Reviews of the First Edition
“For anyone wishing to know what really goes on in theirNMR experiments, I would highly recommend this book” –Chemistry World
“…I warmly recommend for budding NMRspectroscopists, or others who wish to deepen their understandingof elementary NMR theory or theoretical tools” –Magnetic Resonance in Chemistry
Organic Structures from Spectra, Fifth Edition is acarefully chosen set of more than 280 structural problems employingthe major modern spectroscopic techniques, a selection of 27problems using 2D-NMR spectroscopy, more than 20 problemsspecifically dealing with the interpretation of spin-spin couplingin proton NMR spectra and 8 problems based on the quantitativeanalysis of mixtures using proton and carbon NMRspectroscopy. All of the problems are graded to develop andconsolidate the student’s understanding of organicspectroscopy. The accompanying text is descriptive and onlyexplains the underlying theory at a level which is sufficient totackle the problems. The text includes condensed tables ofcharacteristic spectral properties covering the frequentlyencountered functional groups.
The examples themselves have been selected to include allimportant common structural features found in organic compounds andto emphasise connectivity arguments. Many of the compoundswere synthesised specifically for this purpose. There aremany more easy problems, to build confidence and demonstrate basicprinciples, than in other collections.
The fifth edition of this popular textbook:
• includes more than 250 new spectra and more than 25completely new problems;
• now incorporates an expanded suite of new problemsdealing with the analysis of 2D NMR spectra (COSY, C H Correlationspectroscopy, HMBC, NOESY and TOCSY);
• has been expanded and updated to reflect the newdevelopments in NMR and to retire older techniques that are nolonger in common use;
• provides a set of problems dealing specifically withthe quantitative analysis of mixtures using NMR spectroscopy;
• features proton NMR spectra obtained at 200, 400 and600 MHz and 13C NMR spectra include DEPT experiments as well asproton-coupled experiments;
• contains 6 problems in the style of the experimentalsection of a research paper and two examples of fully workedsolutions.
Organic Structures from Spectra, Fifth Edition will proveinvaluable for students of Chemistry, Pharmacy and Biochemistrytaking a first course in Organic Chemistry.
Nuclear Magnetic Resonance Spectroscopy
Reviews from earlier editions
“Your book is becoming one of the “go to”books for teaching structure determination here in theStates. Great work!”
“…I would definitely state that this book is themost useful aid to basic organic spectroscopy teaching in existenceand I would strongly recommend every instructor in this area to useit either as a source of examples or as a classtextbook”.
Magnetic Resonance in Chemistry
“Over the past year I have trained many students usingproblems in your book - they initially find it as a task. Butafter doing 3-4 problems with all their brains activities...working out the rest of the problems become a mania. They getaddicted to the problem solving and every time they solve a problemby themselves, their confident level also increases.”
“I am teaching the fundamentals of MolecularSpectroscopy and your books represent excellent sources ofspectroscopic problems for students.”
This new edition has been thoroughly revised and updated and hasbeen redesigned to give the book a more contemporary look. As withprevious editions it contains numerous examples, references and aseries of exercises of increasing difficulty to encourage studentunderstanding. Updates include: Increased coverage of MALDI andESI, more detailed description of time of flight spectrometers, newmaterial on isotope ratio mass spectrometry, and an expanded rangeof applications.
Mass Spectrometry, Third Edition is an invaluableresource for all undergraduate and postgraduate students using thistechnique in departments of chemistry, biochemistry, medicine,pharmacology, agriculture, material science and food science. It isalso of interest for researchers looking for an overview of thelatest techniques and developments.
