“Artfully envisions a breathtakingly better world.” —Los Angeles Times
“Elaborate, smart and persuasive.” —The Boston Globe
“A pleasure to read.” —The Wall Street Journal
One of CBS News’s Best Fall Books of 2005 • Among St Louis Post-Dispatch’s Best Nonfiction Books of 2005 • One of Amazon.com’s Best Science Books of 2005
A radical and optimistic view of the future course of human development from the bestselling author of How to Create a Mind and The Age of Spiritual Machines who Bill Gates calls “the best person I know at predicting the future of artificial intelligence”
For over three decades, Ray Kurzweil has been one of the most respected and provocative advocates of the role of technology in our future. In his classic The Age of Spiritual Machines, he argued that computers would soon rival the full range of human intelligence at its best. Now he examines the next step in this inexorable evolutionary process: the union of human and machine, in which the knowledge and skills embedded in our brains will be combined with the vastly greater capacity, speed, and knowledge-sharing ability of our creations.
From the Trade Paperback edition.
A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging.
Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach.
In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
From the Trade Paperback edition.
In this magisterial look at some twenty-five years of scientific and social development, Sheila Jasanoff compares the politics and policy of the life sciences in Britain, Germany, the United States, and in the European Union as a whole. She shows how public and private actors in each setting evaluated new manifestations of biotechnology and tried to reassure themselves about their safety.
Three main themes emerge. First, core concepts of democratic theory, such as citizenship, deliberation, and accountability, cannot be understood satisfactorily without taking on board the politics of science and technology. Second, in all three countries, policies for the life sciences have been incorporated into "nation-building" projects that seek to reimagine what the nation stands for. Third, political culture influences democratic politics, and it works through the institutionalized ways in which citizens understand and evaluate public knowledge. These three aspects of contemporary politics, Jasanoff argues, help account not only for policy divergences but also for the perceived legitimacy of state actions.
--Hans Camenzind, inventor of the 555 timer (the world's most successful integrated circuit), and author of Much Ado About Almost Nothing: Man's Encounter with the Electron (Booklocker.com)
"A fabulous book: well written, well paced, fun, and informative. I also love the sense of humor. It's very good at disarming the fear. And it's gorgeous. I'll be recommending this book highly."
--Tom Igoe, author of Physical Computing and Making Things Talk
Want to learn the fundamentals of electronics in a fun, hands-on way? With Make: Electronics, you'll start working on real projects as soon as you crack open the book. Explore all of the key components and essential principles through a series of fascinating experiments. You'll build the circuits first, then learn the theory behind them!
Build working devices, from simple to complex You'll start with the basics and then move on to more complicated projects. Go from switching circuits to integrated circuits, and from simple alarms to programmable microcontrollers. Step-by-step instructions and more than 500 full-color photographs and illustrations will help you use -- and understand -- electronics concepts and techniques.Discover by breaking things: experiment with components and learn from failure Set up a tricked-out project space: make a work area at home, equipped with the tools and parts you'll need Learn about key electronic components and their functions within a circuit Create an intrusion alarm, holiday lights, wearable electronic jewelry, audio processors, a reflex tester, and a combination lock Build an autonomous robot cart that can sense its environment and avoid obstacles Get clear, easy-to-understand explanations of what you're doing and why
This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike.
New to this edition:
*Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves
*Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems
In Regenesis, Harvard biologist George Church and science writer Ed Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Vitamin D deficiency is the most common medical condition in the world. In America alone, over 200 million people lack sufficient levels of vitamin D and may consequently suffer from chronic health conditions, ranging from daily annoyances like fatigue and pain to life-threatening illnesses such as diabetes, heart disease, and cancer. But few people know why vitamin D is so important and what they can do to avoid the myriad ailments associated with deficiency, including heart disease, cancer, and osteoporosis.
There is no better person to demystify this vitamin and showcase its place in human health than author Michael F. Holick, M.D., Ph.D.-the father of modern vitamin D research. With more than three decades spent studying the relationship between vitamin D, limited sun exposure, and human well-being, Dr. Holick shares his findings on how combining the natural curative properties of the sun along with small lifestyle changes can help everyone to live a substantially healthier life.
