This volume is aimed at researchers and educators in imaging sciences, radiological imaging, clinical and diagnostic imaging, physicists covering different medical imaging modalities, as well as researchers in biomedical engineering, applied mathematics, algorithmic development, computer vision, signal processing, computer graphics and multimedia in general, both in academia and industry .
- Principles of intra-vascular ultrasound (IVUS)
- Principles of positron emission tomography (PET)
- Physical principles of magnetic resonance angiography (MRA).
- Basic and advanced level set methods
- Shape for shading method for medical image analysis
- Wavelet transforms and other multi-scale analysis functions
- Three dimensional deformable surfaces
- Level Set application for CT lungs, brain MRI and MRA volume segmentation
- Segmentation of incomplete tomographic medical data sets
- Subjective level sets for missing boundaries for segmentation
"Chilling…Reads like a West Coast version of All the President’s Men." —The New York Times Book Review
The full inside story of the breathtaking rise and shocking collapse of Theranos, the multibillion-dollar biotech startup, by the prize-winning journalist who first broke the story and pursued it to the end, despite pressure from its charismatic CEO and threats by her lawyers.
In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose startup "unicorn" promised to revolutionize the medical industry with a machine that would make blood testing significantly faster and easier. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.
A riveting story of the biggest corporate fraud since Enron, a tale of ambition and hubris set amid the bold promises of Silicon Valley.
There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject.
This book, ‘Biochemistry’ is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.).
This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.
New to This Edition
The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects.
It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions.
It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry.
It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall.
It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc.
It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc.
It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.
A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging.
Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach.
In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
Each chapter ends with clinical cases and the related questions, which evokes yet another method of active learning rather than didactic methods of imparting knowledge.
Key points have been highlighted and boxed at the end of each topic for quick revision of the core concepts.
This book comes with a free companion website which contains self-assessment exercises, detailed case discussions related to the clinical cases given inside the book, glossary and various other features for enhanced learning.
As a result of our fitness tech addiction, we've lost awareness of what we're doing, how we're feeling, and what's going on around us. This is bad enough in the gym, but when we get outside, the constant checking of a tiny screen truly wreaks havoc, downgrading what should be a rich experience into yet another task we need to complete to meet our daily goals. And if we fall short, we feel inadequate. There’s also the issue of data inaccuracy, with many device makers now admitting that their gadgets provide only estimates. So why do we continue to obsess over data and treat it as gospel truth?
It's time to stop, take a breath, and hit the reset button in a big way. Unplugged provides a blueprint for using technology to meet your health and performance goals in a much smarter way, while reconnecting to your instincts and the natural world. In addition to sharing the performance expertise of Brian Mackenzie and the scientific insight of Dr. Andy Galpin, Unplugged features exclusive stories and advice from elite athletes and world-renowned experts like Laird Hamilton, Tim Ferriss, Kai Lenny, Kelly Starrett, Steven Kotler, Erin Cafaro, Lenny Wiersma, Dr. Frank Merritt, and Brandon Rager.
Reading Unplugged will enable you to:
• Understand both the value and the limitations of technology in athletic performance, fitness, health, and lifestyle situations
• Know how and when to utilize physical activity technologies in your everyday life—and when not to
• Avoid the common mistakes that most people make with wearables and tracking apps
• Understand which technologies and tests are most effective and which are a waste of money
• End your addiction to fitness technology and start utilizing it as a tool for cueing, learning, and sensing instead of as a taskmaster that stresses you out
• Improve self-awareness and increase self-reliance
• Re-engage with nature by spending less time indoors and more time outside
• Rediscover the value of coaches' expertise, curation, and intuition, which technology can't replace
• Take back control of your health, fitness, and performance with the Unplugged training protocol.
A Doody's Core Title for 2017!
THE BEST REVIEW FOR THE USMLE!
