Pathology of Challenging Melanocytic Neoplasms offers a dynamic text where readers will encounter a broad spectrum of challenging melanocytic lesions, both benign and malignant and will thereby acquire a solid, working knowledge that they can immediately apply to daily diagnosis. The authors aim to clarify this often thorny field, keeping a steady focus on patient-related issues. The volume emphasizes the practical application of basic morphologic principles, immunohistochemistry and molecular methods in order to secure a confident diagnosis. Abundant illustrations display the characteristic features of the most important disease entities.
Rather than being yet another encyclopedic work of reference, this volume takes a fresh approach as it resembles a series of stimulating seminars employing exemplary case material to highlight, illustrate, and succinctly discuss the key points. To this end, the reader will be guided through a series of paired cases that pose a significant diagnostic challenge. By comprehensively comparing and contrasting two related entities, each such chapter will illuminate an intellectual pathway through which an important diagnostic puzzle can be solved. To broaden the differential diagnosis even further, additional illustrative cases are added to each discussion. Algorithms and tables summarize key points. Clinically relevant, up-to-date references will be provided to guide further study. Written by experts in the field, this novel text will be of great value to surgical pathologists in practice and dermatologists as well as residents and fellows training in these specialties.
Just two months before the September 11 terrorist attacks, Dr. Judy Melinek began her training as a New York City forensic pathologist. While her husband and their toddler held down the home front, Judy threw herself into the fascinating world of death investigation—performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy’s two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines Flight 587.
An unvarnished portrait of the daily life of medical examiners—complete with grisly anecdotes, chilling crime scenes, and a welcome dose of gallows humor—Working Stiff offers a glimpse into the daily life of one of America’s most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies—and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on television to reveal the secret story of the real morgue. “Haunting and illuminating...the stories from her average workdays…transfix the reader with their demonstration that medical science can diagnose and console long after the heartbeat stops” (The New York Times).
Presents information in a concise, at-a-glance format.
Fits into your pocket, for a convenient reference any time.
Offers abundant page references to the parent text, making additional information easy to find.Completely updated to reflect the latest knowledge and techniques across all areas of pathology.
We all have a rage circuit we can’t fully control once it is engaged as R. Douglas Fields, PhD, reveals in this essential book for our time. The daily headlines are filled with examples of otherwise rational people with no history of violence or mental illness suddenly snapping in a domestic dispute, an altercation with police, or road rage attack. We all wish to believe that we are in control of our actions, but the fact is, in certain circumstances we are not. The sad truth is that the right trigger in the right circumstance can unleash a fit of rage in almost anyone.
But there is a twist: Essentially the same pathway in the brain that can result in a violent outburst can also enable us to act heroically and altruistically before our conscious brain knows what we are doing. Think of the stranger who dives into a frigid winter lake to save a drowning child.
Dr. Fields is an internationally recognized neurobiologist and authority on the brain and the cellular mechanisms of memory. He has spent years trying to understand the biological basis of rage and anomalous violence, and he has concluded that our culture’s understanding of the problem is based on an erroneous assumption: that rage attacks are the product of morally or mentally defective individuals, rather than a capacity that we all possess.
Fields shows that violent behavior is the result of the clash between our evolutionary hardwiring and triggers in our contemporary world. Our personal space is more crowded than ever, we get less sleep, and we just aren't as fit as our ancestors. We need to understand how the hardwiring works and how to recognize the nine triggers. With a totally new perspective, engaging narrative, and practical advice, Why We Snap uncovers the biological roots of the rage response and how we can protect ourselves—and others.
From the Hardcover edition.
Stem Cell Research For Dummies offers a balanced,plain-English look at this politically charged topic, cutting awaythe hype and presenting the facts clearly for you, free fromdebate. It explains what stem cells are and what they do, thelegalities of harvesting them and using them in research, thelatest research findings from the U.S. and abroad, and theprospects for medical stem cell therapies in the short and longterm.Explains the differences between adult stem cells andembryonic/umbilical cord stem cellsProvides both sides of the political debate and the pros andcons of each side's opinionsIncludes medical success stories using stem cell therapy andits promise for the future
Comprehensive and unbiased, Stem Cell Research ForDummies is the only guide you need to understand this volatileissue.
Includes New and Updated Material
Now in its second edition, this work is the culmination of research and discussions with technical experts, as well as USP and FDA representatives on various topics of interest to the pharmaceutical microbiologist and those responsible for the microbial quality of products, materials, equipment, and manufacturing facilities. New in this edition is an entire chapter dedicated to the topic of biofilms and their impact on pharmaceutical and biopharmaceutical operations. The subject of rapid methods in microbiology has been expanded and includes a discussion on the validation of alternative microbiological methods and a case study on microbial identification in support of a product contamination investigation.
