Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are.
The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people.
Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. It will change both our view of nature and our sense of where we belong in it.
Stanford University’s Justin and Erica Sonnenburg are pioneers in the most exciting and potentially transformative field in the entire realm of human health and wellness, the study of the relationship between our bodies and the trillions of organisms representing thousands of species to which our bodies play host, the microbes that we collectively call the microbiota. The microbiota interacts with our bodies in a number of powerful ways; the Sonnenburgs argue that it determines in no small part whether we’re sick or healthy, fit or obese, sunny or moody. The microbiota has always been with us, and in fact has coevolved with humans, entwining its functions with ours so deeply, the Sonnenburgs show us, humans are really composite organisms having both microbial and human parts. But now, they argue, because of changes to diet, antibiotic over-use, and over-sterilization, our gut microbiota is facing a “mass extinction event,” which is causing our bodies to go haywire, and may be behind the mysterious spike in some of our most troubling modern afflictions, from food allergies to autism, cancer to depression. It doesn’t have to be this way.
The Good Gut offers a new plan for health that focuses on how to nourish your microbiota, including recipes and a menu plan. In this groundbreaking work, the Sonnenburgs show how we can keep our microbiota off the endangered species list and how we can strengthen the community that inhabits our gut and thereby improve our own health. The answer is unique for each of us, and it changes as you age.
In this important and timely investigation, the Sonnenburgs look at safe alternatives to antibiotics; dietary and lifestyle choices to encourage microbial health; the management of the aging microbiota; and the nourishment of your own individual microbiome.
Caring for our gut microbes may be the most important health choice we can make.
From the Hardcover edition.
“Fascinating—and full of the kind of factoids you can't wait to share.” —Scientific American
Parasites can live only inside another animal and, as Kathleen McAuliffe reveals, these tiny organisms have many evolutionary motives for manipulating the behavior of their hosts. With astonishing precision, parasites can coax rats to approach cats, spiders to transform the patterns of their webs, and fish to draw the attention of birds that then swoop down to feast on them. We humans are hardly immune to their influence. Organisms we pick up from our own pets are strongly suspected of changing our personality traits and contributing to recklessness and impulsivity—even suicide. Germs that cause colds and the flu may alter our behavior even before symptoms become apparent.
Parasites influence our species on the cultural level, too. Drawing on a huge body of research, McAuliffe argues that our dread of contamination is an evolved defense against parasites. The horror and revulsion we are programmed to feel when we come in contact with people who appear diseased or dirty helped pave the way for civilization, but may also be the basis for major divisions in societies that persist to this day. This Is Your Brain on Parasites is both a journey into cutting-edge science and a revelatory examination of what it means to be human.
“If you’ve ever doubted the power of microbes to shape society and offer us a grander view of life, read on and find yourself duly impressed.” —Heather Havrilesky, Bookforum
Knowledge flow- A mobile learning platform provides Apps and Books.
Knowledge flow provides learning book of Basics of Microbiology. This book is for all science students and professional across the world. Microbiology is the microscopic study of micro-organism like bacteria, viruses and protozoa. To understanding better key concepts of microbiology this book of microbiology is very helpful with effective illustrations.
1. Introduction to Microbiology
2. Morphology of bacteria
3. Reproduction and Growth
4. Enzymes and their Regulations
5. Microbial Metabolism
6. Bacterial Genetics
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Designed specifically to meet the needs of the students pursuing undergraduate courses in Medical, Dental, Physiotherapy, Nursing, Pharmacy and Science.Maintained the basic pattern, followed for text in question–answer format which helps the students in quick learning and revision
Newer developments and revisions to keep up the text with the latest changes as per the undergraduates’ curriculum.
More emphasis on systemetic presentation of information, helps to recollect the things easily
New to this Edition
Merged Parasitolgy section with Microbiology section within same page range in single book
Addition of many new coloured figures to facilitate greater retention of knowledge. Also replacement of earlier figures with newer coloured figures to make understanding better
Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical care. Case Files: Microbiology provides 54 true-to-life cases that illustrate essential concepts in this field. Each case includes an easy-tounderstand discussion correlated to essential basic science concepts, definitions of key terms, microbiology pearls, and USMLE-style review questions. With Case Files, you'll learn instead of memorize.Learn from 54 high-yield cases, each with board-style questions and key-point pearls Master complex concepts through clear and concise discussions Practice with review questions to reinforce learning Polish your approach to clinical problem-solving Perfect for medical and dental students preparing for course exams and the Boards
—Kirkus Reviews (starred review)
"Teeming with information and big ideas... Outstanding.”
