Corporate Comedy

Notion Press
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The saber-rattling ‘Knight’ and the family lore of the ‘Errant Father’ make for amusing reading. How did the ‘Mermaid’ with its superlative striking power end up in its watery grave? The action packed account of the conquest of ‘Mount Everest’ floating in the Bay of Bengal is a thrilling experience. The ‘Smoke Stack Tyrant’ and the ‘Tin Soldier’ are relics of a corporate culture in bygone years. What did Gurucharan find in the meadows where the eves graze? Corporate Comedy is all that you need for a guilty pleasure – an interesting narrative married to anecdotes, warped and woven, with a subtle sense of humour.
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About the author

Thobias is a natural in storytelling. He is an engineer turned salesman. His journey through the corridors of public sector undertakings in India brought him in contact with many interesting persons and hilarious episodes. The story teller in him found profound meaning in many of these episodes and enchanted his colleagues and friends with his unique narrative style. This debut attempt at writing filled up the void in his retirement.
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Additional Information

Notion Press
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Published on
Feb 4, 2017
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Fiction / Humorous / General
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Content Protection
This content is DRM free.
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In one complete volume, here are the five classic novels from Douglas Adams’s beloved Hitchhiker series.

The Hitchhiker’s Guide to the Galaxy
Seconds before the Earth is demolished for a galactic freeway, Arthur Dent is saved by Ford Prefect, a researcher for the revised Guide. Together they stick out their thumbs to the stars and begin a wild journey through time and space.

The Restaurant at the End of the Universe
The moment before annihilation at the hands of warmongers is a curious time to crave tea. It could only happen to the cosmically displaced Arthur Dent and his comrades as they hurtle across the galaxy in a desperate search for a place to eat.

Life, the Universe and Everything
The unhappy inhabitants of planet Krikkit are sick of looking at the night sky– so they plan to destroy it. The universe, that is. Now only five individuals can avert Armageddon: mild-mannered Arthur Dent and his stalwart crew.

So Long, and Thanks for All the Fish
Back on Earth, Arthur Dent is ready to believe that the past eight years were all just a figment of his stressed-out imagination. But a gift-wrapped fishbowl with a cryptic inscription thrusts him back to reality. So to speak.

Mostly Harmless
Just when Arthur Dent makes the terrible mistake of starting to enjoy life, all hell breaks loose. Can he save the Earth from total obliteration? Can he save the Guide from a hostile alien takeover? Can he save his daughter from herself?

Includes the bonus story “Young Zaphod Plays It Safe”

“With droll wit, a keen eye for detail and heavy doses of insight . . . Adams makes us laugh until we cry.”—San Diego Union-Tribune

“Lively, sharply satirical, brilliantly written . . . ranks with the best set pieces in Mark Twain.”—The Atlantic
Janet Evanovich’s #1 New York Times bestselling sensation Stephanie Plum returns in her twenty-forth thriller as mutilated corpses litter the streets of New Jersey... 

Trouble comes in bunches for Stephanie Plum. First, professional grave robber and semi-professional loon, Simon Diggery, won’t let her take him in until she agrees to care for his boa constrictor, Ethel. Stephanie’s main qualification for babysitting an extremely large snake is that she owns a stun gun—whether that’s for use on the wandering serpent or the petrified neighbors remains to be seen.

Events take a dark turn when headless bodies start appearing across town. At first, it’s just corpses from a funeral home and the morgue that have had the heads removed. But when a homeless man is murdered and dumped behind a church Stephanie knows that she’s the only one with a prayer of catching this killer.

If all that’s not enough, Diesel’s back in town. The 6-foot-tall, blonde-haired hunk is a man who accepts no limits—that includes locked doors, closed windows and underwear. Trenton’s hottest cop, Joe Morelli isn’t pleased at this unexpected arrival nor is Ranger, the high-powered security consultant who has his own plans for Stephanie.

As usual Jersey’s favorite bounty hunter is stuck in the middle with more questions than answers. What’s the deal with Grandma Mazur’s latest online paramour? Who is behind the startling epidemic of mutilated corpses? And is the enigmatic Diesel’s sudden appearance a coincidence or the cause of recent deadly events?  
The amount and distribution of adipose and lean tissues has been shown to be predictive of mortality and morbidity in metabolic disease. Traditionally these risks are assessed by anthropometric measurements based on weight, length, girths or the body mass index (BMI). These measurements are predictive of risks on a population level, where a too low or a too high BMI indicates an increased risk of both mortality and morbidity. However, today a large part of the world’s population belongs to a group with an elevated risk according to BMI, many of which will live long and healthy lives. Thus, better instruments are needed to properly direct health-care resources to those who need it the most.

Medical imaging method can go beyond anthropometrics. Tomographic modalities, such as magnetic resonance imaging (MRI), can measure how we have stored fat in and around organs. These measurements can eventually lead to better individual risk predictions. For instance, a tendency to store fat as visceral adipose tissue (VAT) is associated with an increased risk of diabetes type 2, cardio-vascular disease, liver disease and certain types of cancer. Furthermore, liver fat is associated with liver disease, diabetes type 2. Brown adipose tissue (BAT), is another emerging component of body-composition analysis. While the normal white adipose tissue stores fat, BAT burns energy to produce heat. This unique property makes BAT highly interesting, from a metabolic point of view.

Magnetic resonance imaging can both accurately and safely measure internal adipose tissue compartments, and the fat infiltration of organs. Which is why MRI is often considered the reference method for non-invasive body-composition analysis. The two major challenges of MRI based body-composition analysis are, the between-scanner reproducibility and a cost-effective analysis of the images. This thesis presents a complete implementation of fat-referenced MRI, a technique that produces quantitative images that can increase both inter-scanner and automation of the image analysis.

With MRI, it is possible to construct images where water and fat are separated into paired images. In these images, it easy to depict adipose tissue and lean tissue structures. This thesis takes water-fat MRI one step further, by introducing a quantitative framework called fat-referenced MRI. By calibrating the image using the subjects' own adipose tissue (paper II), the otherwise non-quantitative fat images are made quantitative. In these fat-referenced images it is possible to directly measure the amount of adipose tissue in different compartments. This quantitative property makes image analysis easy and accurate, as lean and adipose tissues can be separated on a sub-voxel level. Fat-referenced MRI further allows the quantification and characterization of BAT.

This thesis work starts by formulating a method to produce water-fat images (paper I) based on two gradient recall images, i.e.\ 2-point Dixon images (2PD). It furthers shows that fat-referenced 2PD images can be corrected for T2*, making the 2PD body-composition measurements comparable with confounder-corrected Dixon measurements (paper III}).

Both the water-fat separation method and fat image calibration are applied to BAT imaging. The methodology is first evaluated in an animal model, where it is shown that it can detect both BAT browning and volume increase following cold acclimatization (paper IV). It is then applied to postmortem imaging, were it is used to locate interscapular BAT in human infants (paper V). Subsequent analysis of biopsies, taken based on the MRI images, showed that the interscapular BAT was of a type not previously believed to exist in humans. In the last study, fat-referenced MRI is applied to BAT imaging of adults. As BAT structures are difficult to locate in many adults, the methodology was also extended with a multi-atlas segmentation methods (paper VI).

In summary, this thesis shows that fat-referenced MRI is a quantitative method that can be used for body-composition analysis. It also shows that fat-referenced MRI can produce quantitative high-resolution images, a necessity for many BAT applications.

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