In narrating the history of research that contributed to diagnostic genetic medicine, Hogan describes the expanding scope of prenatal diagnosis and prevention. He draws on case studies of Prader-Willi, fragile X, DiGeorge, and velo-cardio-facial syndromes to illustrate that almost all testing in medical genetics is inseparable from the larger—and increasingly "big data"–oriented—aims of biomedical research. Hogan also reveals how contemporary genetic testing infrastructure reflects an intense collaboration among cytogeneticists, molecular biologists, and doctors specializing in human malformation.
Hogan critiques the modern ideology of genetic prevention, which suggests that all pregnancies are at risk for genetic disease and should be subject to extensive genomic screening. He examines the dilemmas and ethics of the use of prenatal diagnostic information in an era when medical geneticists and biotechnology companies have begun offering whole genome prenatal screening—essentially searching for any disease-causing mutation. Hogan’s focus and analysis is animated by ongoing scientific and scholarly debates about the extent to which the preventive focus in contemporary medical genetics resembles the aims of earlier eugenicists. Written for historians, sociologists, and anthropologists of science and medicine, as well as bioethics scholars, physicians, geneticists, and families affected by genetic conditions, Life Histories of Genetic Disease is a profound exploration of the scientific culture surrounding malformation and mutation.
Focusing principally on medically relevant areas of genetics rather than the underlying basic science and technological aspects, the book offers a fascinating insight for those working and training in the field of clinical or laboratory aspects of medical genetics, genomics and allied areas; it will also be of interest to historians of science and medicine and to workers in the social sciences who are increasingly attracted by the social and ethical challenges posed by modern medical genetics and genomics.
In a series of detective-style stories, Goldstein explores the priestly lineage of Jewish males as manifested by Y chromosomes; the Jewish lineage claims of the Lemba, an obscure black South African tribe; the differences in maternal and paternal genetic heritage among Jewish populations; and much more. The author also grapples with the medical and ethical implications of our rapidly growing command of the human genomic landscape. The study of genetics has not only changed the study of Jewish history, Goldstein shows, it has altered notions of Jewish identity and even our understanding of what makes a people a people.
"My road to atheism was paved by science . . . but, ironically, so was my later journey to God," Strobel says.
During his academic years, Lee Strobel became convinced that God was obsolete, a belief that colored his journalism career. Science had made the idea of a Creator irrelevant - or so Strobel thought.
But today science points in a different direction. A diverse and impressive body of research has increasingly supported the conclusion that the universe was intelligently designed. At the same time, Darwinism has faltered in the face of concrete facts and hard reason. Has science discovered God? At the very least, it's giving faith an immense boost, as new findings emerge about the incredible complexity of our universe.
Join Strobel as he reexamines the theories that once led him away from God. Through his compelling and highly readable account, you’ll encounter the mind-stretching discoveries from cosmology, cellular biology, DNA research, astronomy, physics, and human consciousness that present astonishing evidence in The Case for a Creator.
Also available: The Case for a Creator small group video study and study guide, Spanish edition, kids' edition, student edition, and more.