Infection, Immune Homeostasis and Immune Privilege

Springer Science & Business Media
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Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms.

This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

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Additional Information

Publisher
Springer Science & Business Media
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Published on
Jul 3, 2012
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Pages
156
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ISBN
9783034804455
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Language
English
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Genres
Medical / General
Medical / Microbiology
Medical / Research
Science / Life Sciences / Molecular Biology
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Content Protection
This content is DRM protected.
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