Emily Ho is the endowed director of the Moore Family Center for Whole Grain Foods, Nutrition and Preventive Health. She is a full professor in the College of Public Health and Human Sciences, with an emphasis in nutrition, and is a principal investigator at the Linus Pauling Institute at Oregon State University. She joined the Oregon State University faculty in 2003 after receiving her Ph.D in human nutrition from the Ohio State University and completing her postdoctoral research at Children's Hospital Oakland Research Institute and UC Berkeley. During the course of her career, Dr. Ho has published 97 peer-reviewed articles and abstracts and four book chapters. She has been invited to give more than 40 presentations and has mentored more than 40 undergraduate and graduate students. She currently serves on the editorial board for Journal of Nutritional Biochemistry and Frontiers in Epigenomics. Her research interests are in the area of antioxidants and gene expression and dietary chemoprevention strategies. More specifically, she focuses on the effects of zinc status on DNA damage, DNA repair, and stress-response signal pathways. Another major focus in her laboratory is investigating the genetic and epigenetic mechanisms by which foods such as soy, tea, and cruciferous vegetables may protect against prostate cancer.
Frederick Domannis a professor of radiation oncology in the Free Radical and Radiation Biology Program at the University of Iowa. He is a distinguished alumnus from the University of Wisconsin where he earned his Ph.D in 1991 in human cancer biology under Kelly H. Clifton, studying radiation-induced thyroid and mammary carcinogenesis. He subsequently pursued postdoctoral research at the Arizona Cancer Center with G. Tim Bowden, where he studied the redox biology of gene expression. He joined the faculty at the University of Iowa in 1993 and has since become an internationally recognized expert in free ra
The editors have built Advances in Vitamin B Deficiency Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Vitamin B Deficiency in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Vitamin B Deficiency Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility.
Nutrition in Epigenetics is divided into two primary parts. The first part provides key principles such as epigenetic mechanisms, developmental epigenetics, and the role of epigenetics in disease. The second part looks specifically at the application of epigenetics to the field of human nutrition. Chapters review the role of specific nutrients in modulating epigenetic status and the effect on health and disease.
Nutrition in Epigenetics is an indispensable resource for researchers, professionals and advanced students with an interest in human nutrition, epigenetics, and biomedical research.
Selected topics from this field have been covered in some books, but no other comprehensive text on epigenetics, nutrition, and human health and disease is available, until now. This book illustrates nutrition’s influence on epigenetic inheritance and the mechanisms underlying the modification of the metabolic imprint of an individual. This enriched understanding of nutrigenomics can be applied to master a tailored diet that can alleviate imprinted metabolic syndromes. Specifically, the book focuses on:Maternal, perinatal, and neonatal nutrition Epigenetic mechanisms and cancer Impacts of dietary factors, folate deficiency and DNA methylation Nutrition’s influence on genetic imprinting The basics of nutrigenomics and epigenetic regulation
Profiling the latest evidence of their impact on various human pathological conditions, the book summarizes current thinking with regard to the biotransformation and conjugation of individual compounds in the gastrointestinal tract, liver, large intestine, and cells. It highlights a topic that has been largely ignored—namely the extent to which dietary phenolics components undergo metabolism in the large intestine. It also explores the generation of bacterially derived metabolites. Individual chapters discuss which metabolites enter the circulatory system and are likely to offer protective actions against human diseases.
Edited by internationally recognized leaders in the field, the book presents contributions by a panel of experts who demonstrate the potential of flavonoids in ameliorating a range of disease states, including cardiovascular disease, Alzheimer’s and Parkinson’s disease and other neurodegenerative disorders, and cancer. The research presented in this volume provides a reliable starting point for further inquiry and experimentation.
Current research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigenetic phenomena and the fascinating implications of diet on this largely uncharted field.
Generously laden with tables and illustrations, many in color, this book addresses how nutrients alter physiologic and pathologic processes in the human body through epigenetic changes without affecting the DNA sequence. It also explains the detailed molecular structures of epigenetic phenomena and closely examines the current knowledge surrounding the biology of aging and embryonic growth regulation.
Assesses the Likelihood of Clinical Applicability
In one single compendium, this resource delineates the nutritional factors that further much-studied aberrant epigenetic patterns, such as DNA methylation, histone modifications, and chromatin remodeling. The book spotlights the influence of nutrition on epigenetic gene regulation, opening the way for counteracting future disease processes associated with epigenetic phenomena—a step that could potentially change the face of disease prevention and development.