The Thirtieth Edition of Harper’s Illustrated Biochemistry combines outstanding full-colorillustrations with authoritative integrated coverage of biochemical disease and clinical information. Using brevity and numerous medically relevant examples, Harper's presents a clear, succinct review of the fundamentals of biochemistry that every student must understand in order to succeed in medical school.
All fifty-eight chapters emphasize the medical relevance of biochemistryFull-color presentation includes more than 600 illustrations Each chapter includes a section on BiomedicalImportance and a summary of the topics covered Review questions follow each of the eleven sections Case studies in every chapter emphasize the clinical relevance to biochemistry NEW coverage of toxic naturally-occurring amino acids; extraterrestrial biomolecules; computer-aided drug design; the role of complement cascade in bacterial and viral infection; secreted mediators of cell-cell signaling between leukocytes; the role of mast cells, basophils, andeosinophils; and the hazard of antioxidants that down-regulate radical signaling for apoptosis and increase risk of cancer
Applauded by medical students for its current and engaging style, Harper's Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic.
This Handbook is intended to serve as the basic reference point on image and video processing, in the field, in the research laboratory, and in the classroom. Each chapter has been written by carefully selected, distinguished experts specializing in that topic and carefully reviewed by the Editor, Al Bovik, ensuring that the greatest depth of understanding be communicated to the reader. Coverage includes introductory, intermediate and advanced topics and as such, this book serves equally well as classroom textbook as reference resource.
• Provides practicing engineers and students with a highly accessible resource for learning and using image/video processing theory and algorithms
• Includes a new chapter on image processing education, which should prove invaluable for those developing or modifying their curricula
• Covers the various image and video processing standards that exist and are emerging, driving today’s explosive industry
• Offers an understanding of what images are, how they are modeled, and gives an introduction to how they are perceived
• Introduces the necessary, practical background to allow engineering students to acquire and process their own digital image or video data
• Culminates with a diverse set of applications chapters, covered in sufficient depth to serve as extensible models to the reader’s own potential applications
About the Editor...
Al Bovik is the Cullen Trust for Higher Education Endowed Professor at The University of Texas at Austin, where he is the Director of the Laboratory for Image and Video Engineering (LIVE). He has published over 400 technical articles in the general area of image and video processing and holds two U.S. patents. Dr. Bovik was Distinguished Lecturer of the IEEE Signal Processing Society (2000), received the IEEE Signal Processing Society Meritorious Service Award (1998), the IEEE Third Millennium Medal (2000), and twice was a two-time Honorable Mention winner of the international Pattern Recognition Society Award. He is a Fellow of the IEEE, was Editor-in-Chief, of the IEEE Transactions on Image Processing (1996-2002), has served on and continues to serve on many other professional boards and panels, and was the Founding General Chairman of the IEEE International Conference on Image Processing which was held in Austin, Texas in 1994.
* No other resource for image and video processing contains the same breadth of up-to-date coverage
* Each chapter written by one or several of the top experts working in that area
* Includes all essential mathematics, techniques, and algorithms for every type of image and video processing used by electrical engineers, computer scientists, internet developers, bioengineers, and scientists in various,
Biomaterials: A Basic Introduction is a definitive resource for students entering biomedical or bioengineering disciplines. This text offers a detailed exploration of engineering and materials science, and examines the boundary and relationship between the two. Based on the author’s course lecture notes and many years of research, it presents students with the knowledge needed to select and design biomaterials used in medical devices. Placing special emphasis on metallic, ceramic, polymeric, and composite biomaterials, it explains the difference between materials science and materials engineering, introduces basic concepts and principles, and analyzes the critically important properties of biomaterials.
