutures, landmarks, and foramina are identified in the sharp and detailed photographs, and legends on the facing pages group terms by category for easy and rapid identification. The radiology and anthropology sections focus on the requirements of the practitioner.
Two criteria guided the compilation of this atlas: ease of use and convenience as a study tool. The text--presented as legends keyed to the photographs--groups terms according to entries, such as bone, foramen, or landmark. Each foramen is supplied with a description of structures that it transmits. The keying of the features to legends on a facing page makes the book particularly easy to use as a study guide and avoids clutter or obscuring of detail on the pictures themselves. The size and clarity of the pictures allow easy viewing of each labeled structure. Small regions with many landmarks are enlarged to show detail. Multiple pictures are provided of any single complex view to prevent clutter and confusion. Such attention to detail and user needs makes this atlas is an excellent study and reference tool.
This remarkable medical parallel launched Natterson-Horowitz on a journey of discovery that reshaped her entire approach to medicine. She began to search for other connections between the human and animal worlds: Do animals get breast cancer, anxiety-induced fainting spells, sexually transmitted diseases? Do they suffer from obsessive-compulsive disorder, bulimia, addiction?
The answers were astonishing. Dinosaurs suffered from brain cancer. Koalas catch chlamydia. Reindeer seek narcotic escape in hallucinogenic mushrooms. Stallions self-mutilate. Gorillas experience clinical depression.
Joining forces with science journalist Kathryn Bowers, Natterson-Horowitz employs fascinating case studies and meticulous scholarship to present a revelatory understanding of what animals can teach us about the human body and mind. “Zoobiquity” is the term the authors have coined to refer to a new, species-spanning approach to health. Delving into evolution, anthropology, sociology, biology, veterinary science, and zoology, they break down the walls between disciplines, redefining the boundaries of medicine.
Zoobiquity explores how animal and human commonality can be used to diagnose, treat, and heal patients of all species. Both authoritative and accessible, offering cutting-edge research through captivating narratives, this provocative book encourages us to see our essential connection to all living beings.
What separates your mind from an animal’s? Maybe you think it’s your ability to design tools, your sense of self, or your grasp of past and future—all traits that have helped us define ourselves as the planet’s preeminent species. But in recent decades, these claims have eroded, or even been disproven outright, by a revolution in the study of animal cognition. Take the way octopuses use coconut shells as tools; elephants that classify humans by age, gender, and language; or Ayumu, the young male chimpanzee at Kyoto University whose flash memory puts that of humans to shame. Based on research involving crows, dolphins, parrots, sheep, wasps, bats, whales, and of course chimpanzees and bonobos, Frans de Waal explores both the scope and the depth of animal intelligence. He offers a firsthand account of how science has stood traditional behaviorism on its head by revealing how smart animals really are, and how we’ve underestimated their abilities for too long.
People often assume a cognitive ladder, from lower to higher forms, with our own intelligence at the top. But what if it is more like a bush, with cognition taking different forms that are often incomparable to ours? Would you presume yourself dumber than a squirrel because you’re less adept at recalling the locations of hundreds of buried acorns? Or would you judge your perception of your surroundings as more sophisticated than that of a echolocating bat? De Waal reviews the rise and fall of the mechanistic view of animals and opens our minds to the idea that animal minds are far more intricate and complex than we have assumed. De Waal’s landmark work will convince you to rethink everything you thought you knew about animal—and human—intelligence.
BALANCE is the first book written for a general audience that examines the mysteries of the human balance system--the astonishingly complicated mechanisms that allow our bodies to counteract the force of gravity as we move through space. A scientific, historical, and practical exploration of how balance works, BALANCE also provides the keys to remaining upright for as long as humanly possible. From simple motion sickness to astronauts' "space stupids," and from fetal somersaults to the Flying Wallendas, McCredie guides readers on a delightful quest to elevate balance to its rightful place in the pantheon of the senses.
An important resource for all those involved in rabbit production, this book is also vital reading for students and researchers of animal science and meat production, as well as the keen amateur rabbit enthusiast.
This book can be used as a text for a year long graduate course in statistics, computer science, or mathematics, for self-study, and as an invaluable research reference on probabiliity and its applications. Particularly worth mentioning are the treatments of distribution theory, asymptotics, simulation and Markov Chain Monte Carlo, Markov chains and martingales, Gaussian processes, VC theory, probability metrics, large deviations, bootstrap, the EM algorithm, confidence intervals, maximum likelihood and Bayes estimates, exponential families, kernels, and Hilbert spaces, and a self contained complete review of univariate probability.
