Visionary physicist Geoffrey West is a pioneer in the field of complexity science, the science of emergent systems and networks. The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses.
Fascinated by aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science: West found that despite the riotous diversity in mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism’s body.
West’s work has been game-changing for biologists, but then he made the even bolder move of exploring his work’s applicability. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. Recently, West has applied his revolutionary work to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune.
Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation?
Using first-hand experience at the cutting edge of science, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge illustrates one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe.
Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden describe the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.
– Winner, Stephen Hawking Medal for Science Communication
This new edition discusses biological systems that can be analyzed quantitatively, and how advances in the life sciences have been aided by the knowledge of physical or engineering analysis techniques. The volume is organized into 18 chapters encompassing thermodynamics, electricity, optics, sound, solid mechanics, fluid mechanics, and atomic and nuclear physics. Each chapter provides a brief review of the background physics before focusing on the applications of physics to biology and medicine. Topics range from the role of diffusion in the functioning of cells to the effect of surface tension on the growth of plants in soil and the conduction of impulses along the nervous system. Each section contains problems that explore and expand some of the concepts. The text includes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics in the body.
Physics in Biology and Medicine will be a valuable resource for students and professors of physics, biology, and medicine, as well as for applied health workers.Provides practical techniques for applying knowledge of physics to the study of living systemsPresents material in a straight forward manner requiring very little background in physics or biologyIncludes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics in the body
An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.
One of the most diverse of modern scientific disciplines, biophysics applies methods and technologies from physics to the study of biological systems and phenomena, from the human nervous system to soil erosion to global warming. What are the best options for satisfying the world's growing energy demands? How can we feed the world's growing population? How can we contain, or reverse, global warming? How can we vouchsafe a plentiful supply of potable water for future generations? These are among the critical questions to which biophysicists work to provide answers.Biophysics courses are increasingly taken by students of biology, physics, chemistry, biochemistry, physiology, statistics, bioengineering, neuroscience, computer science, pharmacology, agriculture,and many more Provides a friendly, unintimidating overview of the material covered in a typical college-level biophysics course A one-stop reference, course supplement and exam preparation tool for university students currently enrolled in an introductory biophysics courses An indispensable resource for those studying the natural sciences, biological sciences, and physics, as well as math, statistics,computer science, pharmacology and many other disciplines The current job market for people well versed in biophysics is very strong, and biophysics is currently listed as one of the fast-growing occupations in the North America
The Olympics are the world's most prestigious stage for athletic competition. Fans both casual and hardcore tune in religiously every few years to watch as men and women push themselves to the limits of human performance. But what makes a champion? Is it genetics? Hours of training? A psychological advantage? Of all the athletes who dedicate their lives - and bodies - to achieving that perfect moment of triumph, why will one person or team win out over another? Science has some compelling answers, and in this book, The Science of Sports: Winning in the Olympics, Scientific American explores this topic from various angles. Beginning with Section 1: The Psychology of Winning, the book opens with a look inside the mind of an elite athlete and tackles questions of how to face a rivalry or maintain a positive attitude in the face of defeat. Other sections discuss the sticky issues surrounding genetic advantages and physical prowess, drugs and doping, injury and recovery, and - finally - the latest scientific advice for the rest of us mere mortals to be fit and healthy. You'll find both inspiration and answers in this indispensable book from the editors of Scientific American, the leading authority on science, technology and innovation.
Each chapter of the book investigates a facet of the physical world, including the drag on small projectiles; the importance of diffusion and convection; the size-dependence of acceleration; the storage, conduction, and dissipation of heat; the relationship among pressure, flow, and choice in biological pumps; and how elongate structures tune their relative twistiness and bendiness. Vogel considers design-determining factors all too commonly ignored, and builds a bridge between the world described by physics books and the reality experienced by all creatures. Glimpses of Creatures in Their Physical Worlds contains a wealth of accessible information related to functional biology, and requires little more than a basic background in secondary-school science and mathematics.
Drawing examples from creatures of land, air, and water, the book demonstrates the many uses of biological diversity and how physical forces impact biological organisms.
Advances in longevity, genetics, nanotech, and robotics will make all this possible!
This is not science fiction. This is your future. Right now, pioneering scientists and technologists are transforming what it means to be human by overcoming biological limits that have existed since our ancestors swung out of the trees…and into the suburbs. With incredible inspiration and perseverance, these visionaries are solving deep problems of human health and longevity—and their progress is accelerating. Super You takes you inside their labs, companies, and minds…to show how you can reap the benefits of a stronger, longer, better, life. You’ll learn how to start hacking your life today, to become more super, every day. Discover what’s possible when yesterday’s human limits are gone!
