The easy way to take the confusion out of organic chemistry
Organic chemistry has a long-standing reputation as a difficult course. Organic Chemistry I For Dummies takes a simple approach to the topic, allowing you to grasp concepts at your own pace.
This fun, easy-to-understand guide explains the basic principles of organic chemistry in simple terms, providing insight into the language of organic chemists, the major classes of compounds, and top trouble spots. You'll also get the nuts and bolts of tackling organic chemistry problems, from knowing where to start to spotting sneaky tricks that professors like to incorporate.Refreshed example equationsNew explanations and practical examples that reflect today's teaching methodsFully worked-out organic chemistry problems
Baffled by benzines? Confused by carboxylic acids? Here's the help you need—in plain English!
Calixarene synthesis, with all its subtleties and sophistication. Forces at play in the inclusion of neutral and charged molecules by calixarenes. Theoretical analyses of calixarene properties. Dynamics and thermodynamics of calixarenes and their complexes. Nanocomposite construction based on calixarene aggregates. Calixarenes on surfaces. Analytical applications of calixarenes. Catalysis by calixarenes and their complexes. Resource recovery and waste treatment with calixarenes. New directions in calixarene chemistry. Hetero- and homo-calixarenes. Bioactive calixarenes. Coordination chemistry of calixarenes. Calixarenes in the solid state.
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Readers are guided on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions. The first five chapters deal with the structure oforganic compounds and discuss important organic chemistrybonds, fundamental principles of conformation, and stereochemistryof organic molecules, and reactive intermediates in organicchemistry. Chapters 6 to 9 are concerned with generalprinciples of mechanism in organic chemistry, including acids andbases, photochemistry, sonochemistry and microwave irradiation, andfinally the relationship between structure and reactivity. Thelast 10 chapters cover the nature and the scope of organicreactions and their mechanisms.
The 7th edition proves again it is a must-havedesktop reference and textbook for every student and professionalworking in organic chemistry or related fields.
Key features of the 7th edition:Every chapter has been updated with the most recent reactioninformation with references to both the primary and reviewliteratureNew to the 7th edition: 5,500 references since the lastedition, updates / rewrites of the retained sections, and anupdated index in Appendix BContains more than 1650 reactions and 20,000 valuablereferences to the primary literatureIncludes appendices on the literature of organic chemistry andthe classification of reactions according to the compoundssynthesizedGuides the reader on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions.
Reviews of the previous edition:
"...a favorite general organic chemistry text and an easy-to-useone-volume reference. We are confident that this book will remain adominant reference and that it will reside on many chemists'personal bookshelves." –Journal of MedicinalChemistry
"Who can hope to be seriously accepted as a member of theorganic chemistry community without being in possession of at leastone edition of 'March'?" –Chemistry and Industry
So, you survived the first semester of Organic Chemistry (maybeeven by the skin of your teeth) and now it's time to get back tothe classroom and lab! Organic Chemistry II For Dummies isan easy-to-understand reference to this often challengingsubject.
Thanks to this book, you'll get friendly and comprehensibleguidance on everything you can expect to encounter in your OrganicChemistry II course.An extension of the successful Organic Chemistry I ForDummiesCovers topics in a straightforward and effective mannerExplains concepts and terms in a fast and easy-to-understandway
Whether you're confused by composites, baffled by biomolecules,or anything in between, Organic Chemistry II For Dummiesgives you the help you need — in plain English!
Note: CD-ROM/DVD and other supplementary materials arenot included as part of eBook file.
With its balanced presentation of polymer chemistry, physics,and engineering applications, the Third Edition of this classictext continues to instill readers with a solid understanding of thecore concepts underlying polymeric materials. Both students andinstructors have praised the text for its clear explanations andlogical organization. It begins with molecular-level considerationsand then progressively builds the reader's knowledge withdiscussions of bulk properties, mechanical behavior, and processingmethods.
Following a brief introduction, Fundamental Principles ofPolymeric Materials is divided into four parts:
Part 1: Polymer Fundamentals
Part 2: Polymer Synthesis
Part 3: Polymer Properties
Part 4: Polymer Processing and Performance
Thoroughly Updated and Revised
Readers familiar with the previous edition of this text willfind that the organization and style have been updated with newmaterial to help them grasp key concepts and discover the latestscience, techniques, and applications. For example, there are newintroductory sections on organic functional groups focusing on thestructures found in condensation polymerizations. The text alsofeatures new techniques for polymer analysis, processing, andmicroencapsulation as well as emerging techniques such as atomtransfer radical polymerization.
At the end of each chapter are problems—including manythat are new to this edition—to test the reader's grasp ofcore concepts as they advance through the text. There are alsoreferences leading to the primary literature for furtherinvestigation of individual topics.
