Brain and Spinal Tumors of Childhood

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Children with brain and spinal tumors account for 20-25% of childhood cancers. Until the early 1990s there had been little progress in the development of new treatments, and outcomes were not improving despite advances seen in other childhood cancers. During the past 10 years, however, there has been a dramatic increase in interest in the subject among pediatric specialists worldwide, and new multi-disciplinary teams have become established. There are encouraging early signs of improvement in outcomes, and more are anticipated.

The appearance of this comprehensive, but practical, evidence-based review of brain and spinal tumors in children is therefore very timely. The content includes detailed coverage of the diagnosis, clinical management, after care and monitoring, and underlying biology of brain and spinal tumors in children. International in approach, it draws on the experience of the European Childhood Brain Tumour Committee, linked to the International Society of Paediatric Oncology, and various multi-centre clinical trials to reflect the various approaches to management that have arisen around the world.
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About the author

David A. Walker BMedSci BM BS FRCP FRCPCH
Reader and Honorary Consultant in Paediatric Oncology, Division of Child Health, School of Human Development, University of Nottingham, Queen's Medical Centre, Nottingham, UK

Giorgio Perilongo MD
Consultant Paediatric Oncologist, Neuro-oncology Program, Division of Hematology/Oncology, Department of Pediatrics, University Hospital of Padova, Italy

Jonathan A. G. Punt MB BS FRCS FRCPCH
Formerly Senior Lecturer in Paediatric Neurosurgery and Consultant Paediatric Neurosurgeon, Children's Brain Tumour Research Centre, Nottingham, UK

Roger E. Taylor MA MB BS FRCP(Edin) FRCP FRCR
Consultant Clinical (Radiation) Oncologist, Cookridge Hospital, Leeds, UK
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Additional Information

CRC Press
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Published on
Jul 30, 2004
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Best For
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Medical / Oncology
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Content Protection
This content is DRM protected.
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Eligible for Family Library

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Tis text has resulted from some forty years of experience during which the author has puzzled over the meaning of ore textures. Te learning process has been slow and is still incomplete. Te bemusement began directly upon leaving the academic confnes, which in retrospect lef one keen young geologist very ill-equipped to interpret the mineralising process via feld or hand lens style observation of the rocks. Enlightenment has proceeded via a series of events:- 1. Te slow process of feld observation as an industry-based mine and exploration geologist. 2. Te opportunity to visit numerous diferent styles of ore deposit both as an academic and consultant. 3. Te need to answer questions from several generations of enquiring students. 4. Te privilege of being able to conduct research. 5. Te good fortune to be associated with a few top class economic geologists who actually knew what they were doing! Professor Willard C. Lacy deserves the most credit for quietly demonstrating the value of frst principles concerning fuid channelways, combined with an ability to look properly at the t- tures. Despite rapid technological advances this skill remains fundamental both to the practi- ing exploration geologist and to the academic researcher who is interested in understanding ore forming processes. Te fve volumes comprising this presentation were originally compiled individually over a period of eleven years, and aimed to progressively guide the observer though the principles of recogn-i tion concerning infll, alteration, overprinting, and fnally to ore-related breccias.
With a new foreword by Dr. Dominic D'Agostino, PhD and epilogue by the author

A masterful synchronization of history and cutting-edge science shines new light on humanity's darkest diagnosis.

In the wake of the Cancer Genome Atlas project's failure to provide a legible roadmap to a cure for cancer, science writer Travis Christofferson illuminates a promising blend of old and new perspectives on the disease. Tripping over the Truth follows the story of cancer’s proposed metabolic origin from the vaunted halls of the German scientific golden age to modern laboratories around the world. The reader is taken on a journey through time and science that results in an unlikely connecting of the dots with profound therapeutic implications.

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With contributions from Thomas Seyfried, PhD, author of Cancer as a Metabolic Disease; Miriam Kalamian, EdM, MS, CNS, author of Keto for Cancer; and Beth Zupec Kania, consultant nutritionist of The Charlie Foundation.

First published in 1829, Walker's Appeal called on slaves to rise up and free themselves. The two subsequent versions of his document (including the reprinted 1830 edition published shortly before Walker's death) were increasingly radical. Addressed to the whole world but directed primarily to people of color around the world, the 87-page pamphlet by a free black man born in North Carolina and living in Boston advocates immediate emancipation and slave rebellion. Walker asks the slaves among his readers whether they wouldn't prefer to "be killed than to be a slave to a tyrant." He advises them not to "trifle" if they do rise up, but rather to kill those who would continue to enslave them and their wives and children. Copies of the pamphlet were smuggled by ship in 1830 from Boston to Wilmington, North Carolina, Walker's childhood home, causing panic among whites. In 1830, members of North Carolina's General Assembly had the Appeal in mind as they tightened the state's laws dealing with slaves and free black citizens. The resulting stricter laws led to more policies that repressed African Americans, freed and slave alike.

A DOCSOUTH BOOK. This collaboration between UNC Press and the University of North Carolina at Chapel Hill Library brings classic works back into print. DocSouth Books editions are selected from the digital library of Documenting the American South and are unaltered from the original publication. The DocSouth series uses digital technology to offer e-books and print-on-demand publications, providing affordable and accessible editions to a new generation of scholars, students, and general readers.

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