As progress in deciphering genotype-to-phenotype relationships in AD accelerated during the last two decades, it became apparent that the key challenge for understanding and ultimately treating AD was to focus not on what was killing neurons over the course of the disease but rather on what was interfering subtly and intermittently with episodic declarative memory well before widespread neurodegeneration had occurred . In other words, one wishes to understand the factors underlying early synaptic dysfunction in the hippocampus and then attempt to neutralize these as soon as feasible, perhaps even before a definitive diagnosis of AD can be made. This steady movement of the field toward ever-earlier stages of the disorder is exemplified by the recognition and intensive study of minimal cognitive impairment–amnestic type (MCI; . And yet patients who die with a diagnosis of MCI have been found to already have a histopathology essentially indistinguishable from classical AD . Therefore, even earlier phases of this continuum are likely to become recognized, and these might show milder histopathology and might have biochemically, but not yet microscopically, detectable Ab species that mediate synaptic dysfunction.
This volume serves as a record focused on bringing together investigators at the forefront of elucidating the structure and function of hippocampal synapses with investigators focused on understanding how early assemblies of Ab may compromise some of these synapses.
Debilitating brain disorders are on the rise-from children diagnosed with autism and ADHD to adults developing dementia at younger ages than ever before. But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.
In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.
A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline.
Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease.
In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene.
The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.
It was at this moment, Omalu studying slides of Webster’s brain tissue under a microscope, that the world of contact sports would never be the same: the discovery of Chronic Traumatic Encephalopathy. CTE can result in an array of devastating consequences including deterioration in attention, memory loss, social instability, depression, and even suicide. And Omalu’s discovery of CTE in the brain of an American football player has become the catalyst of a blazing controversy across all contact sports.
At the center of that controversy stands the unlikely Dr. Bennet Omalu, a Nigerian-born American citizen, a mild-mannered, gentle man of faith. It is fascinating that it would take someone on the outside of American culture to make this amazing discovery, and refuse to let it be kept hidden. Dr. Omalu began his life in strife, growing up in war-torn Nigeria. But his medical studies in forensic pathology proved to be a lifeline. It fed his natural curiosity and awakened within a deeper desire to always search for the truth. Who would have thought that such an unexpected character would play such a role in bringing to life this world-changing data?
In Truth Doesn’t Have a Side, discover the truth about CTE: Its causes and symptoms, how we might keep our children safe and guide professional athletes when CTE sets in. The problem of CTE is coming to light with each new story about an athlete’s concussion problem, and we are likely facing dramatic changes to professional sports. You’ll be inspired by Dr. Bennet Omalu a man driven by his love and concern for the welfare of all people, and his professional vow to speak the truth.
In The Migraine Miracle, a neurologist with a personal history of migraines offers readers the revolutionary dietary cure that has worked for him and continues to work for his patients: a diet low in wheat, sugar, and processed foods, and high in organic, protein-rich animal products. The book also explores the link between inflammation, diet, and migraines, and contains a 21-day meal plan to help readers change the way they eat. By following this easy meal plan, millions of sufferers will discover a life free from symptoms—once and for all.
The book includes comprehensive, research-based information that explains what the brain goes through during a migraine headache, the phases of the migraine, and how a diagnosis is made. It also explores the risks and benefits of migraine medication, natural remedies for migraines, dietary migraine triggers, and detailed, specific instructions for a migraine-free eating plan.
If you have tried migraine medicine but have not found real relief, it’s time to try something new. By changing the way you eat, and understanding what foods can trigger your migraine, you can start feeling better longer, without the threat of a migraine always looming over everything you do.
