This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike.
New to this edition:
*Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves
*Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems
Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation?
Using first-hand experience at the cutting edge of science, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge illustrates one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe.
Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden describe the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.
– Winner, Stephen Hawking Medal for Science Communication
This inspiring guide shows you how to use Arduino to create gadgets for measuring noise, weather, electromagnetic interference (EMI), water purity, and more. You’ll also learn how to collect and share your own data, and you can experiment by creating your own variations of the gadgets covered in the book. If you’re new to DIY electronics, the first chapter offers a primer on electronic circuits and Arduino programming.Use a special microphone and amplifier to build a reliable noise monitor Create a gadget to detect energy vampires: devices that use electricity when they’re “off” Examine water purity with a water conductivity device Measure weather basics such as temperature, humidity, and dew point Build your own Geiger counter to gauge background radiation Extend Arduino with an Ethernet shield—and put your data on the Internet Share your weather and radiation data online through Pachube
This new edition discusses biological systems that can be analyzed quantitatively, and how advances in the life sciences have been aided by the knowledge of physical or engineering analysis techniques. The volume is organized into 18 chapters encompassing thermodynamics, electricity, optics, sound, solid mechanics, fluid mechanics, and atomic and nuclear physics. Each chapter provides a brief review of the background physics before focusing on the applications of physics to biology and medicine. Topics range from the role of diffusion in the functioning of cells to the effect of surface tension on the growth of plants in soil and the conduction of impulses along the nervous system. Each section contains problems that explore and expand some of the concepts. The text includes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics in the body.
Physics in Biology and Medicine will be a valuable resource for students and professors of physics, biology, and medicine, as well as for applied health workers.Provides practical techniques for applying knowledge of physics to the study of living systemsPresents material in a straight forward manner requiring very little background in physics or biologyIncludes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics in the body
Easily review and visualize important facts with more than 1,000 high-quality pictures, charts, lists, boxes, tables, differential diagnoses and suggested readings.
Get all you need for daily reference with a concise, yet comprehensive format.Interpret the findings generated from each high-tech imaging modality used to study the brain, spine, head, and neck, including diffusion weighted imaging, perfusion weighted imaging, CT angiography, MR angiography, and MR spectroscopy.
Carry and consult this resource easily with its new, more compact book size.
Detect harmful gases, dust particles such as smoke and smog, and upper atmospheric haze—substances and conditions that are often invisible to your senses. You’ll also discover how to use the scientific method to help you learn even more from your atmospheric tests.Get up to speed on Arduino with a quick electronics primer Build a tropospheric gas sensor to detect carbon monoxide, LPG, butane, methane, benzene, and many other gases Create an LED Photometer to measure how much of the sun’s blue, green, and red light waves are penetrating the atmosphere Build an LED sensitivity detector—and discover which light wavelengths each LED in your Photometer is receptive to Learn how measuring light wavelengths lets you determine the amount of water vapor, ozone, and other substances in the atmosphere Upload your data to Cosm and share it with others via the Internet
"The future will rely on citizen scientists collecting and analyzing their own data. The easy and fun gadgets in this book show everyone from Arduino beginners to experienced Makers how best to do that."
--Chris Anderson, Editor in Chief of Wired magazine, author of Makers: The New Industrial Revolution (Crown Business)
Interested in unraveling the physics of living things? Here's your starting point. Biophysics Demystified is the fast and easy way to understand this fascinating topic.
Written in a step-by-step format, this practical guide begins with an introduction to the science of biophysics, covering biophysical techniques and applications. Next, you'll learn the principles of physics, biology, and chemistry required to understand biophysics, including free energy, entropy, and statistical mechanics. Biomolecules and the forces that influence their structure and conformation are also covered, as are protein, nucleic acid, and membrane biophysics. Detailed examples and concise explanations make it easy to understand the material, and end-of-chapter quizzes and a final exam help reinforce key concepts.
It's a no-brainer! You'll get:Molecular, subcellular, physiological, anatomical, and environmental biophysics The laws of thermodynamics as they apply to biophysical systems Forces affecting conformation in biological molecules The composition and structure of carbohydrates, lipids, proteins, and nucleic acids The fluid mosaic model
Simple enough for a beginner, but challenging enough for an advanced student, Biophysics Demystified makes this interdisciplinary subject easy to master.
