Blood carries life, yet the sight of it makes people faint. It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquitousness, the few tablespoons of blood discharged by 800 million women are still regarded as taboo: menstruation is perhaps the single most demonized biological event.
Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to the breakthough of the "liquid biopsy," which promises to diagnose cancer and other diseases with a simple blood test. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the US is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.
Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.
With the dawn of science, blood came to be seen as a component of human anatomy, capable of being isolated, studied, used. Starr describes the first documented transfusion: In the seventeenth century, one of Louis XIV's court physicians transfers the blood of a calf into a madman to "cure" him. At the turn of the twentieth century a young researcher in Vienna identifies the basic blood groups, taking the first step toward successful transfusion. Then a New York doctor finds a way to stop blood from clotting, thereby making all transfusion possible.
In the 1930s, a Russian physician, in grisly improvisation, successfully uses cadaver blood to help living patients--and realizes that blood can be stored. The first blood bank is soon operating in Chicago.
During World War II, researchers, driven by battlefield needs, break down blood into usable components that are more easily stored and transported. This "fractionation" process--accomplished by a Harvard team--produces a host of pharmaceuticals, setting the stage for the global marketplace to come. Plasma, precisely because it can be made into long-lasting drugs, is shipped and traded for profit; today it is a $5 billion business.
The author recounts the tragic spread of AIDS through the distribution of contaminated blood products, and describes why and how related scandals have erupted around the world. Finally, he looks at the latest attempts to make artificial blood.
Douglas Starr has written a groundbreaking book that tackles a subject of universal and urgent importance and explores the perils and promises that lie ahead.
The definitive haematology textbook of choice for medical students
Hoffbrand's Essential Haematology has built a reputation as the flagship haematology textbook for both students and junior doctors, providing an authoritative introduction to the subject.
Now in its 7th edition, this classic text provides up-to-date knowledge of the pathogenesis, clinical and laboratory features, treatment of blood and bone marrow disorders, in its concise and user-friendly style.
Hoffbrand's Essential Haematology outlines the basic principles of clinical and laboratory haematology and shows how manifestations of blood diseases can be explained by new knowledge of the disease processes. It is an indispensable resource for students and trainees and an essential read for all specialists who are interested in updating their knowledge.
Hoffbrand’s Essential Haematology:Provides up-to-date knowledge of the pathogenesis, clinical and laboratory features and treatment of all blood disorders Features detailed information on the new genetics of leukaemia and lymphoma Includes a new chapter on thrombosis, focussing on the new oral anticoagulants Is beautifully presented, with over 300 colour illustrations Comprehensively covers both theory and treatment regimes
Includes a companion website at www.wileyessential.com/haematology featuring all the figures and tables from the book, and over 300 interactive multiple choice questions.
This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.
A Doody's Core Title for 2017!
LANGE Pathophysiology of Blood Disorders, Second Edition is a well-illustrated, easy-to-absorb introduction to the physiological principles underlying the regulation and function of blood cells and hemostasis, as well as the pathophysiologic mechanisms responsible for the development of blood disorders. Featuring a strong emphasis on key principles, the book also covers diagnosis and management primarily within a framework of pathogenesis.
The organization and content of this book are based on a 3-week hematology course given to students in their second year at Harvard Medical School. All of the authors are lecturers in this course and many of the figures have been taken directly or adapted from their lectures.
FEATURES OF THE SECOND EDITION:
• NEW summary boxes with high yield points to remember
• All figures have been redrawn by a single artist for quality and consistency
• A more user-friendly presentation
• Each chapter includes learning objectives, and self-assessment questions with detailed explanations
• Numerous tables and diagrams encapsulate important information
Hailed for its uniformity of style, clarity, brevity, and high level of scientific rigor and clinical relevance, LANGE Pathophysiology of Blood Disorders, Second Edition will prove valuable to medical students, as well as physicians at all stages of their training.
For hematology and oncology fellows as well as practicing clinicians needing a refresher before taking MOC, this handy study guide provides succinct overviews of all blood disorders, syndromes and diseases with practice questions on the go. Each disorder or disease-based chapter provides the same structure for ease of use beginning with the epidemiology, and followed by the etiology and risk factors, signs and symptoms, diagnostic criteria, indications for treatment, prognostic factors, treatment recommendations, and special considerations. The authors provide the most accurate and up-to-date information, including well-established treatment regimens for a variety of blood disorders, including iron disorders, bone marrow failure syndromes, platelet and megakaryocytic disorders, hemostasis, thrombosis, and hematologic malignancies. Later chapters review other major subspecialty areas found on the exam including transfusion medicine and hematopoietic cell transplantation. With 200 board-style questions and answers with detailed rationales, Hematology Board Review is the go-to, quick review for any trainee preparing for initial certification and for hematologists or oncologists preparing for recertification.
Key Features:Includes 200 board-style questions and answers with rationalesProvides key point summaries of each topic area for quick study and easy recallThorough coverage of hematologic malignancies, blood disorders, transfusion medicine, hematopoietic cell transplantation, and standard treatment regimensTables providing key data and information related to staging, treatment options, and disease classifications
Designed for medical students, residents, and fellows, this user-friendly portable reference is also the perfect companion on the ward for pediatric hematology and oncology nurses.