A classic in its field, this text enables students in chemistry,chemical engineering, materials science, and mechanical engineeringto fully grasp and apply the fundamentals of polymeric materials,preparing them for more advanced coursework.
This is a revised edition of a very successful book, which appeals to both academic and industrial markets.Illustrates the organic mechanism associated with each enzyme-catalyzed reactionMakes the connection between organic reaction mechanisms and enzyme mechanismsCompiles the latest information about molecular mechanisms of enzyme reactionsAccompanied by clearly drawn structures, schemes, and figuresIncludes an extensive bibliography on enzyme mechanisms covering the last 30 yearsExplains how enzymes can accelerate the rates of chemical reactions with high specificityProvides approaches to the design of inhibitors of enzyme-catalyzed reactionsCategorizes the cofactors that are appropriate for catalyzing different classes of reactionsShows how chemical enzyme models are used for mechanistic studiesDescribes catalytic antibody design and mechanismIncludes problem sets and solutions for each chapter Written in an informal and didactic style
The authors are careful to present new information such that it links it to existing content, ever mindful that students assimilate new information only in the proper context. The enriched assessment content in WileyPLUS Learning Space offers students the opportunity to gauge their conceptual understanding and receive immediate feedback to address misconceptions.
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This book is comprised of 11 chapters and begins with a brief overview of plasma polymerization and its growing importance for the formation of entirely new kinds of materials. The discussion then shifts to a comparison between plasma-state polymerization and plasma-induced polymerization, between plasma polymerization and graft polymerization, and between plasma polymerization and radiation polymerization. The reader is also introduced to fundamental aspects of gas-phase reactions, paying particular attention to the classical kinetic theory of gas, as well as the mechanisms of formation of polymeric materials in plasma, competitive ablation and polymer formation in plasma, and polymer deposition in plasma polymerization. The operational parameters of plasma polymerization are described and a chapter devoted to the electrical properties of plasma-polymerized thin organic films concludes the book.
This book will be of interest to students and researchers of material science.
The monograph first offers information on the processes involved in the determination of trace elements in organic matters, as well as the methods not involving complete destruction of these elements. The text surveys the sources of errors in the processes responsible in pinpointing elements in organic compounds. These processes include sampling, disruption of the samples, manipulation, and measurements.
The book examines the processes of wet and dry oxidation, including their applications to sulfuric, nitric, and perchloric acids and hydrogen peroxide. The methods of dry ashing and oxidation with excited oxygen and oxidative fusion are elaborated. The text also underscores the varying methods in removing trace elements in organic compounds. The elements include zinc, copper, silver, gold, lead, germanium, titanium, arsenic, bismuth, and vanadium. The book also describes wet digestion methods and dry ashing procedures in the removal of trace elements in organic matters.
The monograph is a vital source of information for readers interested in the identification of trace elements in organic compounds.
Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation.
The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip.
This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry.
Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing. www.immunoassayhandbook.com is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book.
David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing.Provides a unique mix of theory, practical advice and applications, with numerous examplesOffers explanations of technologies under development and practical insider tips that are sometimes omitted from scientific papers Includes a comprehensive troubleshooting guide, useful for solving problems and improving assay performanceeProvides valuable chapter updates, now available on www.immunoassayhandbook.com
Faraday titled the lectures "The Chemical History of a Candle," choosing the subject because, as he explained, "There is not a law under which any part of this universe is governed which does not come into play and is not touched upon [during the time a candle burns]."
That statement is the foundation for a book that describes, with great clarity, the components, function and weight of the atmosphere; the function of a candle wick; capillary attraction; the carbon content in oxygen and living bodies; the production of carbon dioxide from coal gas and sugar; the properties of carbonic acid; respiration and its analogy to the burning of a candle; and much more. There is also a chapter comprising Faraday's "Lecture on Platinum."
A useful classroom teaching tool, this classic text will also appeal to a wide audience interested in scientific inquiry.
Second Edition highlights: • Reflects the current thinking in chemical process R&D for small molecules • Retains similar structure and orientation to the first edition. • Contains approx. 85% new material • Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up) • Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes) • Replaces the first edition, although the first edition contains useful older examples that readers may refer toProvides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules"Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and morePresents guidelines for implementing and troubleshooting processes
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Unlike humans, who gather information largely through sight and sound, most living creatures rely heavily on chemical compounds from other organisms for their basic knowledge of the world. Among the various types of these compounds are the chemical signals exchanged between members of the same species that govern social interactions crucial to survival. These signals are called pheromones (from the Greek "pherein"--to carry--and "hormon"--exciting) and they are used to send warnings, establish territorial boundaries, provoke aggression, control sexual behavior, and locate food. In this volume, organic chemist William C. Agosta explores the chemistry of pheromones and the mechanisms by which they orchestrate animal behavior. Professor Agosta details the intricate process of identifying pheromones and determining the active components within these sometimes highly complex mixtures. He also demonstrates the value of this growing body of knowledge to our understanding of evolution, ecology, human behavior, and agricultural production. The result is a fascinating look at a research area that brings together investigators, information, technologies, and procedures from the fields of biology, chemistry, and behavioral science.
