the drama of the front lines.”
-Richard Danzig, former secretary of the navy
The first major bioterror event in the United States-the anthrax attacks in October 2001-was a clarion call for scientists who work with “hot” agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.
Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.
Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.
Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.
Every brain begins as a female brain. It only becomes male eight weeks after conception, when excess testosterone shrinks the communications center, reduces the hearing cortex, and makes the part of the brain that processes sex twice as large.
Louann Brizendine, M.D. is a pioneering neuropsychiatrist who brings together the latest findings to show how the unique structure of the female brain determines how women think, what they value, how they communicate, and whom they’ll love. Brizendine reveals the neurological explanations behind why
• A woman remembers fights that a man insists never happened
• A teen girl is so obsessed with her looks and talking on the phone
• Thoughts about sex enter a woman’s brain once every couple of days but enter a man’s brain about once every minute
• A woman knows what people are feeling, while a man can’t spot an emotion unless somebody cries or threatens bodily harm
• A woman over 50 is more likely to initiate divorce than a man
Women will come away from this book knowing that they have a lean, mean communicating machine. Men will develop a serious case of brain envy.
Why do you fall in love with one person rather than another? In this fascinating and informative book, Helen Fisher, one of the world's leading experts on romantic love, unlocks the hidden code of desire and attachment. Each of us, it turns out, primarily expresses one of four broad personality types—Explorer, Builder, Director, or Negotiator—and each of these types is governed by different chemical systems in the brain. Driven by this biology, we are attracted to partners who both mirror and complement our own personality type.
Until now the search for love has been blind, but Fisher pulls back the curtain and reveals how we unconsciously go about finding the right match. Drawing on her unique study of 40,000 men and women, she explores each personality type in detail and shows you how to identify your own type. Then she explains why some types match up well, whereas others are problematic. (Note to Explorers: be prepared for a wild ride when you hitch your star to a fellow Explorer!) Ultimately, Fisher's investigation into the complex nature of romance and attachment leads to astonishing new insights into the essence of dating, love, and marriage.
Based on entirely new research—including a detailed questionnaire completed by seven million people in thirty-three countries—Why Him? Why Her? will change your understanding of why you love him (or her) and help you use nature's chemistry to find and keep your life partner.
updated and streamlined for today’s students and clinicians
The only place you can get ALL the great content found in the two print volumes AND the acclaimed DVD in one convenient resource!
Through six decades, no resource has matched the authority, esteemed scholarship, and scientific rigor of Harrison’s Principles of Internal Medicine. Capturing the countless advances and developments across the full span of medicine, the new 19th edition of Harrison’s provides a complete update of essential content related to disease pathogenesis, clinical trials, current diagnostic methods and imaging approaches, evidence-based practice guidelines, and established and newly approved treatment methods.
Here are just a few of the outstanding features of the new Nineteenth Edition:Content is practically organized around two basic themes: education and clinical practice The teaching and learning sections cover foundational principles, cardinal manifestations of disease and approach to differential diagnosis; the content devoted to clinical practice focuses on disease pathogenesis and treatment NEW chapters on important topics such as Men’s Health, The Impact of Global Warming on Infectious Diseases, Fatigue, and many more Critical updates in management and therapeutics in Hepatitis, Coronary Artery Disease, Ebola Virus Disease, Multiple Sclerosis, Diabetes, Hypertension, Deep Vein Thrombosis and Pulmonary Embolism, Acute and Chronic Kidney Disease, Inflammatory Bowel Disease, Lipoprotein Disorders, HIV and AIDS, and more. Increased number of the popular Harrison’s clinical algorithms; clinically relevant radiographic examples spanning hundreds of diseases; clinical-pathological images in full color; crystal clear, full color drawings and illustrations and helpful tables and summary lists that make clinical application of the content faster than ever Outstanding multi-media resources including practical videos demonstrating essential bedside procedures, physical examination techniques, endoscopic findings, cardiovascular findings, are available for easy download
Supporting the renowned coverage are supplemental resources that reflect and assist modern medical practice: more than 1,000 full-color photographs to aid visual recognition skills, hundreds of state-of-the-art radiographs, from plain film to 3D CT to PET Scans; beautiful illustrations that bring applied anatomy and processes to life; the renowned Harrison’s patient-care algorithms, essential summary tables, and practical demonstrative videos. In addition, several digital atlases highlight noninvasive imaging, percutaneous revascularization, gastrointestinal endoscopy, diagnosis and management of vasculitis, and numerous other issues commonly encountered in clinical practice.
