Just two months before the September 11 terrorist attacks, Dr. Judy Melinek began her training as a New York City forensic pathologist. While her husband and their toddler held down the home front, Judy threw herself into the fascinating world of death investigation—performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy’s two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines Flight 587.
An unvarnished portrait of the daily life of medical examiners—complete with grisly anecdotes, chilling crime scenes, and a welcome dose of gallows humor—Working Stiff offers a glimpse into the daily life of one of America’s most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies—and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on television to reveal the secret story of the real morgue. “Haunting and illuminating...the stories from her average workdays…transfix the reader with their demonstration that medical science can diagnose and console long after the heartbeat stops” (The New York Times).
the drama of the front lines.”
-Richard Danzig, former secretary of the navy
The first major bioterror event in the United States-the anthrax attacks in October 2001-was a clarion call for scientists who work with “hot” agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.
Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.
Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.
Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.
Every brain begins as a female brain. It only becomes male eight weeks after conception, when excess testosterone shrinks the communications center, reduces the hearing cortex, and makes the part of the brain that processes sex twice as large.
Louann Brizendine, M.D. is a pioneering neuropsychiatrist who brings together the latest findings to show how the unique structure of the female brain determines how women think, what they value, how they communicate, and whom they’ll love. Brizendine reveals the neurological explanations behind why
• A woman remembers fights that a man insists never happened
• A teen girl is so obsessed with her looks and talking on the phone
• Thoughts about sex enter a woman’s brain once every couple of days but enter a man’s brain about once every minute
• A woman knows what people are feeling, while a man can’t spot an emotion unless somebody cries or threatens bodily harm
• A woman over 50 is more likely to initiate divorce than a man
Women will come away from this book knowing that they have a lean, mean communicating machine. Men will develop a serious case of brain envy.
Presents information in a concise, at-a-glance format.
Fits into your pocket, for a convenient reference any time.
Offers abundant page references to the parent text, making additional information easy to find.Completely updated to reflect the latest knowledge and techniques across all areas of pathology.
Why do you fall in love with one person rather than another? In this fascinating and informative book, Helen Fisher, one of the world's leading experts on romantic love, unlocks the hidden code of desire and attachment. Each of us, it turns out, primarily expresses one of four broad personality types—Explorer, Builder, Director, or Negotiator—and each of these types is governed by different chemical systems in the brain. Driven by this biology, we are attracted to partners who both mirror and complement our own personality type.
Until now the search for love has been blind, but Fisher pulls back the curtain and reveals how we unconsciously go about finding the right match. Drawing on her unique study of 40,000 men and women, she explores each personality type in detail and shows you how to identify your own type. Then she explains why some types match up well, whereas others are problematic. (Note to Explorers: be prepared for a wild ride when you hitch your star to a fellow Explorer!) Ultimately, Fisher's investigation into the complex nature of romance and attachment leads to astonishing new insights into the essence of dating, love, and marriage.
Based on entirely new research—including a detailed questionnaire completed by seven million people in thirty-three countries—Why Him? Why Her? will change your understanding of why you love him (or her) and help you use nature's chemistry to find and keep your life partner.
Lange Pathology Flash Cards, Third EditionComplete coverage of all major topics covered in medical school pathology courses Each disease-specific card features a clinical vignette and details of the disorder, including: Etiology and epidemiology Pathologic or histologic findings Classic clinical presentations Current medical treatments Perfect for disease comparisons
Efficiently review a wide spectrum of topicswith page references and a parallel organization to both Robbins and Cotran Pathologic Basis of Disease and Robbins Basic Pathology, making additional information easy to locate.
Reinforce your understanding of key contentwith answers and detailed explanations for every question at the end of each chapter.
Enhance your understanding of pathophysiology and integrate pathologywith other medical disciplines by examining correlative laboratory, radiologic, and physical diagnostic data.
Visualize key pathologic concepts and conditionsand test your diagnostic skills with over 1,100 full-color images. Features new questions that reflect today’s hot topics in pathology, keeping you up to date. Includes many new illustrations to enhance visual guidance. Uses a new chapter arrangement to conform to the new Table of Contents in Robbins and Cotran Pathologic Basis of Disease, 8th Edition, for easier cross referencing.
