Fundamentals of Toxicologic Pathology: Edition 2

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Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology).

Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists.

  • 25% brand new information, fully revised throughout
  • New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology
  • New color photomicrographs detailing specific toxicant-induced diseases in animals
  • Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
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About the author

Professor Haschek-Hock has served as president of the Society of Toxicologic Pathology and the Society of Toxicology’s Comparative and Veterinary Specialty Section, as well as Councilor of the American College of Veterinary Pathologists, board member of the American Board of Toxicology; as Associate Editor for Toxicological Sciences and for Toxicologic Pathology; as Editorial Board member for Fundamental and Applied Toxicology, Veterinary Pathology and Toxicologic Pathology. She has served as a member on the USFDA Veterinary Medicine Advisory Committee for the Center for Veterinary Medicine, the EPA’s FIFRA Science Advisory Panel, and National Academy of Sciences Committee. She currently serves on the Board of Directors of the C.L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology. She was awarded the Society of Toxicologic Pathology’s Achievement Award in 2007 and the Midwest Regional Chapter - Society of Toxicology’s Kenneth DuBois Award in 2011.
-Diplomate of the American College of Veterinary Pathologists (ACVP)
-Diplomate of the American Board of Toxicology (ABT)
-Fellow of the International Academy of Toxicologic Pathologists (FIATP)

Professor Rousseaux is a Fellow of the Royal College of Pathology, Diplomate of the American Board of Toxicology, Fellow of the Academy of Toxicological Sciences, and Fellow of the International Academy of Toxicologic Pathology. He is Professor (Adjunct) in the Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Canada. He has 35 years of experience in comparative and toxicologic pathology with a research focus on herbal remedies, fetal development and teratology, and environmental pollutants. He has described, investigated, and evaluated numerous toxicologic pathology issues associated with pharmaceutical, pesticides, and agrochemicals. He has served on the editorial board of Toxicologic Pathology. He is a former president of the Society of Toxicologic Pathology.

Professor Wallig is a Diplomate of the American College of Veterinary Pathologists. He is Professor Emeritus in the Department of Pathobiology, College of Veterinary Medicine, the Department of Food Science and Human Nutrition, as well as the Division of Nutritional Sciences at the University of Illinois. His research has focused on the chemoprotective properties and mechanisms of phytochemicals in the diet, in particular those in cruciferous vegetables and soy, and the pathophysiology of pancreatic injury.

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Additional Information

Publisher
Academic Press
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Published on
Nov 23, 2009
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Pages
714
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ISBN
9780080919324
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Language
English
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Genres
Medical / Pathology
Medical / Toxicology
Medical / Veterinary Medicine / General
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Content Protection
This content is DRM protected.
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Read Aloud
Available on Android devices
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Eligible for Family Library

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Diagnose and manage diseases using the newest information and research! Pathologic Basis of Veterinary Disease – Expert Consult, 6th Edition provides complete, illustrated coverage of both general pathology and the pathology of organ systems of domestic animals. Addressing species from dogs and cats to pigs and cattle — and many more — this reference describes the lesions and pathogeneses of diseases, how cells and tissues respond to injury, and the interplay of host defense mechanisms with microbes and injurious agents. Updates include the latest scientific advances and diagnostic information. Written by a team of expert contributors, this book includes an Expert Consult website with access to the complete digital book plus thousands of images and guidelines for sample acquisition and for performing a complete necropsy.Complete coverage of both general pathology and pathology of organ systems is provided in one convenient resource, and includes the latest information available.Over 20 recognized experts deliver the most relevant information for the practitioner, student, or individual preparing for the American College of Veterinary Pathology board examination.UPDATED content on cellular and organ system pathology includes the latest insights into the science of inflammation, healing, and molecular carcinogenesis, as well as expanded coverage of genetics and disease. Over 2,100 full-color illustrations include color schematics, flow charts, and diagrammatic representations of disease processes as well as summary tables and boxes, making it easier to understand difficult concepts.Clear, up-to-date explanations of disease mechanisms describe cell, tissue, and organ response to injury and infection.Easy-to-follow organization for each systemic disease chapter includes a brief review of basic principles related to anatomy, structure, and function, followed by congenital and functional abnormalities and discussions of infectious disease responses, helping you apply principles to veterinary practice.Expert Consult website provides the reader with the complete digital text plus: An image collection; guidelines for performing a complete, systematic necropsy and appropriate sample acquisition for all organ systems; a comprehensive glossary; and an appendix of photographic techniques in veterinary pathology. NEW line drawings and schematic diagrams depict current concepts about pathogeneses and lesions of veterinary diseases.NEW! Essential Concept boxes in each basic pathology chapter break down long and complicated topics, making it easier to understand lesions and pathogeneses in the ‘organ system’ chapters. NEW! Key Readings Index at the beginning of each chapter includes page numbers, making important information easy to locate.
A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology.
This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury.

Key Features
* Easy to find, up-to-date reference information
* Graphic and photographic plates
* Current hot topics and anticipated changes in toxicologic pathology
* Standardized chapter format
* Topics that are addressed in both a broad and deep manner, resulting in a stand alone text
* Added coverage of important environmental toxicants
* Chapters authored by internationally recognized experts and peer-reviewed
A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology.
This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury.

Key Features
* Easy to find, up-to-date reference information
* Graphic and photographic plates
* Current hot topics and anticipated changes in toxicologic pathology
* Standardized chapter format
* Topics that are addressed in both a broad and deep manner, resulting in a stand alone text
* Added coverage of important environmental toxicants
* Chapters authored by internationally recognized experts and peer-reviewed
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