Explains Complex Theories Using Aspects of Daily Life
This text provides an appropriate balance between depth and broadness of coverage, and offers an understanding of the most important concepts and principles to students from a wide academic spectrum. It delivers the science of biomaterials in laymen terms, from a material standpoint, as well as a clinical applications point of view. It equips students majoring in materials science/engineering with knowledge on the fundamentals of how biomaterials behave at a biological level, and provides students majoring in medicine with information that is generally unavailable in traditional medical courses. The authors incorporate learning objectives at the beginning of each chapter, as well as chapter highlights, problems, and exercises at the end of each chapter. In addition, they present objectives, suggested activities, and reference material for further reading.Contains an overview of medical science vis-à-vis materials science, describes anatomy, histology, and cell biology Highlights health issues and diseases where biomaterials can easily find medical applications Presents knowledge of the relationship between the biomaterials and the living body Evaluates medical devices and looks into their respective regulations
Biomaterials: A Basic Introduction contains an overview of basic biomaterials and concepts, and is written for upper-division students in the US/Canada, and second-level students in universities worldwide.
A refresher for more experienced readers, the first part of the book presents an introduction to Python, Python modules, reading and writing images using Python, and an introduction to images. The second part discusses the basics of image processing, including pre/post processing using filters, segmentation, morphological operations, and measurements. The last part describes image acquisition using various modalities, such as x-ray, CT, MRI, light microscopy, and electron microscopy. These modalities encompass most of the common image acquisition methods currently used by researchers in academia and industry.
Deep learning has shown its power in several application areas of Artificial Intelligence, especially in Computer Vision. Computer Vision is the science of understanding and manipulating images, and finds enormous applications in the areas of robotics, automation, and so on. This book will also show you, with practical examples, how to develop Computer Vision applications by leveraging the power of deep learning.
In this book, you will learn different techniques related to object classification, object detection, image segmentation, captioning, image generation, face analysis, and more. You will also explore their applications using popular Python libraries such as TensorFlow and Keras. This book will help you master state-of-the-art, deep learning algorithms and their implementation.What you will learnSet up an environment for deep learning with Python, TensorFlow, and KerasDefine and train a model for image and video classificationUse features from a pre-trained Convolutional Neural Network model for image retrievalUnderstand and implement object detection using the real-world Pedestrian Detection scenarioLearn about various problems in image captioning and how to overcome them by training images and text togetherImplement similarity matching and train a model for face recognitionUnderstand the concept of generative models and use them for image generationDeploy your deep learning models and optimize them for high performanceWho this book is for
This book is targeted at data scientists and Computer Vision practitioners who wish to apply the concepts of Deep Learning to overcome any problem related to Computer Vision. A basic knowledge of programming in Python—and some understanding of machine learning concepts—is required to get the best out of this book.
The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression.
The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.
Computer Vision: Algorithms and Applications explores the variety of techniques commonly used to analyze and interpret images. It also describes challenging real-world applications where vision is being successfully used, both for specialized applications such as medical imaging, and for fun, consumer-level tasks such as image editing and stitching, which students can apply to their own personal photos and videos.
More than just a source of “recipes,” this exceptionally authoritative and comprehensive textbook/reference also takes a scientific approach to basic vision problems, formulating physical models of the imaging process before inverting them to produce descriptions of a scene. These problems are also analyzed using statistical models and solved using rigorous engineering techniques
Topics and features:Structured to support active curricula and project-oriented courses, with tips in the Introduction for using the book in a variety of customized courses Presents exercises at the end of each chapter with a heavy emphasis on testing algorithms and containing numerous suggestions for small mid-term projects Provides additional material and more detailed mathematical topics in the Appendices, which cover linear algebra, numerical techniques, and Bayesian estimation theory Suggests additional reading at the end of each chapter, including the latest research in each sub-field, in addition to a full Bibliography at the end of the book Supplies supplementary course material for students at the associated website, http://szeliski.org/Book/
Suitable for an upper-level undergraduate or graduate-level course in computer science or engineering, this textbook focuses on basic techniques that work under real-world conditions and encourages students to push their creative boundaries. Its design and exposition also make it eminently suitable as a unique reference to the fundamental techniques and current research literature in computer vision.