The AJCC Cancer Staging Atlas, 2nd Edition, is an official publication of the American Joint Committee on Cancer, the recognized international leader in state-of-the-art information on cancer staging. This Atlas has been created as a companion to the updated 7th Edition of the AJCC Cancer Staging Manual, which continues to disseminate the importance of anatomical and pathological staging in the management of cancer. This state-of-the-art, invaluable 2nd Edition includes a CD containing PowerPoint slides of all illustrations, additional color, and a user-friendly, easy-to-read layout. The AJCC Cancer Staging Atlas, 2nd Edition will serve as an indispensable reference for clinicians, registrars, students, trainees, and patients.
Grasp the connections between basic science and clinical medicine with clinicopathologic correlations throughout.Learn core concepts quickly and efficiently with a highly templated design that highlights pathogenesis and morphology.
Artwork revised and updated for a more modern look and more three-dimensional feel
Targeted Therapy boxes – provides clinical information on appropriate therapy related to the disease under discussion
All photomicrographs and gross photos reviewed and improved to ensure excellent quality
Designed to complement Robbins and Cotran Pathologic Basis of Disease, 8th Edition and Robbins Basic Pathology, 8th Edition, this full-color atlas offers more than 1,500 outstanding full-color illustrations that vividly depict the diseases you need to know for pathology courses and USMLE exams. A quick visual reference or review of material for students and professionals alike.Includes gross, microscopic, and radiologic images correlated with examples of normal organs and tissues for comparison.Extensive legends summarize the key information you need to know.Correlates pathology with clinical history, physical exam findings, and clinical laboratory tests.A perfect study complement to Robbins and Cotran Review of Pathology. Includes many new and improved images.
Visually grasp and retain difficult concepts easilythanks to a user-friendly color-coded format, key concept boxes, explanatory diagrams, and over 190 photos to help you visualize tissues and diseases.
Put concepts into practice. "Critical Thinking Boxes" and 25 online cases encourage you to "think immunologically" while anchoring your understanding of immunology through clinical application.
Gauge your mastery of the materialand build confidence with high-yield style chapter-opening summaries and case-based and USMLE-style questions that provide effective chapter review and quick practice for your exams.
Access the full contents online at www.studentconsult.comwhere you'll find the complete text and illustrations, USMLE-style questions, clinical cases, and much more! Get the depth of coverage you need in a smaller, more manageably sized book. Through meticulous editing and reorganization, primary material remains in the book while more specialized and clinical material has been moved online.
Master the most cutting-edge concepts in immunology.Thorough updates throughout provide the timely knowledge you need ace your exams.
Forensic Science Under Siege is the first book to integrate and explain these problematic trends in forensic science. The issues are timely, and are approached from an investigatory, yet scholarly and research-driven, perspective. Leading experts are consulted and interviewed, including directors of highly visible forensic laboratories, as well as medical examiners and coroners who are commandeering the discussions related to these issues. Interviewees include Henry Lee, Richard Saferstein, Cyril Wecht, and many others.
The ultimate consequences of all these pressures, as well as the future of forensic science, has yet to be determined. This book examines these challenges, while also exploring possible solutions (such as the formation of a forensic science consortium to address specific legislative issues). It is a must-read for all forensic scientists.Provides insight on the current state of forensic science, demands, and future direction as provided by leading experts in the fieldConsolidates the current state of standards and best-practices of labs across disciplinesDiscusses a controversial topic that must be addressed for political support and financial funding of forensic science to improve
This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention.
The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.
Thoroughly revised and up-dated edition of the standard reference work in histotechnology that successfully integrates both theory and practice.Provides a single comprehensive resource on the tried and tested investigative techniques as well as coverage of the latest technical developments.
Over 30 international expert contributors all of whom are involved in teaching, research and practice.Provides authoritative guidance on principles and practice of fixation and staining.