Armed with a three-step plan incorporating safe amounts of sun exposure, the right supplementation, and eating foods rich in vitamin D, Dr. Holick provides prescriptive advice for anyone- from relatively healthy people to those suffering from chronic or even fatal diseases- on how to easily rebuild and maintain optimal levels of this essential hormone.
Rich with anecdotes and entertaining case studies, The Vitamin D Solution also presents research from around the world to serve as a wake-up call on this potentially lifesaving hormone for health.
This may come as a surprise to you: eczema is one of the most treatable skin conditions known to man.
A big percentage of eczema sufferers feel that their skin condition will be bothering them forever - this is simply not true. When you know how to identify the triggers of eczema and how to remove these common triggers, the eczema actually heals on its own.
Here Are Three Good Reasons To Why You Can Start Curing Your Eczema Naturally Today
ONE: Eczema can be caused by both internal and external factors - examples of external factors include the use of detergents and even the weather.
TWO: Simple lifestyle changes can actually resolve your eczema.
THREE: Key changes in your diet can have an immense, beneficial effect on your eczema.
Here is something dermatologists don't want you to know: naturally remedying eczema is extremely simple. You just need to know what to do, and how to do it! Even if you're a total beginner and haven't got a clue where to start, you can start treating your eczema at home within the day!
There are essentially 3 main things you need to know about naturally curing eczema:
1. How to identify the actual symptoms of eczema and how to differentiate eczema from more serious skin conditions
2. How to identify the key triggers of eczema
3. How to remove the key triggers so that your eczema will resolve on its own
"Eczema No More" covers all of this, and a lot more. And when you read it, you'll be BLOWN AWAY with how simple it really is to naturally treat your eczema.
Here's just a taste of what you'll discover...
- How to identify the symptoms of eczema with these 3 simple techniques...
- 3 little known, yet simple ways to distinguish eczema from other skin conditions...
- 6 time tested and proven strategies for clearer and healthier skin - free from itching and soreness...
- Secret of expert skin care that few people ever know about...
- 3 proven steps to improve your skin care regimen at home...
- How to create the perfect environment for your skin during bathtime...
- 2 simple keys (that are right in front of your eyes) to avoid triggering an eczema outbreak...
- WARNING: 3 things you should never do when it comes to your own diet...
- How to cure eczema in children...
- You'll discover in just a few short minutes how to modify your daily diet for overall better skin...
- 7 everyday but often overlooked tips and tricks for improving your lifestlye so it won't exacerbate your eczema...
- And much more...
Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners.
It provides a ‘how-to’ for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements.
An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making.Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebarsCase studies are interspersed throughout each chapter to support key concepts and best practices.Enhanced by use of numerous detailed graphics, tables and flow charts
Following on from the Industrial or machine age, the space age and the digital age, the Augmented Age will be based on four key disruptive themes—Artificial Intelligence, Experience Design, Smart Infrastructure, and HealthTech. Historically the previous ‘ages’ bought significant disruption and changes, but on a net basis jobs were created, wealth was enhanced, and the health and security of society improved. What will the Augmented Age bring? Will robots take our jobs, and AI’s subsume us as inferior intelligences, or will this usher in a new age of abundance?
Augmented is a book on future history, but more than that, it is a story about how you will live your life in a world that will change more in the next 20 years than it has in the last 250 years. Are you ready to adapt? Because if history proves anything, you don't have much of a choice.
Eve Herold's Beyond Human examines the medical technologies taking shape at the nexus of computing, microelectronics, engineering, nanotechnology, cellular and gene therapies, and robotics. These technologies will dramatically transform our lives and allow us to live for hundreds of years. Yet, with these blessings come complicated practical and ethical issues, some of which we can predict, but many we cannot.