Additional topics include basic instrumental components and sampling techniques, quantitative analysis, Raman polarization data, infrared gas contours, and polarized IR studies, among others.Focuses on group frequency correlations and how to use them in spectral interpretationRevised and updated by a pioneer in the field, Norman Colthup, who for thirty years has served as an expert lecturer for the Fisk Infrared InstituteExplores new group frequency studies in aromatics, alkanes and olefins, among othersIncludes completely updated section on instrumentation
This book incorporates recent technological advances in analytical pyrolysis methods especially useful for the characterization of 163 typical synthetic polymers. The book briefly reviews the instrumentation available in advanced analytical pyrolysis, and offers guidance to perform effectually this technique combining with gas chromatography and mass spectrometry. Main contents are comprehensive sample pyrograms, thermograms, identification tables, and representative mass spectra (MS) of pyrolyzates for synthetic polymers. This edition also highlights thermally-assisted hydrolysis and methylation technique effectively applied to 33 basic condensation polymers.Coverage of Py-GC/MS data of conventional pyrograms and thermograms of basic 163 kinds of synthetic polymers together with MS and retention index data for pyrolyzates, enabling a quick identificationAdditional coverage of the pyrograms and their related data for 33 basic condensation polymers obtained by the thermally-assisted hydrolysis and methylation techniqueAll compiled data measured under the same experimental conditions for pyrolysis, gas chromatography and mass spectrometry to facilitate peak identificationSurveyable instant information on two facing pages dedicated to the whole data of a given polymer sample
The section regarding GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types has the same number of compound types as the original edition, but the information in each section has been expanded to not only explain some of the spectra but to also explain why certain fragmentations take place. The number of Appendices has been increased from 12 to 17. The Appendix on Atomic Masses and Isotope Abundances has been expanded to provide tools to aid in determination of elemental composition from isotope peak intensity ratios. An appendix with examples on "Steps to follow in the determination of elemental compositions based on isotope peak intensities" has been added. Appendices on whether to use GC/MS or LC/MS, third-party software for use in data analysis, list of information required in reporting GC/MS data, X+1 and X+2 peak relative intensities based on the number of atoms of carbon in an ion, and list of available EI mass spectral databases have been added. Others such as the ones on derivatization, isotope peak patterns for ions with Cl and/or Br, terms used in GC and in mass spectrometry, and tips on setting up, maintaining and troubleshooting a GC/MS system have all been expanded and updated.Covers the practical instruction necessary for successful operation of GC/MS equipmentReviews the latest advances in instrumentation, ionization methods, and quantitationIncludes troubleshooting techniques and a variety of additional information useful for the GC/MS practitionerA true benchtop referenceA guide to a basic understanding of the components of a Gas Chromatograph-Mass Spectrometer (GC-MS)Quick References to data interpretationReady source for information on new analyses
Students in the physical and life sciences, and in engineering, need to know about the physics and biology of light. Recently, it has become increasingly clear that an understanding of the quantum nature of light is essential, both for the latest imaging technologies and to advance our knowledge of fundamental life processes, such as photosynthesis and human vision. From Photon to Neuron provides undergraduates with an accessible introduction to the physics of light and offers a unified view of a broad range of optical and biological phenomena. Along the way, this richly illustrated textbook builds the necessary background in neuroscience, photochemistry, and other disciplines, with applications to optogenetics, superresolution microscopy, the single-photon response of individual photoreceptor cells, and more.
With its integrated approach, From Photon to Neuron can be used as the basis for interdisciplinary courses in physics, biophysics, sensory neuroscience, biophotonics, bioengineering, or nanotechnology. The goal is always for students to gain the fluency needed to derive every result for themselves, so the book includes a wealth of exercises, including many that guide students to create computer-based solutions. Supplementary online materials include real experimental data to use with the exercises.
Assumes familiarity with first-year undergraduate physics and the corresponding math
Overlaps the goals of the MCAT, which now includes data-based and statistical reasoning
Advanced chapters and sections also make the book suitable for graduate courses
An Instructor's Guide and illustration package is available to professors
In the expanded second edition of Practical Guide and Spectral Atlas for Interpretive Near-Infrared Spectroscopy, the authors include new research, editorials, supplements, and molecular structural formulas, along with updated references and information on NIR spectra. The thoroughly updated and revised second edition offers a full library of color spectra in a larger format to ensure clarity and reader comprehension.