Acclaim for Harrison’s:
“Covering nearly every possible topic in the field of medicine, the book begins with a phenomenal overview of clinical medicine, discussing important topics such as global medicine, decision-making in clinical practice, the concepts of disease screening and prevention, as well as the importance of medical disorders in specific groups (e.g. women, surgical patients, end of life). The extensive chapters that follow focus on a symptom-based presentation of disease and then illness organized by organ system. Numerous tables, graphs, and figures add further clarity to the text."
...Written by experts in the field, this book is updated with the latest advances in pathophysiology and treatment. It is organized in a way that makes reading from beginning to end a logical journey, yet each chapter can stand alone as a quick reference on a particular topic. “
Doody’s Review Service reviewing the previous edition of Harrison’s
Includes 6 online-only chapters at no additional cost! Go to: www.AccessMedicine.com/CMDT
The book that puts the latest research where it belongs . . . into your practiceWritten by clinicians renowned in their respective fields, CMDT offers the most current insight into symptoms, signs, epidemiology, and treatment for more than 1,000 diseases and disorders. For each topic, you’ll find concise, evidence-based answers to questions about hospital and ambulatory medicine. This streamlined clinical companion is the fastest and easiest way to keep abreast of the latest medical advances, prevention strategies, and cost-effective treatments.
Features and content critical to clinical practice: Strong emphasis on the practical aspects of clinical diagnosis and patient management in all fields of internal medicine Full review of all internal medicine and primary care topics, including gynecology and obstetrics, dermatology, neurology, ophthalmology, geriatrics, and palliative care The only text with an annual review of advances in HIV treatment Specific disease prevention information Drug treatment tables, with indexed trade names and updated prices – plus helpful diagnostic and treatment algorithms Recent references with PMID numbers Six online-only chapters available at no additional cost Full-color photographs and illustrations
NEW TO THIS EDITION: New chapter on Sports Medicine & Outpatient Orthopedics Extensive revision of medical and surgical conditions of pregnancy Updated coverage of evaluating fertility in women, immunization requirements, and the use and safety of nonsteroidal and anti-inflammatory drugs Extensive revision of Kidney Disease chapter New topics include snoring a selection of common musculoskeletal problems such as subacromial impingement syndrome, rotator cuff tear, anterior cruciate ligament and meniscus injuries, patellofemoral pain syndrome, and inversion and eversion ankle sprains New online-only chapter on Women’s Health Issues S.I. units used throughout
Visit CMDT2012.com or join the conversation at #CMDT
Complement your understanding of new words and ideas in medicine with 500 new illustrations
Get more information in a smaller amount of space as the revised entry format includes related parts of speech.
Topics covered include Cardiovascular Disease, Endocrinology & Metabolism, Gastroenterology, General Internal Medicine, Hematology, Infectious Disease, Nephrology / Urology, Oncology, Neurology, Dermatology, Pulmonary Disease & Critical Care, Rheumatology / Orthopedics
The book also contains 2 bonus chapters on how to study for the ABIM Internal Medicine Exam and the NBME Internal Medicine Shelf Exam.
For more information visit www.knowmedge.com
Stay up-to-date in the area of treatment and management with enhanced discussions throughout.
Be familiar with the most current developments and information in family medicine with this all-around review of the specialty, ideal for nurses and PAs!Assess your mastery of the latest diagnostic methods and management techniques through hundreds of questions and dozens of cases, newly updated to reflect the most current developments in practice.
Browse the full text, review questions, images, and tips for passing the exam online at www.expertconsult.com.
Earn up to 89 hours of AMA Category 1 Physician's Recognition Award CME Credit online through Robert Wood Johnson Medical School.
Access the text clearly on any device with a new eReader-compatible design.
Quickly grasp the fundamentals you need to know through easy-access bulleted text and more than 700 images.
Arrive at diagnoses by following a pattern recognition approach, and logically overcome difficult diagnostic challenges with the aid of decision trees.