Beyond Human taps the minds of doctors, scientists, and engineers engaged in developing a host of new technologies while telling the stories of some of the patients courageously testing the radical new treatments about to come into the market.
Beyond Human asks the difficult questions of the scientists and bioethicists who seek to ensure that as our bodies and brains become ever more artificial, we hold onto our humanity. In this new world, will everyone have access to technological miracles, or will we end up living in a world of radical disparities? How will society accommodate life spans that extend into hundreds of years? Will we and our descendants be able to bring about the dream of a future liberated by technology, or will we end up merely serving the machines and devices that keep us healthy, smart, young, and alive?
R. Ford Denison shows how both biotechnology and traditional plant breeding can use Darwinian insights to identify promising routes for crop genetic improvement and avoid costly dead ends. Denison explains why plant traits that have been genetically optimized by individual selection--such as photosynthesis and drought tolerance--are bad candidates for genetic improvement. Traits like plant height and leaf angle, which determine the collective performance of plant communities, offer more room for improvement. Agriculturalists can also benefit from more sophisticated comparisons among natural communities and from the study of wild species in the landscapes where they evolved.
Darwinian Agriculture reveals why it is sometimes better to slow or even reverse evolutionary trends when they are inconsistent with our present goals, and how we can glean new ideas from natural selection's marvelous innovations in wild species.
Laser Dermatology: Pearls and Problems is different from other laser dermatology books. Each of the five chapters begins by highlighting key points and essential concepts, then focuses on the pearls and problems for each area – based on the author’s vast experience in the field of laser dermatology. Dr. Goldberg addresses:Vascular Lasers Laser Hair Removal Pigmented Lesions, Tattoos, and Disorders of Hypopigmentation Ablative Lasers and Devices Non-Ablative Photorejuvenation and Skin Remodeling
Dr. Goldberg goes beyond the standard “before and after” approach to use actual images to demonstrate the pearls and pitfalls discussed in the text.
Genetically modified organisms (GMOs) including plants and the foods made from them, are a hot topic of debate today, but soon related technology could go much further and literally change what it means to be human. Scientists are on the verge of being able to create people who are GMOs.
Should they do it? Could we become a healthier and ''better'' species or might eugenics go viral leading to a real, new world of genetic dystopia? GMO Sapiens tackles such questions by taking a fresh look at the cutting-edge biotech discoveries that have made genetically modified people possible.
Bioengineering, genomics, synthetic biology, and stem cells are changing sci-fi into reality before our eyes. This book will capture your imagination with its clear, approachable writing style. It will draw you into the fascinating discussion of the life-changing science of human genetic modification.Contents:An Introduction to Playing GodThe Birth and Explosive Growth of GMOsHuman CloningBuild-a-Baby Better via GeneticsDIY Guide to Creating GMO SapiensEugenics and TranshumanismCultural Views on Human Genetic ModificationGMO Sapiens Today and Tomorrow
Readership: Undergraduate biology majors, graduate biology majors, non-experts interested in GMOs, biologists and teenagers interested in cloning and human genetic modification.
Key Features:Books on this hot new topic of creating GMO people are rare, tend to be out-of-date, or have narrow topic rangesThe goal of this book is to educate and entertain an educated lay audience about human genetic modificationKeywords:GMO;Genetically Modified Organism;GMO Sapien;Cloning;Genomics;Designer Babies;Mitochondrial Transfer;Stem Cells;Infertility
"What I find troubling, exciting but scary, is that I find myself agreeing with an undertone, I do not support human germline genetic modification but with all the new information and perspectives available to me I have found myself questioning my own views and will be watching any developments with a fascinated interest I would rather not admit to."The NODE
This book provides an understanding of the microbial challenges to the safety of low aw foods, and a historic backdrop to the paradigm shift now highlighting low aw foods as vehicles for foodborne pathogens. Up-to-date facts and figures of foodborne illness outbreaks and product recalls are included. Special attention is given to the uncanny ability of Salmonella to persist under dry conditions in food processing plants and foods. A section is dedicated specifically to processing plant investigations, providing practical approaches to determining sources of persistent bacterial strains in the industrial food processing environment. Readers are guided through dry cleaning, wet cleaning and alternatives to processing plant hygiene and sanitation. Separate chapters are devoted to low aw food commodities of interest including spices, dried dairy-based products, low aw meat products, dried ready-to-eat cereal products, powdered infant formula, nuts and nut pastes, flours and meals, chocolate and confectionary, dried teas and herbs, and pet foods. The book provides regulatory testing guidelines and recommendations as well as guidance through methodological and sampling challenges to testing spices and low aw foods for the presence of foodborne pathogens. Chapters also address decontamination processes for low aw foods, including heat, steam, irradiation, microwave, and alternative energy-based treatments.