Praised for her excellence and compassion, the founder of the Women's Headache Center near Boston, and a migraine sufferer herself, Dr. Bernstein has helped hundreds of her patients get better. Now, with The Migraine Brain, the most comprehensive, up-to-the-minute book on migraines ever written, you will be able to do the same -- reduce the frequency and intensity of your migraines, learn how to prevent and curtail them and how to recover from them more quickly, and mitigate migraine's effects on every aspect of your life: in the workplace and at home and during sex and travel. Every migraine is different because everyone who gets a migraine has a distinctive "Migraine Brain" with its own sensitivities and triggers. That's why it's so important for you to develop a personalized wellness plan to radically reduce the number and severity of your migraines.
Dr. Bernstein also explains why migraines happen, why they are so often misdiagnosed, and why so few people get the right treatment for them. She reveals the latest research that shows that Migraine Brains share a hypersensitivity to stimuli -- the Migraine Brain can actually look different from others on a brain scan -- and is more likely to experience a cascade of neurological reactions that give rise to the common clusters of migraine symptoms. This breakthrough medical knowledge makes treatment and recovery possible with new migraine-specific drugs as well as with complementary treatments such as yoga, biofeedback, and an exercise regimen.
With the extraordinarily thorough recommendations of The Migraine Brain in your hands, you will be fully equipped with all the latest information you need to understand migraines and to help your family and co-workers understand that migraine isn't just a headache: it's a serious, yet treatable disease.
With a traumatic brain injury (TBI) occurring every 18.5 seconds in this country - concussions the most common - chances are you have been touched in some way by this experience. TBIs occur due to accidents and sports, and are also common in returning soldiers. The personal stories in this book, by TBI survivors and those who love and support them, will help and encourage you and your family on your road to recovery.
Neurosurgeons are renowned for their big egos and aggressive self-confidence, and Dr. Firlik confirms that timidity is indeed rare in the field. “They’re the kids who never lost at musical chairs,” she writes. A brain surgeon is not only a highly trained scientist and clinician but also a mechanic who of necessity develops an intimate, hands-on familiarity with the gray matter inside our skulls. It’s the balance between cutting-edge medical technology and manual dexterity, between instinct and expertise, that Firlik finds so appealing–and so difficult to master.
Firlik recounts how her background as a surgeon’s daughter with a strong stomach and a keen interest in the brain led her to this rarefied specialty, and she describes her challenging, atypical trek from medical student to fully qualified surgeon. Among Firlik’s more memorable cases: a young roofer who walked into the hospital with a three-inch-long barbed nail driven into his forehead, the result of an accident with his partner’s nail gun, and a sweet little seven-year-old boy whose untreated earache had become a raging, potentially fatal infection of the brain lining.
From OR theatrics to thorny ethical questions, from the surprisingly primitive tools in a neurosurgeon’s kit to glimpses of future techniques like the “brain lift,” Firlik cracks open medicine’s most prestigious and secretive specialty. Candid, smart, clear-eyed, and unfailingly engaging, Another Day in the Frontal Lobe is a mesmerizing behind-the-scenes glimpse into a world of incredible competition and incalculable rewards.
From the Hardcover edition.
Experts Acclaim for "Addiction--What's Really Going On?"
"Once I started reading Addiction--What's Really Going On? I couldnot put it down! You can tell the passion the author has as you read it.I can also tell how she learned about methadone and the patients as sheprogressed in her work."
--Roxanne Baker, CMA, President National Alliance of Methadone Advocates (NAMA)
"Addiction--What's Really Going On? is gritty and gripping as you enterthe lives of those who are like crabs trying to get out of a barrel. Hopecomes when you realize that there are people in this world committed tounselfish service who have unconditional love for others. Thank you Deborahand Barbara for showing us your humanity and for what we canaspire to."
--Anusha Amen-Ra, CNC, CEO, Sacred Space Healing and Retreat Centers International, Inc.
"Addiction--What's Really Going On? is a truthful look into the worldof Methadone Treatment with a mix of compassion and humor. It is agreat read for those in the recovery field and provides insight for thosewho do not understand the life of addiction and recovery."
