But California voters said "YES!" to a $3 billion stem cell research program: the awkwardly-named California Institute for Regenerative Medicine (CIRM). Born into battle, the scrappy little state agency was immediately blocked by three years of anti-science lawsuits -- but it defeated them all. And then?
A quiet triumph. With a focused intensity like the Manhattan Project (but for peaceful purposes, not to build a bomb), scientists funded by CIRM took on the challenges: disease and disability called chronic: incurable.
In a series of connected stories, accurate though written to entertain, "California Cures" relates a war: science against disease, with lives on the line. Think what it means for a paralyzed young man to recover the use of his hands, or for a formerly-blind mother to see her teenaged children -- for the first time!
Do you know the "bubble-baby" syndrome? Infants without a proper immune system typically die young; a common cold can kill. But for eighteen babies in a stem cell clinical trial, a different future: they were cured of their disease.
No one can predict the pace of science, nor say when cures will come; but California is bringing the fight. The reader will meet the scientists involved, the women and men behind the microscope, and share their struggle.
Above all, "California Cures" is a call for action. Washington may argue about the expense of health care (and who will get it), but California works to bring down the mountain of medical debt: stem cell therapies to ease suffering, and save lives.
Will California build on success -- and invest $5 billion more in stem cell research?
"We have the momentum," says author Don C Reed, "We dare not stop short. Chronic disease threatens everyone -- we are fighting for your family, and mine!"Contents: Introduction: Evangelina and the Golden StateThe Absolute Minimum You Need to Know FirstTo Breathe, or Not to BreatheThe Strongest Man in the WorldWhen the Dolphin Broke My EarThe Boy with Butterfly SkinThe Great Baldness "Comb-Over" Replacement?"He Sees! He Sees!"Cop at the Window"Go West, Young (Wo)Man" -- To a Biomed Career?And How Will You be Paying for that New Heart?The Answer to Cancer?A Political Obstacle to Heart Disease Cure?Your Friend, the Liver!"Bring 'em Back Alive"The Color of FatRevenge for My SisterA Story with No Happy Ending?Aging and Stem CellsThe "Impending Alzheimer's Healthcare Disaster"President Trump's Great Stem Cell OpportunityLeiningen's Ants and Parkinson's DiseaseOn the Morality of Fetal Cell ResearchDemocracy and Gloria's KneesThree Children, and the Eternal FlameAutism, Mini-Brains, and the Zika VirusWhy "The Big Bang Theory" Matters to MeMusashi and the Two-Sword Solution"The Magnificent Seven"The Connecticut CommitmentIn Memory of BeauTo Relocate Alligators, or Turn a Country on to Biomed?Whale Sharks and Outer SpaceMr Science Goes to Washington?When Oklahoma is Not OkJames Bond and MelanomaNeurological Diseases vs. CaliforniaDriving to the StormDoor into TomorrowStem Cell Battles -- On Times Square?Annette, Richard Pryor, and Multiple SclerosisMike Pence, and Reproductive ServitudeMotorcycle Wrecks and Complex FracturesEven Dracula Gets ArthritisTugboat for CureWheelchair Warriors, Take Back Your Rights!Sickle Cell Dis
This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed. This book provides an comprehensive update on the advancement in the field of stem cells and regenerative medicine, and serves as a valuable resource for both researchers and students.
It is difficult even for experts to find out what has already reached a clinical stage. The aim of the second volume in this series is to provide the reader with a current update on the latest therapeutic developments. As such, both patients and doctors will find the information contained within this manual to be useful and relevant. The editors are both international leaders in the field of regenerative medicine, and both possess a broad spectrum of experience from basic research to clinical application and commercialization.
This book will present the main findings to date and the important factors to be considered when considering resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin, and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate.Highlights basic research in tissue specific stem cells, experiments with animal models and clinical trials that are transforming the field of regenerationProvides a clear understanding of endogenous stem cells, their role in current regenerative therapies, and prospects for future researchReports on the main-stream clinical approaches and in vivo experiments published in primary literature to help categorizes the advances in various aspects of regenerative therapy and illustrate opportunities for clinical applications
In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
Brilliant color presentation
Avoiding the overwhelming details found in many engineering and physics texts, this groundbreaking book—in color throughout—includes only the most essential formulas as well as many noncalculation-based exercises. Important terms are highlighted in bold and defined in a glossary. The text contains more than 400 color figures, most of which are from the original researchers.
Coverage of both historical perspectives and the latest developments
Developed from the author’s long-running course, this classroom-tested text gives readers a vivid picture of how the field has grown by presenting historical perspectives and a timeline of seminal discoveries. It also describes numerous state-of-the-art biomedical applications that benefit from "going small," including devices that record the electrical activity of brain cells, measure the diffusion of molecules in microfluidic channels, and allow for high-throughput studies of gene expression.