From the conquest of the Mediterranean beginning in the third century BC to the destruction of the Roman Empire at the hands of barbarian invaders some seven centuries later, we discover the most critical episodes in Roman history: the spectacular collapse of the 'free' republic, the birth of the age of the 'Caesars', the violent suppression of the strongest rebellion against Roman power, and the bloody civil war that launched Christianity as a world religion.
At the heart of this account are the dynamic, complex but flawed characters of some of the most powerful rulers in history: men such as Pompey the Great, Julius Caesar, Augustus, Nero and Constantine. Putting flesh on the bones of these distant, legendary figures, Simon Baker looks beyond the dusty, toga-clad caricatures and explores their real motivations and ambitions, intrigues and rivalries.
The superb narrative, full of energy and imagination, is a brilliant distillation of the latest scholarship and a wonderfully evocative account of Ancient Rome.
BIOS Instant Notes in Microbiology, Fourth Edition, is fully up-to-date and covers:
The next big human pandemic—the next disease cataclysm, perhaps on the scale of AIDS or the 1918 influenza—is likely to be caused by a new virus coming to humans from wildlife. Experts call such an event “spillover” and they warn us to brace ourselves. David Quammen has tracked this subject from the jungles of Central Africa, the rooftops of Bangladesh, and the caves of southern China to the laboratories where researchers work in space suits to study lethal viruses. He illuminates the dynamics of Ebola, SARS, bird flu, Lyme disease, and other emerging threats and tells the story of AIDS and its origins as it has never before been told. Spillover reads like a mystery tale, full of mayhem and clues and questions. When the Next Big One arrives, what will it look like? From which innocent host animal will it emerge? Will we be ready?
Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are.
The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people.
Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. It will change both our view of nature and our sense of where we belong in it.
Microbiology is a fascinating field that explores life down tothe tiniest level. Did you know that your body contains morebacteria cells than human cells? It's true. Microbes are essentialto our everyday lives, from the food we eat to the very internalsystems that keep us alive. These microbes include bacteria, algae,fungi, viruses, and nematodes. Without microbes, life on Earthwould not survive. It's amazing to think that all life is sodependent on these microscopic creatures, but their impact on ourfuture is even more astonishing. Microbes are the tools that allowus to engineer hardier crops, create better medicines, and fuel ourtechnology in sustainable ways. Microbes may just help us save theworld.
Microbiology For Dummies is your guide to understandingthe fundamentals of this enormously-encompassing field. Whetheryour career plans include microbiology or another science or healthspecialty, you need to understand life at the cellular level beforeyou can understand anything on the macro scale.Explore the difference between prokaryotic and eukaryoticcellsUnderstand the basics of cell function and metabolismDiscover the differences between pathogenic and symbioticrelationshipsStudy the mechanisms that keep different organisms active andalive
You need to know how cells work, how they get nutrients, and howthey die. You need to know the effects different microbes have ondifferent systems, and how certain microbes are integral toecosystem health. Microbes are literally the foundation of alllife, and they are everywhere. Microbiology For Dummies willhelp you understand them, appreciate them, and use them.
After four decades of assuming that the conquest of all infectous diseases was imminent, people on all continents now find themselves besieged by AIDS, drug-resistant tuberculosis, cholera that defies chlorine water treatment, and exotic viruses that can kill in a matter of hours.
Based on extensive interviews with leading experts in virology, molecular biology, disease ecology and medicine, as well as field research in sub-Saharan Africa, Western Europe, Central America and the United States, The Coming Plague takes readers from the savannas of eastern Bolivia to the rain forests of northern Zaire on a harrowing, fifty year journey through our battles with the microbes, and tells us what must be done to prevent the coming plague.
Whether it is asthma, food or pollen allergies, type-1 diabetes, lupus, multiple sclerosis, or Crohn’s disease, everyone knows someone who suffers from an allergic or autoimmune disorder. And if it appears that the prevalence of these maladies has increased recently, that’s because it has—to levels never before seen in human history. These days no fewer than one in five—and likely more—Americans suffers from one of these ailments. We seem newly, and bafflingly, vulnerable to immune system malfunction. Why? Science writer Moises Velasquez-Manoff explains the latest thinking about this problem and explores the remarkable new treatments in the works.