One of the most diverse of modern scientific disciplines, biophysics applies methods and technologies from physics to the study of biological systems and phenomena, from the human nervous system to soil erosion to global warming. What are the best options for satisfying the world's growing energy demands? How can we feed the world's growing population? How can we contain, or reverse, global warming? How can we vouchsafe a plentiful supply of potable water for future generations? These are among the critical questions to which biophysicists work to provide answers.Biophysics courses are increasingly taken by students of biology, physics, chemistry, biochemistry, physiology, statistics, bioengineering, neuroscience, computer science, pharmacology, agriculture,and many more Provides a friendly, unintimidating overview of the material covered in a typical college-level biophysics course A one-stop reference, course supplement and exam preparation tool for university students currently enrolled in an introductory biophysics courses An indispensable resource for those studying the natural sciences, biological sciences, and physics, as well as math, statistics,computer science, pharmacology and many other disciplines The current job market for people well versed in biophysics is very strong, and biophysics is currently listed as one of the fast-growing occupations in the North America
The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression.
The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.
This concise introductory paperback surveys and relates basic physics to living systems. It discusses biological systems that can be analyzed quantitatively, and how advances in the life sciences have been aided by the knowledge of physical or engineering analysis techniques.
This text is designed for premed students, doctors, nurses, physiologists, or other applied health workers, and other individuals who wish to understand the nature of the mechanics of our bodies.- Provides practical techniques for applying knowledge of physics to the study of living systems
- Presents material in a straight forward manner requiring very little background in physics or biology
- Includes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics
The second edition of the classic text has been revised and extended to meet the needs of today’s practising and training MRI technologists who intend to sit for the American Registry of Magnetic Resonance Imaging Technologists (ARMRIT) examination. It provides Q&As on topics listed in the content specifications offered by the American Registry for Radiologic Technologists (AART) and offers the user with a comprehensive review of the principles and applications of MRI to prepare them for the examination.
Image-Guided Interventions, a title in the Expert Radiology Series, brings you in-depth and advanced guidance on all of today’s imaging and procedural techniques. Whether you are a seasoned interventionalist or trainee, this single-volume medical reference book offers the up-to-the-minute therapeutic methods necessary to help you formulate the best treatment strategies for your patients. The combined knowledge of radiology experts from around the globe provides a broad range of treatment options and perspectives, equipping you to avoid complications and put today's best approaches to work in your practice.
"... the authors and editors have succeeded in providing a book that is both useful, instructive and practical" Reviewed by RAD Magazine, March 2015Formulate the best treatment plans for your patients with step-by-step instructions on important therapeutic radiology techniques, as well as discussions on equipment, contrast agents, pharmacologic agents, antiplatelet agents, and protocols.Make effective clinical decisions with the help of detailed protocols, classic signs, algorithms, and SIR guidelines.Make optimal use of the latest interventional radiology techniques with new chapters covering ablation involving microwave and irreversible electroporation; aortic endografts with fenestrated grafts and branch fenestrations; thoracic endografting (TEVAR); catheter-based cancer therapies involving drug-eluting beads; sacroiliac joint injections; bipedal lymphangiography; pediatric gastrostomy and gastrojejunostomy; and peripartum hemorrhage. Know what to look for and how to proceed with the aid of over 2,650 state-of-the-art images demonstrating interventional procedures, in addition to full-color illustrations emphasizing key anatomical structures and landmarks. Quickly reference the information you need through a functional organization highlighting indications and contraindications for interventional procedures, as well as tables listing the materials and instruments required for each. Access the fully searchable contents, online-only material, and all of the images online at Expert Consult.
As advances in algorithms and computer technology have bolstered the digital signal processing capabilities of real-time sonar, radar, and non-invasive medical diagnostics systems, cutting-edge military and defense research has established conceptual similarities in these areas. Now civilian enterprises can use government innovations to facilitate optimal functionality of complex real-time systems. Advanced Signal Processing details a cost-efficient generic processing structure that exploits these commonalities to benefit commercial applications.