Providing a rich set of reference information required to interpret NIR spectra for research and industrial applications, this book:
Offers more than 300 figures representing all the major functional groups and their NIR frequency ranges Contains over 120 pages of tables and charts illustrating overlapping spectra Covers NIR spectra for organic compounds, including alkanes, carboxylic acids, amines, dienes, alkynes, heterocyclic compounds, amino acids, and aldehydes Provides comprehensive appendices with spectra-structure correlations, example spectra, and other useful data for interpreting NIR spectra
The book assumes only a basic knowledge of complex numbers andmatrices, and provides the reader with numerous worked examples andexercises to encourage understanding. With the explicit aim ofcarefully developing the subject from the beginning, the textstarts with coverage of quarks and nucleons and progresses throughto a detailed explanation of several important NMR experiments,including NMR imaging, COSY, NOESY and TROSY.
Completely revised and updated, the Second Edition features newmaterial on the properties and distributions of isotopes, chemicalshift anisotropy and quadrupolar interactions, Pake patterns, spinechoes, slice selection in NMR imaging, and a complete new chapteron the NMR spectroscopy of quadrupolar nuclei. New appendices havebeen included on Euler angles, and coherence selection by fieldgradients. As in the first edition, all material is heavilysupported by graphics, much of which is new to thisedition.
Written for undergraduates and postgraduate students taking afirst course in NMR spectroscopy and for those needing anup-to-date account of the subject, this multi-disciplinary bookwill appeal to chemical, physical, material, life, medical, earthand environmental scientists. The detailed physical insights willalso make the book of interest for experienced spectroscopists andNMR researchers.
• An accessible and carefully written introduction,designed to help students to fully understand this complex anddynamic subject
• Takes a multi-disciplinary approach, focusing on basicprinciples and concepts rather than the more practical aspects
• Presents a strong pedagogical approach throughout, withemphasis placed on individual spins to aid understanding
• Includes numerous worked examples, problems, furtherreading and additional notes
Praise from the reviews of the First Edition:
"This is an excellent book... that many teachers of NMRspectroscopy will cherish... It deserves to be a‘classic’ among NMR spectroscopy texts." NMRIN BIOMEDICINE
"I strongly recommend this book to everyone…it isprobably the best modern comprehensive description of thesubject." ANGEWANDTE CHEMIE, INTERNATIONAL EDITION
This multi-disciplined text covers the fundamentals as well asrecent advance in this topic, providing need-to-know informationfor researchers in many disciplines including pharmaceutical,environmental and biomedical analysis who are utilizing massspectrometry
In this book, you will learn the fundamental principles underpinning molecular spectroscopy and the connections between those principles and the design of spectrophotometers.
Spectroscopy, along with chromatography, mass spectrometry, and electrochemistry, is an important and widely-used analytical technique. Applications of spectroscopy include air quality monitoring, compound identification, and the analysis of paintings and culturally important artifacts. This book introduces students to the fundamentals of molecular spectroscopy – including UV-visible, infrared, fluorescence, and Raman spectroscopy – in an approachable and comprehensive way. It goes beyond the basics of the subject and provides a detailed look at the interplay between theory and practice, making it ideal for courses in quantitative analysis, instrumental analysis, and biochemistry, as well as courses focused solely on spectroscopy. It is also a valuable resource for practitioners working in laboratories who regularly perform spectroscopic analyses.
Spectroscopy: Principles and Instrumentation:Provides extensive coverage of principles, instrumentation, and applications of molecular spectroscopyFacilitates a modular approach to teaching and learning about chemical instrumentationHelps students visualize the effects that electromagnetic radiation in different regions of the spectrum has on matterConnects the fundamental theory of the effects of electromagnetic radiation on matter to the design and use of spectrophotometersFeatures numerous figures and diagrams to facilitate learningIncludes several worked examples and companion exercises throughout each chapter so that readers can check their understandingOffers numerous problems at the end of each chapter to allow readers to apply what they have learnedIncludes case studies that illustrate how spectroscopy is used in practice, including analyzing works of art, studying the kinetics of enzymatic reactions, detecting explosives, and determining the DNA sequence of the human genomeComplements Chromatography: Principles and Instrumentation
The book is divided into five chapters that cover the Fundamentals of Spectroscopy, UV-visible Spectroscopy, Fluorescence/Luminescence Spectroscopy, Infrared Spectroscopy, and Raman Spectroscopy. Each chapter details the theory upon which the specific techniques are based, provides ways for readers to visualize the molecular-level effects of electromagnetic radiation on matter, describes the design and components of spectrophotometers, discusses applications of each type of spectroscopy, and includes case studies that illustrate specific applications of spectroscopy.