Uses a convenient format arranged by body system Contains high-quality images demonstrating the key features of basic anatomy Supplies both conventional imaging and cross-sectional CT and MRI anatomy to aid preparation for the FRCA 2A modules Presents guidelines on how to interpret images Includes case studies in each chapter to illustrate the application of anatomy Discusses commonly encountered pitfalls Matches the current curriculum of the FRCA Part 1 and Part 2A exams
The essential revision book for doctors training in radiology and preparing for the First FRCA exam, Practical Radiological Anatomy is also of great value to advanced radiology practitioners, nurse practitioners, emergency medicine doctors, and radiographers.
Avoiding the hype of popular science and the pessimism of most social science, Nikolas Rose analyzes contemporary molecular biopolitics, examining developments in genomics, neuroscience, pharmacology, and psychopharmacology and the ways they have affected racial politics, crime control, and psychiatry. Rose analyzes the transformation of biomedicine from the practice of healing to the government of life; the new emphasis on treating disease susceptibilities rather than disease; the shift in our understanding of the patient; the emergence of new forms of medical activism; the rise of biocapital; and the mutations in biopower. He concludes that these developments have profound consequences for who we think we are, and who we want to be.
Full-color illustrations and tablesthroughout help students master challenging concepts more easily.
Online case studiesserve as a self-assessment and review tool before exams.
Online access includes nearly 150 USMLE-style questions in addition to the questions that are in the book.
Glossary of technical terms.Clinical Boxes and Clinical Content demonstrate the integration of basic sciences and clinical applications, helping readers make connections between the two. New clinical examples have been added throughout the text.
Hybrid PET/CT and SPECT/CT represent new technologies that were introduced recently in clinical medicine and are evolving rapidly with several improvements in instrumentation, imaging procedures as well as in clinical trials that support the expanded role of these technologies in clinical practice. As such, an updated 4th edition of the Atlas is critical in order for the clinicians remain current with the imaging field and maintain their skills. Imaging protocols with these technologies have to be updated and/or expanded in order to acquire high quality images at a reduced radiation burden to the patient while advancing the application of these techniques for more advanced disease detection. Accordingly, beyond significantly updating the chapters from the 3rd edition, 2 new chapters will be introduced in the 4th edition, which reflects the expanded clinical applications of the technologies in the past 3 years. The new chapters are as follows: "Hybrid SPECT/CT and PET/CT Imaging" and a dedicated chapter on "Radiation Safety and Exposure: Clinical Decision-Making and the Risk-Benefit Ratio". Chapter 7 from the 3rd edition will be deleted.
The updated Atlas will serve as a reference source for all cardiologists, radiologists, and nuclear medicine physicians interested in the most up-to-date approaches to noninvasive diagnostic cardiovascular nuclear imaging techniques for the evaluation of patients with known or suspected coronary artery disease as well as non-coronary heart disease. It will also serve as a ready reference textbook for medical students and residents interested in the practice of cardiovascular medicine.
Used by thousands of medical students each year to succeed on USMLE Step 1, Kaplan's official lecture notes are packed with full-color diagrams and clear review.
The Best Review
Organized in outline format with high-yield summary boxes for efficient study.Clinical correlations and bridges between disciplines highlighted throughout.Full-color diagrams and charts for better comprehension and retention.Updated annually by Kaplan's all-star expert faculty
Looking for more prep? Our USMLE Step 1 Lecture Notes 2018: 7-Book Set has this book, plus the rest of the 7-book series.
The book is a "constructive dialogue" between contributors selected from a multidisciplinary group of Muslim and non-Muslim scholars from different Islamic countries. The 11 chapters illuminate the diversity and complexity of the issues discussed in Islamic bioethics and pave the way to a better understanding of Islamic bioethics and dialogue in the global bioethics community. The chapters take both theoretical and practical approaches to the topic, and each covers an emerging issue in Islamic bioethics.