Learn from the best, as Dr. Herring is both a skilled radiology teacher and the host of his own specialty website, www.learningradiology.com. Easily master the fundamental principles of MRI, ultrasound, and CT with new chapters that cover principles of each modality and the recognition of normal and abnormal findings.
A companion Website will include the fully searchable text, an image bank, an interactive question bank, and an EKG image with explanation test bank.
Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.
Stay on top of the latest procedures and treatment guidelines with updated coverage of 184 topics, including Swimmers Ear, Dental Pain, Broken Rib, Locked Knee, Puncture Wounds, and Sunburn.Get procedural sedation recommendations from Dr. Alfred Sacchetti, MD, FACEP.
This practical, comprehensive text serves as a step-by-step, hands-on workbook for those learning to interpret 12-Lead EKGs. With over 45 years of experience in cardiac care, authors Green and Chiaramida present the content and technical understanding students need to accurately analyze, interpret, and comprehend the variety of rhythm strips that make up 12-lead EKGs.
This book introduces basic principles of anatomy and physiology, including a review of the heart's electrical system. The chapters discuss vital elements of cardiology, such as atrial and ventricular arrhythmias, conduction abnormalities and heart block, ischemic and nonischemic disorders, and more. Explanations of terms and concepts are concise and to the point, allowing students to focus on the most important information. With this guide, medical and nursing students will gain the confidence they need to accurately interpret 12-lead EKGs.
Key Features: Self-Study Objectives listed at the start of each chapterEnlarged segments of the 12-Lead EKG rhythm strips to ensure that the student views the appropriate lead, and sees the entire 12-lead stripWorksheets at the end of each chapter, allowing students to practice measurement, evaluate and interpret rhythms, and develop diagnostic reasoning skillsA self assessment section for students at the end of the book
Davidson’s global perspective is enhanced by the input of an international team of authors and a distinguished International Advisory Board from 17 countries. Building on the foundations laid down by its original editor, Davidson’s remains one of the world’s leading and most respected textbooks of medicine.The underlying principles of medicine are described concisely in the first part of the book, and the detailed practice of medicine within each sub-specialty is described in later system-based chapters.
Most chapters begin with a two-page overview of the important elements of the clinical examination, including a manikin to illustrate the key steps in the examination of the relevant system.
A practical, problem-based clinical approach is described in the ‘Presenting Problems’ sections, to complement the detailed descriptions of each disease.
The text is extensively illustrated, with over 1000 diagrams, clinical photographs, and radiology and pathology images.
1350 text boxes present information in a way suitable for revision, including 150 clinical evidence boxes summarising the results of systematic reviews and randomised controlled trials and 65 ’In Old Age’ boxes highlighting important aspects of medical practice in the older population.
A combined index and glossary of medical acronyms contains over 10 000 subject entries. The contents can also be searched comprehensively as part of the online access to the whole book on the StudentConsult platform.
Access over 500 self-testing questions with answers linked to the book’s content for further reading.
The text uses both SI and non-SI units to make it suitable for readers throughout the globe.A new chapter specifically on Stroke Disease recognises the emergence of Stroke Medicine as a distinct clinical and academic discipline.
A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories.
New ‘In Adolescence’ boxes recognise the fact that many chronic disorders begin in childhood and become the responsibility of physicians practising adult medicine. These boxes acknowledge the overlap ‘transitional’ phase and highlight the key points of importance when looking after young people.
The regular introduction of new authors and editors maintains the freshness of each new edition. On this occasion Dr Ian Penman has joined the editorial team and 18 new authors bring new experience and ideas to the content and presentation of the textbook.
An expanded International Advisory Board of 38 members includes new members from several different countries.
More than 200 lab tests help hone your skills in reviewingnormal values and interpreting results
Electronic accessto additional algorithms, new images and tables, EBM boxes, patient teaching guides, and extra topics. Links between each section allow you to navigate easily from a selected topic to relevant associated material and back again
An expanded International Editorial Board provides increased input from respected practitioners worldwide. Excellent images and clinical photographs vividly illustrate the appearance and clinical features of disease.
Masterful editing and a user-friendly full-color design make absorbing and retaining information as effortless as possible.
