Information technology supports efficient operations, enterprise integration, and seamless value delivery, yet itself is too often inefficient, un-integrated, and of unclear value. This completely rewritten version of the bestselling Architecture and Patterns for IT Service Management, Resource Planning and Governance retains the original (and still unique) approach: apply the discipline of enterprise architecture to the business of large scale IT management itself. Author Charles Betz applies his deep practitioner experience to a critical reading of ITIL 2011, COBIT version 4, the CMMI suite, the IT portfolio management literature, and the Agile/Lean IT convergence, and derives a value stream analysis, IT semantic model, and enabling systems architecture (covering current topics such as CMDB/CMS, Service Catalog, and IT Portfolio Management). Using the concept of design patterns, the book then presents dozens of visual models documenting challenging problems in integrating IT management, showing how process, data, and IT management systems must work together to enable IT and its business partners. The edition retains the fundamental discipline of traceable process, data, and system analysis that has made the first edition a favored desk reference for IT process analysts around the world. This best seller is a must read for anyone charged with enterprise architecture, IT planning, or IT governance and management.Lean-oriented process analysis of IT management, carefully distinguished from an IT functional modelField-tested conceptual information model with definitions and usage scenarios, mapped to both the process and system architecturesIntegrated architecture for IT management systemsSynthesizes Enterprise Architecture, IT Service Management, and IT Portfolio Management in a practical way
This third edition of A Dictionary of Virology offers an authoritative, concise, and up-to-date list of all viruses affecting vertebrate species, from humans to fish. It has been completely revised since the 1997 edition to include 25% more entries, including many completely new viruses. The entries have been restructured so that all viruses are listed and classified in accordance with the standards set by the 7th Report of the ICTV. The extensive cross-referencing and illustrative tables further enhance the utility of this reference.
Volume II completes the description of the main aspects of the theory, covering representation questions, model theory and decision problems for them, translations from logic to algebra and vice-versa, and relationships with other algebraic versions of logic.
Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field.
* Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level
This book deals with numerical methods for solving large sparse linear systems of equations, particularly those arising from the discretization of partial differential equations. It covers both direct and iterative methods. Direct methods which are considered are variants of Gaussian elimination and fast solvers for separable partial differential equations in rectangular domains. The book reviews the classical iterative methods like Jacobi, Gauss-Seidel and alternating directions algorithms. A particular emphasis is put on the conjugate gradient as well as conjugate gradient -like methods for non symmetric problems. Most efficient preconditioners used to speed up convergence are studied. A chapter is devoted to the multigrid method and the book ends with domain decomposition algorithms that are well suited for solving linear systems on parallel computers.
Endocrine Methods contains descriptions of contemporary and cutting-edge methodologies in various areas of endocrinology, including receptor theory and immunologic techniques for endocrine research. The book presents step-by-step procedures easily available to study the endocrine system and includes experts in their respective fields as contributors. The book presents step-by-step procedures for many important areas of endocrine target organs. Endocrine Methods serves as a valuable methodological resource for investigators using endocrine methods.
Includes comprehensive, yet rapid methodical procedures Offers a wide spectrum of assays including both in vivo and in vitro systems important to the several areas of hormone research Describes several techniques for studying receptors, examining osteoblast activity, and measuring parathyroid hormones Encompasses a host of important research tools that can be utilized by the toxicologist and other biomedical scientists
This informative treatise offers a concise collection of existing, expert data summarizing the composition of milk. The Handbook of Milk Composition summarizes current information on all aspects of human and bovine milk, including: sampling, storage, composition, as well as specific chapters on major and minor components such as protein, carbohydrates, lipids, electrolytes, minerals, vitamins and hormones. The book also features comprehensive coverage of compartmentation, host-defense components, factors affecting composition, composition of commercial formulas, and contaminants.
* Reliable data on the composition of human and bovine milks. * Discusses the many factors affecting composition. * Composition tables make up 25-30% of the total book. * Problems concerning sampling and analysis are described. * Should appeal equally to industry and academia. * Also of interest to developing countries in need of information on infant nutrition and agricultural development
High Resolution NMR: Theory and Chemical Applications, Second Edition covers the significant progress in understanding the NMR phenomena, instrumentation, and applications in chemical and biochemistry.
This edition is divided into 14 chapters and begins with the historical developments and theoretical aspects of NMR. Considerable chapters are devoted to the basic principles, chemical shifts, coupling constants, and analysis of complex spectra. Other chapters contain expanded topics on carbon-13, nuclear Overhauser effect, relaxation mechanisms, and the use of superconducting magnets. The remaining chapters examine the concepts of solvent effects, hydrogen bonding, and the use of NMR in quantitative analysis.
This book will prove useful to analytical chemists, biochemists, and researchers.
High performance capillary electrophoresis (HPCE) is the newest and perhaps most powerful separation technique available today. This single-authored text provides an integrated, comprehensive, and clearly illustrated look at the field. Users of HPCE will gain a basic understanding of principles underlying electrophoresis and go on to learn about mode selection, methods development, detection, and quantative analysis. Ideally suited for analytical chemists and analytical biochemists with applications involving small molecules, proteins, peptides, DNA, and ion separations, this book provides a comparative assessment of related techniques. The author is an internationally recognised scientist and serves as the instructor for short courses on HPCE as offered by the American Chemical Society.
* Stresses basic principles and applications * Helps users select appropriate HPCE modes and develop methods * Describes how to perform quantitative analyses * reinforces concepts with clear illustrations
This book is a collection of tried and tested laboratory protocols for the isolation and characterization of mammalian RNA. It studies cellular regulation using RNA as a parameter of gene express, offers RNA isolation strategies, and explains proper handling, storage, and manipulation of RNA.
* Studies cellular regulation using RNA as a parameter of Gene Expression * Offers RNA isolation strategies * Explains proper handling, storage, and manipulation of RNA
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