As a well-established scientific fact, biological evolution still provokes heated debates all over the world about its compatibility with religious beliefs. Moreover, the Darwinian theory, although remaining the general framework of life sciences, is in itself undergoing a sort of evolution by virtue of recent advancements in different biological disciplines, which lead to better assess the ideas that Darwin introduced more than 150 years ago. Finally, both the scientific fact of evolution and the Darwinian theory are concerns of philosophy and theology in relation to difficult issues such as the teleology ascribable to the realm of life, the meaning and relevance of ontological emergence, the mechanist and reductionist view of living beings, the level of complexity peculiar to biological systems, the relationships between evolution and Creation, the presence of contingency in nature, the ontological discontinuity between animals and the human being, and so on. The Conference held at the Pontifical Gregorian University represented a multidisciplinary attempt at dealing with such a cluster of intellectual problems, and this volume of proceedings testifies not only the event in its uniqueness but also the efforts made in order to establish a true dialogue beyond any kind of cheap agreement or ideological closure. The volume gathers the contributions provided by 37 prominent scholars - scientists, philosophers and theologians - coming from major academic institutions like the University of Cambridge, the University of Oxford, the Pontifical Academy of Sciences, the Stanford University, the College de France, the University of California, the University of Arizona, the Institute Catholique de Toulouse, the Center for Theology and Natural Sciences, and the University of Notre Dame that also participated to the organization of the Conference. Even if a lot of work is still to be done, this volume shows that important steps have been made towards a critical view of biological evolution, in which an appropriate philosophical mediation allows scientific knowledge and theological reflection to profitably interact. This seems crucial for establishing a culture that is both updated and an appropriate context for the human development of future generations.