Skim the Top 100 Secrets chapter and Key Points boxes for a fast overview of the secrets you must know for success on the boards and in practice.
Enjoy faster, easier review and master the top issues in dermatology with mnemonics, lists, quick-reference tables, and an informal tone that sets this review book apart from the rest.Hone your diagnostic skills with more than 500 superb full-color images throughout.
View photos in a new, expanded size for optimal visual reference.
Gain a clearer understanding of neurocutaneous melanocytosis with an entirely new section on this topic.
Access key information faster than ever with eight new tables and more than 90 new figures.
Stay current with thorough updates to both text and references in all chapters, and Web Resources added to the bibliography.
But what about the average person? How will the Singularity affect our daily lives—our jobs, our families, and our wealth?
Singularity Rising: Surviving and Thriving in a Smarter, Richer, and More Dangerous World focuses on the implications of a future society faced with an abundance of human and artificial intelligence. James D. Miller, an economics professor and popular speaker on the Singularity, reveals how natural selection has been increasing human intelligence over the past few thousand years and speculates on how intelligence enhancements will shape civilization over the next forty years.
Miller considers several possible scenarios in this coming singularity:
• A merger of man and machine making society fantastically wealthy and nearly immortal
• Competition with billions of cheap AIs drive human wages to almost nothing while making investors rich
• Businesses rethink investment decisions to take into account an expected future period of intense creative destruction
• Inequality drops worldwide as technologies mitigate the cognitive cost of living in impoverished environments
• Drugs designed to fight Alzheimer's disease and keep soldiers alert on battlefields have the fortunate side effect of increasing all of their users’ IQs, which, in turn, adds a percentage points to worldwide economic growth
Singularity Rising offers predictions about the economic implications for a future of widely expanding intelligence and practical career and investment advice on flourishing on the way to the Singularity.
The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression.
The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.
See how to perform a variety of key procedures demonstrating endovenous radiofrequency closure, CoolTouch endovenous ablation, cross polarization visualization, PPG digital measuring, sclerotherapy of the lateral venous system showing reflux, foam sclerotherapy, telangiectatic matting, ambulatory phlebectomy, and draining of intravascular coagulum.
Apply the best practices and global perspectives from a newly reorganized team of U.S.-based and international authors and contributors.
Access the complete contents from any computer at www.expertconsult.com, complete with the full text and entire image bank.
Eating in the Dark tells the story of how these new foods quietly entered America’s food supply. Kathleen Hart explores biotechnology’s real potential to enhance nutrition and cut farmers’ expenses. She also reveals the process by which American government agencies decided not to label genetically modified food, and not to require biotech companies to perform even basic safety tests on their products. Combining a balanced perspective with a sense of urgency, Eating in the Dark is a captivating and important story account of the science and politics propelling the genetic alteration of our food.
From the Trade Paperback edition.