—Booklist (starred review)
The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases.
The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies—a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases—which now account for 63 percent of all human deaths.
Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.
From the Hardcover edition.
Kenneth D. Somers, Ph.D. Eastern Virginia Medical School, Norfolk, VA, and Stephen Morse, Center for Infectious Diseases, Center of Disease Control, Atlanta GA
Thoroughly revised information.
Key Points highlighting the need to know aspects of the discussed topics.
Tables and figures for better understanding.
Case studies at the end of chapters for self-assessment.
Special emphasis on emerging and re-emerging pathogens and antimicrobial resistance.
Color photographs to aid in better understanding.
Covers recent advances in molecular diagnosis and vaccines.
Rob DeSalle and Susan Perkins illuminate the long, intertwined evolution of humans and microbes. They discuss how novel DNA sequencing has shed entirely new light on the complexity of microbe-human interactions, and they examine the potential benefits to human health: amazing possibilities for pinpoint treatment of infections and other illnesses without upsetting the vital balance of an individual microbiome.
This book has been inspired by an exhibition, The Secret World Inside You: The Microbiome, at the American Museum of Natural History, which will open in New York in early November 2015 and run until August 2016. It will then travel to other museums in the United States and abroad.
Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics.
In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years.
Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy, and how to implement their use successfully. Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.
The Forgotten Cure traces the story of phages from Paris, where they were discovered in 1917; to Tbilisi, Georgia, where one of phage therapy’s earliest proponents died at the hands of Stalin; to the Nobel podium, where prominent scientists have been recognized for breakthroughs stemming from phage research. Today, a crop of biotech startups and dedicated physicians is racing to win regulatory approval for phage therapy before superbugs exhaust the last drug in the medical arsenal. Will they clear the hurdles in time?
Easily find and cross-reference information through a detailed table of contents that highlights clinical examples in red.
Review material quickly using pedagogical features, such as Essential Concept boxes, bolded words, and key clinical terms marked in red, that emphasize key details and reinforce your learning.
Integrate cell biology and histology with pathology thanks to vivid descriptive illustrations that compare micrographs with diagrams and pathological images.Apply the latest developments in pathology through updated text and new illustrations that emphasize appropriate correlations.
Expand your understanding of clinical applications with additional clinical case boxes that focus on applying cell and molecular biology to clinical conditions.
Effectively review concepts and reinforce your learning using new Concept Map flow charts that provide a framework to illustrate the integration of cell-tissue-structure-function within a clinical-pathology context.
Includes more than 20 case studies
The twenty-seventh edition of Jawetz, Melnick & Adelberg’s Medical Microbiology delivers a concise, up-to-date overview of the roles microorganisms play in human health and illness. Linking fundamental principles with the diagnosis and treatment of microbial infections, this classic text has been updated throughout to reflect the tremendous expansion of medical knowledge afforded by molecular mechanisms, advances in our understanding of microbial pathogenesis, and the discovery of novel pathogens.
Along with brief descriptions of each organism, you will find vital perspectives on pathogenesis, diagnostic laboratory tests, clinical findings, treatment, and epidemiology. The book also includes an entire chapter of case studies that focuses on differential diagnosis and management of microbial infections.
Here’s why Jawetz, Melnick & Adelberg’s Medical Microbiology is essential for USMLE review:650+ USMLE-style review questions 300+ informative tables and illustrations 23 case studies to sharpen you differential diagnosis and management skills An easy-to-access list of medically important microorganisms Coverage that reflects the latest techniques in laboratory and diagnostic technologies Full-color images and micrographs Chapter-ending summaries Chapter concept checks
Jawetz, Melnick & Adelberg’s Medical Microbiology introduces you to basic clinical microbiology through the fields of bacteriology, virology, mycology, and parasitology, giving you a thorough yet understandable review of the discipline.