The fourth edition contains new chapters that reflect the most recent developments whilst other chapters have been extensively revised to include the new tests and treatments that are now available for certain conditions such as chronic leukaemia, multiple myeloma and bleeding disorders.
With contributions from leading experts in their respective fields, this text provides an ideal reference for primary care practitioners and other healthcare professionals working with patients who have blood related problems.
New to the Third Edition:a thorough examination of all the agents involved in treating thrombosis chapters on biomarkers, testing, and pharmacogenomics key topics, including new targets for antithrombotics, the development of novel classes of platelet inhibitors, new thrombolytic therapies, and evolving clinical uses of thrombolytics for ischemic stroke and venous thrombosis the hemostatic and thrombotic pathways
The new edition has details of the theory and practice of traditional drugs and the use of non-Vitamin K antagonist oral anticoagulants (NOACs) and overall the book will enable the practitioner to manage their patients with confidence
What is deep vein thrombosis and pulmonary embolism and why are they important?
Who is at risk of these conditions and why?
Recognising and confirming DVT and PE
What have we got to treat these conditions?
Clinical practice of anticoagulation
Heparin and LMWH
Non-vitamin K antagonist anticoagulants (NOACs)
What happens if something goes wrong? – Haemorrhage
Answers to Consolidation notes and Case Studies
Supplies the practicing and trainee hematologist with a practical and immediately applicable compendium of answers to clinical questions Covers the spectrum of the hematopoietic cell transplant specialty, in particular practical issues in transplant patient care, and the set up and functioning of a transplant program Contains concise chapters written with a focus on tables, algorithms and figures to aid rapid referral Benefits from expert contributions from an international authorship
Expertise. All editors and authors are scientists and oncologists specializing in cancer immunotherapy, and are involved in scientific discovery from the early stage of immune-checkpoint inhibitors to today’s daily patient care. Their insights, expertise and experience guarantee the high quality and authority in the science, medicine and practice of cancer immunotherapy.
Patient-friendly. This book is written for cancer patients in order to meet their needs when considering immunotherapy. As an educational tool, this book will help the reader balance the risks and benefits based on both science and clinical facts, and therefore to make the best choice in receiving or withdrawing from immunotherapy.
Disease Specificity. Cancer is a complicated disease involving multiple stages and pathology. Its response to immunotherapy is individualized and varies depending on cancer types. The authors’ expertise in treating different types of cancers, including melanoma, lung, kidney, bladder, and lymphoma, provides disease-specific insights in applying immunotherapy to each disease.
As a concise yet comprehensive summary of the current status of the field, Management of Castration Resistant Prostate Cancer serves as a very useful resource for physicians and researchers dealing with this challenging malignancy.
A Beginner's Guide to Blood Cells is an ideal for;
Trainee laboratory technicians and scientists
Students studying the physiology or pathology of the blood
Those preparing for haematology examinations
Why Buy This Book?
Unique pocket guide, written by Barbara Bain – a world-renowned expert in the field of blood morphology
Outlines the basics of diagnostic haematology
Includes an invaluable self-assessment section
NEW EDITION – now includes more information on clinical aspects and further tests
This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.
CancerScam investigates Project ASSIST, the joint undertaking between the American Cancer Society and the National Cancer Institute (NCI). CancerScam details the charities' collaborative efforts to divert millions of dollars in federal cancer funds--under the guise of improving the public health through reducing smoking--to build political coalitions. Bennett and DiLorenzo suggest that the antitobacco campaign is a smokescreen for raising taxes on tobacco and earmarking the increased revenues for the financial benefit of ACS and its allied charities. CancerScam reveals how concern about the AIDS lobby's success in obtaining scarce research funds motivated the NCI to build political coalitions at the grass-roots level which could lobby for federal funding of cancer research. Bennett and DiLorenzo believe that public support of the ACS will be undermined when its emphasis on politics becomes better known and its reputation erodes as it is perceived as little more than an extension of government, subject to bureaucratic regulation and loss of independence.
CancerScam is the follow-up to Bennett and DiLorenzo's Unhealthy Charities: Hazardous to Your Health and Wealth. It is a brave effort that brilliantly shows how government bureaucrats steal funds intended for the highest public purposes and use them for narrow political advancement. As such it will be of interest to those interested in public policy and political science, nonprofit executives, and policymakers.
The Coagulation Consult covers major topics of interest to hematologists who are asked to consult on individuals with coagulation related diseases, and encompasses the field’s most recent developments. This “case-directed” book describes state-of-the-art approaches to patients with bleeding and clotting disorders, as well as laboratory tests for coagulation. Chapters include different vignettes, focus on typical clinical consult questions, and lay out specific types of treatment. Practicing clinicians being confronted with coagulation consult students, residents, fellows and attending physicians will find this unique text an invaluable resource for some of the newer areas of coagulation science, therapy and pharmacology.
Biomarkers of the Tumour Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.