Tandy Warnow is a Founder Professor of Engineering at the University of Illinois, Urbana-Champaign. Her awards include the National Science Foundation Young Investigator Award (1994), the David and Lucile Packard Foundation Award in Science and Engineering (1996), a Radcliffe Institute for Advanced Study Fellowship (2003), and a John Simon Guggenheim Memorial Foundation Fellowship (2011). She was elected a Fellow of the Association for Computing Machinery (ACM) in 2015, and of the International Society for Computational Biology (ISCB) in 2017.
The book explores Bayesian techniques and models for detecting differentially expressed genes, classifying differential gene expression, and identifying biomarkers. It develops novel Bayesian nonparametric approaches for bioinformatics problems, measurement error and survival models for cDNA microarrays, a Bayesian hidden Markov modeling approach for CGH array data, Bayesian approaches for phylogenic analysis, sparsity priors for protein-protein interaction predictions, and Bayesian networks for gene expression data. The text also describes applications of mode-oriented stochastic search algorithms, in vitro to in vivo factor profiling, proportional hazards regression using Bayesian kernel machines, and QTL mapping.
Focusing on design, statistical inference, and data analysis from a Bayesian perspective, this volume explores statistical challenges in bioinformatics data analysis and modeling and offers solutions to these problems. It encourages readers to draw on the evolving technologies and promote statistical development in this area of bioinformatics.
The book begins with discussions on key HMM and related profile methods, incl
This new edition is updated throughout to Python 3 and is designed not just to help scientists master the basics, but to do more in less time and in a reproducible way. New developments added in this edition include NoSQL databases, the Anaconda Python distribution, graphical libraries like Bokeh, and the use of Github for collaborative development.
Offering an invaluable source of insights for computer scientists, applied mathematicians, and statisticians, this illuminating volume will also prove useful for graduate courses on computational biology and bioinformatics.
Each chapter focuses on a specific problem in machine learning, such as classification, prediction, optimization, and recommendation. Using the R programming language, you’ll learn how to analyze sample datasets and write simple machine learning algorithms. Machine Learning for Hackers is ideal for programmers from any background, including business, government, and academic research.Develop a naïve Bayesian classifier to determine if an email is spam, based only on its textUse linear regression to predict the number of page views for the top 1,000 websitesLearn optimization techniques by attempting to break a simple letter cipherCompare and contrast U.S. Senators statistically, based on their voting recordsBuild a “whom to follow” recommendation system from Twitter data
The 52 revised full papers presented together with 3 invited contributions were carefully reviewed and selected from 114 submissions. The papers are organized in topical sections on computational geometry, computational biology, computability and complexity theory, graph theory and graph algorithms, automata and Petri net theory, distributed computing, Web-based computing, scheduling, graph drawing, and fixed-parameter complexity theory.
By using concrete examples, minimal theory, and two production-ready Python frameworks—Scikit-Learn and TensorFlow—author Aurélien Géron helps you gain an intuitive understanding of the concepts and tools for building intelligent systems. You’ll learn a range of techniques, starting with simple linear regression and progressing to deep neural networks. With exercises in each chapter to help you apply what you’ve learned, all you need is programming experience to get started.Explore the machine learning landscape, particularly neural netsUse Scikit-Learn to track an example machine-learning project end-to-endExplore several training models, including support vector machines, decision trees, random forests, and ensemble methodsUse the TensorFlow library to build and train neural netsDive into neural net architectures, including convolutional nets, recurrent nets, and deep reinforcement learningLearn techniques for training and scaling deep neural nets