Learn how evolution became obsolete—and why it’s time to start hacking yourself Save your life with whirring “jet engine” hearts, printed organs, and other medical miracles Rewire and turbo-boost your ape brain Become a mega-mind by connecting your brain directly to the Internet to use Google’s synthetic neocortex Become superhuman with cyborg technology Design and mold your looks Genetically engineer your baby to be a tennis star (and other true stories) Prepare for the political and religious backlash against the future Discover how scientists will make death obsolete by treating it like a curable disease—and how to live until they do
This book is a sequel to The Rainbow and The Worm, The Physics of Organisms, which has remained in a class of its own for nearly 20 years since the publication of the first edition. Living Rainbow H2O continues the fascinating journey in the author's quest for the meaning of life, in science and beyond. Like The Rainbow and The Worm, the present book will appeal to readers in the arts and humanities as well as scientists; not least because the author herself is an occasional artist and poet. Great care has been taken to explain terms and concepts for the benefit of the general reader. At the same time, sufficient scientific details are provided in text boxes for the advanced reader and researcher without interrupting the main story.
Chapter 1: Rainbow Dancing in the Worm (299 KB)
Contents:Rainbow Dancing in the WormWeird and Wonderful WaterCooperative Coherent WaterWater and Colloid Crystals: The New Age of AlchemyQuantum Coherent WaterQED Water IQED Water II: Non-thermal EMF EffectsQED Water III: HomeopathyDancing with IonsDancing with ProteinsDancing with DNAWater at Solid InterfacesWater ElectricWater + Air = LifeWater Meets AirWater Meets MembranesThe Rainbow EnsembleTrue Portrait of the CellWater in NanospaceProtein and Water in NanospaceFire and WaterWater Fuels the Dynamo of LifeElectronic Induction Animates Life
Readership: General public and undergraduate students in cell biology, biophysics, biochemistry and quantum mechanics.
Keywords:Liquid Crystalline Water;Quantum Coherence;Quantum Cell BiologyKey Features:There is no competing title, or even comparable book in existenceIt is fit for the general reader with no more background than school science as well as the advanced researcher in the fieldIt tells an exciting, and evocative story of water in living cells and organisms that is also completely newReviews:
"This book is a delightful read for laypersons. It surveys some of the outstanding, sometimes considered anomalous properties of water and aqueous solutions. The style is consistently light, as it hops from one topic to another with a seemingly dance-like rhythm to it. Indeed, one finds many dances of water molecules among themselves, as well as with other molecules in living cells … I recommend this book to anyone who is curious about what goes on in each of our cells, and why water is so vital to our life."Arieh Ben-Naim
Hebrew University of Jerusalem, Israel
Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available.BMA Medical Book Awards 2014-Highly Commended, Basic and Clinical Sciences,2014,British Medical AssociationChapters are now divided between three interlocking sections: basic principles, structures and mechanisms, and mitochondrial physiology. Covers new advances in the structure and mechanism of key bioenergetic proteins, including complex I of the respiratory chain and transport proteins.Details cellular bioenergetics, mitochondrial cell biology and signal transduction, and the roles of mitochondria in physiology, disease and aging.Offers readers clear, visual representation of structural concepts through full colour figures throughout the book.
The sixth edition of this established text takes readers through the general background of the subject, the technical principles underlying the control of radiation hazards, radiation detection and measurement, and the biological effects of radiation. These principles are followed by a consideration of radiation protection issues in the nuclear industry, the non-nuclear sector, and the medical field. Further specialised topics include risk assessment, waste management and decommissioning, radiological incidents and emergencies, relevant legislation, and organizational issues.
Supplemented by clear diagrams and photographs, summary sections, and revision questions, the book is suitable for the beginner as well as the more advanced radiation practitioner. It remains an ideal primer for those working in the nuclear industry, nuclear medicine technicians, radiographers and medical physics technicians, health and safety executives and occupational health professionals. It is also an invaluable companion for anyone training or undertaking a course in radiation protection.