--Lori Carter-Runyon, Executive Director Hilltop Recovery Services
"I recommend this book to audiences in any helping profession, people in recovery, the families of drug addicts, and the users themselves."
--Bill Urell, MA, CAAP-II, Addictions Therapist Author, "The Addiction Recovery Help Guide"
About the Author
Barbara Sinor, PhD is a Psychospiritual Therapist working with individuals dealing with addictions, childhood abuse/incest, PTSD, and adult children of alcoholics. Barbara utilizes a holistic methodology in her counseling encompassing forms of hypnotherapy, regression therapy, Gestalt, Jungian dreamwork, and other transpersonal techniques.Dr. Sinor holds a Doctorate in Psychology; an MA from John F. Kennedy University; and a BA from Pitzer College.
For more information, please visit www.DrSinor.com
From Loving Healing Press www.LovingHealing.com
Psychology: Psychopathology - Addiction
The chapters include more than 100 boxes describing clinical conditions, techniques, and other special topics. Each chapter went through a thorough review process, giving the book an evenness of tone. The chapters are authored by outstanding working scientists who are experts on the topics they cover.Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries30% new material including new chapters on dendritic development and spine morphogenesis, chemical senses, cerebellum, eye movements, circadian timing, sleep and dreaming, and consciousnessAccompanying website for students and instructorsAdditional text boxes describing key experiments, disorders, methods, and conceptsMore than 650 four-color illustrations, micrographs, and neuroimages Multiple model system coverage beyond rats, mice, and monkeysExtensively expanded index for easier referencing
Does this sound familiar to you?
That was 6 years ago when I first experienced the shocking sciatica pain. Horror could not begin to describe how I felt that day. For the next 12 weeks I went through hell and back. Through a series of non-surgical treatments, exercises, and stretches, I have been back pain free & have not needed to see a healthcare professional for sciatica since then. I continue to care for my back with stretching, walking and sometimes back strengthening exercises. Oh, and every now and then, I also treat my back to spinal decompression at the chiropractor’s office.
The single most important thing I learned through my ordeal with sciatica is that there is no way any doctor can tell every patient everything he or she needs to know and, unfortunately, most patients don’t know what questions to ask.
This is why I wrote "Sciatica No More." I am hoping that this book will help people learn about their conditions, learn of the many treatment options, learn to live within the limitations of their bodies and learn to live free from sciatica pain.
In this book, you will learn:
- What is sciatica & sciatic nerve pain
- Sciatica diagnostic processes, sciatica symptoms
- Common causes of sciatica
- Non-surgical treatment options
- Natural remedies for sciatica pain
- Exercises for sciatica relief
- Surgical treatment options
- Working with sciatica pain
- Travelling with sciatica pain
- Sleeping with sciatica pain
- Myths and facts about sciatica
- Learn to say sayonara sciatica
- And much more...
Although there is no known cure for Fibromyalgia, latest advances in medical science have gained a lot of knowledge about this unusual disease. There are now treatment options available. There are also natural remedies available to help with Fibromyalgia pain relief.
"Fibromyalgia STOP!" is packed with the latest cutting edge information on Fibromyalgia and it took over 1 year to research, gather the data and compile it into this new eBook.
Just imagine it is possible to start getting relief from Fibromyalgia pain in as little as 7 days!
Here's what you'll discover in "Fibromyalgia STOP!":
- How to better understand how Fibromyalgia affects your body...
- What are possible causes of Fibromyalgia...
- 3 little known, yet simple ways to use diet to help relief your pain...
- Newer medicine available to treat fibromyalgia...
- Secrets from experts that few people ever know about...
- 3 proven steps to using alternative therapies to get yourself on the road to free from pain...
- 2 simple keys (that are right in front of your eyes) to using home remedies to treat your symptoms...
- WARNING: 3 things you should never do when it comes to relieving Fibromyalgia pain...