This book will be useful for academics and professional institutions in both Islamic and non-Islamic countries, and will be instrumental in providing researchers, scholars, students, policymakers and medical professionals with access to the latest issues and debates related to Islamic bioethics.
Contributors include: Tariq Ramadan, Abdallah Daar, Ali Albar, Mohsin Ebrahim, Baharouddin Azizan Alastair Campbel, Bagher Larijani, Carol Taylor, Gamal Serour, James Rusthoven, Ilhan Ilkilic, Ingrid Mattson, Hassan Chamsi-Pasha, Jonathan Crane, Hakan Ertin, Mehunisha Suleman.
Contents: Islamic Ethics: Sources, Methodology and Application (T Ramadan)Islamic Bioethics: Infrastructure and Capacity Building (A Bagheri)What Islamic Bioethics Can Offer to Global Bioethics (A Bagheri et al.)Gender and Sexuality in Islamic Bioethics (I Mattson)Physician-Patient Relationship in Islamic Context (M Al Bar & H Chamsi-Pasha)Islamic Perspective on Brain Death and Organ Transplantation (M Ebrahim)The Stem Cell Debate in Islamic Bioethics (H Ertin & I Ilkilic)Environmental Ethics in Islam (A Baharuddin & M N Musa)Animal Rights in Islam (B Larijani et al.)Biomedical Research Ethics in the Islamic Context: Reflections on and Challenges for Islamic Bioethics (M Suleman)Challenges in Islamic Bioethics (K Alali et al.)
Readership: Healthcare professionals, health policy makers, physicians and nurses, lawyers academics, researchers, graduate students and lay public.
Keywords: Islamic Bioethics;Bioethics;Biomedical Ethics;Medical Ethics;IslamReview: Key Features: Provides a platform for a better understanding of bioethical issues in Islamic context and how an ethical dilemma is dealt with and how decisions are made in Islamic bioethics from a multidisciplinary group of scholarsBioethical topics presented in this volume are the most critical issues in Islamic bioethics as well as global bioethicsEach chapter presents an update of a bioethical topic and/or challenges in Islamic bioethics from an authoritative bioethics/religious scholarIn an innovative approach this volume presents a constructive dialogue between prominent Muslim and Non-Muslim scholars on Islamic bioethics
Helping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabrication, microfluidics, tissue engineering, cell-based and noncell-based devices, and implantable systems. It focuses on high-impact, creative work encompassing all the scales of life—from biomolecules to cells, tissues, and organisms.
Brilliant color presentation
Avoiding the overwhelming details found in many engineering and physics texts, this groundbreaking book—in color throughout—includes only the most essential formulas as well as many noncalculation-based exercises. Important terms are highlighted in bold and defined in a glossary. The text contains more than 400 color figures, most of which are from the original researchers.
Coverage of both historical perspectives and the latest developments
Developed from the author’s long-running course, this classroom-tested text gives readers a vivid picture of how the field has grown by presenting historical perspectives and a timeline of seminal discoveries. It also describes numerous state-of-the-art biomedical applications that benefit from "going small," including devices that record the electrical activity of brain cells, measure the diffusion of molecules in microfluidic channels, and allow for high-throughput studies of gene expression.
Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections
· Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body.
· Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing.
· Part three presents both in vitro and in vivo approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an in vivo model is used to assess molecular transport in brain tissue surrounding the implant.
· The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair.
This seminal work provides researchers with an up-to-date account of the progress in the field that they can build upon to bring us closer to realizing the full value of neural implants in combating otherwise intractable human health problems.
Thus, the Synthetic Biology Handbook provides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.
Part I deals with the principles, mode of operation, and uses of various biomedical instruments and devices, including transducers, electrocardiograph, implantable electrical devices, biotelemetry, patient monitoring systems, hearing aids, and implantable insulin delivery systems. Parts II and III describe the basic principle of medical imaging devices and the application of computers in medicine, particularly in the fields of data management, critical care, clinical laboratory, radiology, artificial intelligence, and research. Part IV focuses on the application of biomaterials and biomechanics in orthopedic and accident investigation, while Part V considers the major functions of clinical engineering. Part VI provides the principles and application of mathematical models in physiological systems analysis.
