Genome tells the story of the most ambitious scientific adventure of our time. By gradually isolating and identifying all the genes in the human body—the blueprint for life—scientists are closing in on the ability to effectively treat and prevent nearly every disease that strikes man, from muscular dystrophy, diabetes, and cancer to heart ailments, alcoholism, and even mental illness.
Such discoveries will change the course of human life. At the same time, they raise profound ethical questions that have tremendous implications: Can insurance companies demand genetic tests to determine who poses a health risk? Should parents be able to choose their baby’s sex or eye color? Will employers screen out potential employees who are genetically susceptible to occupational health problems?
An exciting true tale of discovery that is revolutionizing our world, Genome helps us understand our future.
Why are rates of conditions like autism, asthma, obesity, and allergies exploding at an unprecedented pace? Why are humans living longer, getting smarter, and having far fewer kids? How might your lifestyle affect your unborn children and grandchildren? How will gene-editing technologies like CRISPR steer the course of human evolution? If Darwin were alive today, how would he explain this new world? Could our progeny eventually become a different species—or several?
In Evolving Ourselves, futurist Juan Enriquez and scientist Steve Gullans conduct a sweeping tour of how humans are changing the course of evolution—sometimes intentionally, sometimes not. For example:
• Globally, rates of obesity in humans nearly doubled between 1980 and 2014. What’s more, there’s evidence that other species, from pasture-fed horses to lab animals to house cats, are also getting fatter.
• As reported by U.S. government agencies, the rate of autism rose by 131 percent from 2001 to 2010, an increase that cannot be attributed simply to increases in diagnosis rates.
• Three hundred years ago, almost no one with a serious nut allergy lived long enough to reproduce. Today, despite an environment in which food allergies have increased by 50 percent in just over a decade, 17 million Americans who suffer from food allergies survive, thrive, and pass their genes and behaviors on to the next generation.
• In the pre-Twinkie era, early humans had quite healthy mouths. As we began cooking, bathing, and using antibiotics, the bacteria in our bodies changed dramatically and became far less diverse. Today the consequences are evident not only in our teeth but throughout our bodies and minds.
Though these harbingers of change are deeply unsettling, the authors argue that we are also in an epoch of tremendous opportunity. New advances in biotechnology help us mitigate the cruel forces of natural selection, from saving prematurely born babies to gene therapies for sickle cell anemia and other conditions. As technology like CRISPR enables us to take control of our genes, we will be able to alter our own species and many others—a good thing, given that our eventual survival will require space travel and colonization, enabled by a fundamental redesign of our bodies.
Future humans could become great caretakers of the planet, as well as a more diverse, more resilient, gentler, and more intelligent species—but only if we make the right choices now.
Intelligent, provocative, and optimistic, Evolving Ourselves is the ultimate guide to the next phase of life on Earth.
From the Hardcover edition.
A second goal of this book is to present work in the field without bias toward any particular statistical paradigm.
Broadly speaking, the essays in this Handbook are concerned with problems of induction, statistics and probability. For centuries, foundational problems like induction have been among philosophers’ favorite topics; recently, however, non-philosophers have increasingly taken a keen interest in these issues. This volume accordingly contains papers by both philosophers and non-philosophers, including scholars from nine academic disciplines.Provides a bridge between philosophy and current scientific findingsCovers theory and applicationsEncourages multi-disciplinary dialogue
"Sober's is the answering philosophical voice, the voice of a first-rate philosopher and a knowledgeable student of contemporary evolutionary theory. His book merits broad attention among both communities. It should also inspire others to continue the conversation."-Philip Kitcher, Nature
"Elliott Sober has made extraordinarily important contributions to our understanding of biological problems in evolutionary biology and causality. The Nature of Selection is a major contribution to understanding epistemological problems in evolutionary theory. I predict that it will have a long lasting place in the literature."-Richard C. Lewontin