The Clinical Engineering Handbook meets a long felt need for a comprehensive book on all aspects of clinical engineering that is a suitable reference in hospitals, classrooms, workshops, and governmental and non-governmental organization. The Handbook’s thirteen sections address the following areas: Clinical Engineering; Models of Clinical Engineering Practice; Technology Management; Safety Education and Training; Design, Manufacture, and Evaluation and Control of Medical Devices; Utilization and Service of Medical Devices; Information Technology; and Professionalism and Ethics. The Clinical Engineering Handbook provides the reader with prospects for the future of clinical engineering as well as guidelines and standards for best practice around the world. From telemedicine and IT issues, to sanitation and disaster planning, it brings together all the important aspects of clinical engineering.Clinical Engineers are the safety and quality faciltators in all medical facilitiesThe most definitive, comprehensive, and up-to-date book available on the subject of clinical engineeringOver 170 contributions by leaders in the field of clinical engineering
Filling the void, Biotechnology Operations: Principles and Practices reflects this integrative philosophy, serving as a practical guide for students, professionals, or anyone else with interests in the biotech industry. Although many books emphasize specific technical aspects of biotech, this is perhaps the first to integrate essential concepts of product development and scientific and management skills with the seven functional areas of biotechnology:
Biomanufacturing Clinical trials Nonclinical studies Project management Quality assurance Quality control Regulatory affairs
A practical roadmap to optimizing biotechnology operations, this reference illustrates how to use specific product planning, design, and project management processes to seamlessly merge plans and efforts in the key functional areas. Applying lessons learned throughout the nascent history of biotech, author Michael Roy highlights developmental principles that could bring future products to market more safely and efficiently. Drawing from his experiences working in industry and teaching a graduate course at the University of Wisconsin, this hotly anticipated book clarifies basic methodologies and practices to help reduce risks and resolve problems as future technological discoveries are developed into tangible products.
Winner of a CHOICE Outstanding Academic Book Award 2011
"... takes the revolutionary concepts and techniques that have traditionally been fodder for graduate study and makes them accessible for all. ... outstanding introduction to the broad field of nanotechnology provides a solid foundation for further study. ... Highly recommended."
—N.M. Fahrenkopf, University at Albany, CHOICE Magazine 2011
Give your students the thorough grounding they need in nanotechnology. A rigorous yet accessible treatment of one of the world’s fastest growing fields, Nanotechnology: Understanding Small Systems, Third Edition provides an accessible introduction without sacrificing rigorous scientific details. This approach makes the subject matter accessible to students from a variety of disciplines. Building on the foundation set by the first two bestselling editions, this third edition maintains the features that made previous editions popular with students and professors alike.
See What’s New in the Third Edition:
Updated coverage of the eight main facets of nanotechnology Expanded treatment of health/environmental ramifications of nanomaterials Comparison of macroscale systems to those at the nanoscale, showing how scale phenomena affects behavior New chapter on nanomedicine New problems, examples, and an exhaustive nanotech glossary
Filled with real-world examples and original illustrations, the presentation makes the material fun and engaging. The systems-based approach gives students the tools to create systems with unique functions and characteristics. Fitting neatly between popular science books and high-level treatises, the book works from the ground up to provide a gateway into an exciting and rapidly evolving area of science.
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Internationally best-selling poet Christian Bök has spent more than ten years writing what promises to be the first example of "living poetry." After successfully demonstrating his concept in a colony of E. coli, Bök is on the verge of enciphering a beautiful, anomalous poem into the genome of an unkillable bacterium (Deinococcus radiodurans), which can, in turn, "read" his text, responding to it by manufacturing a viable, benign protein, whose sequence of amino acids enciphers yet another poem. The engineered organism might conceivably serve as a post-apocalyptic archive, capable of outlasting our civilization.
Book I of The Xenotext constitutes a kind of "demonic grimoire," providing a scientific framework for the project with a series of poems, texts, and illustrations. A Virgilian welcome to the Inferno, Book I is the "orphic" volume in a diptych, addressing the pastoral heritage of poets, who have sought to supplant nature in both beauty and terror. The book sets the conceptual groundwork for the second volume, which will document the experiment itself. The Xenotext is experimental poetry in the truest sense of the term.
Christian Bök is the author of Crystallography (1994) and Eunoia (2001), which won the Griffin Poetry Prize. He teaches at the University of Calgary in Alberta, Canada.
