In color throughout, the book takes readers through the history of important discoveries to the most current advances. It introduces the fundamentals of the fluorescence phenomenon and gives detailed examples of fluorescence applications in the molecular life sciences, including biochemistry, biophysics, clinical chemistry and diagnostics, pharmaceutical science, and cell and molecular biology. The author presents the basic theories underlying the applications and offers in-depth information on practical aspects.
Along with a list of references in each chapter, the text incorporates more than 250 figures that clearly illustrate the concepts and gives the chemical structures of the most widely used fluorescent molecules. In addition, the appendix provides a "Rogue’s Gallery" of the most common errors and pitfalls to avoid.
There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject.
This book, ‘Biochemistry’ is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.).
This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.
New to This Edition
The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects.
It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions.
It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry.
It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall.
It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc.
It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc.
It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.
the drama of the front lines.”
-Richard Danzig, former secretary of the navy
The first major bioterror event in the United States-the anthrax attacks in October 2001-was a clarion call for scientists who work with “hot” agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.
Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.
Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.
Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.
Imaging Informatics Professionals (IIPs) have come to play an indispensable role in modern medicine, and the scope of this profession has grown far beyond the boundaries of the PACS. A successful IIP must not only understand the PACS itself, but also have knowledge of clinical workflow, a base in several medical specialties, and a solid IT capability regarding software interactions and networking. With the introduction of a certification test for the IIP position, a single source was needed to explain the fundamentals of imaging informatics and to demonstrate how those fundamentals are applied in everyday practice. Practical Imaging Informatics describes the foundations of information technology and clinical image management, details typical daily operations, and discusses rarer complications and issues.
Each chapter ends with clinical cases and the related questions, which evokes yet another method of active learning rather than didactic methods of imparting knowledge.
Key points have been highlighted and boxed at the end of each topic for quick revision of the core concepts.
This book comes with a free companion website which contains self-assessment exercises, detailed case discussions related to the clinical cases given inside the book, glossary and various other features for enhanced learning.
THE BEST REVIEW FOR THE USMLE!
The Thirtieth Edition of Harper’s Illustrated Biochemistry combines outstanding full-color illustrations with authoritative integrated coverage of biochemical disease and clinical information. Using brevity and numerous medically relevant examples, Harper's presents a clear, succinct review of the fundamentals of biochemistry that every student must understand in order to succeed in medical school.
All fifty-eight chapters emphasize the medical relevance of biochemistryFull-color presentation includes more than 600 illustrations Each chapter includes a section on Biomedical Importance and a summary of the topics covered Review questions follow each of the eleven sections Case studies in every chapter emphasize the clinical relevance to biochemistry NEW coverage of toxic naturally-occurring amino acids; extraterrestrial biomolecules; computer-aided drug design; the role of complement cascade in bacterial and viral infection; secreted mediators of cell-cell signaling between leukocytes; the role of mast cells, basophils, and eosinophils; and the hazard of antioxidants that down-regulate radical signaling for apoptosis and increase risk of cancer
Applauded by medical students for its current and engaging style, Harper's Illustrated Biochemistry is an essential for USMLE review and the single best reference for learning the clinical relevance of any biochemistry topic.
This important guide/reference presents a comprehensive overview of medical image analysis. Highly practical in its approach, the text is uniquely structured by potential applications, supported by exercises throughout. Each of the key concepts are introduced in a concise manner, allowing the reader to understand the interdependencies between them before exploring the deeper details and derivations.
Topics and features: presents learning objectives, exercises and concluding remarks in each chapter, in addition to a glossary of abbreviations; describes a range of common imaging techniques, reconstruction techniques and image artefacts; discusses the archival and transfer of images, including the HL7 and DICOM standards; presents a selection of techniques for the enhancement of contrast and edges, for noise reduction and for edge-preserving smoothing; examines various feature detection and segmentation techniques, together with methods for computing a registration or normalisation transformation; explores object detection, as well as classification based on segment attributes such as shape and appearance; reviews the validation of an analysis method; includes appendices on Markov random field optimization, variational calculus and principal component analysis.
This easy-to-follow, classroom-tested textbook is ideal for undergraduate and graduate courses on medical image analysis and related subjects – with possible course outlines suggested in the Preface. The work can also be used as a self-study guide for professionals in medical imaging technology, and for computer scientists and engineers wishing to specialise in medical applications.
Detailed calculation steps, useful comments, and mathematical hints enhance solved problems throughout...
Encouraging the use of the Ratio Method, the author draws attention to its applicability to a wide variety of biochemistry problems with logical consistency and intuitive ease. This entirely revised and updated second edition introduces three new chapters with coverage of laboratory-oriented calculations and data presentation, calculations relating to the emerging techniques in DNA and molecular biology, and applying the Ratio Method to pharmaceutical calculations.