This book is valuable as a general reference for courses in a biomedical engineering curriculum.
Concise Computer Vision provides an accessible general introduction to the essential topics in computer vision, highlighting the role of important algorithms and mathematical concepts. Classroom-tested programming exercises and review questions are also supplied at the end of each chapter.Topics and features: provides an introduction to the basic notation and mathematical concepts for describing an image, and the key concepts for mapping an image into an image; explains the topologic and geometric basics for analysing image regions and distributions of image values, and discusses identifying patterns in an image; introduces optic flow for representing dense motion, and such topics in sparse motion analysis as keypoint detection and descriptor definition, and feature tracking using the Kalman filter; describes special approaches for image binarization and segmentation of still images or video frames; examines the three basic components of a computer vision system, namely camera geometry and photometry, coordinate systems, and camera calibration; reviews different techniques for vision-based 3D shape reconstruction, including the use of structured lighting, stereo vision, and shading-based shape understanding; includes a discussion of stereo matchers, and the phase-congruency model for image features; presents an introduction into classification and learning, with a detailed description of basic AdaBoost and the use of random forests.
This concise and easy to read textbook/reference is ideal for an introductory course at third- or fourth-year level in an undergraduate computer science or engineering programme.
The first 20 chapters are medical device technology chapters; the remaining eight chapters focus on medical device laboratory experiments. Each medical device chapter begins with an exposition of appropriate physiology, mathematical modeling or biocompatibility issues, and clinical need. A device system description and system diagram provide details on technology function and administration of diagnosis and/or therapy. The systems approach lets students quickly identify the relationships between devices.
Device key features are based on five applicable consensus standard requirements from organizations such as ISO and the Association for the Advancement of Medical Instrumentation (AAMI).The medical devices discussed are Nobel Prize or Lasker Clinical Prize winners, vital signs devices, and devices in high industry growth areasThree significant Food and Drug Administration (FDA) recall case studies which have impacted FDA medical device regulation are included in appropriate device chaptersExercises at the end of each chapter include traditional homework problems, analysis exercises, and four questions from assigned primary literatureEight laboratory experiments are detailed that provide hands-on reinforcement of device concepts
Written by a team of highly respected professors, the book can be used in a one-semester, intermediate-level course in computer science. It takes a practical problem-solving approach, avoiding detailed proofs and analysis. Suitable for readers without a deep academic background in mathematics, the text explains how to solve non-trivial geometric problems. It quickly gets readers up to speed on a variety of tools employed in visual computing and applied geometry.
The text begins by providing important background information on radiation effects, their underlying mechanisms, and the use of Monte Carlo techniques to simulate radiation transport and the effects of radiation on electronics. The book then:Explains the effects of radiation on digital commercial devices, including microprocessors and volatile and nonvolatile memories—static random-access memories (SRAMs), dynamic random-access memories (DRAMs), and Flash memories Examines issues like soft errors, total dose, and displacement damage, together with hardening-by-design solutions for digital circuits, field-programmable gate arrays (FPGAs), and mixed-analog circuits Explores the effects of radiation on fiber optics and imager devices such as complementary metal-oxide-semiconductor (CMOS) sensors and charge-coupled devices (CCDs)
Featuring real-world examples, case studies, extensive references, and contributions from leading experts in industry and academia, Ionizing Radiation Effects in Electronics: From Memories to Imagers is suitable both for newcomers who want to become familiar with radiation effects and for radiation experts who are looking for more advanced material or to make effective use of beam time.
Because the number of Centers for Pediatric Radiology is small, students as well as pediatricians and general radiologists lack training in pediatric radiology and are often not sufficiently aware of these differences.