- You'll discover in just a few short minutes how to make sure you what you are experiencing is actually Fibromyalgia...
- 6 time tested and proven strategies for using herbs to increase your sinus health...
- 7 everyday but often overlooked tips and tricks for using alternative medicine like acupuncture and acupressure to relief pain...
- and much more...
A star science journalist with Parkinson's reveals the inner workings of this perplexing disease
Seven million people worldwide suffer from Parkinson's, and doctors, researchers, and patients continue to hunt for a cure. In Brain Storms, the award-winning journalist Jon Palfreman tells their story, a story that became his own when he was diagnosed with the debilitating illness.
Palfreman chronicles how scientists have worked to crack the mystery of what was once called the shaking palsy, from the earliest clinical descriptions of tremors, gait freezing, and micrographia to the cutting edge of neuroscience, and charts the victories and setbacks of a massive international effort to best the disease. He takes us back to the late 1950s and the discovery of L-dopa. He delves into a number of other therapeutic approaches to this perplexing condition, from partial lobotomies and deep brain stimulation to neural grafting. And he shares inspiring stories of brave individuals living with Parkinson's, from a former professional ballet dancer who tricks her body to move freely again to a patient who cannot walk but astounds doctors when he is able to ride a bicycle with no trouble at all.
With the baby boom generation beginning to retire and the population steadily aging, the race is on to discover a means to stop or reverse neurodegenerative conditions like Parkinson's and Alzheimer's. Brain Storms is the long-overdue, riveting, and deeply personal story of that race, and a passionate, insightful, and urgent look into the lives of those affected.
When will there be a cure?
Dr. Howard Weiner has spent nearly three decades trying to find answers to the mysteries of multiple sclerosis, an utterly confounding and debilitating disease that afflicts almost half a million Americans. Curing MS is his moving, personal account of the long-term scientific quest to pinpoint the origins of the disease and to find a breakthrough treatment for its victims.
Dr. Weiner has been at the cutting edge of MS research and drug development, and he describes in clear and illuminating detail the science behind the symptoms and how new drugs may hold the key to "taming the monster." From the "Twenty-one Points" of MS--a concise breakdown of the knowns and unknowns of the disease--to stories from the frontlines of laboratories and hospitals, Curing MS offers a message of hope about new treatments and makes a powerful argument that a cure can--and will--be found.
From the Hardcover edition.
Brain Injury Medicine, 2nd Edition Features:The acknowledged gold standard reference-brings together knowledge, experience, and evidence-based medicineComprehensive and current-completely revised, updated, and expanded to include emerging topics and the latest clinical and research advances Multi-disciplinary focus-expert authorship from a wide range of specialties promotes a holistic team approach to a complex, many-faceted condition Covers the entire continuum of care from early diagnosis and assessment through acute management, rehabilitation, associated medical and quality of life issues, and functional outcomes
New to the Second Edition:Three new Associate Editors from related disciplines provide added expertise Five new sections: acute rehabilitative care, pediatric TBI, special senses, autonomic and other organ system problems, post-trauma pain disorders 25 new chapters running the gamut from health policy to biomechanics, to military TBI to pediatric issues and more Print + Digital Access: Purchase price includes enhanced e-book containing the complete and fully searchable text plus additional digital-only content
Now in an updated eighth edition, the Handbook of Neurosurgery has enjoyed legendary status on the bookshelf of every neurosurgery department for over a quarter of a century. Renowned for its scope and accessibility, the portable, single-volume guide is an invaluable resource for anyone involved in the care of patients with disorders of the central nervous system – neurosurgical residents, nurses, neurologists, and allied healthcare practitioners.
This classic handbook covers the full depth and breadth of the complex field of neurosurgery – including inherited and acquired neurological disorders, developmental anomalies, and more esoteric topics such as toxins that impact the central nervous system. The text also covers conditions treated primarily by neurologists that may come to the attention of a neurosurgical care provider such as Parkinsonism, multiple sclerosis, motor neuron diseases, and dementia. The latest information is provided on anatomy and physiology, differential diagnosis, and current principles of nonsurgical and surgical management covering the full age continuum – from pediatric to geriatric conditions.