Learn from a Renowned Defense Scientist, Researcher, and Innovator
The author preserves the mathematical focus and key information from the first edition that provided invaluable coverage of topics including adaptive systems, advanced beamformers, and volume visualization methods in medicine. Integrating the best features of non-linear and conventional algorithms and explaining their application in PC-based architectures, this text contains new data on:
Advances in biometrics, image segmentation, registration, and fusion techniques for 3D/4D ultrasound, CT, and MRI
Fully digital 3D/ (4D: 3D+time) ultrasound system technology, computing architecture requirements, and relevant implementation issues
State-of-the-art non-invasive medical procedures, non-destructive 3D tomography imaging and biometrics, and monitoring of vital signs
Cardiac motion correction in multi-slice X-ray CT imaging
Space-time adaptive processing and detection of targets interference-intense backgrounds comprised of clutter and jamming
With its detailed explanation of adaptive, synthetic-aperture, and fusion-processing schemes with near-instantaneous convergence in 2-D and 3-D sensors (including planar, circular, cylindrical, and spherical arrays), the quality and illustration of this text’s concepts and techniques will make it a favored reference.
Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges.Learn the fundamentals of biodesign and DNA engineeringExplore important ethical issues raised by examples of synthetic biologyInvestigate the BioBuilder labs that probe the design-build-test cycleTest synthetic living systems designed and built by engineersMeasure several variants of an enzyme-generating genetic circuitModel "bacterial photography" that changes a strain’s light sensitivityBuild living systems to produce purple or green pigmentOptimize baker’s yeast to produce ?-carotene
Each chapter of the book investigates a facet of the physical world, including the drag on small projectiles; the importance of diffusion and convection; the size-dependence of acceleration; the storage, conduction, and dissipation of heat; the relationship among pressure, flow, and choice in biological pumps; and how elongate structures tune their relative twistiness and bendiness. Vogel considers design-determining factors all too commonly ignored, and builds a bridge between the world described by physics books and the reality experienced by all creatures. Glimpses of Creatures in Their Physical Worlds contains a wealth of accessible information related to functional biology, and requires little more than a basic background in secondary-school science and mathematics.
Drawing examples from creatures of land, air, and water, the book demonstrates the many uses of biological diversity and how physical forces impact biological organisms.
Quickly grasp the radiology fundamentals you need to know—including basic science, image interpretation, and terminology—with the popular "programmed learning" approach, which promotes fast learning and reference.
Discern the nuances between modalitiesby comparing CT and MR images as well as traditional radiographs. View detailed clinical images covering all the image types you'll see on the boards including digital quality radiographs and an introduction of PET imaging, plus more advanced imaging such as CT and MRI than ever before.
Test your skills and simulate the exam experiencewith updated content aligned with the new MCQ-format Board exam for easy preparation and review.
Benefit the from more robust interactive offeringsin an e-book format.
Reference key information quickly and easily thanks to a consistent, user-friendly format and a unique two-part organization (radiologic approaches to specific joints and full description of the individual common arthritides) that facilitates finding the exact information you need for any joint in the body.Improve the accuracy of your diagnoses by interpreting radiographs and comparing them with correlating MRI images.
Benefit from the latest advancements and techniques found in completely revised and rewritten chapters.
Understand the nuances and subtleties of how arthritides present through over 350 high-quality digital images.
This book provides a roadmap to the broad and varied career development opportunities in bioengineering, biotechnology, and related fields. Eminent practitioners lay out career paths related to academia, industry, government and regulatory affairs, healthcare, law, marketing, entrepreneurship, and more.
Lifetimes of experience and wisdom are shared, including "war stories," strategies for success, avoidance of common pitfalls, and discussions of the authors’ personal views and motivations. Career Development in Bioengineering and Biotechnology is an indispensable guide to some of the most exciting career and professional growth opportunities in science, engineering, and beyond, and a "must read" for anyone interested in a career related to this burgeoning field.
From the Foreword by U.S. National Medal of Science Laureate and Institute Professor Robert Langer, Massachusetts Institute of Technology: "This book provides a wealth of information and should serve as an excellent resource...The editors have gone to great effort to discuss a variety of critical topics in the burgeoning areas of bioengineering and biotechnology."
From the Introduction by Dr. Bruce Alberts, President Emeritus of the U.S. National Academy of Sciences and Co-chair of the InterAcademy Council: "I am very impressed with the enormous dedication and skill that created this major, highly-original contribution – I know of nothing like it."