The book offers a broad spectrum of topics trending in the food industry, such as pharmaceutical, biomedical, and antimicrobial approaches in food, highlighting current concerns regarding safety, regulations, and the restricted use of nanomaterials.Includes how nanobiosensors are useful for the detection of foodborne pathogensDiscusses applications of nanotechnology from flavor and nutrition, to stability and safety in packagingIncludes nano and microencapsulation, nanoemulsions, nanosensors, and nano delivery systemsIdentifies practical applications of nanoscience for use in industry today
Review questions at the end of each chaptercorrelate basic science with clinical practice to help you understand the clinical relevance of the organisms examined.
Clinical casesillustrate the epidemiology, diagnosis, and treatment of infectious diseases, reinforcing a clinical approach to learning.
Full-color clinical photographs, images, and illustrations help you visualize the clinical presentations of infections.
Summary tables and text boxes emphasizing essential concepts and learning issuesoptimize exam review.
Additional images, 200 self-assessment questions, NEW animations,and more. Thoroughly updated chapters include the latest information on the human microbiome and probiotics/prebiotics; including a new chapter on Human Microbiome In Health and Disease
NEW chapter summariesintroduce each microbe chapter, including trigger words and links to the relevant chapter text (on e-book version on Student Consult), providing a concise introduction or convenient review for each topic.
Full-color clinical photographs, images, and illustrations help you visualize the clinical presentations of infections.
Additional images, 200 self-assessment questions, NEW animations,and more.
Each card presents similar information with variations due to inherent pathogen differences. On the front is an introduction to each pathogen with clinical vignettes and images. The back provides the taxonomy or morphology, infections, pathogenesis, epidemiology, diagnosis, prevention, treatment options, and an explanation.
Key FeaturesMore than 230 graphics including full-color clinical images, pathogen photomicrographs, cell stains, biochemical tests, and diagramsSix color-coded pathogen types further facilitate quick acquisition of knowledgeOnline content via Winking Skull.com provides navigation by organ system or pathogen typePromotes long-term retention of complex materialAnimations further enhance learning
This is an essential guide for medical students preparing for the USMLE®. It is also an ideal choice for graduate-level students in health science and dentistry looking for a user-friendly microbiology review.
Case studiesmirror the USMLE’s emphasis on clinical applications.
Microbe Cards, Concept Cards,and Disease Cards provide data on microbial infections, important concepts, and an overview of infectious disease. Completely revised to correlate to Murray’s Medical Microbiology, 8th Edition.
With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future.Expertly describes the latest metagenomic methodologies and best-practices, from sample collection to data analysis for taxonomic, whole shotgun metagenomic, and metatranscriptomic studiesIncludes clear-headed pointers and quick starts to direct research efforts and increase study efficacy, eschewing ponderous prosePresented topics include sample collection and preparation, data generation and quality control, third generation sequencing, advances in computational analyses of shotgun metagenomic sequence data, taxonomic profiling of shotgun data, hypothesis testing, and mathematical and computational analysis of longitudinal data and time series. Past-examples and prospects are provided to contextualize the applications.
Now in a fully revised and updated 19th edition, Medical Microbiology provides comprehensive coverage of infection from the microbial perspective, combining a clear introduction to key principles with a focus explicitly geared to modern clinical practice. It provides ideal coverage for medical and biomedical students – with ‘Key Points’ boxes throughout to highlight the essentials – and sufficient detail to also inform specialists in training.
Building on the success of previous editions, updates in Medical Microbiology 19e include:
New and expanded coverage of hot topics and emerging areas important to clinical practice, including:
The Human Microbiome
Direct acting antiviral agents for the treatment of HCV infection
Molecular methods in diagnostic microbiology
A new and improved downloadable eBook (from studentconsult) – for anytime access to the complete contents plus BONUS interactive learning materials:
Clinical cases - to introduce how patients with infections present and help relate key principles to practice
MCQs for each chapter -to check understanding and aid exam preparation
This review summarizes in detail the contemporary knowledge of filoviruses and the diseases they cause. The entirety of the open literature on filoviruses, covering all major scientific and clinical fields, is referenced and summarized in this text, including most of the conference abstracts, book chapters, dissertations, government reports, patents, theses, and journal publications in many languages. For ease of retrieval by the reader, all references are cited with original titles in the original spelling, first author names, full journal titles, and issue numbers where possible. The text of this book and the accompanying reference resource will be updated in the future, and thus will provide a robust source of information for filovirologists, other virologists and scientists in general, clinicians, students, journalists, and biodefense professionals.