The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field.Enables practicing engineers, students and clinical professionals to understand the essential physics and signal processing techniques behind modern imaging systems as well as introducing the latest developments that will shape medical ultrasound in the futureSuitable for both newcomers and experienced readers, the practical, progressively organized applied approach is supported by hands-on MATLAB® code and worked examples that enable readers to understand the principles underlying diagnostic and therapeutic ultrasoundCovers the new important developments in the use of medical ultrasound: elastography and high-intensity therapeutic ultrasound. Many new developments are comprehensively reviewed and explained, including aberration correction, acoustic measurements, acoustic radiation force imaging, alternate imaging architectures, bioeffects: diagnostic to therapeutic, Fourier transform imaging, multimode imaging, plane wave compounding, research platforms, synthetic aperture, vector Doppler, transient shear wave elastography, ultrafast imaging and Doppler, functional ultrasound and viscoelastic models
The second edition of this bestseller has been updated to describe the latest developments in this exciting field, including a brand new chapter on force spectroscopy. The dramatic developments of AFM over the past ten years from a simple imaging tool to the multi-faceted, nano-manipulating technique that it is today are conveyed in a lively and informative narrative, which provides essential reading for students and experienced researchers alike.Contents:ApparatusBasic PrinciplesMacromoleculesInterfacial SystemsOrdered MacromoleculesCells, Tissue and BiomineralsOther Probe MicroscopesForce Spectroscopy
Readership: Undergraduates, postgraduates and researchers in biophysics.
Keywords:AFM;Scanning Probe Microscopy (SPM);Biophysics;Cells;Macromolecules;Imaging;Biopolymers;Interfaces;DNA;PhospholipidsKey Features:Over 70 new pages, 700 new references, bringing it bang up-to-date with current literature, and 24 new figuresOnly book covering published research, machines and methodology from inception to the present day (2009)Updated to include and an entirely new chapter on force spectroscopyReviews:“This second edition of an excellent book updates considerably the information contained, and is expanded, too. The main focus of this book are the biological applications of AFM, and these are covered very well … The chapters are in-depth and very informative, and contain lots of useful and detailed information. In general the book is well written with an informal style, and contains useful information for beginners, including detailed information on how to carry out some experiments, answers to common questions, etc. … Overall this book is highly recommended for those wishing to get an overview of the biological applications of AFM.”Peter Eaton
University of Porto, Portugal
Reviews of the First Edition
“This book fills an important niche by providing an introduction to AFM that will be understandable to a wide range of scientists … the reader is offered an introduction of sufficient brevity to actually be read and of sufficient depth to help in defining the potential uses of SPMs in his or her own research.”Scott Fraser (California Institute of Technology, USA)
Nature Cell Biology
“I found this book easy to read with clear, simple explanations of a complex topic. I think that the selection of the subjects treated in the book is sufficient for the non-specialist to understand both the basic concepts of the AFM and the production of AFM images in biological systems.”Microscopy and Analysis
“… is an excellent introduction for anybody wishing to enter this field … In summary I would strongly recommend this book to any biologist planning on carrying out research using SPM imaging techniques and existing users in the field who wish to broaden their knowledge of SPM imaging and the research already carried out on common biological systems.”Drew Murray
JPK Instruments, Berlin
“This book provides an excellent survey of novel applications. It is nicely illustrated with numerous images from leading experts in the field. Clear descriptions of the apparatus and its basic principles are provided in a way accessible to students/scientists who do not have a strong physics background. It will be useful to biologists, but also non-biologists dealing with biosystems …”Prof Y F Dufrêne
Tomosynthesis produces quasi-three-dimensional images that can significantly enhance the visualization of important diagnostic features. This book highlights the flexibility of tomosynthesis systems for new clinical applications, and provides a detailed discussion of the tomosynthesis acquisition process and the impact of physical factors. It explores such topics as acquisition parameters, system components, modeling, image reconstruction algorithms, and system evaluation.Provides in-depth coverage of system design considerations, as well as image reconstruction strategies Describes the current state of clinical applications of tomosynthesis, including imaging of the breast and chest, as well as its use in radiotherapy Illustrates the merits of tomosynthesis imaging and its potential clinical applications in imaging of the breast and chest, as well as for radiation therapy
Divided into five sections, this text delves into the history and development of tomosynthesis. It introduces tomosynthesis imaging, discusses imaging system design considerations, and reviews image reconstruction algorithms that have been developed for tomosynthesis. It also describes system evaluation methodologies, emphasizes current clinical applications, and examines the future direction for tomosynthesis.
The book begins with a chapter on natural history for those scientists, wild-life experts, alligator farmers, zoo keepers etc., whose primary interest is in the nature and habits of the intact alligator. This is followed by separate chapters that deal with metabolic rate, anaerobic glycolysis, digestion-growth-protein synthesis, carbohydrate metabolism, amino acid metabolism, respiration and acid-base balance, and kidney function.
This is a Print On Demand title. We no longer stock the original but will recreate a copy for you. While all efforts are made to ensure that quality is the same as the original, there may be differences in some areas of the design and packaging.