Chemical Communication spans the entire spectrum of life, from simple organisms, such as water molds and brown algae, to insects, birds, fish, reptiles, mammals, and in a provocative final chapter, human beings. Along the way, Dr. Agosta provides dozens of captivating examples of pheromones in action: certain male red-sided garter snakes, which increase their chances of mating successfully by "impersonating" a female, thus distracting rivals; or the bolas spiders, which capture male moths by hitting them with an adhesive ball on a string after emitting a female moth pheromone that lures the males within range. The book also includes important evidence that pheromones alter physiology as well as behavior. For example, young female mice reach maturity at an accelerated pace after constant exposure to adult male mice.
With topics such as stereochemistry, carboxylic acids, and unsaturated hydrocarbons, it's no wonder so many students have a bad reaction to organic chemistry class. Fortunately, this guide gives college students who are required to take organic chemistry an accessible, easy-to-follow companion to their textbooks.
* With the tremendous growth in the health-care job market, many students are pursuing college degrees that require organic chemistry
* Ian Guch is an award-winning chemistry teacher who has taught at both the high school and college levels
Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
This book is particularly designed for scientists and engineers working in various industries, including food, consumer products, pharmaceuticals, medicine, agriculture, nutraceuticals, dietary supplements, cosmetics, flavors, and fragrances. It offers a broad perspective on a variety of applications and processes, providing research information, figures, tables, illustrations, and references.
The book also lays the groundwork for further advancements in encapsulation technology and controlled release applications. Catering to professionals, researchers, students, and general readers in academia, industry, and research institutions, the Handbook of Encapsulation and Controlled Release is a much-needed reference on the state of the field and an authoritative resource for continued research and development in encapsulation and controlled release technologies.
Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature—and it’s rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements.
Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future.Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO—especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regionsFocuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agenciesIncludes many diagrams that clarify the design approach
Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design.
Each chapter of this book describes the important features of the methods evaluated, such as gas chromatography, wet absorption, spectrophotometry, diffusion, extraction, flame photometry, and dead-stop titration. These methods are classified into dynamic, multielement, and automatic determination methods. The advantages and limitations, as well as the speed, accuracy, reliability and economic aspects of these methods are examined. Considerable chapters are devoted to the analysis of various elements, including carbon, hydrogen, nitrogen, oxygen, sulfur, chlorine, bromine, iodine, fluorine, and phosphorus.
Organic and analytical chemists, as well as chemistry teachers and students will find this work invaluable.
In this gripping exploration, Nancy Langston shows how these chemicals have penetrated into every aspect of our bodies and ecosystems, yet the U.S. government has largely failed to regulate them and has skillfully manipulated scientific uncertainty to delay regulation. Personally affected by endocrine disruptors, Langston argues that the FDA needs to institute proper regulation of these commonly produced synthetic chemicals.
Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
• Helps students understand the skills andbasics they need to move from introductory to graduate organicchemistry classes
• Balances synthetic and physical organicchemistry in a way accessible to students
• Features extensive end-of-chapterproblems
• Updates include new examples anddiscussion of online resources now common for literaturesearches
• Adds sections on protecting groups andgreen chemistry along with a rewritten chapter surveying organicspectroscopy
Students wanting a comprehensive and accessible overview of organic chemistry to build the necessary foundations for a more detailed study will find this book an ideal source of the information they require. In addition, the structured presentation, highly graphical nature of the text and practice problems with outline answers will provide an invaluable framework and aid to revision for students preparing for examinations. Keynotes in Organic Chemistry is also a handy desk reference for advanced students, postgraduates and researchers.
For this second edition the text has been completely revised and updated. Colour has been introduced to clarify aspects of reaction mechanisms, and new margin notes to emphasise the links between different topics. The number of problems have been doubled to approximately 100, and includes spectra interpretation problems. Each chapter now starts with diagrams to illustrate the key points, and ends with a list of key reactions and a worked example.
With its acclaimed decision-based approach, Electron Flow inOrganic Chemistry enables readers to develop the essentialcritical thinking skills needed to analyze and solve problems inorganic chemistry, from the simple to complex. The author breaksdown common mechanistic organic processes into their basic units toexplain the core electron flow pathways that underlie theseprocesses. Moreover, the text stresses the use of analytical toolssuch as flow charts, correlation matrices, and energy surfaces toenable readers new to organic chemistry to grasp the fundamentalsat a much deeper level.