The business case for a new or refurbished food factory, its equipment needs and the impacts on factory design and construction are considered in two introductory chapters. Part one then reviews the implications of hygiene and construction regulation in various countries on food factory design. Retailer requirements are also discussed. Part two describes site selection, factory layout and the associated issue of airflow. Parts three, four and five then address the hygienic design of essential parts of a food factory. These include walls, ceilings, floors, selected utility and process support systems, entry and exit points, storage areas and changing rooms. Lastly part six covers the management of building work and factory inspection when commissioning the plant.
With its distinguished editors and international team of contributors, Hygienic design of food factories is an essential reference for managers of food factories, food plant engineers and all those with an academic research interest in the field.An authoritative overview of hygiene control in the design, construction and renovation of food factoriesExamines the implications of hygiene and construction regulation in various countries on food factory designDescribes site selection, factory layout and the associated issue of airflow
Minimalistic and simplified approach to the subject. Entire book is designed in a tabulated manner.Very useful to learn many parasites in a short period of time during exams. Comaprative design helps students to retain knowledge more effectively. Concise, bulleted format and to-the-point text-easy to read during examination. Simple and lucid language makes the understanding easy.
Supplement video tutorial link:
Grasp and retain vital concepts easilythanks to a user-friendly color-coded format, succinct text, key concept boxes, and dynamic illustrations.
Effectively review for problem-based courseswith the help of chapter introductions and "Lessons in Microbiology" text boxes that highlight the clinical relevance of the material, offer easy access to key concepts, and provide valuable review tools.
Approach microbiology by body system or by pathogenthrough an extensively cross-referenced "Pathogen Review" section.
Access the complete contents online at studentconsult.com, along with downloadable illustrations...150 multiple choice review questions... "Pathogen Parade"...and many other features to enhance learning and retention. Enhance your learning and absorb complex information in an interactive, dynamic way with Pathogen Parade – a quickly searchable online glossary of viruses, bacteria, and fungi.
Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventive medicine.A completely re-written chapter on this topic keeps abreast of the very latest findings.
Visually grasp and retain difficult concepts easilythanks to a user-friendly color-coded format, key concept boxes, explanatory diagrams, and over 190 photos to help you visualize tissues and diseases.
Put concepts into practice. "Critical Thinking Boxes" and 25 online cases encourage you to "think immunologically" while anchoring your understanding of immunology through clinical application.
Gauge your mastery of the materialand build confidence with high-yield style chapter-opening summaries and case-based and USMLE-style questions that provide effective chapter review and quick practice for your exams.
Access the full contents online at www.studentconsult.comwhere you'll find the complete text and illustrations, USMLE-style questions, clinical cases, and much more! Get the depth of coverage you need in a smaller, more manageably sized book. Through meticulous editing and reorganization, primary material remains in the book while more specialized and clinical material has been moved online.
Master the most cutting-edge concepts in immunology.Thorough updates throughout provide the timely knowledge you need ace your exams.
First, the use of lamivudine (3TC) for the treatment of HIV infections, and its more recent introduction for the treatment of hepatitis B virus (HBV) infections, has heralded the transition of D- to L-nucleosides in the antiviral nucleoside drug design, and it is likely that the future will provide more nucleosides of the L-configuration, such as (-)FFC (emtricitabine) and L-FMAU, as will be described by J.-C.G. Graciet and R.F. Shinazi.
Second, the acyclic purine nucleoside phosphonates, i.e. PMEA (adefovir and PMPA (tenofovir), offer great potential as both anti-HIV and anti-HBV agents, and both compounds have been the subject of advanced clinical trials in their oral produrg form (adefovir dipivoxil and tenofovir disoproxyl), as mentioned by M.N. Arimilli, J.P. Dougherty, K.C. Cundy, and N. Bischofberger.
Third, with the advent of nevirapine, delavirdine, and efavirenz, the NNRTIs have definitely come of age. Emivirine (MKC-442), a derivative of the original HEPT analog that was described in 1989 has now proceeded through pivotal clinical studies, and how this class of compounds evolved is presented in the account of H. Tanaka and his colleagues.