Extensive use of summary tables, charts and boxes.Information is well set out and easy to retrieve.
Six useful appendices included (SI units, solution preparation, specimen mounting, solubility). Provides practical information on measurements, preparation solutions that are used in daily laboratory practice.
Color photomicrographs used extensively throughout. Better replicates the actual appearance of the specimen under the microscope.
Brand new co-editors.
New material on immunohistochemical and molecular diagnostic techniques.Enables user to keep abreast of latest advances in the field.
This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Third Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants are fully explored. Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter.
Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Third Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.
You'll never find an easier, more efficient, and more focused way to ace pathology and pathology-related questions on the USMLE and course examinations than USMLE Road Map. Designed to provide maximum learning in minimum time this unique review offers a concise, creative, and well-illustrated new approach to mastering pathology.
FeaturesUSMLE Shortcuts for effective USMLE preparation Outline Format with a two-color presentation guides you through the most important areas in pathology Hi-Yield Facts promote comprehension and recall Over 90 Images , including photomicrographs and clinical pictures Rapid Review Glossary defines common terms, diseases, signs, syndromes, and bodies Learning tips and tricks garnered from years of interaction with students just like you Clear explanations from instructors with the experience to know the questions you would ask
Nessa Carey, a leading epigenetics researcher, connects the field’s arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.
Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.
The book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field.Provides an understanding of the theoretical principles important for biological NMR spectroscopyDemonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experimentsAllows for the capability of designing effective experimental protocols for investigations of protein structures and dynamicsIncludes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods
Dail and Hammar’s Pulmonary Pathology has set the standard for which all other pathology texts strive to achieve. From stellar reviews of the Second Edition:
"When the first edition of Pulmonary Pathology by David H. Dail and Samuel P. Hammar was published in 1988, it was clear that it was to become the reference book for pulmonary pathology. It was difficult to conceive then that a better book on the subject could be assembled. The second edition of this encyclopedic work proved convincingly that improvement could occur. Indeed, the new revised edition is more complete and better illustrated...I consider this book to be an outstanding contribution to the pathology literature and a must in the library of surgical and pulmonary pathologists." -- Human Pathology
Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Fourth Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.
Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word “gene” and has engendered a bitter battle over whether or not this genomic “nonsense” is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey’s book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field.
Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion—mitochondria and bioenergetics. This legendary saga began over two billion years ago, when one bacterium entered another without being digested, ultimately creating the first mitochondrion.
Since then, for life to exist beyond single-celled bacteria, it’s the mitochondria that are responsible for this life-giving energy. Yet, current research has also revealed a dark side; many seemingly unconnected degenerative diseases have their roots in dysfunctional mitochondria. Modern research, however, has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. By reading this book, you are about to dive into this epic story, and learn how to add years to your life, and life to your years.
• Features more than 150 tables that examine the interpretation of histochemical stains, immunohistochemical studies, electron microscopy findings, cytogenetic changes, and much more.
• Presents a user-friendly design, concise paragraphs, numbered lists, and bulleted material throughout the text that makes information easy to find.
• Offers detailed instructions on the dissection, description, and sampling of specimens.
• Includes useful guidance on operating room consultations, safety, microscope use, and error prevention.
• Explains the application of pathology reports to patient management.
• Discusses how to avoid frequent errors and pitfalls in pathology specimen processing.
• Includes all updates from the last three revisions of the Brigham & Women's Hospital in-house handbook, ensuring you have the best knowledge available.
• Features new and updated tables in special studies sections, particularly immunohistochemistry with an increased number of antibodies covered, keeping you absolutely up to date.
• Provides new tables that cover the histologic appearance of viruses and fungi and a table covering the optical properties of commonly seen noncellular material for easy reference.
• Incorporates the TNM classification systems from the new 7th edition AJCC manual, including additional guidelines for the assessment of critical pathologic features.
• Presents four new full size illustrations by Dr. Christopher French and Mr. Shogun G. Curtis, as well as 39 illustrations for the new tables on viruses, fungi, and noncellular material to aid in their recognition.