Substantially updated and revised, this book assists readers in understanding the fundamental issues associated with pharmaceutical microbiology and provides them with tools to create effective microbial contamination control and microbial testing programs for the areas under their responsibility.
It is now evident that the "illegal biologicals" he referred to included the pathogenic agents which have led to the AIDS epidemic and other world health crisis.
In The Extremely Unfortunate Skull Valley Incident the authors trace history of the secret war against and the terrible experiments performed upon their own citizens as well as the Third World populations. But Skull Valley does more than that. In their research the father-son team discovered the links between AIDS and many other diseases now increasing dramatically worldwide. Chief among these is myalgic encephalomyelitis/fibromyalgia dismissively labelled " chronic fatigue syndrome" by the government researchers.
In addition to AIDS and ME/FM the Scotts also demonstrate the etiological links to other neurosystemic degenerative diseases such as Alzheimer's, multiple sclerosis, Parkinson's, diabetes, schizophrenia, Crohn's-colitis, etc. All are said to be "of no known cause and having no known cure". Researchers Donald and William Scott have discovered that there is a "known cause" and there may well be a cure.
The cause is a little known organism called the "mycoplasma" which has the capacity to access genetically pre-disposed cells and to destroy them by up-taking pre-formed sterols. This process is the "degeneration" which characterizes all of the diseases under study. When the cells of the endocrine system are destroyed by a sufficient concentration of mycoplasmas, the balance of the physiological balance is altered and the immune system loses its ability to defend the infected victim, and co-factors such as the human immune-deficiency virus (HIV), and those with cause pneumonia, are free to have their way, leading to full-blown AIDS.
Lange Pathology Flash Cards, Third EditionComplete coverage of all major topics covered in medical school pathology courses Each disease-specific card features a clinical vignette and details of the disorder, including: Etiology and epidemiology Pathologic or histologic findings Classic clinical presentations Current medical treatments Perfect for disease comparisons
Efficiently review a wide spectrum of topicswith page references and a parallel organization to both Robbins and Cotran Pathologic Basis of Disease and Robbins Basic Pathology, making additional information easy to locate.
Reinforce your understanding of key contentwith answers and detailed explanations for every question at the end of each chapter.
Enhance your understanding of pathophysiology and integrate pathologywith other medical disciplines by examining correlative laboratory, radiologic, and physical diagnostic data.
Visualize key pathologic concepts and conditionsand test your diagnostic skills with over 1,100 full-color images. Features new questions that reflect today’s hot topics in pathology, keeping you up to date. Includes many new illustrations to enhance visual guidance. Uses a new chapter arrangement to conform to the new Table of Contents in Robbins and Cotran Pathologic Basis of Disease, 8th Edition, for easier cross referencing.
This may come as a surprise to you: eczema is one of the most treatable skin conditions known to man.
A big percentage of eczema sufferers feel that their skin condition will be bothering them forever - this is simply not true. When you know how to identify the triggers of eczema and how to remove these common triggers, the eczema actually heals on its own.
Here Are Three Good Reasons To Why You Can Start Curing Your Eczema Naturally Today
ONE: Eczema can be caused by both internal and external factors - examples of external factors include the use of detergents and even the weather.
TWO: Simple lifestyle changes can actually resolve your eczema.
THREE: Key changes in your diet can have an immense, beneficial effect on your eczema.
Here is something dermatologists don't want you to know: naturally remedying eczema is extremely simple. You just need to know what to do, and how to do it! Even if you're a total beginner and haven't got a clue where to start, you can start treating your eczema at home within the day!
There are essentially 3 main things you need to know about naturally curing eczema:
1. How to identify the actual symptoms of eczema and how to differentiate eczema from more serious skin conditions
2. How to identify the key triggers of eczema
3. How to remove the key triggers so that your eczema will resolve on its own
"Eczema No More" covers all of this, and a lot more. And when you read it, you'll be BLOWN AWAY with how simple it really is to naturally treat your eczema.
Here's just a taste of what you'll discover...
- How to identify the symptoms of eczema with these 3 simple techniques...
- 3 little known, yet simple ways to distinguish eczema from other skin conditions...
- 6 time tested and proven strategies for clearer and healthier skin - free from itching and soreness...
- Secret of expert skin care that few people ever know about...
- 3 proven steps to improve your skin care regimen at home...
- How to create the perfect environment for your skin during bathtime...
- 2 simple keys (that are right in front of your eyes) to avoid triggering an eczema outbreak...
- WARNING: 3 things you should never do when it comes to your own diet...
- How to cure eczema in children...
- You'll discover in just a few short minutes how to modify your daily diet for overall better skin...
- 7 everyday but often overlooked tips and tricks for improving your lifestlye so it won't exacerbate your eczema...
- And much more...