Fourth, at the end of 1999, anticipating on the next winter influenza offensive, we should have at end two compounds that specifically inhibit influenza A and B virus infections: zanamivir (by the intranasal route) and oseltamivir (by the oral route). Both compounds have proved effective in the prophylaxis and treatment of influenza A and B virus infections and act through the same mechanism; that is by blocking the viral neuraminidase (or sialidase), a key enzyme that allows the virus to spread from one cell to another (within the respiratory mucosal tract). The design of these sialidase inhibitors will be presented by M. von Itzstein and J.C. Dyason.
Fifth, the discovery (in 1996) of the chemokine receptors CXCR4 and CCR5 as essential coreceptors (in addition to the CD4 receptor) for HIV entry into the cells, has boosted an enormous interest in potential antagonists of these receptors. The bicyclams represent the first low-molecular-weight compounds targeted at CXCR4, the coreceptor used by the more pathogenic, T-lymphotropic, HIV strains, to enter the cells. They will be addressed by G.J. Bridger and R.T. Skerlj.
The five topics covered in this third volume of Advances in Antiviral Drug Design are in the front line of the present endeavors towards the chemotherapy of virus infections. They pertain to the combat against three of the most important virus infections of current times: HIV, HBV, and influenza virus.
Building on the huge success of previous editions, Medical Microbiology 18/e will inform and inspire a new generation of readers. Now fully revised and updated, initial sections cover the basic biology of microbes, infection and immunity and are followed by a systematic review of infective agents, their associated diseases and their control. A final integrating section addresses the essential principles of diagnosis, treatment and management. An unrivalled collection of international contributors continues to ensure the relevance of the book worldwide and complementary access to the complete online version on Student Consult further enhances the learning experience.
Medical Microbiologyis explicitly geared to clinical practice and is an ideal textbook for medical and biomedical students and specialist trainees. It will also prove invaluable to medical laboratory scientists and all other busy professionals who require a clear, current and most trusted guide to this fascinating field.
654 USMLE-style practice questions test your knowledge and understanding 50 clinical cases illustrate the importance of basic science in clinical diagnosis A complete USMLE-style practice exam consisting of 80 questions Pearls for the USMLE impart important basic science information
Essential for USMLE and medical microbiology course exam preparation, the Fourteenth Edition of Review of Medical Microbiology and Immunology helps you understand the clinical relevance of microbiology like no other resource. The book presents a succinct, high-yield review of the medically important aspects of microbiology and immunology, covering both the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology. It also discusses important infectious diseases using a logical organ system approach.
Review of Medical Microbiology and Immunology, Fourteenth Edition emphasizes the real-world clinical application of microbiology and immunology to infectious diseases and offers a unique mix of narrative text, color images, tables and figures, chapter-ending self-assessment questions with answers, and clinical cases. To further reinforce learning, the book includes concise summaries of medically important microorganisms; a color art program that depict clinically important findings; gram stains of bacteria; electron micrographs of viruses; and microscopic images highlighting fungi, protozoa, and worms.
The health aspects of milk, its role in the diet and milk-based functional foods are the focus of the opening section of Volume 2. Part two reviews essential aspects of milk quality, including milk microbial spoilage and chemical deterioration, sensory evaluation, factors affecting milk vitamin and mineral content and the impact of packaging on quality. Chapters in part three look at improving particular products, such as organic milk, goat milk and sheep milk. The impact of milk on the quality of yoghurt and cheese is also covered.
With its distinguished editor and international team of contributors, volume 2 of Improving the safety and quality of milk is an essential reference for researchers and those in industry responsible for milk safety and quality.Examines the sensory and nutritional quality of cow's milk and addresses quality improvement of a range of other milk-based productsReviews the health aspects of milk and its role in the diet, as well as the essential aspects of milk quality, including microbial spoilage and chemical deterioration, sensory evaluation and factors affecting milk vitamin and mineral contentDiscusses various application requirements of milk such as milk quality requirements in yoghurt-making, cheesemaking, infant formulas and applications of milk components in products other than foods
The first section covers how micro-organisms spread and cause disease in humans, and how the human body responds to infection in general. The next three sections give a broad outline of the important properties of human infectious pathogens; split into viruses, bacteria, and eukaryotic organisms. The final sections cover laboratory diagnosis, antimicrobial chemotherapy, prevention strategies, and infection from the point of view of the patient.