In the past 150 years, improved sanitation, water treatment, and the advent of vaccines and antibiotics have saved countless lives, nearly eradicating diseases that had plagued humanity for millennia. But now, a growing body of evidence suggests that the very steps we took to combat infections also eliminated organisms that kept our bodies in balance. The idea that we have systematically cleaned ourselves to illness challenges deeply entrenched notions about the value of societal hygiene and the harmful nature of microbes. Yet scientists investigating the rampant immune dysfunction in the developed world have inevitably arrived at this conclusion. To address this global “epidemic of absence,” they must restore the human ecosystem.
This groundbreaking book explores the promising but controversial “worm therapy”—deliberate infection with parasitic worms—in development to treat autoimmune disease. It explains why farmers’ children so rarely get hay fever, why allergy is less prevalent in former Eastern Bloc countries, and how one cancer-causing bacterium may be good for us. It probes the link between autism and a dysfunctional immune system. It investigates the newly apparent fetal origins of allergic disease—that a mother’s inflammatory response imprints on her unborn child, tipping the scales toward allergy. In the future, preventive treatment—something as simple as a probiotic—will necessarily begin before birth.
An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
An Epidemic of Absence considers the critical immune stimuli we inadvertently lost as we modernized, and the modern ills we may be able to correct by restoring them. At stake is nothing less than our health, and that of our loved ones. Researchers, meanwhile, have the good fortune of living through a paradigm shift, one of those occasional moments in the progress of science when a radically new way of thinking emerges, shakes things up, and suggests new avenues of treatment. You’ll discover that you’re not you at all, but a bustling collection of organisms, an ecosystem whose preservation and integrity require the utmost attention and care.
Public sanitation and antibiotic drugs have brought about historic increases in the human life span; they have also unintentionally produced new health crises by disrupting the intimate, age-old balance between humans and the microorganisms that inhabit our bodies and our environment. As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"— an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes—which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones—each custom-designed for maximum health benefits.
Fortunately for you, there's Schaum's Outlines. More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test your skills.
This Schaum's Outline gives you:Practice problems with full explanations that reinforce knowledge Coverage of the most up-to-date developments in your course field In-depth review of practices and applications
Fully compatible with your classroom text, Schaum's highlights all the important facts you need to know. Use Schaum's to shorten your study time-and get your best test scores!
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In The Fever, the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we've invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria's jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.
From the Trade Paperback edition.
Includes New and Updated Material
Now in its second edition, this work is the culmination of research and discussions with technical experts, as well as USP and FDA representatives on various topics of interest to the pharmaceutical microbiologist and those responsible for the microbial quality of products, materials, equipment, and manufacturing facilities. New in this edition is an entire chapter dedicated to the topic of biofilms and their impact on pharmaceutical and biopharmaceutical operations. The subject of rapid methods in microbiology has been expanded and includes a discussion on the validation of alternative microbiological methods and a case study on microbial identification in support of a product contamination investigation.
Substantially updated and revised, this book assists readers in understanding the fundamental issues associated with pharmaceutical microbiology and provides them with tools to create effective microbial contamination control and microbial testing programs for the areas under their responsibility.
* Only available work to cover the entire whisky process from raw material to delivery to the market in such a comprehensive manner
* Includes a chapter on marketing and selling whisky
* Foreword written by Alan Rutherford, former Chairman and Managing Director of United Malt and Grain Distillers Ltd.
The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.Contains the applications of pharmaceutical microbiology in sterile and non-sterile productsPresents the practical aspects of pharmaceutical microbiology testingProvides contamination control risks and remediation strategies, along with rapid microbiological methodsIncludes bioburden, endotoxin, and specific microbial risksHighlights relevant case studies and risk assessment scenarios
This book provides an understanding of the microbial challenges to the safety of low aw foods, and a historic backdrop to the paradigm shift now highlighting low aw foods as vehicles for foodborne pathogens. Up-to-date facts and figures of foodborne illness outbreaks and product recalls are included. Special attention is given to the uncanny ability of Salmonella to persist under dry conditions in food processing plants and foods. A section is dedicated specifically to processing plant investigations, providing practical approaches to determining sources of persistent bacterial strains in the industrial food processing environment. Readers are guided through dry cleaning, wet cleaning and alternatives to processing plant hygiene and sanitation. Separate chapters are devoted to low aw food commodities of interest including spices, dried dairy-based products, low aw meat products, dried ready-to-eat cereal products, powdered infant formula, nuts and nut pastes, flours and meals, chocolate and confectionary, dried teas and herbs, and pet foods. The book provides regulatory testing guidelines and recommendations as well as guidance through methodological and sampling challenges to testing spices and low aw foods for the presence of foodborne pathogens. Chapters also address decontamination processes for low aw foods, including heat, steam, irradiation, microwave, and alternative energy-based treatments.