Avoiding the hype of popular science and the pessimism of most social science, Nikolas Rose analyzes contemporary molecular biopolitics, examining developments in genomics, neuroscience, pharmacology, and psychopharmacology and the ways they have affected racial politics, crime control, and psychiatry. Rose analyzes the transformation of biomedicine from the practice of healing to the government of life; the new emphasis on treating disease susceptibilities rather than disease; the shift in our understanding of the patient; the emergence of new forms of medical activism; the rise of biocapital; and the mutations in biopower. He concludes that these developments have profound consequences for who we think we are, and who we want to be.
Generations of clinicians, skin biologists, residents, and educators have acclaimed Fitzpatrick’s as the most authoritative and complete guide to dermatologic basic sciences, histopathology, diagnosis, and treatment. Edition after edition, it reflects the latest insights into skin diseases and skin biology—and their practical relevance to general internal medicine—while covering the scientific foundations of the specialty.
This classic yet cutting-edge text is supported by the expert insights of more than 500 internationally respected contributors, and it covers everything dermatologists need to know about skin, dermatologic signs of underlying disease, and the management of all skin diseases, including acne, skin cancer, and psoriasis.
FEATURESMore than 3000 full-color photographs DVD with image bank includes downloadable figures from the text New illustration style makes difficult concepts easier to understand Therapeutic ladders with first, second, and third line therapies New or thoroughly revised chapters on Psoriasis; Skin disease in immunosuppressed patients; Epidermal stem cells; Hair growth disorders; Neonatal, pediatric, and adolescent dermatology; Radiotherapy; Immunobiologicals and cytokines; Lasers for rejuvenation Expanded medical and surgical therapeutics sections guide you through all treatment options
Microorganisms in Foods 5, 7, and the second edition of Microorganisms in Foods 6 are for anyone using microbiological testing and/or engaged in setting Microbiological Criteria, whether for the purpose of Governmental Food Inspection and Control or in Industry, and for those identifying the most effective use of microbiological testing in the food chain. The contents are essential reading for food processors, food microbiologists, food technologists, veterinarians, public health workers and regulatory officials. For students in Food Science and Technology they offer a wealth of information on Food Microbiology and Food Safety Management, with many references for further study.
The information has been prepared by the International Commission on Microbiological Specifications for Foods (ICMSF). The ICMSF was formed in response to the need for internationally acceptable and authoritative decisions on microbiological limits for foods moving in international commerce. Currently the membership consists of eighteen food microbiologists from eleven countries, drawn from governmental laboratories in public health, agriculture, and food technology, from universities and from the food industry.
Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors.A comprehensive overview of switchable and responsive materials and surfacesIncludes in depth analysis of thermo-responsive polymers, photonic sensitive materials and peptide-based surfacesDetailed exploration of biological interactions of responsive and switchable surfaces, covering stimuli-sensitive polymers for drug delivery, surfaces with proteins/cells and application of polymers in medical devices
This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike.Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valvesOffers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systemsFull-color presentation throughout
Advances in the fundamental knowledge surrounding biotechnology, novel materials, and advanced engineering approaches continue to be translated into bioprocesses that bring new products to market at a significantly faster pace than most other industries. Industrial scale biotechnology and new manufacturing methods are revolutionizing medicine, environmental monitoring and remediation, consumer products, food production, agriculture, and forestry, and continue to be a major area of research.
The downstream stage in industrial biotechnology refers to recovery, isolation, and purification of the microbial products from cell debris, processing medium and contaminating biomolecules from the upstream process into a finished product such as biopharmaceuticals and vaccines.
Downstream process design has the greatest impact on overall biomanufacturing cost because not only does the biochemistry of different products ( e.g., peptides, proteins, hormones, antibiotics, and complex antigens) dictate different methods for the isolation and purification of these products, but contaminating byproducts can also reduce overall process yield, and may have serious consequences on clinical safety and efficacy. Therefore downstream separation scientists and engineers are continually seeking to eliminate, or combine, unit operations to minimize the number of process steps in order to maximize product recovery at a specified concentration and purity.
