Strong emphasis is placed on the latest, post genomic technologies including DNA macro and microarrays, genome-wide two hybrid analysis, proteomics and bioinformatics.
- A modern post-genome era introduction to key techniques used in genetic engineering.
- An example driven past-to-present approach to allow the experiments of today to be placed in an historical context
- The book is beautifully illustrated in full-colour throughout.
- Associated website including updates, additional content and illusions
Many larger endowments and foundations have adopted a broadly diversified asset allocation strategy with only a small amount of traditional U.S. equities and bonds. This technique, known as the "endowment model of investing," has demonstrated consistent long-term performance and attracted the attention of numerous institutional and individual investors.
With The Endowment Model of Investing Leibowitz, Bova, and Hammond take a closer look at the endowment model with customary research sophistication and attention to detail. Throughout the book, they examine how the model provides truly outstanding real returns, while keeping a close eye on the risks associated with this method of investing. Along the way, the authors offer practical advice on incorporating the endowment model into your own investment endeavors and reveal what it takes to make this method work in the real world.
- Details the growing debate about the endowment model of investing and discusses how to use it successfully
- Written by an authority on endowment investing and non-traditional asset allocation strategies
- Offers expert insights on understanding risk and return in non traditional asset allocation
If you want to gain a better grasp of one of the most successful forms of investing, then The Endowment Model of Investing is a book you need to read.
The new ICRF Handbook of Genome Analysis is the essential guide to the enormous range of techniques available to the researcher for both the genetic and physical mapping of the genome, as well as the sequencing and analysis of DNA. It is both a protocol manual and a comprehensive information resource. Written by international experts, each chapter presents a state-of-the-art review of a methodology. Methods are fully described and evaluated; their advantages and disadvantages discussed; and their suitability for different investigations considered. Step-by-step protocols, including computer analyses, are given for 123 essential experimental procedures. 'Troubleshooting' sections discuss possible reasons for failure and offer remedies. The primary focus is on human genetics and the benefits of an understanding of the genome for the diagnosis and treatment of human disease. The book also considers the current state of progress in the analysis of genomes of many model organisms, including plants. A major part of the work provides detail on Internet resources as well as basic data on human and other genomes, including mapped disease genes and mouse knockouts.
- Covers not only the human genome in relation to cancers and other human diseases, but also the genomes of all important model organisms
- Contains 123 easy-to-follow protocols for essential experimental procedures
- Reviews a vast range of other information resources, including journals and the Internet * provides an invaluable listing of suppliers of laboratory materials
- Has been written by international experts from their own practical experience
- Is mandated by the Imperial Cancer Research Fund - a leader in research in this field
- Has a sturdy spiral binding within a hardback case for ease of use in the lab
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In clear, lively prose, The Science and Ethics of Engineering the Human Germ Line: Mendel's Maze provides an authoritative treatment of the principles of science and bioethics that bear upon such technologies as germ-line insertion and cloning. It offers a realistic assessment of possible applications, limitations, and new developments likely to arise in these areas.
Written by a top physician-investigator, this book progresses from the basics of building a living organism from inanimate parts through to recombinant DNA technology, assisted reproductive technologies, and gene transfer and germ-line engineering. Ethical considerations are woven into this material throughout, while a special section covers the intellectual role played by various social biases.
As genetic and reproductive technologies spread from the laboratory to the clinic-and society takes further notice-students and practitioners of biology and medicine, as well as the interested general reader, will find The Science and Ethics of Engineering the Human Germ Line: Mendel's Maze to be an essential and accessible guide to these important subjects.