Importantly, the slides are editable, so they can be readily adapted to a lecturer’s personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content.
The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: email@example.com
“Professor Joe” - as he is called by his students - is a Distinguished Professor of Computer Science and Medicine and Chair of the Computational & Systems Biology Interdepartmental Program at UCLA - an undergraduate research-oriented program he nurtured and honed over several decades. As an active full-time member of the UCLA faculty for nearly half a century, he also developed and led innovative graduate PhD programs, including Computational Systems Biology in Computer Science, and Biosystem Science and Engineering in Biomedical Engineering. He has mentored students from these programs since 1968, as Director of the UCLA Biocybernetics Laboratory, and was awarded the prestigious UCLA Distinguished Teaching Award and Eby Award for Creative Teaching in 2003, and the Lockeed-Martin Award for Teaching Excellence in 2004. Professor Joe also is a Fellow of the Biomedical Engineering Society. Visiting professorships included stints at universities in Canada, Italy, Sweden and the UK and he was a Senior Fulbright-Hays Scholar in Italy in 1979.
Professor Joe has been very active in the publishing world. As an editor, he founded and was Editor-in-Chief of the Modeling Methodology Forum - a department in seven of the American Journals of Physiology - from 1984 thru 1991. As a writer, he authored or coauthored both editions of Feedback and Control Systems (Schaum-McGraw-Hill 1967 and 1990), more than 200 research articles, and recently published his opus textbook: Dynamic Systems Biology Modeling and Simulation (Academic Press/Elsevier November 2013 and February 2014).
Much of his research has been based on integrating experimental neuroendocrine and metabolism studies in mammals and fishes with data-driven mathematical modeling methodology - strongly motivated by his experiences in “wet-lab”. His seminal contributions to modeling theory and practice are in structural identifiability (parameter ambiguity) analysis, driven by experimental encumbrances. He introduced the notions of interval and quasi-identifiablity of unidentifiable dynamic system models, and his lab has developed symbolic algorithmic approaches and new internet software (web app COMBOS) for computing identifiable parameter combinations. These are the aggregate parts of otherwise unidentifiable models that can be quantified - with broad application in model reduction (simplification) and experiment design. His long-term contributions to quantitative understanding of thyroid hormone production and metabolism in mammals and fishes have recently been crystallized into web app THYROSIM - for internet-based research and teaching about thyroid hormone dynamics in humans.
Last but not least, Professor Joe is a passionate straight-ahead jazz saxophone player (alto and tenor), an alternate career begun in the 1950s in NYC at Stuyvesant High School - temporarily suspended when he started undergrad school, and resumed again in middle-age. He recently added flute to his practice schedule and he and his band - Acoustically Speaking -can be found occasionally gigging in Los Angeles or Honolulu haunts.
In this practical and comprehensive guide, author Martin Kleppmann helps you navigate this diverse landscape by examining the pros and cons of various technologies for processing and storing data. Software keeps changing, but the fundamental principles remain the same. With this book, software engineers and architects will learn how to apply those ideas in practice, and how to make full use of data in modern applications.Peer under the hood of the systems you already use, and learn how to use and operate them more effectivelyMake informed decisions by identifying the strengths and weaknesses of different toolsNavigate the trade-offs around consistency, scalability, fault tolerance, and complexityUnderstand the distributed systems research upon which modern databases are builtPeek behind the scenes of major online services, and learn from their architectures
If you have an aptitude for mathematics and some programming skills, author Joel Grus will help you get comfortable with the math and statistics at the core of data science, and with hacking skills you need to get started as a data scientist. Today’s messy glut of data holds answers to questions no one’s even thought to ask. This book provides you with the know-how to dig those answers out.Get a crash course in PythonLearn the basics of linear algebra, statistics, and probability—and understand how and when they're used in data scienceCollect, explore, clean, munge, and manipulate dataDive into the fundamentals of machine learningImplement models such as k-nearest Neighbors, Naive Bayes, linear and logistic regression, decision trees, neural networks, and clusteringExplore recommender systems, natural language processing, network analysis, MapReduce, and databases
Written by Wes McKinney, the creator of the Python pandas project, this book is a practical, modern introduction to data science tools in Python. It’s ideal for analysts new to Python and for Python programmers new to data science and scientific computing. Data files and related material are available on GitHub.Use the IPython shell and Jupyter notebook for exploratory computingLearn basic and advanced features in NumPy (Numerical Python)Get started with data analysis tools in the pandas libraryUse flexible tools to load, clean, transform, merge, and reshape dataCreate informative visualizations with matplotlibApply the pandas groupby facility to slice, dice, and summarize datasetsAnalyze and manipulate regular and irregular time series dataLearn how to solve real-world data analysis problems with thorough, detailed examples
Each recipe addresses a specific problem, with a discussion that explains the solution and offers insight into how it works. If you’re a beginner, R Cookbook will help get you started. If you’re an experienced data programmer, it will jog your memory and expand your horizons. You’ll get the job done faster and learn more about R in the process.Create vectors, handle variables, and perform other basic functionsInput and output dataTackle data structures such as matrices, lists, factors, and data framesWork with probability, probability distributions, and random variablesCalculate statistics and confidence intervals, and perform statistical testsCreate a variety of graphic displaysBuild statistical models with linear regressions and analysis of variance (ANOVA)Explore advanced statistical techniques, such as finding clusters in your data
"Wonderfully readable, R Cookbook serves not only as a solutions manual of sorts, but as a truly enjoyable way to explore the R language—one practical example at a time."—Jeffrey Ryan, software consultant and R package author