Active radiation protection and avoidance of unnecessary high contrast media doses are number one priority in diagnosing and treating children and can be achieved through: Avoidance of X-rays and CT scans. Substitution with non-ionizing radiation such as ultrasonography and MRI where possible while ensuring diagnostic reliability; Reduction of the radiation dose and number of views. This can be realized by following the ALARA principle: “as low as reasonably achievable”; Weight and indication tailored contrast media dosing.
This CME accredited Manual provides a comprehensive overview on the field of pediatric radiology and suggests imaging strategies for the most common clinical indications in children and adolescents.
In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?
Tomosynthesis produces quasi-three-dimensional images that can significantly enhance the visualization of important diagnostic features. This book highlights the flexibility of tomosynthesis systems for new clinical applications, and provides a detailed discussion of the tomosynthesis acquisition process and the impact of physical factors. It explores such topics as acquisition parameters, system components, modeling, image reconstruction algorithms, and system evaluation.Provides in-depth coverage of system design considerations, as well as image reconstruction strategies Describes the current state of clinical applications of tomosynthesis, including imaging of the breast and chest, as well as its use in radiotherapy Illustrates the merits of tomosynthesis imaging and its potential clinical applications in imaging of the breast and chest, as well as for radiation therapy
Divided into five sections, this text delves into the history and development of tomosynthesis. It introduces tomosynthesis imaging, discusses imaging system design considerations, and reviews image reconstruction algorithms that have been developed for tomosynthesis. It also describes system evaluation methodologies, emphasizes current clinical applications, and examines the future direction for tomosynthesis.
Never before have two revolutions with so much potential to save and prolong human life occurred simultaneously. The converging, synergistic power of the biochemical and digital revolutions now allows us to read every letter of life's code, create precisely targeted drugs to control it, and tailor their use to individual patients. Cancer, diabetes, Alzheimer's and countless other killers can be vanquished—if we make full use of the tools of modern drug design and allow doctors the use of modern data gathering and analytical tools when prescribing drugs to their patients.
But Washington stands in the way, clinging to outdated drug-approval protocols developed decades ago during medicine's long battle with the infectious epidemics of the past. Peter Huber, an expert in science, technology, and public policy, demonstrates why Washington's one-size-fits-all drug policies can't deal with diseases rooted in the complex molecular diversity of human bodies. Washington is ill-equipped to handle the torrents of data that now propel the advance of molecular medicine and is reluctant to embrace the statistical methods of the digital age that can. Obsolete economic policies, often rationalized as cost-saving measures, stifle innovation and suppress investment in the medicine that can provide the best cures at the lowest cost.
In the 1980s, an AIDS diagnosis was a death sentence, until the FDA loosened its throttling grip and began streamlining and accelerating approval of life-saving drugs. The Cure in the Code shows patients, doctors, investors, and policy makers what we must now do to capture the full life-saving and cost-saving potential of the revolution in molecular medicine. America has to choose. At stake for America is the power to lead the world in mastering the most free, fecund, competitive, dynamic, and intelligent natural resource on the planet—the molecular code that spawns human life and controls our health.
The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field.Enables practicing engineers, students and clinical professionals to understand the essential physics and signal processing techniques behind modern imaging systems as well as introducing the latest developments that will shape medical ultrasound in the futureSuitable for both newcomers and experienced readers, the practical, progressively organized applied approach is supported by hands-on MATLAB® code and worked examples that enable readers to understand the principles underlying diagnostic and therapeutic ultrasoundCovers the new important developments in the use of medical ultrasound: elastography and high-intensity therapeutic ultrasound. Many new developments are comprehensively reviewed and explained, including aberration correction, acoustic measurements, acoustic radiation force imaging, alternate imaging architectures, bioeffects: diagnostic to therapeutic, Fourier transform imaging, multimode imaging, plane wave compounding, research platforms, synthetic aperture, vector Doppler, transient shear wave elastography, ultrafast imaging and Doppler, functional ultrasound and viscoelastic models