"This is a very well organized, valuable tool for busy house officers to access necessary and useful information for the care of their patients."--Doody's Review Service The ON CALL Series
*Concise and portable for “on-the-spot” treatment advice
*Comprehensive overview of the initial evaluation and treatment
*Features the most frequently encountered problems in a specialty
*Includes laboratory and diagnostic tests, procedures, and commonly used medications
*Perfect for residents and students on the wards
Over 60 of the most common internal medicine problems. Thoroughly revised to include new laboratory tests and a therapeutics section with over 100 new drugs.
The famous "one disease per page" design!
CURRENT Essentials of Medicine is a practical, point-of-care pocket handbook that offers "nutshell" information on the diagnosis and treatment of more than 500 medical disorders seen in both primary care and hospital settings. Perfect as a quick reference on the wards or in a busy clinic, this is THE ONLY pocket guide to offer disease essentials in a one-disease-per-page bulleted format. Practical pearls, for which the authors are well known, are offered for almost all conditions.
Skim the "Top 100 Secrets" and "Key Points" boxes for a fast overview of the secrets you must know for success on the boards and in practice.
Enjoy faster, easier review and master the top issues in nephrology with mnemonics, lists, quick-reference tables, and an informal tone that sets this review book apart from the rest.
Carry it with you in your lab coat pocket for quick reference or review anytime, anywhere. Handle each clinical situation with confidence with chapters completely updated to reflect the latest information.
Find the answers you need faster thanks to a new, more streamlined and problem-based organization.
Brain Injury Medicine, 2nd Edition Features:The acknowledged gold standard reference-brings together knowledge, experience, and evidence-based medicineComprehensive and current-completely revised, updated, and expanded to include emerging topics and the latest clinical and research advances Multi-disciplinary focus-expert authorship from a wide range of specialties promotes a holistic team approach to a complex, many-faceted condition Covers the entire continuum of care from early diagnosis and assessment through acute management, rehabilitation, associated medical and quality of life issues, and functional outcomes
New to the Second Edition:Three new Associate Editors from related disciplines provide added expertise Five new sections: acute rehabilitative care, pediatric TBI, special senses, autonomic and other organ system problems, post-trauma pain disorders 25 new chapters running the gamut from health policy to biomechanics, to military TBI to pediatric issues and more Print + Digital Access: Purchase price includes enhanced e-book containing the complete and fully searchable text plus additional digital-only content
• New understandings gained by five years of additional research on Parkinson’s disease• New focus on the importance of exercise• New information about imaging techniques such as SPECT Scan and DATScan that are aiding in the diagnosis• New findings about the genetics of the disease• Promising uses of new technologies such as tablet devices for people who have trouble communicating• Information about impulse control disorders caused by some drugs used to address the symptoms of the disease• A complete update on treatments such as medications, surgery, and more
Nessa Carey, a leading epigenetics researcher, connects the field’s arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
CURRENT Medical Diagnosis and Treatment Flashcards contains 250 flashcards drawn from the pages of the core CMDT text that facilitate your analysis of test cases and enhances your recall of internal medicine topics. Included in this handy, quick-reference sourcebook are all topics within the Internal Medicine Clerkship Curriculum, as well as additional material pertaining to CMDT coverage. Organized according the Core Curriculum of the Clerkship Directors in Internal Medicine, the flashcards cover over 30 core topics that encompass fundamental concepts, common conditions, presentations, treatment approaches, and diseases seen by general practitioners in the inpatient and outpatient settings.
The flashcards utilize content from CMDT, Quick Answers, and Lange Pathophysiology to provide a case-based application that tests key concepts in clinical reasoning, clinical problem-solving, and recognition of essential clinical facts. The second edition of CURRENT Medical Diagnosis and Treatment Flashcards features updated, refreshed content throughout, making it the most indispensable—and current—clerkship prep tool available. Now more than ever, it’s required reading for every medical and nursing student, physician assistant, nurse practitioner, house officer, and practicing physician.Extensive content updating to the flashcards Cross-referenced to the CMDT book in the flashcard references to point you to relevant content in the most recent edition of the book Questions cover salient features; how to think through the problem; essentials of diagnosis; symptoms and signs; differential diagnosis; laboratory, imaging, and procedural findings; treatment modalities; and more
Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 19th edition, is a completely revised and updated guide to help you prepare for your primary board certification, maintenance of certification/re-certification, and for in-service exams. An important component of the Harrison’s set, this review reflects all of the most up-to-date material featured in the 19th edition of Harrison's Principles of Internal Medicine.