Each chapter is divided into multiple sections using headings and subheadings, making it easy for readers to work through the book and to find specific information relevant to their interests. Numerous figures, exercises, worked examples, and end-of-chapter problems reinforce important concepts and facilitate learning.
Spectroscopy: Principles and Instrumentation is an excellent text that prepares undergraduate students and practitioners to operate in modern laboratories.
Andreas Manz received the 2015 Inventor Award for "Lifetime Achievement" from the European Patent Office.
Petra S Dittrich will be presented with the Heinrich-Emanuel-Merck Award 2015 at EuroAnalysis2015 Conference.
Emphasizing practical applications and real-world case studies, Materials Characterization Techniques presents the principles of widely used, advanced surface and structural characterization techniques for quality assurance, contamination control, and process improvement.
This useful volume:
Explores scientific processes to characterize materials using modern technologies Provides analysis of materials’ performance under specific use conditions Focuses on the interrelationships and interdependence between processing, structure, properties, and performance Details the sophisticated instruments involved in an interdisciplinary approach to understanding the wide range of mutually interacting processes, mechanisms, and materials Covers electron, X-ray-photoelectron, and UV spectroscopy; scanning-electron, atomic-force, transmission-electron, and laser-confocal-scanning-florescent microscopy, and gel electrophoresis chromatography Presents the fundamentals of vacuum, as well as X-ray diffraction principles
Explaining appropriate uses and related technical requirements for characterization techniques, the authors omit lengthy and often intimidating derivations and formulations. Instead, they emphasize useful basic principles and applications of modern technologies used to characterize engineering materials, helping readers grasp micro- and nanoscale properties. This text will serve as a valuable guide for scientists and engineers involved in characterization and also as a powerful introduction to the field for advanced undergraduate and graduate students.
important for determining the 3D-structure of molecules.
This new edition of the popular classic has a clear style and a highly practical, mostly non-mathematical approach. Many examples are taken from organic and organometallic chemistry, making this book an invaluable guide to undergraduate and graduate students of organic chemistry, biochemistry, spectroscopy or physical chemistry, and to researchers using this well-established and extremely important technique. Problems and solutions are included.
The possible applications of enzymes are enormous. Years of development have seen many enzymes brought onto the market, but they are still expensive to use. Therefore, their efficient application is a prerequisite for common usage. One of the main factors for this efficiency is the stability of the enzymes. The topics thus ranged from the extensive fundamental thermodynamic knowledge gathered in academic research to the practical applied knowledge built up in industry during the time that enzymes have been produced commercially.
The subject Stability and Stabilization of Enzymes was discussed from various points of view, as was reflected in the themes of the symposium sessions. In the session on Fundamentals of Enzyme Stabilisation the thermodynamic background of the phenomenon was highlighted. In yet another session, the recently developed analytical tools to measure enzyme stability and stabilisation were discussed. Further sessions comprised the physical, chemical and biological ways to obtain enzyme stabilisation and finally, the industrial practice of enzyme stabilisation was treated by representatives of the world's most important enzyme producers. The book will be of interest to researchers in universities and industry in the fields of biochemistry, enzymology and biotechnology.
Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow.
This important text is the vital resource that:Offers a reference book in the field of heating and cooling of tissue, and associated damage.Provides a comprehensive theoretical and experimental basis with biomedical applicationsShows how to develop and implement both, simple and complex mathematical models to predict tissue temperaturesIncludes simple examples and results so readers can use those results directly or adapt them for their applications
Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.
Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.
Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.
The book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field.Provides an understanding of the theoretical principles important for biological NMR spectroscopyDemonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experimentsAllows for the capability of designing effective experimental protocols for investigations of protein structures and dynamicsIncludes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods
Designed for those new to FTIR, but with enough reference material to appeal to journeyman and expert spectroscopists, this book does not demand any extensive familiarity with chemistry or physics. Specializing in concise and comprehensible explanations of FTIR topics, the author introduces the field of infrared spectroscopy, including the strengths and weaknesses of FTIR as a chemical analysis technique. He then describes the instrument itself and explores topics such as how an interferometer generates a spectrum, optimization of spectral quality, and which tests are used to monitor instrument health.