From the Editorial by Dr. Joachim Nagel, President, International Union for Physical and Engineering Sciences in Medicine, and past president of the International Federation for Medical and Biological Engineering: "This book provides all the answers and can be highly recommended as the ultimate guide to anyone interested in bioengineering and biotechnology. The book arrives at a crucial time, and catapults bioengineering and biotechnology to the forefront of disciplines and to a rightly held pinnacle of inspiration for engineers, scientists, and technologists."
From the Afterword by Dr. Shu Chien, President, Biomedical Engineering Society and past president of the American Physiological Society and of the American Institute of Medical and Biological Engineering: "...this is truly an outstanding book that is the first of its kind...certainly a pioneering contribution."
Praise for the Book
"Bioengineering and Biotechnology are emerging as distinct disciplines amid the biological revolution and during a period of rapid globalization. These interesting times offer us unprecedented opportunities for professional and personal growth. This book covers many important areas of opportunity, including entrepreneurship, finance, law, and education, with a global perspective. The legacy of our times will include how well we used our rapidly advancing technologies to improve the world around us. This book provides a roadmap for the contributions of Bioengineering and Biotechnology in this quest."
-James E. Moore, PhD, Texas A&M University
"This book will be essential reading for all those seeking career guidance in bioengineering and biotechnology."
-Tony Bradshaw, PhD, Director bioProcessUK - BioIndustry Association (BIA), Chairman, The Royal Academy of Engineering/BIA Life Scientists' Career Seminars
"...the topics [are] quite extensive covering definitions, core curriculum, career opportunities, including a wide range of alternative career pathways as well as social and ethical issues. The material covered is unlike any of the standard publications related to these fields of activity... [the book] can be read at different stages of one's career."
-Joseph D. Bronzino, PhD, Trinity College
"...once I started reading it, [I] could not put it down. In less than three days, I read it all, absorbing the stories and details as if I was consummed by watching a high action movie... The breath and depth of the wisdom is phenomenal, and the stories shared by the writers are moving, inspiring, and shine of intelligence in seizing one's own passion and talents and turning them into stellar professional careers."
-Nathalie Gosset, MS, MBA, Head of Marketing, Alfred Mann Institute for Biomedical Engineering, University of Southern California
"This is a functional book with immediate impact, and is very helpful to those who need and desperately want help in making a career choice."
- Jonathan Newman, Graduate Student in Biomedical Engineering, Georgia Institute of Technology, USA
"This is an exciting undertaking and very well thought through and balanced. I enjoyed very much reading the chapters I have reviewed. Congratulations to all contributors and the editors of this book."
- Gudrun Zahlmann, PhD, Director of Business Development, Siemens Medical Systems, Germany
"I am very excited about this book. As a bioengineering educator, I am always looking for information that can provide guidance for students as they prepare for their careers. The contributors in this book are so enthusiastic about their careers that many of the chapters made me want to switch careers on the spot! I believe that engineering students do not receive enough guidance on alternative career paths. This book will very much help fill the void."
- Judy Cezeaux, PhD, Professor of Biomedical Engineering, Western New England College, Massachusetts, USA
The volume is intended for graduate-level biology students as well as researchers who wish to gain a better understanding of applied bioinformatics and who wish to use bioinformatics technologies to assist in their research. The volume would also be of value to bioinformatics developers, particularly those from a computing background, who would like to understand the application of computational tools for biological research. Each chapter would include a comprehensive introduction giving an overview of the fundamentals, aimed at introducing graduate students and researchers from diverse backgrounds to the field and bring them up-to-date on the current state of knowledge. To accommodate the broad range of topics in applied bioinformatics, chapters have been grouped into themes: gene and genome analysis, molecular genetic analysis, gene expression analysis, protein and proteome analysis, metabolome analysis, phenome data analysis, literature mining and bioinformatics tool development. Each chapter and theme provides an introduction to the biology behind the data describes the requirements for data processing and details some of the methods applied to the data to enhance biological understanding.
The Handbook of MRI Technique has proved highly successful in guiding the uninitiated through scanning techniques and helping more experienced technologists to improve image quality. The third edition of this highly successful book has been fully revised and updated to consider new technologies and developments essential to good practice.