Contents:Foundations:Emergence in Physics and Biology (L E H Trainor)Holism and Reduction (C J Lumsden)Complexity: A Pluralistic Approach (W A M Brandts)Dynamics, Complexity and Computation (P A Dufort & C J Lumsden)Development: Field Approaches to Pattern Formation:Vector Field Models of Morphogenesis (W A M Brandts & J Totafurno)Symmetry Breaking Bifurcations (T M Hart & L E H Trainor)Development: Principles of Self-Organization:Generic Dynamics of Morphogenesis (B Goodwin)Toward a Model of Growth and Form in Living Systems (F Cummings)Living Organization, the Coherence of Organisms and the Morphogenetic Field (M W Ho et al.)Is Spatial Pattern Formation Homologous in Unicellular and Multicellular Organisms? (J Frankel)Cellular and Organismic Biology:Statistical Mechanics of the Main Phase Transition in Lipid Bilayers (F P Jones & P Tevlin)Multi-Neuron Interactions in Neural Network Models of Associative Memory (A E Busch & L E H Trainor)Network Hierarchies in Neural Organization, Development and Pathology (J P Sutton)Category Switching — A Neural Network Approach (L E H Trainor et al.)Evolution:A Model of Molecular Evolution Based on the Statistical Analysis of Nucleotide Sequences (L Luo)Codon Space: Exploring the Origins and Development of the Genetic Code (L E H Trainor et al.)Evolution of Development: The Shuffling of Ancient Modules by Ubiquitous Bureaucracies (E W Larsen)Game Theory in Biology (G W A Rowe)
Readership: Physicial scientists, biologists, engineers, applied mathematicians and philosophers.
keywords:Holism and Reductionism;Complexity;Symmetry;Emergent Property;Patterns;Neural Interactions;Statistical Models;Game Theory;Biology;Morphogenesis;Morphogens;Pattern Formation;Development;Epithelia Folding;Biological Modeling;Complexity;Physical Theory;Biological Regulation;Pattern Formation;Nonlinear Dynamics;Evolution;Developmental Field;Neural Networks;Collective Behavior;Genetic Code;Emergence;Reductionism;Holism;Self-Organization;Bifurcation Theory;Morphogenetic Field;Regeneration;Phase Transitions in Bilayers;Task Switching;Nucleotide Sequences;Molecular Evolution
“The important issue here is not what physics theory has done for biology (which is not very much), but what it can do in the future, and to this end the book does a marvellous job of defining the arena.”Nature
“… the scope of the articles is broad … The book should be of interest to scientists coming from biological, physical and mathematical sciences.”Bulletin for Mathematical Biology
Takes a Clear and Systematic Engineering Approach to Systems Biology
Focusing on genetic regulatory networks, Engineering Genetic Circuits presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data to learn about mathematical models, develop efficient abstraction and simulation methods to analyze these models, and use analytical methods to guide the design of new circuits.
After reviewing the basic molecular biology and biochemistry principles needed to understand genetic circuits, the book describes modern experimental techniques and methods for discovering genetic circuit models from the data generated by experiments. The next four chapters present state-of-the-art methods for analyzing these genetic circuit models. The final chapter explores how researchers are beginning to use analytical methods to design synthetic genetic circuits.
This text clearly shows how the success of systems biology depends on collaborations between engineers and biologists. From biomolecular observations to mathematical models to circuit design, it provides essential information on genetic circuits and engineering techniques that can be used to study biological systems.
Students in the physical and life sciences, and in engineering, need to know about the physics and biology of light. Recently, it has become increasingly clear that an understanding of the quantum nature of light is essential, both for the latest imaging technologies and to advance our knowledge of fundamental life processes, such as photosynthesis and human vision. From Photon to Neuron provides undergraduates with an accessible introduction to the physics of light and offers a unified view of a broad range of optical and biological phenomena. Along the way, this richly illustrated textbook builds the necessary background in neuroscience, photochemistry, and other disciplines, with applications to optogenetics, superresolution microscopy, the single-photon response of individual photoreceptor cells, and more.