The book discusses how to properly use spectral processing to increase the information of a spectrum without damaging the data and takes considerable care in instructing on sample preparation, as good sample preparation constitutes half the battle in extracting good data. The final chapters examine single analyte quantitative analysis and conclude with an overview of infrared microscopy.
Drawing on the experience and knowledge of the author as both a professor and practitioner, Fundamentals of Fourier Transform Infrared Spectroscopy offers up-to-date information given in clear, easily understood language to appeal to beginner and expert spectroscopists alike. The author maintains a website and blog with supplemental material. His training course schedule is also available online.
This book guides the reader through the mathematics, physics and practical techniques needed to use telescopes (from small amateur models to the larger instruments installed in many colleges) and to observe objects in the sky. Mathematics to around Advanced Placement standard (US) or A level (UK) is assumed, although High School Diploma (US) or GCSE-level (UK) mathematics plus some basic trigonometry will suffice most of the time. Most of the physics and engineering involved is described fully and requires no prior knowledge or experience.
This is a ‘how to’ book that provides the knowledge and background required to understand how and why telescopes work. Equipped with the techniques discussed in this book, the observer will be able to operate with confidence his or her telescope and to optimize its performance for a particular purpose. In principle the observer could calculate his or her own predictions of planetary positions (ephemerides), but more realistically the observer will be able to understand the published data lists properly instead of just treating them as ‘recipes.’ When the observer has obtained measurements, he/she will be able to analyze them in a scientific manner and to understand the significance and meaning of the results.
“Telescopes and Techniques, 3rd Edition” fills a niche at the start of an undergraduate astronomer’s university studies, as shown by it having been widely adopted as a set textbook. This third edition is now needed to update its material with the many new observing developments and study areas that have come into prominence since it was published. The book concentrates on the knowledge needed to understand how small(ish) optical telescopes function, their main designs and how to set them up, plus introducing the reader to the many ways in which objects in the sky change their positions and how they may be observed. Both visual and electronic imaging techniques are covered, together with an introduction to how data (measurements) should be processed and analyzed. A simple introduction to radio telescopes is also included. Brief coverage of the most advanced topics of photometry and spectroscopy are included, but mainly to enable the reader to see some of the developments possible from the basic observing techniques covered in the main parts of the book.
On the threshold of the new millennium when plasma emission and mass spectrometry are so important and popular, the editor considered it timely to produce a book which covers all present atomic detectors and techniques where FA has been or can be advantageously employed. The book has been conceived in three separate parts: Part I gives the fundamental, instrumentation and potential of FIA as a most versatile sample presentation/introduction system for atomic spectrometry. Part II provides a modern account of fundamentals, possibilities and applications offered by flow analysis to atomic spectrometry for on-line sample pretreatments, separations and preconcentrations. Part III deals with applications of FA-ASD combinations to analytical problem-solving in most varied fields and situations.
This monograph integrates the most popular aspects of FIA, its new developments for sample on-line treatments and on-line non-chromatographic and chromatographic separations (all typical 'flow analysis') in connection with all branches of analytical atomic spectrometry. Thus, academics, researchers and routine users of analytical atomic spectrometry will find this book invaluable.
Fully revised and expanded by 30%, X-Ray Fluorescence Spectrometry,Second Edition incorporates the latest industrial and scientifictrends in all areas. It updates all previous material and adds newchapters on such topics as the history of X-ray fluorescencespectroscopy, the design of X-ray spectrometers, state-of-the-artapplications, and X-ray spectra.
Ron Jenkins draws on his extensive experience in training andconsulting industry professionals for this clear and concisetreatment, covering first the basic aspects of X rays, then themethodology of X-ray fluorescence spectroscopy and availableinstrumentation. He offers a comparison between wavelength andenergy dispersive spectrometers as well as step-by-step guidelinesto X-ray spectrometric techniques for qualitative and quantitativeanalysis-from specimen preparation to real-world industrialapplication.