The core information is presented in a clear and concise way,with extensive use of diagrams, algorithms, tables and boxes. Allchapters have been updated to reflect current best practice and theannotated bibliographies and lists of web-based resources have beenextended. The chapters on HIV, tuberculosis and malaria haveundergone particularly extensive revision, reflecting rapid changesin these areas since the last edition.
Lecture Notes: Tropical Medicine is particularlyaimed at postgraduate doctors attending tropical medicine courses,as well as medical students taking a tropical medicine electiveperiod. It will also be useful to a wide range of other healthprofessionals involved with medicine in the tropics, or importedtropical disease.
Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others.Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.
Vaccinated is not a biography; Hilleman's experience forms the basis for a rich and lively narrative of two hundred years of medical history, ranging across the globe and throughout time to take in a cast of hundreds, all caught up, intentionally or otherwise, in the story of vaccines. It is an inspiring and triumphant tale, but one with a cautionary aspect, as vaccines come under assault from people blaming vaccines for autism and worse. Paul Offit clearly and compellingly rebuts those arguments, and, by demonstrating how much the work of Hilleman and others has gained for humanity, shows us how much we have to lose.
The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces this book presents a fresh, new approach to the teaching of immunology.
After an introduction to the basic structure of the immune system, the book looks at two important families of signalling molecules: cytokines and chemokines, before covering the workings of the mucosal immune system. It continues by examining immunity against the four major groups of pathogens - viruses, bacteria, fungi and parasites, and concludes by looking at disorders of the immune system, mucosal tumour immunology and the process of vaccination.A fresh, new approach to the subject focusing on mucosal and body surfaces.Describes the mucosal immune systems of the gastrointestinal, respiratory and urogenital tracts, as well as the skin.Details the important roles of cytokines and chemokines in an immune response.Separate chapters devoted to immunity against viruses, bacteria, fungi and parasites.Includes chapter summaries, boxes with topics of special interest and an extensive glossary.Clearly written and well- illustrated in full colour throughout.
Students across a range of disciplines, including biology, biochemistry, biomedicine, medicine and veterinary sciences, will find this book invaluable, both as an introduction to basic immunology and as a guide to mucosal immune defence mechanisms.
Stem Cell Research For Dummies offers a balanced,plain-English look at this politically charged topic, cutting awaythe hype and presenting the facts clearly for you, free fromdebate. It explains what stem cells are and what they do, thelegalities of harvesting them and using them in research, thelatest research findings from the U.S. and abroad, and theprospects for medical stem cell therapies in the short and longterm.Explains the differences between adult stem cells andembryonic/umbilical cord stem cellsProvides both sides of the political debate and the pros andcons of each side's opinionsIncludes medical success stories using stem cell therapy andits promise for the future
Comprehensive and unbiased, Stem Cell Research ForDummies is the only guide you need to understand this volatileissue.
Paul Falkowski looks "under the hood" of microbes to find the engines of life, the actual working parts that do the biochemical heavy lifting for every living organism on Earth. With insight and humor, he explains how these miniature engines are built—and how they have been appropriated by and assembled like Lego sets within every creature that walks, swims, or flies. Falkowski shows how evolution works to maintain this core machinery of life, and how we and other animals are veritable conglomerations of microbes.
A vibrantly entertaining book about the microbes that support our very existence, Life's Engines will inspire wonder about these elegantly complex nanomachines that have driven life since its origin. It also issues a timely warning about the dangers of tinkering with that machinery to make it more "efficient" at meeting the ever-growing demands of humans in the coming century.
