Highlights of the second edition:
The book is essential reading for those interested in the management of organisms known to interfere with the colony health of rabbits and rodents used in research protocols—including facility managers, clinical veterinarians, veterinary pathologists, and researchers.
Axel Kornerup Hansen (DVM, Dr. Vet. Sci., DipECLAM) is professor in laboratory animal science and welfare at University of Copenhagen. He is heading a research group mainly focusing on how the microbiota has an impact on laboratory animal models for inflammatory diseases and how this works in conjunction with the diet. He has published 157 peer-reviewed papers in scientific journals, and 36 other papers in books, proceedings or popular journals.
Dennis Sandris Nielsen (MSc, PhD) is associate professor at University of Copenhagen, with a special interest in gut microbiota, indigenous African fermented foods and fermented products contributing to the more joyful side of life (cocoa, wine, coffee). He is heading a research group mainly focusing on microbe-host and microbe-microbe-interactions in the mammalian gastrointestinal tract. He has published 75 peer-reviewed papers in scientific journals, and 15+ other papers in books, proceedings or popular journals.
The book breaks down techniques and procedures into modules, each of which contains a step-by-step practical and visual guide to a set of related procedures. Each description consists of a materials list, introduction, and general overview, followed by a thoroughly illustrated walkthrough of the steps for each procedure. The descriptions end with troubleshooting tips. Technical chapters are heavily illustrated and include notations of potential pitfalls and alternatives. Other chapters discuss management procedures and practices such as the hiring and training of personnel, setting fee schedules, and record keeping.
This book is a landmark resource for establishing and maintaining a facility for germ-free mouse research. Useful to both technicians and investigators, it presents every step necessary to establish a successful facility. It also gives direction in expanding multi-user facilities and applying new technologies to your current practices.
Topics discussed in this volume include:
A history of biological agents as weapons, from the use of corpses to contaminate water supplies to modern day anthrax attacks Concepts and strategies involved in biowarfare and bioterrorism The development, validation, and importance of animal models in biodefense research Infectious disease aerobiology Studies involving anthrax, glanders, plague, tularemia, Q fever, alphaviruses, orthopoxviruses, and a new chapter on brucellosis Animal models for viral hemorrhagic fevers Botulinum and Ricin toxins Staphylococcal and streptococcal superantigens
As the scientific community works diligently to protect the world’s population from the misuse of infectious organisms and toxins, it is imperative that researchers stay abreast of the latest techniques for biodefense research. Exploring in vivo and in vitro assays, this volume brings researchers up to date on the latest information on bacterial and viral infectious agents and biological toxins considered to pose the greatest threats to public safety. In addition, the contributors take a step toward minimizing the use of animals in further experiments by presenting documented findings that can be built upon.
This new volume is therefore a valuable resource for individuals engaged in the medical application of novel phage therapies.
Tricky concepts are illustrated and explained with clarity and precision, as The Human Brain Book looks at how the brain sends messages to the rest of the body, how we think and feel, how we perform unconscious actions (for example, breathing), explores the nature of genius, asks why we behave the way we do, explains how we see and hear things, and how and why we dream. Physical and psychological disorders affecting the brain and nervous system are clearly illustrated and summarized in easy-to-understand terms.
This award, first established in 1962 by the Association of Environmental and Engineering Geologists, is named in honor of Claire P. Holdredge, a founding member and the first President of the Association. The award is presented for a publication by an AEG Member(s) within the 5 previous years that is adjudged to be an outstanding contribution to the Engineering Geology profession.
Remediation of Former Manufactured Gas Plants and Other Coal-Tar Sites is geared toward environmental professionals who want to design and implement gasworks remediation strategies that offer the greatest chance to successfully protect the public. Exploring the bases for selecting remedial alternatives to adequately address today’s environmental wounds, this compendium of essential knowledge combines historic and modern scientific data and technology with common sense and empirical lore passed down from past generations of gas professionals, a group that is now all but extinct.
Most of the general population does not have a sufficient understanding of remediation needs. Unfortunately, there seems to be a similar lack of knowledge among some environmental professionals whose job it is to protect the public from the health threats associated with coal tar. Pitfalls in remediation are common and represent a significant risk to the public, especially when processes are based on inaccurate assumptions.
This book sifts through the existing scholarship from around the developed world to present the necessary evaluation factors used in effective remediation. Almost encyclopedic in scope, it offers 265 separate tables with checklists, hard data facts, and associations to help readers define site-specific gas plant conditions. It also includes a plethora of photographs and historic drawings, as well as an extensive glossary that is indispensible for understanding potential and actual gas plant contamination.
Useful for engineers, scientists, regulators, public officials, historians, and journalists among others, this book is intended for those who conduct remediation, as well as those involved in review and oversight. Its goal is to bring users closer to safely reclaiming land and reviving old coal gasworks sites in ways that ultimately will be sustainable for the public interest.