Favored by the American Chemical Society and the InternationalCentre for Diffraction Data, X-Ray Fluorescence Spectrometry,Second Edition is an ideal introduction for newcomers to the fieldand an invaluable reference for experienced spectroscopists-inchemical analysis, geology, metallurgy, and materialsscience.
An up-to-date review of X-ray spectroscopic techniques. This provenguidebook for industry professionals is thoroughly updated andexpanded to reflect advances in X-ray analysis over the lastdecade. X-Ray Fluorescence Spectrometry, Second Editionincludes:
* The history of X-ray fluorescence spectrometry-new to thisedition.
* A critical review of the most useful X-ray spectrometers.
* Techniques and procedures for quantitative and qualitativeanalysis.
* Modern applications and industrial trends.
* X-ray spectra-new to this edition.
Principle, experimental set ups, parameters and interpretation rules of several advanced IR-based techniques; application to biointerface characterisation through the presentation of recent examples, will be given in this book. It will describe how to characterise amino acids, protein or bacterial strain interactions with metal and oxide surfaces, by using infrared spectroscopy, in vacuum, in the air or in an aqueous medium. Results will highlight the performances and perspectives of the technique.Description of the principles, expermental setups and parameter interpretation, and the theory for several advanced IR-based techniques for interface characterisationContains examples which demonstrate the capacity, potential and limits of the IR techniquesHelps finding the most adequate mode of analysisContains examplesContains a glossary by techniques and by keywords
Infrared (IR) Spectroscopy deals with the infrared part of the electromagnetic spectrum. It measure the absorption of different IR frequencies by a sample positioned in the path of an IR beam. Currently, infrared spectroscopy is one of the most common spectroscopic techniques used in the food industry. With the rapid development in infrared spectroscopic instrumentation software and hardware, the application of this technique has expanded into many areas of food research. It has become a powerful, fast, and non-destructive tool for food quality analysis and control.
Infrared Spectroscopy for Food Quality Analysis and Control reflects this rapid technology development. The book is divided into two parts. Part I addresses principles and instruments, including theory, data treatment techniques, and infrared spectroscopy instruments. Part II covers the application of IRS in quality analysis and control for various foods including meat and meat products, fish and related products, and others.
*Explores this rapidly developing, powerful and fast non-destructive tool for food quality analysis and control
*Presented in two Parts -- Principles and Instruments, including theory, data treatment techniques, and instruments, and Application in Quality Analysis and Control for various foods making it valuable for understanding and application
*Fills a need for a comprehensive resource on this area that includes coverage of NIR and MVA
This book is an easy-to-use compendium of problems encountered when using various commonly used analytical techniques. Emphasis is on impurities, by-products, contaminants and other artifacts. A separate entry is provided for each artifact. For specific chemicals, this entry provides the common name, mass spectrum, gas chromatographic data, CAS name and registry number, synonyms and a narrative discussion. More than 1100 entries are included. Mass spectral data are indexed in a 6-peak index (molecular ion, base peak, second peak, third peak) and there are also formula, author and subject indexes. An extensive bibliography contains complete literature citations.
The book is designed to be used. It will not only allow experienced analysts to profit from the mistakes of others, but it will also be invaluable to other scientists who use analytical instruments in their work.
A discussion is then presented on carbon-13 NMR, detailing itspros and cons and showing how it can be used in conjunction withproton NMR via the pivotal 2-D techniques (HSQC and HMBC) to yieldvital structural information. Some of the more specialisttechniques available are then discussed, i.e. flow NMR, solventsuppression, Magic Angle Spinning, etc. Other important nuclei arethen discussed and useful data supplied. This is followed by adiscussion of the neglected use of NMR as a tool for quantificationand new techniques for this explained. The book then considers thesafety aspects of NMR spectroscopy, reviewing NMR software forspectral prediction and data handling and concludes with a set ofworked Q&As.
High-Resolution XAS/XES: Analyzing Electronic Structures of Catalystscovers the latest developments in X-ray light sources, detectors, crystal spectrometers, and photon-in-photon-out core level spectroscopy techniques. It also addresses photon-in-photon-out core level spectroscopy applications for the study of catalytic systems, highlighting hard X-ray measurements primarily due to probe high penetration, enabling in situ studies.
