Compendium of Organic Synthetic Methods

Compendium of Organic Synthetic Methods

Book 12
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The Compendium of Organic Synthetic Methods series facilitates theworking chemist's search for the most useful functional grouptransformations in organic chemistry. Drawn from an exhaustivesurvey of the literature, Compendium of Organic Synthetic Methods,Volume 12 contains both functional group transformations andcarbon-carbon bond-forming reactions. Author Michael Smith adheresto stringent criteria for listing reactions, including realsynthetic utility and reagents that are either readily available oreasily prepared and handled in the laboratory.

A clear organizational scheme-chemical transformations classifiedfirst by reacting functional group of starting material, then byfunctional group formed-allows for quick reference and informationretrieval. Compendium of Organic Synthetic Methods, Volume 12provides an unparalleled source of information on the methods,reactions, and transformations in contemporary organic chemistryfor the working chemist and student alike.
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About the author

Michael B. Smith is Professor of Chemistry at the University of Connecticut at Storrs. He is the author of Volumes 6–11 of the Compendium of Organic Synthetic Methods, coauthor of the fifth and sixth editions of March's Advanced Organic Chemistry, with Jerry March, and author of Organic Synthesis, Second Edition as well as several monographs.

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Additional Information

Publisher
John Wiley & Sons
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Published on
Aug 13, 2009
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Pages
594
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ISBN
9780470503850
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Best For
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Language
English
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Genres
Science / Chemistry / Organic
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Content Protection
This content is DRM protected.
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The new, revised and updated 7th edition ofMarch’s Advanced Organic Chemistry clearly explainsthe theories and examples of organic chemistry, providing the mostcomprehensive resource about organic chemistry available.

Readers are guided on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions. The first five chapters deal with the structure oforganic compounds and discuss important organic chemistrybonds, fundamental principles of conformation, and stereochemistryof organic molecules, and reactive intermediates in organicchemistry. Chapters 6 to 9 are concerned with generalprinciples of mechanism in organic chemistry, including acids andbases, photochemistry, sonochemistry and microwave irradiation, andfinally the relationship between structure and reactivity. Thelast 10 chapters cover the nature and the scope of organicreactions and their mechanisms.

The 7th edition proves again it is a must-havedesktop reference and textbook for every student and professionalworking in organic chemistry or related fields.

Key features of the 7th edition:

Every chapter has been updated with the most recent reactioninformation with references to both the primary and reviewliteratureNew to the 7th edition: 5,500 references since the lastedition, updates / rewrites of the retained sections, and anupdated index in Appendix BContains more than 1650 reactions and 20,000 valuablereferences to the primary literatureIncludes appendices on the literature of organic chemistry andthe classification of reactions according to the compoundssynthesizedGuides the reader on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions. 

Reviews of the previous edition:

"...a favorite general organic chemistry text and an easy-to-useone-volume reference. We are confident that this book will remain adominant reference and that it will reside on many chemists'personal bookshelves." –Journal of MedicinalChemistry

"Who can hope to be seriously accepted as a member of theorganic chemistry community without being in possession of at leastone edition of 'March'?" –Chemistry and Industry

Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid-base concepts, Organic Chemistry: An Acid–Base Approach provides a framework for understanding the subject that goes beyond mere memorization. The individual steps in many important mechanisms rely on acid–base reactions, and the ability to see these relationships makes understanding organic chemistry easier. Using several techniques to develop a relational understanding, this textbook helps students fully grasp the essential concepts at the root of organic chemistry.

Providing a practical learning experience with numerous opportunities for self-testing, the book contains:

Checklists of what students need to know before they begin to study a topic Checklists of concepts to be fully understood before moving to the next subject area Homework problems directly tied to each concept at the end of each chapter Embedded problems with answers throughout the material Experimental details and mechanisms for key reactions

The reactions and mechanisms contained in the book describe the most fundamental concepts that are used in industry, biological chemistry and biochemistry, molecular biology, and pharmacy. The concepts presented constitute the fundamental basis of life processes, making them critical to the study of medicine. Reflecting this emphasis, most chapters end with a brief section that describes biological applications for each concept. This text provides students with the skills to proceed to the next level of study, offering a fundamental understanding of acids and bases applied to organic transformations and organic molecules.

The new, revised and updated 7th edition ofMarch’s Advanced Organic Chemistry clearly explainsthe theories and examples of organic chemistry, providing the mostcomprehensive resource about organic chemistry available.

Readers are guided on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions. The first five chapters deal with the structure oforganic compounds and discuss important organic chemistrybonds, fundamental principles of conformation, and stereochemistryof organic molecules, and reactive intermediates in organicchemistry. Chapters 6 to 9 are concerned with generalprinciples of mechanism in organic chemistry, including acids andbases, photochemistry, sonochemistry and microwave irradiation, andfinally the relationship between structure and reactivity. Thelast 10 chapters cover the nature and the scope of organicreactions and their mechanisms.

The 7th edition proves again it is a must-havedesktop reference and textbook for every student and professionalworking in organic chemistry or related fields.

Key features of the 7th edition:

Every chapter has been updated with the most recent reactioninformation with references to both the primary and reviewliteratureNew to the 7th edition: 5,500 references since the lastedition, updates / rewrites of the retained sections, and anupdated index in Appendix BContains more than 1650 reactions and 20,000 valuablereferences to the primary literatureIncludes appendices on the literature of organic chemistry andthe classification of reactions according to the compoundssynthesizedGuides the reader on planning and execution of multi-stepsynthetic reactions, with detailed descriptions of all thereactions. 

Reviews of the previous edition:

"...a favorite general organic chemistry text and an easy-to-useone-volume reference. We are confident that this book will remain adominant reference and that it will reside on many chemists'personal bookshelves." –Journal of MedicinalChemistry

"Who can hope to be seriously accepted as a member of theorganic chemistry community without being in possession of at leastone edition of 'March'?" –Chemistry and Industry

A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined.

To save students much time catching up this text provides a reliable and readily available source for background material that will enable all graduate students to reach the same high level of proficiency in organic chemistry. Produced over many years with extensive feedback from students taking an organic chemistry course this book provides a reaction based approach. The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to ‘disconnect’ a bigger molecule into simpler building blocks.

Most chapters include an extensive list of questions to test the reader’s understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists.

The book is intended for graduate and postgraduate students, scientific researchers in chemistry

New publisher, new edition; extensively updated and corrected Over 950 new references with more than 6100 references in total Over 600 new reactions and figures replaced or updatedOver 300 new homework problems from the current literature to provide nearly 800 problems to test reader understanding of the key principles
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