Handbook of Near-Infrared Analysis: Edition 3

CRC Press
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Fast, inexpensive, and easy-to-use, near-infrared (NIR) spectroscopy can be used to analyze small samples of virtually any composition. The Handbook of Near Infrared Analysis, Third Edition explains how to perform accurate as well as time- and cost-effective analyses across a growing spectrum of disciplines.

Presenting nearly 50% new and revised material, this thoroughly updated edition incorporates the latest advances in instrumentation, computerization, calibration, and method development in NIR spectroscopy. The book underscores current trends in sample preparation, calibration transfer, process control, data analysis, and commercial NIR instrumentation. New chapters highlight novel applications including the analysis of agro-forestry products, polymers, blood, and control serum. They also cover NIR spectra, process analytical technologies (PAT), quantitative and qualitative analyses for nutraceuticals, NIR photography uses in medicine, and counterfeit detection methods for pharmaceuticals and currency.

Offering the most complete single-source guide of its kind, the Handbook of Near Infrared Analysis, Third Edition continues to offer practicing chemists and spectroscopists an unparalleled combination of theoretical foundations, cutting-edge applications, and practical experience provided firsthand by more than 60 experts in the field.
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Additional Information

Publisher
CRC Press
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Published on
Sep 7, 2007
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Pages
834
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ISBN
9781420007374
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Best For
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Language
English
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Genres
Science / Chemistry / Analytic
Science / Chemistry / Industrial & Technical
Science / Research & Methodology
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Content Protection
This content is DRM protected.
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Eligible for Family Library

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Since the completion of the first edition of this book, major developments have occurred in the pharmaceutical industry that have shaped the field of near-infrared (NIR) spectroscopy. A new initiative from the U.S. Food and Drug Administration (FDA) to modernize regulations of pharmaceutical manufacturing and drug quality has helped position NIR spectroscopy as an effective tool for pharmaceutical testing. Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy: Second Edition reflects these developments and brings readers an up-to-date summary of how this technique is being applied to pharmaceutical manufacturing.

Topics include:

The origins and principles of NIR spectroscopy, including early instrumentation, spectroscopic theory, and light-particle interaction The physics of each instrument type, the strengths and weaknesses of each, and the manufacturers that produce them The possible advantages of using NIR methods for monitoring or controlling blending, as well as practical concerns for mixing processes NIR spectroscopy as applied to traditional granulation, drug layering, and film coating of beads or granules Pharmaceutical assays, including qualitative analysis, quantitative analysis, determination of actives in tablets and capsules, and considerations for intact dosage form analysis Steps involved in the validation and acceptance of an NIR spectroscopy method, including quality assurance, qualification and verification of instruments, and the International Conference on Harmonization (ICH) guidelines Medical applications, including those related to blood glucose measurements, tissue and major organ analysis, fetal analysis, and cancer research

Providing comprehensive coverage of NIR spectroscopy, from theory, mathematics, application, and mechanics of NIR analysis, the book supplies ample references to facilitate further research into this burgeoning field.

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