Based on Wiley's Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, this volume features fifty articles that provide information on down- stream recovery of cells and protein capture; process development and facility design; equipment; PAT in downstream processes; downstream cGMP operations; and regulatory compliance.
It covers:Cell wall disruption and lysis Cell recovery by centrifugation and filtration Large-scale protein chromatography Scale down of biopharmaceutical purification operations Lipopolysaccharide removal Porous media in biotechnology Equipment used in industrial protein purification Affinity chromatography Antibody purification, monoclonal and polyclonal Protein aggregation, precipitation and crystallization Freeze-drying of biopharmaceuticals Biopharmaceutical facility design and validation Pharmaceutical bioburden testing Regulatory requirements
Ideal for graduate and advanced undergraduate courses on biomanufacturing, biochemical engineering, biophar- maceutical facility design, biochemistry, industrial microbiology, gene expression technology, and cell culture technology, Downstream Industrial Biotechnology is also a highly recommended resource for industry professionals and libraries.
New to this Edition:Updated and increased coverage of real time PCR and the mathematics used to measure gene expressionMore sample problems in every chapter for readers to practice concepts
Cosmetic Dermatology offers complete coverage of the latest, most effective skin care agents and procedures. Spanning the entire spectrum of cosmetic dermatology, it takes you through the most current medications, cosmeceuticals, and procedures. Presented in full color, the book is firmly grounded in an evidence-based, clinically-relevant approach--making it perfect for use in everyday practice.
FEATURES:Guidance on the efficacy of over-the-counter and prescription skin care products Step-by-step review of must-know procedures A focus on the newest drugs and topical agents NEW! Expanded insights into laser treatments, varicose veins, and cosmeceuticals NEW! More full-color clinical images in every chapter... 450 in all! NEW! Significant revisions in every chapter to help you keep pace with the many fast-breaking developments in the specialty
- Inflammatory conditions (including contact dermatitis, alopecia, erythema multiforme, pemphigus, bullous pemphigoid, porphyria, pruritus, psoriasis, rosacea, seborrhea, urticaria, xerosis, and more)
- Infections (fungus, herpes simplex and zoster, scabies, lice, and warts)
- Skin signs in systemic disease (skin tags, cutaneous metastases, xanthomas)
- Regional dermatoses (intertrigo, leg ulcers, pressure sores)
- Benign tumors (chondrodermatitis, cysts, ganglion, fibrous papule, seborrheic keratoses, lentigines, and benign vascular lesions)
- Pre-malignant and malignant tumors (actinic keratoses, angiosarcoma, basal cell carcinoma, dermatofibroma and dermatofibrosarcoma protuberans, intraepidermal neoplasia, Kaposi's sarcoma, keratoacanthoma, lentigo maligna, cutaneous lymphoma, Mycosis fiungoides, melanoma, nevi and moles, and squamous cell carcinoma)
This book provides a detailed overview of the encapsulation technologies available for use in food products, food processing, and food production. The book aims to inform those who work in academia or R&D about both the delivery of food compounds via encapsulation and food processing using immobilized cells or enzymes. The structure of the book is according to the use of encapsulates for a specific application. Emphasis is placed on strategy, since encapsulation technologies may change. Most chapters include application possibilities of the encapsulation technologies in specific food products or processes.
The first part of the book reviews general technologies, food-grade materials, and characterization methods for encapsulates.
The second part discusses encapsulates of active ingredients (e.g., aroma, fish oil, minerals, vitamins, peptides, proteins, probiotics) for specific food applications.
The last part describes immobilization technologies of cells and enzymes for use within food fermentation processes (e.g., beer, wine, dairy, meat), and food production (e.g., sugar conversion, production of organic acids or amino acids, hydrolysis of triglycerides).
Edited by two leading experts in the field, Encapsulation Technologies for Food Active Ingredients and Food Processing will be a valuable reference source for those working in the academia or food industry. The editors work in both industry or academia, and they have brought together in this book contributions from both fields.