This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating “Immunomovie" that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles.Over 200 elegant 2-4 color illustrations36 full-color plates of basic and clinical items of interestTake-home message and “Did You Get It? self-test quiz at the end of each chapter6 Appendices that provide topic enrichment60-minute "Immunomovie" illustrating the immune response to bacterial, viral and parasitic infections
A Planet of Viruses is Carl Zimmer’s eye-opening look at the hidden world of viruses. Zimmer, the popular science writer and author of National Geographic’s award-winning blog The Loom, has updated this edition to include the stories of new outbreaks, such as Ebola, MERS, and chikungunya virus; new scientific discoveries, such as a hundred-million-year-old virus that infected the common ancestor of armadillos, elephants, and humans; and new findings that show why climate change may lead to even deadlier outbreaks. Zimmer’s lucid explanations and fascinating stories demonstrate how deeply humans and viruses are intertwined. Viruses helped give rise to the first life-forms, are responsible for many of our most devastating diseases, and will continue to control our fate for centuries. Thoroughly readable, and as reassuring as it is frightening, A Planet of Viruses is a fascinating tour of a formidable hidden world.
In addition to a number of informative changes to the textthroughout the book, the final four chapters have beensignificantly updated and extended to reflect the striking advancesmade in recent years in the applications of gene cloning and DNAanalysis in biotechnology.
Gene Cloning and DNA Analysis remains an essentialintroductory text to a wide range of biological sciences students;including genetics and genomics, molecular biology, biochemistry,immunology and applied biology. It is also a perfect introductorytext for any professional needing to learn the basics of thesubject. All libraries in universities where medical, life andbiological sciences are studied and taught should have copiesavailable on their shelves.
"… the book content is elegantly illustrated and wellorganized in clear-cut chapters and subsections… there is aFurther Reading section after each chapter that contains severalkey references… What is extremely useful, almost everyreference is furnished with the short but distinct author'sremark."
–Journal of Heredity, 2007 (on the previousedition)
Microorganisms in Foods 5, 7, and the second edition of Microorganisms in Foods 6 are for anyone using microbiological testing and/or engaged in setting Microbiological Criteria, whether for the purpose of Governmental Food Inspection and Control or in Industry, and for those identifying the most effective use of microbiological testing in the food chain. The contents are essential reading for food processors, food microbiologists, food technologists, veterinarians, public health workers and regulatory officials. For students in Food Science and Technology they offer a wealth of information on Food Microbiology and Food Safety Management, with many references for further study.
The information has been prepared by the International Commission on Microbiological Specifications for Foods (ICMSF). The ICMSF was formed in response to the need for internationally acceptable and authoritative decisions on microbiological limits for foods moving in international commerce. Currently the membership consists of eighteen food microbiologists from eleven countries, drawn from governmental laboratories in public health, agriculture, and food technology, from universities and from the food industry.
"A very well-written book suitable for use as a reference ortextbook for an undergraduate subject in cell signalling. Forresearchers interested in the molecular basis of cell signallingand how aberrant regulation of cell signalling proteins causesdiseases, this is an excellent resource of biochemical andstructural information." –Australian Biochemist, August2009
"From basics to details, this is an elegantly written andcarefully edited book. The chapters on cell cycle control andoncogenesis are particularly fascinating and valuable to biomedicalresearch. This is the book to have if you are interested inmolecular mechanisms of signal transduction. It is a greatintroduction to the literature that will be welcomed by studentsand experts alike." –Doody's, January 2009
This text is a concise and accessible introduction to thedynamic but complex field of signal transduction. Rather thansimply cataloguing all signalling molecules and delineating everyknown pathway, this book aims to break signalling down into commonelements and activities – the ‘nuts and bolts’ ofcellular information exchange.
With an emphasis on clarity of presentation throughout, the bookteaches the basic principles focusing on a mature core ofknowledge, providing students with a foundation of learning in thiscomplex and potentially confusing subject. It also addresses theissue of variation in the numbering of key amino acids as well asfeaturing interaction with RasMol software, and exercises to aidunderstanding.An accessible introduction to the complex field of cellsignallingInteracts with RasMol software – freely downloadable forviewing structures in 3DIncludes exercises and clear instructions in the use ofRasMolWell illustrated in full colour throughout
Structure and Function in Cell Signalling is aninvaluable resource to students across a range of life sciencedegree programmes including biochemistry, cell and molecularbiology, physiology, biomedicine and oncology. This book provides aclear, accessible introduction to this rapidly expanding field.
Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients.Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogenProvides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosisOffers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists
* A summary of the foods most association with human infections
* A discussion of the principles of laboratory detection of the agent considering the advantages and disadvantages of various procedure
* A 'historical to present-day' section
* A description of the infection in humans and animals, including reservoirs and the mode of transmission
Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation?
Using first-hand experience at the cutting edge of science, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge illustrates one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe.
Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden describe the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.
– Winner, Stephen Hawking Medal for Science Communication
*A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab
*Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates
*More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates
*Includes entirely new chapters on the latest areas in the field of bioconjugation as follows:
Microparticles and nanoparticles
Silane coupling agents
Dendrimers and dendrons
Discrete PEG compounds
Buckyballs,fullerenes, and carbon nanotubes
Mass tags and isotope tags
Bioconjugation in the study of protein interactions
Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges.Learn the fundamentals of biodesign and DNA engineeringExplore important ethical issues raised by examples of synthetic biologyInvestigate the BioBuilder labs that probe the design-build-test cycleTest synthetic living systems designed and built by engineersMeasure several variants of an enzyme-generating genetic circuitModel "bacterial photography" that changes a strain’s light sensitivityBuild living systems to produce purple or green pigmentOptimize baker’s yeast to produce ?-carotene
Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before.
In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility.
Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging.
Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell’s ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body’s trillions of cells.
But some of our cells don’t age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young.
The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade.
The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.
The latest developments in the field are included and keyconcepts introduced in a user-friendly way to ensure that studentsare able to grasp the essentials before moving on to more advancedstudy and analysis of proteins.
An invaluable resource for students of Biochemistry, MolecularBiology, Medicine and Chemistry providing a modern approach to thesubject of Proteins.
In this subject area, practical experience is the key tolearning and this textbook provides examples and techniques to helpthe student get the best out of their projects. Design andDevelopment of Biological, Chemical, Food and Pharma Products aimsto aid students in developing good working habits for productdevelopment. Students are challenged with examples of real problemsthat they might encounter as engineers.
Written in an informal, student-friendly tone, this unique bookincludes examples of real products and experiences from realcompanies to bring the subject alive for the student as well asplacing emphasis on problem solving and team learning to set afoundation for a future in industry. The book includes anintroduction to the subject of Colloid Science, which is importantin product development, but neglected in many curricula. Knowledgeof engineering calculus and basic physical chemistry as well asbasic inorganic and organic chemistry are assumed.
An invaluable text for students of product design in chemicalengineering, biochemistry, biotechnology, pharmaceutical sciencesand product development.Uses many examples and case studies drawn from a range ofindustries.Approaches product development as a subject in its own rightrather than a sideline of process engineeringEmphasizes a problem solving and team learning approach.Assumes some knowledge of calculus, basic physical chemistryand basic transport phenomena as well as some inorganic and organicchemistry.
* Offers almost a 20% expansion over the first edition
* Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic
* Neal Nathanson is one of the primary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virology and Topley and Wilson's Microbiology
* Now in four color throughout!
The book is professionally illustrated in four color throughout with beautiful artwork which by itself distinguish the title from any comparable title.
Adopting a modern approach and with extensive use of clearcomprehensive diagrams, Essential Microbiology explains keytopics through the use of definition boxes and end of chapterquestions.
This book is invaluable for undergraduate students in thebiological, food and health sciences taking a first course inMicrobiology.comprehensive introduction covering all aspects of thisexciting subject.includes numerous examples and applications from a wide rangeof fields.definition boxes, key points and self-test questions enhancestudent understanding.
All of the core bioscience laboratory techniques are coveredincluding: basic calculations and the preparation of solutions;aseptic techniques; microscopy techniques; cell fractionation ;spectrophotometry; chromatography of small and large molecules:electrophoresis of proteins and nucleic acids and data analysis. Inaddition the book includes clear, relevant diagrams and workedexamples of calculations.
In short, this is a 'must-have' for all first year biosciencestudents struggling to get to grips with this vitally importantelement of their course.