Key Features:Expanded four-color graphics and illustrations Packed with more than 1,600 pages of practical information, including thousands of literature citations, handy cross-references, and a comprehensive index Fundamentals of neurocritical care, with a comprehensive overview of conditions – from SAH to head and spine trauma – and complications such as rebleeding, vasospasm, cerebral salt wasting, and brain death
Comprehensive and conveniently compact, this is a must-have daily reference, a perfect study companion for board exams, as well as ideal for maintenance of certification preparation. It is certain to be a treasured tome for legions of new neurosurgery residents and an essential tool for anyone working in the clinical neurosciences.
In 1988, Su Meck was twenty-two and married with two children when a ceiling fan fell and struck her on the head, erasing all her memories of her life. Although her body healed rapidly, her memories never returned. After just three weeks in the hospital, her physicians released Su and she returned home to take care of her two toddlers. What would you do if you lost your past?
Adrift in a world about which she understood almost nothing, Su became an adept mimic, gradually creating routines and rituals that sheltered her and her family from the near-daily threat of disaster—or so she thought. Though Su would eventually relearn to tie her shoes, cook a meal, read, and write, nearly twenty years would pass before a series of personally devastating events shattered the “normal” life she had worked so hard to build, and she realized that she would have to grow up all over again.
In her own indelible voice, Su offers a unique view from the inside of a terrible injury as she “recounts her grueling climb back to normalcy…in this heart-wrenching true story” (O, The Oprah Magazine). Piercing, heartbreaking, but finally uplifting, I Forgot to Remember is the story of a woman determined to live life on her own terms.
An immediate classic, this groundbreaking text is based on the premise that neurointensivists must be trained to handle not only the brain, but the entire body. The NeuroICU Book, Second Edition does not limit coverage to the brain and spine – it spans all organ insufficiencies and failures – along with neurologic illnesses.
Thoroughly updated to keep pace with all the advances in this emerging field, the Second Edition of The NeuroICU Book combines the latest clinical perspectives in critical care medicine, neurology, and neurosurgery. This practical, evidence-based text standardizes neurocritical care and takes you through the rationale for those standards. Filled with detailed case studies and enhanced by a question-and-answer format, the book not only builds competency in recognizing acute changes in neurological function, but also addresses all organ insufficiencies and failures, reflecting the real-life challenges in the modern neuro-ICU.
• Strong emphasis on clinical practicality
• Evidence-based approach leverages the scientific and controlled research that supports the key treatment methods outlined in the book
• Practical tools include algorithms, tables, illustrations, photographs, detailed references, and critical take home points
• Balanced coverage of neurologic and critical care and neurosurgery offers outstanding preparation for the neurocritical care board certification exam as well as an indispensable primer for daily clinical work
• Second Edition includes new chapters covering CNS infection, paroxysmal sympathetic hyperactivity, acute liver failure, encephalopathy and delirium, spine trauma, pediatric neurosurgery, and carotid endarterectomy and extracranial-intracranial bypass
Neurological Differential Diagnosis is a streamlinedhandbook of prioritized differential diagnosis, to be usedboth in clinical practice and for exam review.
By presenting differential diagnosis in order of frequency andimportance, this book provides a practical handbook for cliniciansin training, as well as a potential resource for quick boardreview. Whilst the book covers the most important syndromes anddisease entities, readers are referred to other texts for moreexhaustive differentials. By limiting differentials in this way -to the most likely and most serious diagnoses - the reader can moreeasily recall relevant disease processes when faced with aparticular clinical situation, whether it be a patient in theemergency room or a difficult question on the boardexamination.