With its integrated approach, From Photon to Neuron can be used as the basis for interdisciplinary courses in physics, biophysics, sensory neuroscience, biophotonics, bioengineering, or nanotechnology. The goal is always for students to gain the fluency needed to derive every result for themselves, so the book includes a wealth of exercises, including many that guide students to create computer-based solutions. Supplementary online materials include real experimental data to use with the exercises.Assumes familiarity with first-year undergraduate physics and the corresponding math Overlaps the goals of the MCAT, which now includes data-based and statistical reasoning Advanced chapters and sections also make the book suitable for graduate courses An Instructor's Guide and illustration package is available to professors
Developed by Dr. Todd A. Kuiken and Dr. Gregory A. Dumanian, targeted muscle reinnervation (TMR) is a new approach to accessing motor control signals from peripheral nerves after amputation and providing sensory feedback to prosthesis users. This practical approach has many advantages over other neural-machine interfaces for the improved control of artificial limbs. Targeted Muscle Reinnervation: A Neural Interface for Artificial Limbs provides a template for the clinical implementation of TMR and a resource for further research in this new area of science.
After describing the basic scientific concepts and key principles underlying TMR, the book presents surgical approaches to transhumeral and shoulder disarticulation amputations. It explores the possible role of TMR in the prevention and treatment of end-neuromas and details the principles of rehabilitation, prosthetic fitting, and occupational therapy for TMR patients. The book also describes transfer sensation and discusses the surgical and functional outcomes of the first several TMR patients. It concludes with emerging research on using TMR to further improve the function and quality of life for people with limb loss.
With contributions from renowned leaders in the field, including Drs. Kuiken and Dumanian, this book is a useful guide to implementing TMR in patients with high-level upper limb amputations. It also supplies the foundation to enable improvements in TMR techniques and advances in prosthetic technology.
* Chapter on the study of bioenergetics of mitochondria in the intact cell
* Appendix listing protein structure resources
* Additional colour plates of protein structures
* Many newly drawn illustrations
Both size and time ranges are so vast that multiple instrumentations must be employed, often simultaneously. As a result, a variety of highly specialized and esoteric biochemical and biophysical methodologies are often utilized. This book addresses the salient features of membranes at the molecular level, offering cohesive, foundational information for advanced undergraduate students, graduate students, biochemists, and membranologists who seek a broad overview of membrane science.Significantly expanded coverage on function, composition, and structure Brings together complex aspects of membrane research in a universally understandable mannerFeatures profiles of membrane pioneers detailing how contemporary studies originatedIncludes a timeline of important discoveries related to membrane science
This textbook gives compact introductions to the basics of the field, including molecular cell biology and statistical physics. It then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-the-art experiments and their theoretical interpretations.
The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This allows for an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.
In color throughout, the book takes readers through the history of important discoveries to the most current advances. It introduces the fundamentals of the fluorescence phenomenon and gives detailed examples of fluorescence applications in the molecular life sciences, including biochemistry, biophysics, clinical chemistry and diagnostics, pharmaceutical science, and cell and molecular biology. The author presents the basic theories underlying the applications and offers in-depth information on practical aspects.
Along with a list of references in each chapter, the text incorporates more than 250 figures that clearly illustrate the concepts and gives the chemical structures of the most widely used fluorescent molecules. In addition, the appendix provides a "Rogue’s Gallery" of the most common errors and pitfalls to avoid.
With contributions by an array of experts, topics discussed include:
Essential interactions and field coupling phenomena, highlighting their importance in research on biological effects and in scientific, industrial, and medical applications Electric field interactions in cells, focusing on ultrashort, pulsed high-intensity fields The effect of exposure to naturally occurring and human-made static, low-frequency, and pulsed magnetic fields in biological systems Dosimetry or coupling of extremely low frequency (ELF) fields into biological systems and the historical developments and recent trends in numerical dosimetry Mobile communication devices and the dosimetry or coupling of radiofrequency (RF) radiation into the human body Exposure and dosimetry associated with magnetic resonance imaging (MRI) and spectroscopy Available data on the interaction of terahertz radiation with biological tissues, cells, organelles, and molecules
There is great potential for communication, industrial, scientific, and medical use of electromagnetic fields and radiation. To help advance knowledge of the biological effects of such fields and to exploit their potential medical applications, this book highlights critical issues relating to their effects on living systems.
After covering background mathematics, physics, and digital imaging, the book presents fundamental physical principles, including magnetization and rotating reference frame. It describes how relaxation mechanisms help predict tissue contrast and how an MR signal is localized to a selected slice through the body. The text then focuses on frequency and phase encoding. It also explores the spin-echo sequence, its scan parameters, and additional imaging sequences, such as inversion recovery and gradient echo.
The authors enhance the learning experience with practical materials. Along with questions, exercises, and solutions, they include ten interactive programs on the accompanying CD-ROM. These programs not only allow concepts to be clearly demonstrated and further developed, but also provide an opportunity to engage in the learning process through guided exercises.
By providing a solid, hands-on foundation in the physics of MRI, this textbook helps students gain confidence with core concepts before they move on to further study or practical training.