While Andy deals with the outside world, more than a hundred other souls share an imaginary house inside Andy's head, struggling to maintain an orderly coexistence: Aaron, the father figure; Adam, the mischievous teenager; Jake, the frightened little boy; Aunt Sam, the artist; Seferis, the defender; and Gideon, who wants to get rid of Andy and the others and run things on his own.
Andy's new coworker, Penny Driver, is also a multiple personality, a fact that Penny is only partially aware of. When several of Penny's other souls ask Andy for help, Andy reluctantly agrees, setting in motion a chain of events that threatens to destroy the stability of the house. Now Andy and Penny must work together to uncover a terrible secret that Andy has been keeping . . . from himself.
Verily, the story Biff has to tell is a miraculous one, filled with remarkable journeys, magic, healings, kung fu, corpse reanimations, demons, and hot babes. Even the considerable wiles and devotion of the Savior's pal may not be enough to divert Joshua from his tragic destiny. But there's no one who loves Josh more -- except maybe "Maggie," Mary of Magdala -- and Biff isn't about to let his extraordinary pal suffer and ascend without a fight.