This ultimate study partner contains more than 1000 revised and updated questions (and answers), simulating those on the primary certification exam. Integral to interactive self-assessment and in line with the core Harrison’s text, the high-yield content reflects the weighting of subject matter included on the internal medicine board exam blueprint and spans the field of internal medicine.
Get expert advice from Dr. Steven McGee, an internationally respected authority in physical examination and assessment, pain management, and education in general internal medicine.
See exactly which studies document the significance of various findings thanks to thousands of up-to-date references. Apply the latest knowledge on hot topics such as the value of physical examination in taking care of the ICU patient, accurately diagnosing the etiology of systolic murmurs, diagnosing osteoarthritis and acute vertigo in the dizzy patient, diagnosing hemorrhagic stroke, and diagnosing pleural effusions.
Implement the most current evidence-based approaches for evaluating stance and gait, Schamroths sign (for clubbing), dementia, prediction of falls, hepatopulmonary syndrome, atrial fibrillation, relative bradycardia, tourniquet test (for dengue infections), acute stroke, and pleural effusion.
Assess the pretest probability of disease, given particular signs or symptoms, with new at-a-glance tables.
Make effective decisions thanks to updated content throughout, including new EBM boxes covering over 250 recent studies on physical diagnosisensuring that all diagnostic information (i.e., sensitivity, specificity, and likelihood ratios) is up to date.
Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.
Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.
The book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field.Provides an understanding of the theoretical principles important for biological NMR spectroscopyDemonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experimentsAllows for the capability of designing effective experimental protocols for investigations of protein structures and dynamicsIncludes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods
Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word “gene” and has engendered a bitter battle over whether or not this genomic “nonsense” is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey’s book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field.
• Comprehensive guide to neurology and neurosurgery for medical students and junior doctors – competing books do not cover both areas.
• Graphic approach to the subject – concise text is arranged around clear and memorable line diagrams. Readers find this approach accessible and easy to learn form.
• Clarifies a subject area which students tend to find difficult and forbidding.
Updated and revised in all areas where there have been developments in understanding of neurological disease and in neurological and neurosurgical management. This revision has also incorporated current guidelines, particularly recommendations from National Institute for Health and Clinical Excellence (NICE).
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Much of the time, I have sensed a frustration from them. Sometimes it’s a frustration that they can’t figure out how to help me and sometimes it feels like a cumulative frustration from all the others they haven’t been able to help. But sometimes I feel that their frustration is directed to me personally, as if they wished I would just get myself together and “feel better.” Lord knows, I haven’t always made the best choices for my health.
When I saw Scott Webb, I felt a lack of that frustration and no hint of blame. It was evident to me that he saw the big picture and how we have been affected by our culture. Scott’s message was truly one of hope which brought me a sense of relief and peace. That is definitely a place where healing can begin, when you feel no blame, just peace and hope.” -- Victoria Lovett
One of America’s leading colonic therapists gives you the inside scoop on digestive disorders that you or a loved one might be experiencing. Learn how to:
• cleanse your colon and your whole body,
• reduce your risk of common diseases,
• understand the deeper issues of weight loss,
• beat underlying causes of depression,
• improve your diet to overcome constipation,
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Scott W. Webb dares to defy conventional wisdom about health and proves beyond a shadow of a doubt that he knows the “inside poop” about many secrets you have not heard yet -- until now!
Each topic includes a list of all potential causes of the condition, colour coded to indicate common, occasional or rare causes. Important geographical variations are also highlighted.
Two sections cover the differential diagnosis of biochemical and haematological disorders which provide a ready check when reviewing abnormal results
The text includes a targeted guide to the relevant general and specific follow-up investigations which should be carried out as appropriate.
At the end of each topic a box highlights important learning points, or indicates symptom and signs suggestive of significant pathology which require urgent action.Eighty colour photographs of key clinical presentations have been added to assist symptom recognition.
Two new chapters on Hypotension and Photophobia.