The book is split into two parts. Part 1 considers the main aspects of theory that relate to scanning and also includes practical tips on gating, equipment use, patient care and safety, and information on contrast media. Part 2 provides step by step instruction for examining each anatomical area, beginning with a basic anatomy section, followed by sections on indications, patient positioning, equipment, artefacts and tips on optimizing image quality. A section of problem-solving exercises completes the book.
Now in full color throughout with over 200 illustrations this book will continue to appeal to radiographers new to MRI and regular users who are looking for information on alternative techniques and suggestions on protocol modifications.
Completely revised and updated
Over 100 brand new photographs and line drawings
Written by technologists for technologists
With contributions from MRI technologists in the USA and Australia
Suitable for users of all types of MRI systems
Erik Seedhouse is eminently qualified to describe the effects of large accelerations on the body. In addition to being the author of several previously published Springer Praxis books, he has developed astronaut-training protocols and is the training director for Astronauts for Hire (A4H). He is also the Canadian Forces’ High Risk Acceleration Training Officer.
For more than two decades, readers faced with a diagnosis of breast cancer have relied on Dr. Susan Love's Breast Book to guide them through the frightening thicket of research and opinion to find the best options for their particular situations. This sixth edition explains advances in targeted treatments, hormonal therapies, safer chemotherapy, and immunologic approaches as well as new forms of surgery and radiation. There is extensive guidance for the many women now living for years with metastatic breast cancer. With Dr. Love's warm support, readers can sort the facts from the fads, ask the right questions, and recognize when a second opinion might be wise.
"This is a thoroughly up-to-date text, divided into manageable topics, at a very reasonable price and I thoroughly recommend it to anyone who needs updating in the field of paediatrics or paediatric imaging." RAD, February 2014Determine the best modality for each patient with state-of-the art discussions of the latest pediatric imaging techniques. Quickly grasp the fundamentals you need to know through a more precise, streamlined format, reorganized by systems and disease processes, as well as "Teaching Boxes" that highlight key points in each chapter.Apply all the latest pediatric advances in clinical fetal neonatology techniques, technology, and pharmacology.Achieve accurate diagnoses as safely as possible. Increased coverage of MRI findings and newer imaging techniques for all organ systems emphasizes imaging examination appropriateness and safety.Reap the fullest benefit from the latest neuroimaging techniques including diffusion tensor imaging, fMRI, and susceptibility weighted imaging. Keep current with the latest pediatric radiological knowledge and evidence-based practices. Comprehensive updates throughout include new and revised chapters on prenatal imaging; newer anatomic and functional imaging techniques (including advances in cardiac imaging); disease classifications and insights into imaging disease processes; and advanced imaging topics in neurological, thoracoabdominal, and musculoskeletal imaging.Compare your findings to more than 10,000 high-quality radiology images.Access the full text online at Expert Consult including illustrations, videos, and bonus online-only pediatric imaging content.
Special features:More than 60 new ultrasound images in the second edition that were obtained with state-of-the-art equipment for the highest quality resolutionA helpful foundation on standard sectional planes for abdominal scanning, with full-color photographs demonstrating probe placement on the body and diagrams of organs shown Front and back cover flaps displaying normal sonographic dimensions of organs for easy reference
Covering all relevant anatomic markers, measurable parameters, and normal values, and including both transverse and longitudinal scans, this pocket-sized reference is an essential learning tool for medical students, radiology residents, ultrasound technicians, and medical sonographers.
Glean all essential, up-to-date, need-to-know informationto effectively interpret CTs and the salient points needed to make accurate diagnoses.
Review how the anatomyof each body area appears on a CT scan.
Grasp each procedure and review key steps quicklywith a comprehensive yet concise format.
Achieve optimal results with step-by-step instructionson how to perform all current CT techniques.
Compare diagnoses with a survey of major CT findingsfor a variety of common diseases—with an emphasis on those findings that help to differentiate one condition from another.
Make effective use of 64-slice MDCT and dual source CT scannerswith coverage of the most current indications. Stay current extensive updates of clinical guidelines that reflect recent changes in the practice of CT imaging, including (ACCP) Diagnosis and Management of Lung Cancer guidelines, paraneoplastic and superior vena cava syndrome, reactions to contrast solution and CT-guided needle biopsy.
Get a clear view of the current state of imagingfrom extensively updated, high-quality images throughout.
Access the complete contents online at ExpertConsult.