The book specifically targets neurology residents and fellows,with overlap to neurosurgery and psychiatry. Internal medicinephysicians with an interest in neurological problems and medicalstudents looking for an edge in clinical neuroscience would alsobenefit from this text.
The content is primarily mid-level material, in a pedagogicformat.
In order to organize the students' thought processes concisetables and line drawing templates are included. The book isorganized into broad chapters by type of disorder and some overlapoccurs between particular chapters.
Fundamentals of neurovascular anatomy and basic angiographic techniques;
Interventional Techniques and endovascular methods, along with useful device information and tips and tricks for daily practice;
Specific Disease States, with essential clinical information about commonly encountered conditions.
New features in the 2nd Edition include:
Global Gems that illuminate aspects of the field outside the United States;
Angio-anatomic and angio-pathologic image correlates;
Newly released clinical study results influencing neurointerventional practice;
Information on emerging technologies in this rapidly advancing field.
The Handbook is a vital resource for all clinicians involved in neurointerventional practice, including radiologists, neurosurgeons, neurologists, cardiologists, and vascular surgeons.
Written by an expert in the field, this book provides a coherent and structured narrative appropriate for students in need of an introduction to the topic of reasoning as well as researchers seeking well-rounded foundational content. It is essential reading for neuroscientists, cognitive scientists, neuropsychologists and others interested in the neural mechanisms behind thinking, reasoning and higher cognition.Provides a comparative perspective considering animal cognition and its relevance to human reasoningIncludes developmental and lifespan considerations throughout the bookDiscusses technological development and its role in reasoning, both currently and in the futureConsiders perspectives from not only neuroscience, but cognitive psychology, philosophy, development, and animal behavior for a multidisciplinary treatmentContains highlight boxes featuring additional details on methods, historical descriptions and experimental tasks
Epilepsy Board Review contains over 360 questions with answers, detailed explanations, and references. The book is divided into four sections covering phenomenology of seizures and epileptic disorders, basic EEG, diagnostic evaluation of seizures and epilepsy, and treatment. Liberal use of image-based questions presenting EEG and neuroimaging findings build interpretive skills and foster improved understanding of applications and interventions. Questions are randomized and include both case-related questions in series and stand-alone items to familiarize candidates with the question types and formats they will encounter on the exam.
The first and only dedicated self-assessment and review tool for the Epilepsy certifying exam
Contains over 360 board-type questions with answers, detailed explanations, and references
Facilitates recall of must-know information and helps identify knowledge gaps for further study
Includes case studies and illustrated questions with 87 state-of-the-art images to ensure familiarity with findings that form a significant part of any certifying exam
When she was just 46, Christine Bryden - a brilliant biochemist, science advisor to the prime minister and single mother of three daughters - was diagnosed with early-onset dementia. Doctors told her to get her affairs in order, as she would soon be incapable of doing so. Twenty years later, she is still thriving, still working hard to rewire her brain even as it loses its function.
The unusually slow progress of her condition puts Christine in a unique position to describe the lived experience of dementia, a condition that affects 1800 new Australians each week. She shares what it's like to start grasping for words that used to come so easily. To suddenly realise you don't remember how to drive. To be exhausted from the effort of thinking, smiling, talking; of trying to appear 'normal'.
In this moving, inspiring memoir, Christine looks back on her life, in an effort to understand how her brain - once her greatest asset, now her greatest challenge - works now. She takes us through being a gifted child and then a troubled adolescent, examines how she survived a destructive marriage while enjoying a high-flying career, and shares the steps she takes to maximise her brain function. This is Christine's legacy for people with dementia and those who care for them.
Dr. Janice F. Wiesman, a neurologist with twenty years of experience helping people who have neuropathy find relief, shares her special insights into this painful and debilitating condition. With exceptional clarity, Dr. Wiesman begins by outlining the basics of nerve anatomy and function. She explains how peripheral neuropathy is diagnosed and treated, describes neuropathy’s disparate causes, and offers readers lifestyle changes that can help keep nerves healthy. A useful glossary defines terms, patient stories offer real-world experiences, and illustrations provide a visual key to the condition. A detailed resources section points the reader to reliable web sites and organizations that offer more help.
