Basic Concepts in Medicinal Chemistry

ASHP
2
Free sample

Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation.

In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group.

Key features include:
• Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups.
• How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism.
• Numerous examples and expanded discussions for complex concepts.
• Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice.
• An overview of structure activity relationships (SARs) and concepts that govern drug design.
• Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix.

Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry.

About the Authors

Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS"  (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy.

Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.

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About the author


Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also a multi-year recipient of the "TOPS"  (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy.

Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
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Additional Information

Publisher
ASHP
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Published on
Jan 18, 2013
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Pages
460
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ISBN
9781585283644
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Language
English
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Genres
Medical / Pharmacy
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Content Protection
This content is DRM protected.
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This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals.

The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals.

The volume many important aspects of medicinal chemistry, including

techniques in drug discovery pharmacological aspects of natural products chemical mediators: druggable targets advances in medicinal chemistry

The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration..

Topics include:

drug design drug discovery natural products and supplements and nutraceuticals pharmaceutical approaches to sexual dysfunction drug resistance parasites new natural compounds and identification of new targets stereochemistry aspects in medicinal chemistry common drug interactions in daily practices

Handbook of Research on Medicinal Chemistry: Innovations and Methodologies

will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.
Covering everything you need to study for and pass the Pharmacy Technician Certification Board (PTCB) and ExCPT exams, Mosby's Review for the Pharmacy Technician Certification Examination, 3rd Edition makes exam preparation easy. Review the content you'll see on the exam with handy outlines, test-taking tips and strategies, and electronic flash cards. Written by noted pharmacy technician educator James J. Mizner, this complete review tests your knowledge and simulates the actual PTCB exam with 17 different, 100-question practice exams in the book and online. This edition is modeled after the updated Pharmacy Technician Certification Exam Blueprint.A total of 1,700 review questions are included in 17 practice exams in the book and online.100-question format of each practice exam simulates the PTCB and ExCPT exams, with multiple-choice questions and the same balance of content, for a realistic test taking experience.700 electronic flash cards help you learn and remember facts by covering the top 200 most prescribed pharmaceuticals, top 50 herbals, abbreviations, and sound-alike drugs.Review content reflects the new percentages covered on the PTCB exam.A convenient outline format helps you to quickly review important information you'll see on the exam.Tips and suggestions prepare you for test-taking success by providing an insider’s perspective on what to expect and how to prepare for your exam when you have limited time. Seven practice exams in the book feature the same format and content emphasis as the national exam. Ten practice exams on the Evolve companion website in both timed and untimed modes help you identify any areas of weakness, and include instant feedback and remediation. UPDATED content includes current drug information and pharmacy practice procedures based on the new Pharmacy Technician Certification Exam Blueprint.NEW! Chapter objectives provide a clear breakdown of content and goals for review.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.


The guide pharmacists and students turn to first for cutting-edge coverage of drug information

A Doody’s Core Title for 2019!

The goal of Drug Information: A Guide for Pharmacists, Sixth Edition is to teach students and practitioners how to effectively research, interpret, evaluate, collate, and disseminate drug information in the most efficient and effective manner possible. Updated to reflect the realities of today’s practice, the book also addresses important issues such as the legal and ethical considerations of providing drug information.

Drug Information: A Guide for Pharmacists begins by introducing the concept of drug information, including its history, and provides details on the various places drug information specialists may find employment. This is followed by information on how to answer a question, from the process of gathering necessary background information through determining the actual informational need, to answering the question. The chapter on drug information resources includes descriptions of the most commonly used references and contains new information on apps available to practitioners. As with past editions, practical examples are also provided.

The Sixth Edition has been updated throughout, with chapters from previous editions rearranged to make the subject flow better. This edition is also enhanced by the addition of new chapters on journal clubs and counterfeit drugs/drug shortages. In addition, coverage of Policy Development, Project Design and Implementation has been greatly expanded.



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