This Second Edition of Electron Flow in OrganicChemistry has been thoroughly revised, reorganized, andstreamlined in response to feedback from both students andinstructors. Readers will find more flowcharts, correlationmatrices, and algorithms that illustrate key decision-makingprocesses step by step. There are new examples from the field ofbiochemistry, making the text more relevant to a broader range ofreaders in chemistry, biology, and medicine. This edition alsooffers three new chapters:Proton transfer and the principles of stabilityImportant reaction archetypesQualitative molecular orbital theory and pericyclicreactions
The text's appendix features a variety of helpful tools,including a general bibliography, quick-reference charts andtables, pathway summaries, and a major decisions guide.
With its emphasis on logical processes rather than memorizationto solve mechanistic problems, this text gives readers a solidfoundation to approach and solve any problem in organicchemistry.
* The first reference work on named reactions to present colored schemes for easier understanding
* 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples
* An opening list of abbreviations includes both structures and chemical names
* Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works
* Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools
* Extensive index quickly locates information using words found in text and drawings
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Now in its updated and expanded Third Edition, Aquatic Chemistryremains the classic resource on the essential concepts of naturalwater chemistry. Designed for both self-study and classroom use,this book builds a solid foundation in the general principles ofnatural water chemistry and then proceeds to a thorough treatmentof more advanced topics. Key principles are illustrated with a widerange of quantitative models, examples, and problem-solvingmethods.
Major subjects covered include:
* Chemical Thermodynamics
* Solid-Solution Interface and Kinetics
* Trace Metals
* Acids and Bases
* Kinetics of Redox Processes
* Dissolved Carbon Dioxide
* Photochemical Processes
* Atmosphere-Water Interactions
* Kinetics at the Solid-Water
* Metal Ions in Aqueous Solution Interface
* Precipitation and Dissolution
* Particle-Particle Interaction
* Oxidation and Reduction
* Regulation of the Chemical
* Equilibria and Microbial Mediation Composition of Natural Waters
Castable Polyurethane Elastomers explains the production process of polyurethane components from both the theoretical and practical point of view. It describes the underlying concepts for the raw material supplier recommendations and explains how to achieve application-specific properties in polyurethane. The book explains the production of prepolymers with special focus on health and safety issues. It presents the different types of methods available on both the micro and macro levels and explains the rationale behind choosing the system needed to create a cost-effective, application-specific product.
Offering an inside look at the logic behind the formation of polyurethane components, Castable Polyurethane Elastomers enables materials scientists, engineers, and chemists to understand the total production process and reproduce the procedures to achieve desired results.
This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage.
This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.Updates to all chapters, including new examples and referencesChapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the bookChapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistryChapter 3 (Receptors): Drug-receptor interactions, cation-π and halogen bonding; atropisomers; case history of the insomnia drug suvorexantChapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesisChapter 5 (Enzyme Inhibition and Inactivation): New case histories: for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinibfor transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazidfor slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptinChapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examplesChapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolitesChapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates
"This splendid, at times humorous, and reasonably priced littlebook has much to commend it to undergraduate chemists and to otherscience students." —J. G. Farmer, University of Edinburgh
"Complex environmental issues are presented in simple terms tohelp readers grasp the basics and solve relevant problems."—J. Albaiges, University of Barcelona
"The main strength of the book lies in its explanations of thecalculation of quantitative relationships. Each chapter includes15-20 problems that are carefully chosen from a didacticstandpoint, for which the reader can find solutions at the end."—D. Lenoir, Institute for Ecological Chemistry
"What drew me to the first edition was the style – the nononsense, down-to-earth explanations and the practical examplesthat litter the text. The dry humor expressed in the footnotes isgreat and reminds me of other classic texts." —T. Clough,Lincoln University
A practical approach to environmental chemistry
Providing readers with the fundamentals of environmentalchemistry and a toolbox for putting them into practice, Elements ofEnvironmental Chemistry, Second Edition is a concise, accessible,and hands-on volume designed for students and professionals workingin the chemical and environmental sciences.
Tutorial in style, this book fully incorporates real-worldproblems and extensive end-of-chapter problem sets to immerse thereader in the field. Chapters cover mass balance, chemicalkinetics, carbon dioxide equilibria, pesticide structures and muchmore. Extensively revised, updated, and expanded, this SecondEdition includes new chapters on atmospheric chemistry, climatechange, and polychlorinated biphenyls and dioxins, and brominatedflame retardants. In addition, new practice problems and a helpfultutorial on organic chemistry names and structures have been addedto improve both the scope and accessibility of the book.