Concentrating on the most common types of neuropathy, Dr. Wiesman provides hope, help, and comfort to patients, families, and caregivers.
As neural data becomes increasingly complex, neuroscientists now require skills in computer programming, statistics, and data analysis. This book teaches practical neural data analysis techniques by presenting example datasets and developing techniques and tools for analyzing them. Each chapter begins with a specific example of neural data, which motivates mathematical and statistical analysis methods that are then applied to the data. This practical, hands-on approach is unique among data analysis textbooks and guides, and equips the reader with the tools necessary for real-world neural data analysis.
The book begins with an introduction to MATLAB, the most common programming platform in neuroscience, which is used in the book. (Readers familiar with MATLAB can skip this chapter and might decide to focus on data type or method type.) The book goes on to cover neural field data and spike train data, spectral analysis, generalized linear models, coherence, and cross-frequency coupling. Each chapter offers a stand-alone case study that can be used separately as part of a targeted investigation. The book includes some mathematical discussion but does not focus on mathematical or statistical theory, emphasizing the practical instead. References are included for readers who want to explore the theoretical more deeply. The data and accompanying MATLAB code are freely available on the authors' website. The book can be used for upper-level undergraduate or graduate courses or as a professional reference.
Every sixty-nine seconds, someone is diagnosed with Alzheimer’s disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can.
The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer’s, an inherited genetic mutation that causes the disease in one hundred percent of cases, and has a fifty percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, daughter Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer’s research and offers the brightest hope for future treatments—and possibly a cure.
Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer’s through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. “A compelling narrative…and an educational and emotional chronicle” (Kirkus Reviews, starred review), their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this inspiring race against time redefines courage in the face of this most pervasive and mysterious disease.
Here for the first time ever, social work educators Jeffrey Applegate and Janet Shapiro demystify neurobiology and present it anew with the social work audience specifically in mind. Social workers, by virtue of their work with at-risk children and families, occupy a unique position from which to employ this new research in prevention and intervention. This lack of education about neurobiology has unfortunately fostered misconceptions among social workers that these theories are too academic and thus irrelevant to clinical practice. Neurobiology for Clinical Social Work corrects this misconception and introduces social workers to the powerful and practical ideas that are coming out of neurobiological research. The research summarized here offers new insights about the crucial role that relationships play in human development and in professional helping efforts. To set the stage for this inquiry, the authors introduce fundamentals of brain structure, development, and functioning in the first parts of the book.
This introduction is intended as a primer and proceeds from the assumption that many readers are relatively unfamiliar with the field of brain science. Building on this foundation, the authors go on to describe the manner in which memory and affect regulation are neuropsychological processes. The next chapters of the book delve into the concepts of attachment. Specifically, the authors are concerned with how precursors to attachment evolve during the earliest months of an infant’s life and how various attachment classifications (secure, insecure, disorganized) lead to affect regulation—the ability of a child to regulate emotion. Throughout the book these concepts are discussed in the context of what social workers face when trying to find explanatory structures for the ways in which early childhood experiences affect later life. Later chapters turn even more directly toward practice. Using case examples—including adolescent parents and their children, children with a depressed parent, and children of substance abusing parents—Applegate and Shapiro show clinicians how to make use of neurobiological concepts in designing treatment plans and interventions. One chapter contains three extended case examples, with commentary, representing the three most common intervention models taught in schools of social work—psychodynamic, cognitive-behavioral, and systemic. Various settings, such as community mental health, family service agencies, and child welfare, are also discussed.