New edition adds questions and extra tips in every chapter to help students perform biochemical calculations on their own!
By strengthening their understanding of mathematical logic and problem solving skills, Fundamentals of Biochemical Calculations, Second Edition enables students and biochemists to explore a wider range of real-world applications with the ability to tackle increasingly complex problems in biochemistry and related fields.
This technique-specific book is primarily of benefit to those in training in general radiology and more specifically for Residents and Fellows who are training in interventional radiology and who may be taking subspeciality certificate examinations in interventional radiology. In addition, this book will be of help to most practicing interventional radiologists, be they be in academic or private practice. This is the kind of book that can be left in the interventional lab and will be of benefit to ancillary staff, such as technicians/radiographers or nurses who are specialising in the care of patients referred to interventional radiology.
This volume on neurointervention will enhance the series by expounding on the specific techniques required when working on conditions of the head, neck and spine.
- detailed information on sequence parameters for different magnets and vascular territories for the optimization of the MRA technique;
- a broad overview of the principal indications for which contrast-enhanced MR angiography is ideally suited;
- the typical MR imaging findings associated with various pathologies;
- the appropriateness of contrast-enhanced MRA as compared with other modalities, such as CTA and CEUS;
- the potential pitfalls and limitations of the technique in clinical routine.
The volume will prove invaluable to radiologists and clinicians wishing to expand, improve, or consolidate their routine approach to vascular MR imaging.
The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illustrated clinical case reports are then presented. Each case study includes a short clinical history, findings, and teaching points, followed by illustrations, legends, and comments.
The multimedia version of the book includes dynamic movies that allow the reader to browse through series of rotating 3D images (MIP or volume rendered), display blending between PET and MR, and dynamic visualization of 3D image volumes. The movies can be played either continuously or sequentially for better exploration of sets of images.
The editors of this state-of-the-art publication are key opinion leaders in the field of multimodality imaging. Professor Osman Ratib (Geneva) and Professor Markus Schwaiger (Munich) were the first in Europe to initiate the clinical adoption of PET/MR imaging. Professor Thomas Beyer (Zurich) is an internationally renowned pioneering physicist in the field of hybrid imaging. Individual clinical cases presented in this book are co-authored by leading international radiologists and nuclear physicians experts in the use of PET and MRI.
See What’s New in the Third Edition:
New chapters covering biological rhythms and insect symbioses Adds references from the last several years to bring each chapter up to date Provides new review and self-study questions that aid in distinguishing the most important information and concepts References to websites where illustrative materials have been provided by scientists and contains approximately 2,600 citations Twenty-four pages of color illustrations with new illustrations that emphasize genetic and molecular developments in insect biology Update of the rapidly developing area of postembryonic development of insects, especially the role of the juvenile hormone in insect development
While this edition provides new information and significant updates, it also maintains all the features that made previous editions so popular, such as citations that enable you to get to the primary literature easily and understand the thinking, experimentation, and techniques that have enabled the current understanding of the physiology of insects. And clear writing with technical terms explained in the text where they occur. With more than 250 illustrations to help explain physiological concepts and important anatomical details, the book remains the most easily accessible guide to key concepts in the field.
The editors have built Amylases—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about alpha-Amylases in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Amylases—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility.
The purpose of this volume is to help the decision-making process by comparing different solution properties describing their indications, mechanisms of action and side-effects according to physiologic body water distribution, electrolytic and acid-base balance, and to clarify which products available on the market represent the best choice in different circumstances. The book opens by discussing in detail the concepts central to a sound understanding of abnormalities in fluid and electrolyte homeostasis and the effect of intravenous fluid administration. In the second part of the monograph, these concepts are used to explain the advantages and disadvantages of solutions available on the market in different clinical settings. Body Fluid Management: From Physiology to Therapy will serve as an invaluable decision-making guide, including for those who are not experts in the subject.
Louann Brizendine, M.D. is a pioneering neuropsychiatrist who brings together the latest findings to show how the unique structure of the female brain determines how women think, what they value, how they communicate, and whom they’ll love. Brizendine reveals the neurological explanations behind why
• A woman remembers fights that a man insists never happened
• A teen girl is so obsessed with her looks and talking on the phone
• Thoughts about sex enter a woman’s brain once every couple of days but enter a man’s brain about once every minute
• A woman knows what people are feeling, while a man can’t spot an emotion unless somebody cries or threatens bodily harm
• A woman over 50 is more likely to initiate divorce than a man
Women will come away from this book knowing that they have a lean, mean communicating machine. Men will develop a serious case of brain envy.
From the Hardcover edition.
