Lifespan: Why We Age—and Why We Don't Have To

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A NEW YORK TIMES BESTSELLER

A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people.

It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?

In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”

This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger.

Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
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About the author

David Sinclair, PhD, AO is a professor of genetics at Harvard Medical School. One of the leading innovators of his generation, he has been named by Time as “one of the 100 most influential people in the world” and top 50 most influential people in healthcare. He is a board member of the American Federation for Aging Research and has received more than 35 awards for his research and major scientific breakthroughs. Dr. Sinclair and his work have been featured on 60 Minutes, Today, The Wall Street Journal, The New York Times, Fortune, and Newsweek, among others. He lives in Boston and enjoys hiking and kayaking with his wife and three children. To learn more, visit LifespanBook.com and follow him on Twitter @DavidASinclair.

Matthew LaPlante is an associate professor of journalistic writing at Utah State University, where he teaches news reporting and feature writing. A former US Navy intelligence specialist and Middle East war correspondent, he is the author of Superlative: The Biology of Extremes and the cowriter of multiple other books on the intersection of science and society. He lives in Salt Lake City and skis in Big Cottonwood Canyon. To learn more, visit MDLaPlante.com and follow him on Twitter @MDLaPlante.
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Additional Information

Publisher
Simon and Schuster
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Published on
Sep 10, 2019
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Pages
432
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ISBN
9781501191992
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Language
English
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Genres
Health & Fitness / Diseases / Genetic
Health & Fitness / Longevity
Science / Life Sciences / Genetics & Genomics
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Content Protection
This content is DRM protected.
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Eligible for Family Library

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The 1,150 pages contain more information than any other comparable book. It is not a glossary or dictionary or review because all concepts are explained, not just defined or mentioned.Covers the latest developments, usually missed in textbooks and monographs.The broad range of modern genetics, of cell and molecular biology, biometry, etc. are included without glossing over the classical foundations.The hundreds of simple and clear illustrations are vey useful for classroom purposes because they can be drawn on the blackboard or projected on a screen without taking much time to make the crucial points.The cross-references among the entries tie the contents into an extremely useful comprehensive textbook.The concise style leads the reader to the point without verbiage.The etymology of the terms is explained.The text is not intimidating and it is very easy to read because all the terms are explained within the book. Most of the biometrical procedures are presented by worked-out examples in a plain form, rarely or not found at all in other books.It effectively reaches out to non-geneticists without compromising high scientific standards. Usually the most essential features of a concept are presented at the beginning of the entry, and the reader can go as far as she/he feels needed about the logic.The WEB and e-mail addresses of databases and other sources of detailed information are very helpful.A well selected list of about 1000 references, published mainly in the last couple of years, completes the volume.The moderate price makes it a best buy, and an excellent choice to own for students, teachers, scientists, physicians, lawyers and all educated persons who cannot afford an entire library yet wish to be well informed.
The internationally renowned, clinically tested, revolutionary diet program to lose weight, fight disease, and live a longer, healthier life.
 
Can what you eat determine how long, and how well, you live? The clinically proven answer is yes, and The Longevity Diet is easier to follow than you'd think. The culmination of 25 years of research on aging, nutrition, and disease across the globe, this unique program lays out a simple solution to living to a healthy old age through nutrition. The key is combining the healthy everyday eating plan the book outlines, with the scientifically engineered fasting-mimicking diet, or FMD; the FMD, done just 3-4 times a year, does away with the misery and starvation most of us experience while fasting, allowing you to reap all the beneficial health effects of a restrictive diet, while avoiding negative stressors, like low energy and sleeplessness. Valter Longo, director of the Longevity Institute at USC and the Program on Longevity and Cancer at IFOM in Milan, designed the FMD after making a series of remarkable discoveries in mice, then in humans, indicating that specific diets can activate stem cells and promote regeneration and rejuvenation in multiple organs to significantly reduce risk for diabetes, cancer, Alzheimer’s, and heart disease. Longo’s simple pescatarian daily eating plan and the periodic fasting-mimicking techniques can both yield impressive results. Low in proteins and sugars and rich in healthy fats and plant-based foods, The Longevity Diet is proven to help you: 
 
   • Lose weight and reduce abdominal fat
   • Extend your healthy lifespan with simple everyday changes
   • Prevent age-related muscle and bone loss
   • Build your resistance to diabetes, cardiovascular disease, Alzheimer's and cancer
 
Longo’s healthy, life span-extending program is based on an easy-to-adopt pescatarian plan along with the fasting-mimicking diet no more than 4 times a year, just 5 days at a time. Including 30 easy recipes for an everyday diet based on Longo's five pillars of longevity, The Longevity Diet is the key to living a longer, healthier, more fulfilled life.
*Los Angeles Times bestseller*

“If hygge is the art of doing nothing, ikigai is the art of doing something—and doing it with supreme focus and joy.” —New York Post

Bring meaning and joy to all your days with this internationally bestselling guide to the Japanese concept of ikigai (pronounced ee-key-guy)—the happiness of always being busy—as revealed by the daily habits of the world’s longest-living people.

What’s your ikigai?

“Only staying active will make you want to live a hundred years.” —Japanese proverb
 
According to the Japanese, everyone has an ikigai—a reason for living. And according to the residents of the Japanese village with the world’s longest-living people, finding it is the key to a happier and longer life. Having a strong sense of ikigai—the place where passion, mission, vocation, and profession intersect—means that each day is infused with meaning. It’s the reason we get up in the morning. It’s also the reason many Japanese never really retire (in fact there’s no word in Japanese that means retire in the sense it does in English): They remain active and work at what they enjoy, because they’ve found a real purpose in life—the happiness of always being busy.
 
In researching this book, the authors interviewed the residents of the Japanese village with the highest percentage of 100-year-olds—one of the world’s Blue Zones. Ikigai reveals the secrets to their longevity and happiness: how they eat, how they move, how they work, how they foster collaboration and community, and—their best-kept secret—how they find the ikigai that brings satisfaction to their lives. And it provides practical tools to help you discover your own ikigai. Because who doesn’t want to find happiness in every day?
From Bulletproof creator and bestselling author Dave Asprey comes a revolutionary approach to anti-aging that will help you up your game at any age.

** New York Times Bestseller **

Dave Asprey suffered countless symptoms of aging as a young man, which sparked a life-long burning desire to grow younger with each birthday. For more than twenty years, he has been on a quest to find innovative, science-backed methods to upgrade human biology and redefine the limits of the mind, body, and spirit. The results speak for themselves. Now in his forties, Dave is smarter, happier, and more fit and successful than ever before.

In Super Human, he shows how this is level of health and performance possible for all of us. While we assume we will peak in middle age and then decline, Asprey’s research reveals there is another way. It is possible to make changes on the sub-cellular level to dramatically extend life span. And the tools to live longer also give you more energy and brainpower right now.

The answers lie in Dave’s Seven Pillars of Aging that contribute to degeneration and disease while diminishing your performance in the moment. Using simple interventions—like diet, sleep, light, exercise, and little-known but powerful hacks from ozone therapy to proper jaw alignment, you can decelerate cellular aging and supercharge your body’s ability to heal and rejuvenate.?

A self-proclaimed human guinea pig, Asprey arms readers with practical advice to maximize their lives at every age with his signature mix of science-geek wonder, candor, and enthusiasm. Getting older no longer has to mean decline. Now it’s an opportunity to become Super Human.

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