The AJCC Cancer Staging Atlas, 2nd Edition, is an official publication of the American Joint Committee on Cancer, the recognized international leader in state-of-the-art information on cancer staging. This Atlas has been created as a companion to the updated 7th Edition of the AJCC Cancer Staging Manual, which continues to disseminate the importance of anatomical and pathological staging in the management of cancer. This state-of-the-art, invaluable 2nd Edition includes a CD containing PowerPoint slides of all illustrations, additional color, and a user-friendly, easy-to-read layout. The AJCC Cancer Staging Atlas, 2nd Edition will serve as an indispensable reference for clinicians, registrars, students, trainees, and patients.
Vitamin D deficiency is the most common medical condition in the world. In America alone, over 200 million people lack sufficient levels of vitamin D and may consequently suffer from chronic health conditions, ranging from daily annoyances like fatigue and pain to life-threatening illnesses such as diabetes, heart disease, and cancer. But few people know why vitamin D is so important and what they can do to avoid the myriad ailments associated with deficiency, including heart disease, cancer, and osteoporosis.
There is no better person to demystify this vitamin and showcase its place in human health than author Michael F. Holick, M.D., Ph.D.-the father of modern vitamin D research. With more than three decades spent studying the relationship between vitamin D, limited sun exposure, and human well-being, Dr. Holick shares his findings on how combining the natural curative properties of the sun along with small lifestyle changes can help everyone to live a substantially healthier life.
Armed with a three-step plan incorporating safe amounts of sun exposure, the right supplementation, and eating foods rich in vitamin D, Dr. Holick provides prescriptive advice for anyone- from relatively healthy people to those suffering from chronic or even fatal diseases- on how to easily rebuild and maintain optimal levels of this essential hormone.
Rich with anecdotes and entertaining case studies, The Vitamin D Solution also presents research from around the world to serve as a wake-up call on this potentially lifesaving hormone for health.
Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation?
Using first-hand experience at the cutting edge of science, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge illustrates one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe.
Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden describe the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.
– Winner, Stephen Hawking Medal for Science Communication
Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before.
In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility.
Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging.
Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell’s ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body’s trillions of cells.
But some of our cells don’t age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young.
The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade.
The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.
Grasp the connections between basic science and clinical medicine with clinicopathologic correlations throughout.Learn core concepts quickly and efficiently with a highly templated design that highlights pathogenesis and morphology.
Artwork revised and updated for a more modern look and more three-dimensional feel
Targeted Therapy boxes – provides clinical information on appropriate therapy related to the disease under discussion
All photomicrographs and gross photos reviewed and improved to ensure excellent quality
Designed to complement Robbins and Cotran Pathologic Basis of Disease, 8th Edition and Robbins Basic Pathology, 8th Edition, this full-color atlas offers more than 1,500 outstanding full-color illustrations that vividly depict the diseases you need to know for pathology courses and USMLE exams. A quick visual reference or review of material for students and professionals alike.Includes gross, microscopic, and radiologic images correlated with examples of normal organs and tissues for comparison.Extensive legends summarize the key information you need to know.Correlates pathology with clinical history, physical exam findings, and clinical laboratory tests.A perfect study complement to Robbins and Cotran Review of Pathology. Includes many new and improved images.
Visually grasp and retain difficult concepts easilythanks to a user-friendly color-coded format, key concept boxes, explanatory diagrams, and over 190 photos to help you visualize tissues and diseases.
Put concepts into practice. "Critical Thinking Boxes" and 25 online cases encourage you to "think immunologically" while anchoring your understanding of immunology through clinical application.
Gauge your mastery of the materialand build confidence with high-yield style chapter-opening summaries and case-based and USMLE-style questions that provide effective chapter review and quick practice for your exams.
Access the full contents online at www.studentconsult.comwhere you'll find the complete text and illustrations, USMLE-style questions, clinical cases, and much more! Get the depth of coverage you need in a smaller, more manageably sized book. Through meticulous editing and reorganization, primary material remains in the book while more specialized and clinical material has been moved online.
Master the most cutting-edge concepts in immunology.Thorough updates throughout provide the timely knowledge you need ace your exams.
In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction.
When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection.
This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.
Laser Dermatology: Pearls and Problems is different from other laser dermatology books. Each of the five chapters begins by highlighting key points and essential concepts, then focuses on the pearls and problems for each area – based on the author’s vast experience in the field of laser dermatology. Dr. Goldberg addresses:Vascular LasersLaser Hair RemovalPigmented Lesions, Tattoos, and Disorders of HypopigmentationAblative Lasers and DevicesNon-Ablative Photorejuvenation and Skin Remodeling
Dr. Goldberg goes beyond the standard “before and after” approach to use actual images to demonstrate the pearls and pitfalls discussed in the text.