In order to be effective and meet the complex challenges of the twenty-first century, social work professionals must join with their colleagues in other disciplines in coordinated efforts to integrate and apply newly emerging knowledge toward the enhancement of human well-being. Neurobiology for Clinical Social Work is a great place to start this process of integration and learning.
Children with autism are challenged by the most essential human behaviors. They have difficulty interacting with other people-often failing to see people as people rather than simply objects in their environment. They cannot easily communicate ideas and feelings, have great trouble imagining what others think or feel, and in some cases spend their lives speechless. They frequently find it hard to make friends or even bond with family members. Their behavior can seem bizarre.
Education is the primary form of treatment for this mysterious condition. This means that we place important responsibilities on schools, teachers and children's parents, as well as the other professionals who work with children with autism. With the passage of the Individuals with Disabilities Education Act of 1975, we accepted responsibility for educating children who face special challenges like autism. While we have since amassed a substantial body of research, researchers have not adequately communicated with one another, and their findings have not been integrated into a proven curriculum.
Educating Children with Autism outlines an interdisciplinary approach to education for children with autism. The committee explores what makes education effective for the child with autism and identifies specific characteristics of programs that work. Recommendations are offered for choosing educational content and strategies, introducing interaction with other children, and other key areas.
This book examines some fundamental issues, including:
How children's specific diagnoses should affect educational assessment and planning How we can support the families of children with autism Features of effective instructional and comprehensive programs and strategies How we can better prepare teachers, school staffs, professionals, and parents to educate children with autism What policies at the federal, state, and local levels will best ensure appropriate education, examining strategies and resources needed to address the rights of children with autism to appropriate education.
Children with autism present educators with one of their most difficult challenges. Through a comprehensive examination of the scientific knowledge underlying educational practices, programs, and strategies, Educating Children with Autism presents valuable information for parents, administrators, advocates, researchers, and policy makers.
From bizarre dreams and hallucinations to schizophrenia and multiple personalities, the human brain is responsible for a diverse spectrum of strange thoughts and behaviors. When observed from the outside, these phenomena are often written off as being just “crazy,” but what if they were actually planned and logical?
NeuroLogic explores the brain’s internal system of reasoning, from its unconscious depths to conscious decision making, and illuminates how it explains our most outlandish as well as our most stereotyped behaviors. From sleepwalking murderers, contagious yawning, and the brains of sports fans to false memories, subliminal messages, and the secret of ticklishness, Dr. Eliezer Sternberg shows that there are patterns to the way the brain interprets the world—–patterns that fit the brain’s unique logic. Unraveling these patterns and the various ways they can be disturbed will not only alter our view of mental illness and supernatural experience, but will also shed light on the hidden parts of ourselves.
(With black-and-white illustrations throughout.)
From the Hardcover edition.
Features of Neurocritical Care Board Review include:Comprehensive, high-yield review that covers all areas tested on the neurocritical care certifying exam Applicability to a wide range of physicians in multiple specialties reviewing for boards or looking to test skills and clinical acumen in this challenging area Question and answer format with detailed explanations and references to facilitate recall of must-know information and help identify knowledge gaps for further attention Material aggregated from multiple specialties into a singular resource for exam study
The NeuroICU Board Review is a comprehensive board exam and curriculum review for the emerging specialty of neurocritical care. It delivers a through overview of neurological disease states (pathology, pathophysiology, and therapy), neurosurgery, and critical care medicine (including medical, surgical, cardiac, and cardiothoracic critical care), along with important topics such as neuromonitoring, neurosurgical emergencies, neuropharmacology, and neurosurgical post-operative care. This powerful review also includes clinical scenarios and more than 800 questions and answers with detailed answer explanations, with accompanying images, illustrations, tables, and detailed references.
• Developed for residents and practicing physicians preparing to take certifying board exams in Neurocritical Care, Surgical Critical Care, and Neurological Surgery
• More than 800 Q&A with detailed answer explanations
• Clinical scenarios show readers how to apply principles to real-world cases