Written entirely by experts in their fields, Practical Pelvic Floor Ultrasonography: A Multicompartmental Approach to 2D/3D/4D Ultrasonography of Pelvic Floor is a comprehensive resource that will be of great value to urogynecologists, colorectal surgeons, obstetrician and gynecologists, female urologists, ultrasonographers, radiologists, physiotherapists, as well as fellows in urogynecology and colorectal surgery.
Edited by Mukesh G. Harisinghani, MD, with chapter contributions from staff members of the Department of Radiology at Massachusetts General Hospital.
The series comprises a number of titles, which cover procedures in angioplasty and stenting, transcatheter embolization and therapy, biopsy and drainage, ablation, pediatric interventional radiology and neurointerventional radiology.
Each book is laid out in bullet point format, so that the desired information can be located quickly and easily. Interventional radiologists at all stages, from trainees through to specialists, will find this book a valuable asset for their practice.
Interventional Radiology Techniques in Ablation is a practical and concise guide to contemporary techniques in image-guided tumor ablation. This handbook is intended to serve as a quick reference for physicians in interventional radiology training as well as a resource for IR technologists, nurses, nurse practitioners and physician assistants.
Erik Seedhouse is eminently qualified to describe the effects of large accelerations on the body. In addition to being the author of several previously published Springer Praxis books, he has developed astronaut-training protocols and is the training director for Astronauts for Hire (A4H). He is also the Canadian Forces’ High Risk Acceleration Training Officer.
Herbal remedies have been around for years and many people count on them every day. Some carry a strong belief that there is no need to rely on medications. Among the alternative medicine approaches, essential oils are used for a number of different conditions and offer a variety of benefits.
After a stress filled day, it would be nice to come home and just relax. Some have found that they can get fast relaxation by taking a warm bath using essential oils. A mix of the oils and the aromas can relax one so much that it puts the client to sleep.
Because essential oils are extracted from plant material, they often contain the nutritional essence of the plants themselves. In concentrated form, they can impart huge health benefits, when they are ingested into the body.
Essential Oils will guide you through the various uses and benefits of essential oils, highlighting how to use them to lose weight, relieve pain, maintain your skin, as well as strengthen your hair. The various uses of essential oils is nearly limitless. Come discover what many others have: that there is now a safer, more natural way to protect yourself and your family.
Because the number of Centers for Pediatric Radiology is small, students as well as pediatricians and general radiologists lack training in pediatric radiology and are often not sufficiently aware of these differences.
Active radiation protection and avoidance of unnecessary high contrast media doses are number one priority in diagnosing and treating children and can be achieved through: Avoidance of X-rays and CT scans. Substitution with non-ionizing radiation such as ultrasonography and MRI where possible while ensuring diagnostic reliability; Reduction of the radiation dose and number of views. This can be realized by following the ALARA principle: “as low as reasonably achievable”; Weight and indication tailored contrast media dosing.
This CME accredited Manual provides a comprehensive overview on the field of pediatric radiology and suggests imaging strategies for the most common clinical indications in children and adolescents.
The easy way to take the confusion out of organic chemistry
Organic chemistry has a long-standing reputation as a difficult course. Organic Chemistry I For Dummies takes a simple approach to the topic, allowing you to grasp concepts at your own pace.
This fun, easy-to-understand guide explains the basic principles of organic chemistry in simple terms, providing insight into the language of organic chemists, the major classes of compounds, and top trouble spots. You'll also get the nuts and bolts of tackling organic chemistry problems, from knowing where to start to spotting sneaky tricks that professors like to incorporate.Refreshed example equations New explanations and practical examples that reflect today's teaching methods Fully worked-out organic chemistry problems
Baffled by benzines? Confused by carboxylic acids? Here's the help you need—in plain English!
Why do you fall in love with one person rather than another? In this fascinating and informative book, Helen Fisher, one of the world's leading experts on romantic love, unlocks the hidden code of desire and attachment. Each of us, it turns out, primarily expresses one of four broad personality types—Explorer, Builder, Director, or Negotiator—and each of these types is governed by different chemical systems in the brain. Driven by this biology, we are attracted to partners who both mirror and complement our own personality type.
Until now the search for love has been blind, but Fisher pulls back the curtain and reveals how we unconsciously go about finding the right match. Drawing on her unique study of 40,000 men and women, she explores each personality type in detail and shows you how to identify your own type. Then she explains why some types match up well, whereas others are problematic. (Note to Explorers: be prepared for a wild ride when you hitch your star to a fellow Explorer!) Ultimately, Fisher's investigation into the complex nature of romance and attachment leads to astonishing new insights into the essence of dating, love, and marriage.
Based on entirely new research—including a detailed questionnaire completed by seven million people in thirty-three countries—Why Him? Why Her? will change your understanding of why you love him (or her) and help you use nature's chemistry to find and keep your life partner.