"The most scientifically important dog in over a century." —Brian Hare
Chaser has fascinated dog lovers and scientists alike. Her story reveals the potential for taking out dialogue with dogs well beyond "fetch." When retired psychology professor John Pilley first got his new Border collie puppy, Chaser, he wanted to explore the boundaries of language learning and communication between humans and man's best friend. Exhibiting intelligence previously thought impossible in dogs, Chaser soon learned the names of more than a thousand toys and sentences with multiple elements of grammar. Chaser's accomplishments are revolutionizing the way we think about the intelligence of animals. John and Chaser's inspiring journey demonstrates the power of learning through play and opens our eyes to the boundless potential in the animals we love.
From the coasts of Indonesia to the rainforests of Peru, venomous animals are everywhere—and often lurking out of sight. Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world.
Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out.
Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated.
Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.
This book received the Award of Excellence in an Illustrated Medical Book from the Association of Medical Illustrators. It is organized by individual organism to facilitate classroom presentation.
This illustrated, full-color primary dissection manual is ideal for use by students or practitioners working with vertebrate anatomy. This book is also recommended for researchers in vertebrate and functional morphology and comparative anatomy. The result of this exceptional work offers the most comprehensive treatment than has ever before been available.* Received the Award of Excellence in an Illustrated Medical Book from the Association of Medical Illustrators
* Expertly rendered award-winning illustrations accompany the detailed, clear dissection direction
* Organized by individual organism to facilitate classroom presentation
* Offers coverage of a wide range of vertebrates
* Full-color, strong pedagogical aids in a convenient lay-flat presentation
Jonathan Balcombe, animal behaviorist and author of the critically acclaimed Pleasurable Kingdom, draws on the latest research, observational studies and personal anecdotes to reveal the full gamut of animal experience—from emotions, to problem solving, to moral judgment. Balcombe challenges the widely held idea that nature is red in tooth and claw, highlighting animal traits we have disregarded until now: their nuanced understanding of social dynamics, their consideration for others, and their strong tendency to avoid violent conflict. Did you know that dogs recognize unfairness and that rats practice random acts of kindness? Did you know that chimpanzees can trounce humans in short-term memory games? Or that fishes distinguish good guys from cheaters, and that birds are susceptible to mood swings such as depression and optimism?
With vivid stories and entertaining anecdotes, Balcombe gives the human pedestal a strong shake while opening the door into the inner lives of the animals themselves.
Published by Teton New Media in the USA and distributed by Manson Publishing outside of North America.
The Fifth Edition, like the earlier editions, is a must for anyone interested in comparative physiology, poultry science, veterinary medicine, and related fields. This volume establishes the standard for those who need the latest and best information on the physiology of birds.Thoroughly updated and revisedCoverage of both domestic and wild birdsNew larger formatOnly comprehensive, single volume devoted to birds
Whole Heart, Whole Horse focuses on this idea, covering such subjects as gathering information from the horse, turning rider/trainer mistakes into positive experiences, developing realistic boundaries between you and your horse, understanding how and why horses release energy from real or perceived traumas, and reaching a comfortable balance point between horse and rider. Rashid analyzes developing softness, consistency, dependability, trust, and peace of mind in both horses and humans, as well as how to become a leader whom your horse will willingly want to follow and work with.
Full of examples that extend beyond the training pen, Whole Heart, Whole Horse offers good sense and information that will make you a more astute, capable, and sensitive horseman and person.
Primitive Fishes includes ground-breaking information in the field, including highlighs of the most unusual characteristics amongst the various species, which might have allowed these fishes to persist virtually unchanged through evolutionary time. This volume is essential for all comparative physiologists, fish biologists, and paleontologists.Provides an analysis of the evolutionary significance of physiological adaptations in "ancient fishes"Offers insights on the evolution of higher vertebratesThe only single source that presents an in-depth discussion of topics related to the physiology of ancient fishes
Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it—a French convent girl who found herself changing sex at puberty; children who, echoing Homer’s Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity. This elegant, humane, and engaging book “captures what we know of the development of what makes us human” (Nature).