This book can be used as a text for a year long graduate course in statistics, computer science, or mathematics, for self-study, and as an invaluable research reference on probabiliity and its applications. Particularly worth mentioning are the treatments of distribution theory, asymptotics, simulation and Markov Chain Monte Carlo, Markov chains and martingales, Gaussian processes, VC theory, probability metrics, large deviations, bootstrap, the EM algorithm, confidence intervals, maximum likelihood and Bayes estimates, exponential families, kernels, and Hilbert spaces, and a self contained complete review of univariate probability.
Forensic Science Under Siege is the first book to integrate and explain these problematic trends in forensic science. The issues are timely, and are approached from an investigatory, yet scholarly and research-driven, perspective. Leading experts are consulted and interviewed, including directors of highly visible forensic laboratories, as well as medical examiners and coroners who are commandeering the discussions related to these issues. Interviewees include Henry Lee, Richard Saferstein, Cyril Wecht, and many others.
The ultimate consequences of all these pressures, as well as the future of forensic science, has yet to be determined. This book examines these challenges, while also exploring possible solutions (such as the formation of a forensic science consortium to address specific legislative issues). It is a must-read for all forensic scientists.Provides insight on the current state of forensic science, demands, and future direction as provided by leading experts in the fieldConsolidates the current state of standards and best-practices of labs across disciplinesDiscusses a controversial topic that must be addressed for political support and financial funding of forensic science to improve
Skim the Top 100 Secrets chapter and Key Points boxes for a fast overview of the secrets you must know for success on the boards and in practice.
Enjoy faster, easier review and master the top issues in dermatology with mnemonics, lists, quick-reference tables, and an informal tone that sets this review book apart from the rest.Hone your diagnostic skills with more than 500 superb full-color images throughout.
View photos in a new, expanded size for optimal visual reference.
Gain a clearer understanding of neurocutaneous melanocytosis with an entirely new section on this topic.
Access key information faster than ever with eight new tables and more than 90 new figures.
Stay current with thorough updates to both text and references in all chapters, and Web Resources added to the bibliography.
This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention.
The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.
The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression.
The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.
Thoroughly revised and up-dated edition of the standard reference work in histotechnology that successfully integrates both theory and practice.Provides a single comprehensive resource on the tried and tested investigative techniques as well as coverage of the latest technical developments.
Over 30 international expert contributors all of whom are involved in teaching, research and practice.Provides authoritative guidance on principles and practice of fixation and staining.
Extensive use of summary tables, charts and boxes.Information is well set out and easy to retrieve.
Six useful appendices included (SI units, solution preparation, specimen mounting, solubility). Provides practical information on measurements, preparation solutions that are used in daily laboratory practice.
Color photomicrographs used extensively throughout. Better replicates the actual appearance of the specimen under the microscope.
Brand new co-editors.
New material on immunohistochemical and molecular diagnostic techniques.Enables user to keep abreast of latest advances in the field.
See how to perform a variety of key procedures demonstrating endovenous radiofrequency closure, CoolTouch endovenous ablation, cross polarization visualization, PPG digital measuring, sclerotherapy of the lateral venous system showing reflux, foam sclerotherapy, telangiectatic matting, ambulatory phlebectomy, and draining of intravascular coagulum.
Apply the best practices and global perspectives from a newly reorganized team of U.S.-based and international authors and contributors.
Access the complete contents from any computer at www.expertconsult.com, complete with the full text and entire image bank.
The book begins with a general coverage of the characteristics of swine and the swine industry with emphasis on the gastrointestinal tract. It then describes the various classes of nutrients and how these nutrients are metabolized by swine and the factors affecting their utilization. The next section covers the practical aspects of swine nutrition from birth through gestation and lactation in sows and to the feeding of adult boars. The nutritional aspects of the various feedstuffs commonly fed to swine are covered in the following section. The final chapters of the book are devoted to coverage of various techniques used in swine nutrition research.
This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Third Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants are fully explored. Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter.
Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Third Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.
Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition.In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventionsEssential signaling events embedded in rich physiological and pathological contextsExtensive conceptual colour artwork to assist with comprehension of key topicsSpecial emphasis on how molecular structure determines protein function and subcellular localizationEmployment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
You'll never find an easier, more efficient, and more focused way to ace pathology and pathology-related questions on the USMLE and course examinations than USMLE Road Map. Designed to provide maximum learning in minimum time this unique review offers a concise, creative, and well-illustrated new approach to mastering pathology.
FeaturesUSMLE Shortcuts for effective USMLE preparation Outline Format with a two-color presentation guides you through the most important areas in pathology Hi-Yield Facts promote comprehension and recall Over 90 Images , including photomicrographs and clinical pictures Rapid Review Glossary defines common terms, diseases, signs, syndromes, and bodies Learning tips and tricks garnered from years of interaction with students just like you Clear explanations from instructors with the experience to know the questions you would ask