This first-of-its-kind book:Discusses high-resolution X-ray emission spectroscopy (XES) and X-ray absorption spectroscopy (XAS) in terms of time-resolved and surface enhancement Supplies an understanding of catalytic reactivity essential for capitalizing on core level X-ray spectroscopy at fourth-generation light sources (XFELs) Describes all spectrometers developed to perform core level X-ray spectroscopy, considering the advantages and disadvantages of each Details methods to elucidate aspects of catalysts under working conditions, such as active sites and molecule adsorption Introduces theoretical calculations of spectra and explores biological as well as heterogeneous catalysts
Complete with guidelines and warnings for the use of this type of spectroscopy, High-Resolution XAS/XES: Analyzing Electronic Structures of Catalysts provides a comprehensive overview of the current state of this exciting field.
Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing.
The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab.Provides readers with the keys to choosing, installing, and validating a mass spectrometry platformOffers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labsExplains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab
The aim of the book is twofold. Firstly, to reveal to the reader the combined use of different spectroscopic data, to facilitate an insight into the structure and conformational properties of any new piperidine derivative. Secondly, to establish a consistent link between conformation and reactivity for a variety of piperidine derivatives. Such a bridge is a key step for stereocontrol when dealing with the application of piperidine derivatives as synthetic intermediates. The book is conceived so that most of the information comes from visual inspection of the very abundant graphic material. An exhaustive subject index of more than 450 entries is also included.
New Advances And Development In Mass Spectrometry, Mass Spectrometry Applications, Mass Spectrometry In Pharmaceutical Industry, Spectroscopy, Mass Spectrometry Applications In Clinical Diagnostics, Capillary Electrophoresis, Tandem Mass Spectrometry, Environmental Analysis, Protein Mass Spectrometry, Ionization Techniques Mass Spectrometry, Forensic Analysis, Mass Spectrometry In Medicine, Imaging Mass Spectrometry, Analytical Chemistry, Molecular Mass Spectrometry
Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.
The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.
* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.
* Guides the reader from basic principles and methods to cutting edge applications.
* There is NO comparable book on the market to fill this fast growing field.
This is presented in a concise yet comprehensive manner and eachsection is prepared such that they can be read independently ofeach other, and all equations are presented using the most commonlyused units. Greater emphasis has been placed on spectralunderstanding/interpretation. For completeness sake, a descriptionof commonly used instrumentation is also presented. Finally, somecomplementary surface analytical techniques and associated conceptsare reviewed for comparative purposes in stand-alone appendixsections.
This workbook:Features exercises to help develop the student's understanding of how structures are determined from spectra and to promote the student's own interpretation of different spectra. Covers a large range of spectroscopic data, including mass spectrometry, infrared and 1H and 13C nuclear magnetic resonance, typically used in the routine analysis of small-sized organic molecules. Presents in full-color, in a workbook-friendly format the spectra for interpretation with explanations and analyses on the facing page.
Related to the workbook the authors have an online resource of the problems featured in the workbook, available at: htttp://spectros.unice.fr/ By using the print edition alongside the online spectra, students will be able to enhance their understanding of the interpretation of multiple spectra.
* Uses extensive illustrations to explain the concept of Diffusion Tensor Imaging
* Easy to understand, even without a background in physics
* Includes sections on image interpretation, experimental design and applications
The book begins with the core principles of gas chromatography and its specific uses with MS detectors. It discusses generalities of mass spectrometry, including the various types of MS detectors and insight into the vacuum necessary for efficient operation. Chapters cover the types of analyzers used in GC-MS and their functioning principles, with a focus on the commonly used quadrupolar analyzers, as well as the implementation, advantages, and limits of various modes of acquisition in GC-MS. The text also compares performance and limitations of quadrupolar analyzers.
The author includes a full chapter on quantification using GC-MS, a topic that can be puzzling for many chemists. Encouraging a critical approach to databases, he compares laboratory-made and commercial mass spectra databases, and describes a database research algorithm. The final chapter examines mass spectra interpretation, covering chemistry concepts such as inductive and mesomeric effects required to understand dissociation pathways, and presents a global strategy for mass spectra interpretation.