Animals Make Us Human is the culmination of almost thirty years of research, experimentation, and experience. This is essential reading for anyone who’s ever owned, cared for, or simply cared about an animal.
Penguin Biology is an invaluable reference for ornithologists, animal behaviorists, animal physiologists, marine zoologists, marine ecologists, evolutionary biologists, and Antarctic researchers.Major topics covered include Breeding, feeding, and foragingBehavior and evolutionEnergetics and physiologyNew fossil material
This text was written for graduate and advanced undergraduate students in the life sciences, including those taking courses in cell physiology, cell biophysics, and cell biology. Selected parts of this book can be used for courses in neurobiology, electrobiology, electrophysiology, secretory biology, biological transport, and muscle contraction. Students majoring in engineering, biomedical engineering, physics, and chemistry may use the book to understand the living state of matter. The text can serve as a reference tool for s postdoctoral scholars and faculty engaged in biological research. Medical, dental, and allied health students can also use this book to complement other textbooks in medical/mammalian physiology.
The Man Who Touched His Own Heart tells the raucous, gory, mesmerizing story of the heart, from the first "explorers" who dug up cadavers and plumbed their hearts' chambers, through the first heart surgeries-which had to be completed in three minutes before death arrived-to heart transplants and the latest medical efforts to prolong our hearts' lives, almost defying nature in the process.
Thought of as the seat of our soul, then as a mysteriously animated object, the heart is still more a mystery than it is understood. Why do most animals only get one billion beats? (And how did modern humans get to over two billion-effectively letting us live out two lives?) Why are sufferers of gingivitis more likely to have heart attacks? Why do we often undergo expensive procedures when cheaper ones are just as effective? What do Da Vinci, Mary Shelley, and contemporary Egyptian archaeologists have in common? And what does it really feel like to touch your own heart, or to have someone else's beating inside your chest?
Rob Dunn's fascinating history of our hearts brings us deep inside the science, history, and stories of the four chambers we depend on most.
Now in its third edition, Primate Anatomy discusses species that are new to science since the last edition with details concerning anatomical features among primates that were re-discovered. New research in molecular primatology is also included due to recent relevant findings in molecular biology in accordance with new technology. The basics of biological taxonomy are introduced, along with photographs of all major groups. Important new and controversal issues make this edition key for every primatologists, anthropologist, and anatomist.Offers up-to-date reviews of molecular primatology and primate genomicsConcentrates on living primates and their overall biologyDiscusses the genetic connection of function where knownIntroduces primate genomics for the first time in a textbookProvides instructive and comprehensive review tablesIncludes many unique, novel and easily understandable illustrations
In the late spring and early summer, as a bee colony becomes overcrowded, a third of the hive stays behind and rears a new queen, while a swarm of thousands departs with the old queen to produce a daughter colony. Seeley describes how these bees evaluate potential nest sites, advertise their discoveries to one another, engage in open deliberation, choose a final site, and navigate together--as a swirling cloud of bees--to their new home. Seeley investigates how evolution has honed the decision-making methods of honeybees over millions of years, and he considers similarities between the ways that bee swarms and primate brains process information. He concludes that what works well for bees can also work well for people: any decision-making group should consist of individuals with shared interests and mutual respect, a leader's influence should be minimized, debate should be relied upon, diverse solutions should be sought, and the majority should be counted on for a dependable resolution.
An impressive exploration of animal behavior, Honeybee Democracy shows that decision-making groups, whether honeybee or human, can be smarter than even the smartest individuals in them.
The volume is intended for graduate-level biology students as well as researchers who wish to gain a better understanding of applied bioinformatics and who wish to use bioinformatics technologies to assist in their research. The volume would also be of value to bioinformatics developers, particularly those from a computing background, who would like to understand the application of computational tools for biological research. Each chapter would include a comprehensive introduction giving an overview of the fundamentals, aimed at introducing graduate students and researchers from diverse backgrounds to the field and bring them up-to-date on the current state of knowledge. To accommodate the broad range of topics in applied bioinformatics, chapters have been grouped into themes: gene and genome analysis, molecular genetic analysis, gene expression analysis, protein and proteome analysis, metabolome analysis, phenome data analysis, literature mining and bioinformatics tool development. Each chapter and theme provides an introduction to the biology behind the data describes the requirements for data processing and details some of the methods applied to the data to enhance biological understanding.