In this classic of Japanese SF from 1964, American astronauts on a space mission discover a strange virus and bring it to Earth, where rogue scientists transform it into a fatal version of the flu. After the virulent virus is released, nearly all human life on Earth is wiped out save for just ten thousand men and a handful of women living in research stations in Antarctica. Then one of the researchers realizes that a major earthquake in the now-depopulated United States may lead to nuclear Armageddon... -- VIZ Media
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