The World Health Organization (WHO) has declared obesity a global epidemic. Its prevalence has more than doubled since 1980, causing a myriad of health problems for children and adults. Obesity: Epidemiology, Pathophysiology, and Prevention, Second Edition explores the molecular mechanisms and pathophysiology leading to obesity and metabolic disorders. It examines the safety of obesity drugs and drug development strategies as well as the role of physical activity, nutrition, and nutraceutical supplements in obesity treatment and prevention.
With contributions from a cadre of internationally known experts, the book covers a spectrum of essential topics related to this widespread phenomenon, including:
The relationship between obesity and type 2 diabetes The addiction mechanism related to refined foods as a significant factor in obesity The correlation between obesity and environmental estrogens, endocrine disruption, cigarette smoking, and inflammatory response The role of drug and chemical toxicities and genomic imprinting disorders in obesity The safety and regulation of prescription and over-the-counter weight loss drugs Various diets, the glycemic index, and the role of exercise in treating or preventing obesity Controversy over effective vs. banned weight loss supplements Childhood obesity and its prevention Bariatric surgery for weight management and reversal of metabolic disorders
As the public has become more aware of the deadly adverse effects of obesity, numerous products and programs have targeted the overweight and obese population, many with dangerous side effects. It is essential that we develop strategic, therapeutic intervention supported by credible data. This volume is an ideal reference point for researchers looking for new avenues of inquiry and practicing medical professionals, clinical nutritionists, and dietitians seeking guidance for their patients.
Beginning with insights into the scope, importance and growing opportunities in these industries, the book demonstrates the global scenario on the acceptance and demand for nutraceuticals and functional foods. It explores the regulatory hurdles and claim substantiation of these foods and dietary supplements, as well as the intricate aspects of manufacturing procedures.
Including regulations from South America, Canada, European Union, Australia, New Zealand, Africa, Japan, Korea, China, India and Southeast Asia as well as the United States, Nutraceutical and Functional Food Regulations in the United States and Around the World provides a valuable resource for understanding the key considerations of operating in this rapidly expanding area.
*Overview of nutraceutical and functional food regulations around the world
*Discusses the important of GRAS status and DSHEA regulations
*Provides insight on quality manufacturing techniques, cGMP and standardized analytical techniques
*Includes salient features on overcoming regulatory hurdles
*Addresses the importance of safety, efficacy and human clinical studies for worldwide acceptance
*Highlights anti-terrorism safety assurance through traceability
*Explores the significance of intellectual property, trademark and branding on marketing
1. This book will cover the multi-faceted factors contributing to the rapidly growing childhood obesity epidemic.
2. The underlying causes and current status of rapidly growing obesity epidemic in children in the global scenario will be discussed.
3. The strategies for childhood obesity prevention and treatment such as physical activity and exercise, personalized nutrition plans and school and community involvement will be presented.
1. A comprehensive and concise book addressing the global epidemic of childhood obesity targeted for nutritionists, dieticians, medical and health professionals, educators and scientists.
2. The strategies for childhood obesity prevention and treatment such as physical activity and exercise, personalized nutrition plans and school and community involvement will be presented.
3. The impact and its consequences of this ongoing epidemic on individual family and community as a whole will be addressed.
Nutrition and Enhanced Sports Performance: Muscle Building, Endurance, and Strength provides a comprehensive overview to understanding the integrated impact of nutrition on performance. The book is divided into five main themes:An introductory overview of the role of nutrition in human healthVarious types of physical exercises, including cardiovascular training, resistance training, aerobic and anaerobic exercise, bioenergetics, and energy balance. This section also covers the nutritional requirements associated with various fitness programs, as well as exercise and nutritional requirements in special populations, including the pre-pubertal, young, elderly, and disabled. Sports and nutritional requirements.The molecular mechanisms involved in muscle building A thorough review of various food, minerals, supplements, phytochemicals, amino acids, transition metals, small molecules and other ergogenic agents that have been implicated in muscle building and human performance
This book is an ideal resource for nutritionists, dietitians, exercise physiologists, health practitioners, researchers, students, athletes, trainers, and all those who wish to broaden their knowledge of nutrition and its role in human performance.
Discusses the impact of nutrition, including food, minerals, vitamins, hormones, trace elements, etc., that can significantly attenuate/improve human performance and sportsAddresses the molecular and cellular pathways involved in the physiology of muscle growth and the mechanisms by which nutrients affect muscle health, growth and maintenanceEncompasses multiple forms of sports/performance and the salient contribution of appropriate nutrition on special populations, including nutritional guidelines and recommendations to athletesStrong focus on muscle building
Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases.
Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes.
Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndromeIncludes coverage of Pre-diabetes conditions plus both Type I and Type II DiabetesPresents both prevention and treatment options
Bio-nanotechnology is the key functional technology of the 21st century. It is a fusion of biology and nanotechnology based on the principles and chemical pathways of living organisms, and refers to the functional applications of biomolecules in nanotechnology. It encompasses the study, creation, and illumination of the connections between structural molecular biology, nutrition and nanotechnology, since the development of techniques of nanotechnology might be guided by studying the structure and function of the natural nano-molecules found in living cells. Biology offers a window into the most sophisticated collection of functional nanostructures that exists.
This book is a comprehensive review of the state of the art in bio-nanotechnology with an emphasis on the diverse applications in food and nutrition sciences, biomedicine, agriculture and other fields. It describes in detail the currently available methods and contains numerous references to the primary literature, making this the perfect “field guide” for scientists who want to explore the fascinating world of bio-nanotechnology. Safety issues regarding these new technologies are examined in detail.
The book is divided into nine sections – an introductory section, plus:Nanotechnology in nutrition and medicine Nanotechnology, health and food technology applications Nanotechnology and other versatile applications Nanomaterial manufacturing Applications of microscopy and magnetic resonance in nanotechnology Applications in enhancing bioavailability and controlling pathogens Safety, toxicology and regulatory aspects Future directions of bio-nanotechnology
The book will be of interest to a diverse range of readers in industry, research and academia, including biologists, biochemists, food scientists, nutritionists and health professionals.
The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field.
Includes models of aging, including worm, mouse and humanExplores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle healthEncompasses a variety of lifestyle impacts, including diet, exercise and nutritionIncludes suggested nutritional interventions
Drawing from an extensive list of esteemed international contributors, Anti-Angiogenic Functional and Medicinal Foods explores the history and scope of the use of conventional foods, nutraceuticals, and health products in North America, Europe, the Middle East, Asia, India, Australia, and New Zealand. Recent advancements in proteomics, genomics, and toxicogenomics give us a far more detailed picture of the molecular basis of nutrition and systems toxicology. Explaining the role of angiogenesis in various chronic diseases, individual chapters consider endothelial cell responses, the mechanism of the angiogenic cascade, and the angiogenic function involved in tumors, cardiovascular disease, inflammatory arthritis, and obesity. A collection of chapters studies specific foods and their functional bioactive compounds such as the effects of edible berry anthocyanins, various Chinese medicinal foods, dietary flavonoids, probiotics, shark cartilage, EPA and DHA, and marine polysaccharides. The book concludes with a discussion of the challenges faced during the development and delivery of anti-angiogenic functional food products.
Presenting the current research and state of the science, Anti-Angiogenic Functional and Medicinal Foods provides researchers, scientists, clinical nutritionists, and oncologists with a valuable reference to this important and growing mode of therapy.